BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE
A branched hetero polyethylene glycol according to the present invention is represented by the formula : ##STR00001## wherein X and Y represent each an atomic...
ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE,
ELECTRONIC DEVICE, AND LIGHTING DEVICE
A novel substance with which an increase in life and emission efficiency of a light-emitting element can be achieved is provided. A carbazole compound having a...
NOVEL PREPARATION OF ANTICANCER-ACTIVE TRICYCLIC COMPOUNDS VIA ALKYNE
The present invention is directed to provide a novel preparation of anticancer-active tricyclic compounds via alkyne coupling reaction. The present invention...
PROCESS FOR PRODUCING FUSED IMIDAZOLE COMPOUND, REFORMATSKY REAGENT IN
STABLE FORM, AND PROCESS FOR PRODUCING...
The present invention provides an industrially advantageous process for producing a steroid C.sub.17,20 lyase inhibitor represented by the general formula (I); ...
Process For Preparing Epothilone Derivatives By Selective Catalytic
The present invention describes a novel process for preparing an epothilone derivative using substituted pyridines and methyltrioxorhenium as catalyst.
LEAD-FREE PRIMARY EXPLOSIVE COMPOSITION
Embodiments of the present subject matter provide a compound and material that may be used as a lead-free primary explosive. An embodiment of the present...
Methods for Synthesizing 3-(Substituted Dihydroisoindolinone-2-YL)-2,
6-Dioxopiperidine, and Intermediates Thereof
The present invention discloses methods for synthesizing 3-(substituted dihydroisoindolinone-2-yl)-2,6-dioxopiperidine and intermediates thereof, namely, the...
N[S(4-ARYL-TRIAZOL-3-YL)ALPHA-MERCAPTOACETYL]-P-AMINO BENZOIC ACIDS AS HIV
REVERSE TRANSCRIPTASE INHIBITORS
A series of S-triazolyl .alpha.-mercaptoacetanilides having N-(.alpha.-mercaptoacetyl) p amino benzoic acid derivatives. ##STR00001## are provided, where Q is...
METHOD FOR PRODUCING A SOLID PREPARATION
A method for producing a solid preparation containing a compound represented by the formula (I) below or a pharmacologically acceptable salt thereof, which...
6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors
Compounds of the formula ##STR00001## and pharmaceutically acceptable salts thereof, wherein X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5, X.sub.6, X.sub.7,...
Structure Based Design Of Inhibitors Of Human Thymidylate Synthase
A compound is provided having the chemical structure: ##STR00001## where R1 is H, CH.sub.3, a tert-butyl group, C(.dbd.O)-Glu, C(.dbd.O)-Asp, C(.dbd.O)-Gln,...
PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N,N-SUBSTITUTED AMINO
The present invention relates to a process for preparing (meth)acrylic esters (F) of N,N-substituted amino alcohols, by transesterifying N,N-substituted amino...
CAMPHOR-DERIVED COMPOUNDS, METHOD FOR MANUFACTURING THE SAME, AND
Camphor-derived compounds are disclosed, which are represented as the following formula (I): ##STR00001## wherein R.sub.1, R.sup.2, R.sub.3, and R.sub.4 each are...
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHOD OF USE
The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-.beta.) inhibitors thereby regulating angiogenesis. The...
REDOX DRUG DERIVATIVES
The present invention provides redox drug derivatives. In particular, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido- ...
Sulphonylated Diphenylethylenediamines, Method for Their Preparation and
Use in Transfer Hydrogenation Catalysis
A diamine of formula (I) is described in which A is hydrogen or a saturated or unsaturated C1-C20 alkyl group or an aryl group; B is a substituted or...
Chlorination of sucrose-6-esters
A method for the chlorination of a sucrose-6-acylate to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-.beta.-acylate wherein said method...
Optimization of Nucleation and Crystallization for Lyophilization Using
This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of...
METHOD FOR PREPARING MOLECULAR COMPLEXES BETWEEN ADAPALENE AND
A method for preparing molecular complexes between Adapalene and cyclodextrins using the technology of dense fluids under pressure, especially that of CO2 is...
NUCLEIC ACID PURIFICATION METHOD
The present invention relates to a method for purifying a defined amount of nucleic acids from a nucleic acid-containing sample, which has at least the...
NUCLEIC ACID SEQUENCES ENCODING AN1-LIKE ZINC FINGER PROTEINS
Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants.
NOVEL TECHNETIUM AND RHENIUM COMPLEXES
Novel radioactive technetium and rhenium complexes comprising tripodal ligands are provided by the present invention. In particular, Tc(I) complexes are...
POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCE AND METHODS THEREOF
The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human...
NON-AQUEOUS SYNTHESIS OF POLYSACCHARIDE-PROTEIN CONJUGATES FOR VACCINES
The invention is a novel chemical coupling methodology for the synthesis of a stable polysaccharide-protein conjugates as the immunogenic component for...
ANTAGONISTS OF PCSK9
Antagonists of human proprotein convertase subtilisin-kexin type 9 ("PCSK9") are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9...
METHOD FOR REMOVING VIRUSES FROM HIGH CONCENTRATION MONOCLONAL ANTIBODY
An object of the present invention is to provide a method for removing even small viruses from a high concentration monoclonal antibody solution using a...
