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| Patent # | Description |
|---|---|
| 2011/0243968 |
THERAPEUTIC APPLICATIONS OF P53 ISOFORMS IN REGENERATIVE MEDICINE, AGING
AND CANCER The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor... |
| 2011/0243967 |
MOLECULAR COMPLEXES WHICH MODIFY IMMUNE RESPONSES Extracellular domains of transmembrane heterodimeric proteins, particularly T cell receptor and major histocompatibility complex proteins, can be covalently... |
| 2011/0243966 |
SINGLE CHAIN Fc (ScFc) REGIONS, BINDING POLYPEPTIDES COMPRISING SAME, AND
METHODS RELATED THERETO The present invention features inter alia polypeptides comprising an Fc region comprising genetically-fused Fc moieties. In addition, the instant invention... |
| 2011/0243965 |
ANTIBODIES AGAINST DOMAINS OF LAMININ-332 Antibodies against various domains of laminin-332 are discussed herein. The antibodies reduce the adhesion and matrix binding properties of laminin-332,... |
| 2011/0243964 |
TREATMENT OF ORTHOPEDIC CONDITIONS Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin agents for treatment of orthopedic disorders, diseases, or... |
| 2011/0243963 |
ANTIBODIES TO LRP6 Anti-LRP6 antibodies and antigen-binding fragments thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding fragments are... |
| 2011/0243962 |
THERAPEUTIC USE OF SPECIFIC LIGAND IN MSRV ASSOCIATED DISEASES The present invention deals with a ligand comprising each of the complementary-determining regions (CDRs) set forth in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3... |
| 2011/0243961 |
METHODS FOR TREATING BONE CANCER BY ADMINISTERING A NERVE GROWTH FACTOR
ANTAGONIST ANTIBODY The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by... |
| 2011/0243960 |
METHODS AND COMPOSITIONS FOR TREATING P. ACNES The disclosure provides an antigenic composition useful for immunization against P. acnes, K. pneumoniae, S. aureus, or Streptococcus pyogenes. The disclosure... |
| 2011/0243959 |
MODULATING NEURONAL PLASTICITY AND TREATMENT OF NEURONAL LOSS BY
MODULATIONG WNT7A OR WNT7B MODULATION The present invention relates to a method of treating or preventing a disease characterized by a loss or imbalance of neuronal connections, wherein said disease... |
| 2011/0243958 |
ANTIMICROBIAL AGENTS THAT TARGET BACTERIAL VKOR Aspects of the invention relate to a method for inhibiting the growth of a microbe that expresses bacterial vitamin K epoxide reductase (bVKOR). The method... |
| 2011/0243957 |
MATERIALS AND METHODS FOR PREVENTING OR TREATING NEURODEGENERATIVE
CONDITIONS ASSOCIATED WITH ABETA PEPTIDE... The subject invention concerns methods for preventing and/or treating neurodegenerative conditions associated with Abeta peptide accumulation in neural tissue... |
| 2011/0243956 |
METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY Disclosed herein are methods for diagnosing a pregnancy related hypertensive disorder or a predisposition to a pregnancy related hypertensive disorder by... |
| 2011/0243955 |
ANTIBODY AND USES THEREOF Described are specific binding members e.g. antibodies which may be used in the treatment of diseases associated with cathepsin S activity. The specific binding... |
| 2011/0243954 |
PEPTIDES CAPABLE OF BINDING TO SERUM PROTEINS AND COMPOUNDS, CONSTRUCTS
AND POLYPEPTIDES COMPRISING THE SAME Provided are pharmaceutical compositions, preparations or formulations including a compounds or constructs that include at least one amino acid sequence that is... |
| 2011/0243953 |
NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including... |
| 2011/0243952 |
COMPOUND AND METHOD FOR REGULATING PLASMINOGEN ACTIVATION AND CELL
MIGRATION The invention relates to novel regulators of plasminogen activation and their use for regulating cell migration, plasminolysis, angiogenesis, fibrinolysis, for... |
| 2011/0243951 |
IMMUNOMODULATING TUMOR NECROSIS FACTOR RECEPTOR 25 (TNFR25) AGONISTS,
ANTAGONISTS AND IMMUNOTOXINS It is an object of the invention to provide novel compositions and methods utilizing immunomodulating agents that can either stimulate or indirectly augment the... |
| 2011/0243950 |
MSP2 ANTIGENIC PEPTIDES AND THEIR USE This invention relates generally to the field of P. falciparum antigens and their use, for example, for the preparation of a vaccine against said pathogen. More... |
| 2011/0243949 |
COMPOSITION FOR PRODUCING ANTI-AMYLOID BETA PEPTIDE ANTIBODIES WITH
D-PEPTIDES The present invention relates to a composition comprising D-peptides or antibodies for use as a therapeutic and/or for disease prevention, wherein a) the... |
| 2011/0243948 |
Monoclonal Antibodies Against ANGPTL3 Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided.... |
| 2011/0243947 |
ANTIBODIES AGAINST CSF-1R The invention provides a human antibody that binds human CSF-1R with high affinity. Antibodies of the present invention have significant advantages over the... |
| 2011/0243946 |
Remedies for pemphigus containing anti Fas ligand antibodies The present invention refers to the use of FasL antagonists, e.g. of humanized antibodies directed against human Fas ligands (also named CD95L or Apo1L and... |
| 2011/0243945 |
Anti-Inflammatory Agents This invention is in the field of treating or preventing inflammation in humans and animals and relates to pharmaceutical compositions and methods for treating... |
| 2011/0243944 |
Fusion Protein Inhibiting Osteoclast Formation, Preparation Method and
