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Patent # Description
2016/0096914 URETHANES, POLYMERS THEREOF, COATING COMPOSITIONS AND THEIR PRODUCTION FROM CYCLIC CARBONATES
The present invention relates to functionalized cyclic carbonates, urethanes and polyurethanes, their methods of production and uses thereof.
2016/0096913 BIOSTABLE POLYURETHANES
The present invention relates to a biostable polyurethane or polyurea comprising: (a) a soft segment comprising a polysiloxane of the general formula (I); and...
2016/0096912 LOW VINYL STYRENE-BUTADIENE POLYMERS AND METHODS OF MAKING THE SAME
The invention provides a process for the continuous polymerization of a polymer comprising monomeric units derived from styrene and 1,3-butadiene, said process...
2016/0096911 SURFACE TREATMENT AGENT AND MEDICAL DEVICE
Provided are surface treatment agents that enable surfaces with a chemically fixed lubricant to be produced instead of a resin coating which has drawbacks,...
2016/0096910 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME
Conjugated diene polymer comprising at least a conjugated diene monomer unit, the conjugated diene polymer has a number-average molecular weight (Mn) in terms...
2016/0096909 Method for Producing Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer, and...
A method for producing a modified conjugated diene-based polymer having a good balance between the hysteresis loss properties and the wet skid resistance,...
2016/0096908 LOW MOLECULAR WEIGHT GRAFT POLYMER FOR SCALE INHIBITOR
The presently disclosed and/or claimed concept(s) relates generally to a composition comprising a low molecular weight graft polymer. The graft polymer is a...
2016/0096907 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER...
The present teachings show that it is possible to polymerize 1,1-disubstituted alkene compounds in an emulsion (for example using a water based carrier...
2016/0096906 SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS,...
The present teachings show that it is possible to polymerize 1,1-disubstituted alkene compounds in a solution (for example using one or more solvents)....
2016/0096905 Reduction of Endotoxin in Polysialic Acids
The present invention relates to process for reducing the endotoxin content of a sample of fermentation broth containing polysialic acid and endotoxin...
2016/0096904 SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME
A superhydrophilic amphiphilic copolymer and process for making the superhydrophilic amphiphilic copolymer includes a low molecular weight polysaccharide...
2016/0096903 HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK
The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a...
2016/0096902 CHIMERIC ANTIGEN RECEPTOR-TARGETING MONOCLONAL ANTIBODIES
Provided are monoclonal antibodies that detect CD 19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they...
2016/0096901 ANTI-CD38 HUMAN ANTIBODIES AND USES THEREOF
The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are...
2016/0096900 QSOX1 as an Anti-Neoplastic Drug Target
The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such...
2016/0096899 METHODS FOR TREATING JUVENILE ARTHRITIS WITH ANTI-BILE SALT-STIMULATED LIPASE (BSSL) ANTIBODIES
It provides methods and pharmaceutical compositions comprising antagonists to the protein Bile Salt-Stimulated Lipase (BSSL) for the prevention, prophylaxis...
2016/0096898 PC33718E
The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type...
2016/0096897 ANTIBODIES TO MASP-2
The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of...
2016/0096896 TWEAK/FN14 SYSTEM REGULATES SKELETAL MUSCLE ATROPHY AND REGENERATION
The invention provides methods for preventing loss and augmenting regeneration of skeletal muscle by decreasing the activity of the TWEAK/Fn14 system.
2016/0096895 BINDING MEMBERS-513
This invention relates to binding members, especially antibody molecules, specific for interleukin 1 receptor 1 (IL-1R1). For example, isolated binding members...
2016/0096894 ANTIBODIES TO INSULIN-LIKE GROWTH FACTOR I RECEPTOR
The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR),...
2016/0096893 ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES
The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
2016/0096892 TREATMENT OF CANCER USING A CD33 CHIMERIC ANTIGEN RECEPTOR
The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen...
2016/0096891 ANTI-B7-H5 ANTIBODIES AND THEIR USES
The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to the...
2016/0096890 B7-H1, A NOVEL IMMUNOREGULATORY MOLECULE
The invention provides novel polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid...
2016/0096889 B7-H1, A NOVEL IMMUNOREGULATORY MOLECULE
The invention provides novel polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid...
2016/0096888 Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using...
2016/0096887 Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using...