HUMANIZED ANTI-PROSTATE STEM CELL ANTIGEN MONOCLONAL ANTIBODY
Prostate stem cell antigen (PSCA) is expressed in the majority of prostate cancer patients, making it an ideal target for cancer immunotherapy. Murine...
ENHANCED PURIFICATION OF ANTIBODIES AND ANTIBODY FRAGMENTS BY APATITE
Methods are disclosed for use of apatite chromatography, particularly without reliance upon phosphate gradients, for purification or separation of at least one...
FLUOROBODIES: INTRINSICALLY FLUORESCENT BINDING LIGANDS
Binding ligands with intrinsic fluorescence ("fluorobodies"), fluorobody libraries, and methods of preparing fluorobodies are provided. In one aspect, the...
Asymmetric Cobalt-Catalyzed Cyclopropanation With Succinimidyl
Cobalt(II) complexes of the D.sub.2-symmetric chiral porphyrins are effective catalysts for asymmetric cyclopropanation reactions with succinimidyl...
Multimodal Imaging of Fibrin
Fibrin-specific imaging agents that contain at least two imaging reporters are described, as well as methods of making and using the contrast agents.
Lactam-Bridged Melanocortin Receptor-Specific Peptides
Lactam-bridged melanocortin receptor-specific cyclic peptides of the formula ##STR00001## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, ...
Method of Producing Polymeric Phenazonium Compounds
A process of making a polymeric phenazonium compound having the general formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.4, R.sup.5, R.sup.6, R.sup.8 and...
HOLE TRANSPORT POLYMERS
There is provided a polymer made from a monomer having Formula I: ##STR00001## where: R and Y are independently selected from the group consisting of H, D,...
PROCESS FOR REDUCING MOISTURE IN A BIODEGRADABLE IMPLANT DEVICE
The disclosed process comprises freeze-drying a biodegradable implant device comprised or one or more polyesters to thereby reduce moisture content in the device.
SYNTHESIS OF TRI-COMPONENT RESINS
A resinous compound of the formulas ##STR00001## or a salt thereof, wherein G.sub.1 is --X.sub.1C(O)OR.sub.1,--X.sub.2OC(O)R.sub.2, or --X.sub.2OH; G.sub.2 is ...
PROCESS FOR THE PREPARATION OF COPOLYMER - 1 (COP-1), COMPOSED OF
L-ALANINE, L-LYSINE, L-GLUTAMIC ACID AND...
A process for the synthesis of copolymer-1 composed of L-alanine, LHysine, L-glutamic acid and L-tyrosine for the treatment of multiple sclerosis. The molecular...
METHOD FOR INCREASING THE MOLECULAR WEIGHT OF A POLYESTER GRANULATE BY
USING ITS RESIDUAL HEAT
The present invention relates to increasing the molecular weight during a thermal treatment of polyester in combination with a latent heat granulation. With the...
Compound Suitable as Polymeric Dispersant
A compound according to the present invention is obtainable by reacting a polyisocyanate with a monoalkylether of a polyoxyalkylenemonoamine, in such an amount...
Organic semiconductor copolymers containing oligothiophene and n-type
An exemplary organic semiconductor copolymer includes a polymeric repeat structure having a polythiophene structure and an electron accepting unit. The electron...
The invention relates to a method of making a polypeptide comprising an orthogonal functional group, said orthogonal functional group being comprised by an...
METHOD FOR PRODUCING (METH) ACRYLIC ACID
The objective of the present invention is to provide a method for efficiently producing (meth)acrylic acid by crystallization using a plurality of crystallizer...
CATIONICALLY POLYMERIZABLE RESIN COMPOSITION AND CURED OBJECT OBTAINED
Disclosed is a cationically polymerizable resin composition which includes an oxetane-ring-containing vinyl ether compound (A) and/or an ...
Novel Class Of Olefin Metathesis Catalysts, Methods Of Preparation, And
Processes For The Use Thereof
This invention relates to a metathesis catalyst comprising (i) a Group 8 metal hydride-dihydrogen complex represented by the formula: ##STR00001## wherein M is a...
Catalyst Components for the Polymerization of Olefins and Catalysts
Catalyst components for the polymerization of olefins CH.sub.2.dbd.CHR wherein R is hydrogen or a hydrocarbon radical having 1-12 carbon atoms, comprising Mg,...
Low Temperature Curable Epoxy Compositions
A heat curable epoxy composition comprising the contact product of an epoxy resin, an epoxy curing agent and an accelerator for the epoxy curing agent, the...
Materials Comprising a Matrix and Process for Preparing Them
The present invention is concerned with a material comprising: a matrix material comprising a plurality of urethane and/or urea and/or isocyanurate groups and...
POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS
A method for preparing a functionalized polymer, the method comprising the steps of (i) polymerizing conjugated diene monomer by employing a lanthanide-based...
Method For Preparing A Superplasticizer
The invention chiefly concerns a method for preparing polyalkoxylated polycarboxylates in which the following are caused to react in the presence of water and a...
FLUORORUBBER MOLDED ARTICLE
The present invention provides a fluororubber formed product having excellent heat resistance and excellent mechanical properties at high temperatures. The...