Medicine Compositions Thereof The present invention provides a coding gene having the nucleic acid sequence shown as SEQ ID NO:1 and the fusion protein RIG (SEQ ID NO:2) that inhibits... |
| 2011/0243943 |
TREATMENT USING RELAXIN-FUSION PROTEINS WITH EXTENDED IN VIVO HALF-LIVES Disclosed are human relaxin-Fc fusion proteins having an increased serum half-life, polynucleotides encoding the same, and intermediates formed during the... |
| 2011/0243942 |
RELAXIN-FUSION PROTEINS WITH EXTENDED IN VIVO HALF-LIVES Disclosed are human relaxin-Fc fusion proteins having an increased serum half-life, polynucleotides encoding the same, and intermediates formed during the... |
| 2011/0243941 |
Identification and Engineering of Antibodies with Variant Fc Regions and
Methods of Using Same The present invention relates to molecules, particularly polypeptides, more particularly immunoglobulins (e.g., antibodies), comprising a variant Fc region,... |
| 2011/0243940 |
BICYCLIC PYRANONE DERIVATIVES AND METHODS OF USE THEREOF The present invention relates to Bicyclic Pyranone Derivatives, their compositions and uses for treating or preventing a metabolic disorder, dyslipidemia, a... |
| 2011/0243939 |
MODIFICATION OF NUCLEIC ACID VECTORS WITH POLYMERS COMPRISING CHARGED
QUATERNARY AMINO GROUPS The present invention provides a polymer modified nucleic acid vector in which the nucleic acid vector is covalently linked to a polymer, which polymer... |
| 2011/0243938 |
Methods to Reduce B-Helper T Cells to Treat Autoimmune Diseases The present invention includes compositions and methods for the treatment of autoimmune diseases by administering to a subject having an autoimmune disorder an... |
| 2011/0243937 |
TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment... |
| 2011/0243936 |
TNFalpha-NEUTRALIZING ANTIBODIES The invention provides monoclonal antibodies that neutralize TNF.alpha. activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal... |
| 2011/0243935 |
Compositions and Methods for Immunotherapy The invention relates to immunotherapeutic compounds, compositions that include such compounds, and methods of using the compounds, for example, to treat an... |
| 2011/0243934 |
EPHA3 ANTIBODIES FOR THE TREATMENT OF MULTIPLE MYELOMA The invention provides methods and compositions comprising anti-EphA3 antibodies for the treatment of multiple myeloma. |
| 2011/0243933 |
Perifosine and Capecitabine as a Combined Treatment for Cancer Treatment regimens comprising co-treatment of cancer with perifosine and capecitabine are disclosed herein, as well as pharmaceutical compositions and unit... |
| 2011/0243932 |
ANTI-CD40 ANTIBODIES The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same. |
| 2011/0243931 |
COMBINATION THERAPY WITH TYPE I AND TYPE II ANTI-CD20 ANTIBODIES The present application is directed to the combination therapy of a type I and a type II anti-CD20 antibody for the treatment of cancer, especially of CD20... |
| 2011/0243930 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune... |
| 2011/0243929 |
ANTI-ICOS ANTIBODIES AND THEIR USE IN TREATMENT OF ONCOLOGY,
TRANSPLANTATION AND AUTOIMMUNE DISEASE The present invention provides anti-human ICOS antibodies with increased effector function. The invention further relates to pharmaceutical compositions,... |
| 2011/0243928 |
CHIMERIC AND HUMANISED MONOCLONAL ANTIBODIES AGAINST INTERLEUKIN-13 The present invention concerns immunoglobulins, particularly antibodies which specifically bind human Interleukin 13 (hIL-13). Antibodies of the invention may... |
| 2011/0243927 |
METHODS OF INHIBITING TUMOR GROWTH USING BETA 5 INTEGRIN ANTAGONISTS The present invention relates to methods for treating cancer by administering to a mammalian subject a therapeutically effective amount of a selective... |
| 2011/0243926 |
ANTI-P-SELECTIN ANTIBODIES AND METHODS OF USING THE SAME TO TREAT
INFLAMMATORY DISEASES The invention features antibodies, e.g., chimeric and humanized antibodies, that recognize (i.e., bind) P-selectin. The P-selectin antibodies prevent P-selectin... |
| 2011/0243925 |
Gene Expression Profiles Being Predictive for the Response of Tumors to
Pharmaceutically Effective Compounds The present invention relates to a method for providing a gene expression profile being predictive for the specific response of an individual tumor to a... |
| 2011/0243924 |
NOVEL METHODS The invention provides methods of inhalation treatment of a respiratory disease or condition in a patient in need to such treatment without producing in said... |
| 2011/0243923 |
ORGANIC COMPOUNDS The present invention relates to modulators of the interaction between Epstein-Barr Virus induced receptor-2 (EBi2) and cholest-5-ene-3b,7b,25-triol (7,... |
| 2011/0243922 |
Genetic Alterations Associated with Type I Diabetes and Methods of Use
Thereof for Diagnosis and Treatment Compositions and methods for the detection and treatment of T1D are provided. |
| 2011/0243921 |
PREVENTION AND TREATMENT OF CUTANEOUS LUPUS ERYTHEMATOSUS Disclosed herein, in certain embodiments, are methods and compositions for the prevention and treatment of autoimmune disease. Further disclosed herein, in... |
| 2011/0243920 |
COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product... |
| 2011/0243919 |
Compositions and Methods for Treating Collagen-Mediated Diseases A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product... |
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