2016/0096886 METHODS FOR ADMINISTERING ANTI-IL-5 ANTIBODIES
The present invention relates generally to the methods for the treatment and diagnosis of conditions mediated by IL-5 and excess eosinophil production, and...
2016/0096885 DISTINCT EFFECTS OF IFN-GAMMA AND IL-17 ON TL1A MODULATED INFLAMMATION AND FIBROSIS
Described herein are methods and compositions related to Inflammatory Bowel Disease. Specifically TL1A drives regional intestinal inflammation and fibrosis and...
2016/0096884 ANTIBODIES DIRECTED AGAINST AMYLOID-BETA PEPTIDE AND METHODS USING SAME
Antibodies directed to the C-terminal side of .beta.-amyloid peptide and methods of using these antibodies for diagnosing and treatment of Alzheimer's disease...
2016/0096883 GLIOBLASTOMA MULTIFORME-REACTIVE ANTIBODIES AND METHODS OF USE THEREOF
The present disclosure is generally related to antibodies that bind specifically to glioblastoma multiforme (GBM) cells. In particular, the present disclosure...
2016/0096882 NEUTRALIZING MOLECULES TO INFLUENZA VIRUSES
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the...
2016/0096881 MEANS AND METHODS FOR PRODUCING HIGH AFFINITY ANTIBODIES
The invention provides means and methods for producing high-affinity antibodies against an antigen of interest, usually stable B-cell cultures.
2016/0096880 HUMAN CYTOMEGALOVIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and...
2016/0096879 Viscosity-Reducing Excipient Compounds for Protein Formulations
The invention encompasses formulations and methods for the production thereof that permit the delivery of concentrated protein solutions. The inventive methods...
2016/0096878 FIBROIN-DERIVED PROTEIN COMPOSITION
The invention provides a protein composition derived from silk fibroin, which composition possesses enhanced solubility and stability in aqueous solutions. The...
2016/0096877 APOE PEPTIDE DIMERS AND USES THEREOF
The present invention provides novel pharmaceutical compositions comprising ApoE-derived peptide dimers. In particular, the ApoE peptide dimers of the...
2016/0096876 COMPOSITIONS AND METHODS OF TREATING DISEASE WITH FGFR FUSION PROTEINS
The invention provides FGFR fusion proteins, methods of making them, and methods of using them to treat proliferative disorders, including cancers and...
2016/0096875 CODON OPTIMIZED IL-15 AND IL-15R-ALPHA GENES FOR EXPRESSION IN MAMMALIAN CELLS
The present invention provides for nucleic acids improved for the expression of interleukin-15 (IL-15) in mammalian cells. The invention further provides for...
2016/0096874 MRG RECEPTOR MODULATORS
The present invention is in the field of molecular biology, more particularly, the present invention relates to drug screening, assay development and...
2016/0096873 PEPTIDOMIMETIC MACROCYCLES
The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides,...
2016/0096872 METHODS FOR PRODUCING PEPTIDES USING ENGINEERED INTEINS
The present invention provides a method for producing peptides by recombinant means. The peptides are expressed as part of a fusion protein comprising the...
2016/0096871 Methods and Reagents for Treatment of Age-Related Macular Degeneration
The invention relates to Factor H gene polymorphisms and haplotypes associated with an elevated or a reduced risk of AMD. The invention provides methods and...
2016/0096870 COMPLEMENT INHIBITORS
The invention relates to complement inhibitors that inhibit both the classical and alternative complement pathways. In particular, the invention relates to...
2016/0096869 CHLOROTOXIN CONJUGATES AND METHODS OF USE THEREOF
Compositions, formulations and kits comprising chlorotoxin conjugate compounds are provided, including native and modified variants of chlorotoxin peptide...
2016/0096868 Mussel-inspired bioactive surface coating composition generating silica nanoparticles
The present invention relates to a fusion protein comprising a mussel adhesive protein and a silica-binding peptide linked to the mussel adhesive protein, a...
2016/0096867 CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
The present invention relates to .gamma.-PNA monomers according to Formula I where substituent groups R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, B...
2016/0096866 POTENT COMPSTATIN ANALOGS
Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display...
2016/0096865 Peptide-Silica Hybrid Materials
The invention relates to novel peptide-silane "hybrid block" molecules, to the synthesis thereof and to the use of same for producing novel peptide-silica...
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