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Patent # Description
2016/0095864 COMPOSITION FOR REDUCING CELL SENESCENCE COMPRISING RHO-KINASE INHIBITOR AND USE THEREOF
A composition for reducing cell senescence including a Rho-kinase inhibitor and method of treating a cell senescence-related symptom in mammals.
2016/0095863 COMBINATION TREATMENT OF ACUTE MYELOID LEUKEMIA and MYELODYSPLASTIC SYNDROME
The present invention relates to the use of Volasertib or a salt thereof or the hydrate thereof in combination with Quizartinib or a salt thereof or the...
2016/0095862 Methods and Devices for Renal Nerve Blocking
Drug eluting implants for targeted delivery of a nerve-blocking agent to inhibit neural traffic along renal nerves of a human patient.
2016/0095861 OPHTHALMIC OINTMENTS COMPRISING VALGANCICLOVIR HYDROCHLORIDE FOR TREATING INFECTIVE EYE DISEASES
The present invention provides ophthalmic ointments for treating infective eye diseases containing valganciclovir hydrochloride as an active ingredient in the...
2016/0095860 Pharmaceutical Composition Comprising Progestogens and/or Estrogens and 5-Methyl-(6S)-tetrahydrofolate
The present invention relates to a pharmaceutical composition which comprises progestogens, preferably drospirenone, estrogens, preferably ethinylestradiol and...
2016/0095859 COMBINATION THERAPIES FOR OVERCOMING RESISTANCE TO MITOTIC AGENTS DURING CHEMOTHERAPY
This disclosure relates to the uses of compounds that target an interaction between CHFR and PARP1. In certain embodiments, the disclosure relate to treating...
2016/0095858 Modulators of Cystic Fibrosis Transmembrane Conductance Regulator
The present invention features a compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, where R.sub.1, R.sub.2, R.sub.3, W, X, Y, Z,...
2016/0095857 METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods...
2016/0095856 SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention...
2016/0095855 USE OF A POLYMORPH OF FLIBANSERIN FOR TREATING DISEASE
The invention relates to the polymorph A of flibanserin, to a technical process for the preparation thereof, as well as to the use thereof for preparing...
2016/0095854 ARYLPIPERAZINE OPIOID RECEPTOR ANTAGONISTS
Provided are opioid receptor antagonists represented by the formula (I): ##STR00001## where R, Y.sub.3, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as ...
2016/0095853 USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS
The present invention relates to storage stable prolonged release pharmaceutical dosage forms comprising oxycodone or a pharmaceutically acceptable salt...
2016/0095852 Liposomes Useful for Drug Delivery
The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging...
2016/0095851 SUBLINGUAL APOMORPHINE
The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and...
2016/0095850 METHODS AND COMPOSITIONS FOR TREATMENT OF HIV INFECTION
Methods and compositions for treatment of human immunodeficiency virus (HIV) infections have been developed which dampen immune activation with a bias more on...
2016/0095849 CRYSTALLINE FORM OF A QUINOLINONE-CARBOXAMIDE COMPOUND
The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid ...
2016/0095848 PHENYLPYRROLE DERIVATIVE
Provided are novel compounds that are useful in the prevention or treatment of such diseases as dementia, Alzheimer's disease, attention-deficient...
2016/0095847 DEUTERATED ANALOGS OF PRIDOPIDINE USEFUL AS DOPAMINERGIC STABILIZERS
The present invention provides novel deuterated analogs of Pridopidine, i.e. 4-(3-methanesulfonyl-phenyl)-1-propyl-piperidine. Pridopidine is a drug substance...
2016/0095846 SUBLINGUAL FENTANYL SPRAY
The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable...
2016/0095845 COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER
The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising (S)-(-)-benproperine or a pharmaceutically...
2016/0095844 INDOLIN-2-ONE OR PYRROLO-PYRIDIN/PYRIMIDIN-2-ONE DERIVATIVES
The present invention is concerned with 2-oxo-2,3-dihydro-indoles of general formula ##STR00001## wherein Ar is a 6-membered heteroaryl group, containing one...
2016/0095843 PYRAZOLOPYRROLIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the...
2016/0095842 COMBINATION THERAPY CONTAINING A PI3K-ALPHA INHIBITOR AND FGFR KINASE INHIBITOR FOR TREATING CANCER
A pharmaceutical combination comprising an alpha-isoform specific phosphatidylinositol 3-kinase inhibitor compound of formula (I) or a pharmaceutically...
2016/0095841 PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK
The present invention relates to a compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3,...
2016/0095840 COMBINATIONS OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2 ADRENORECEPTOR AGONIST
Combinations of a muscarinic acetylcholine receptor antagonist and a beta 2 agonist for inhaled administration via the nose or mouth, and methods of using them...
2016/0095839 METHOD OF USING DOPAMINE REUPTAKE INHIBITORS AND THEIR ANALOGS FOR TREATING AUTOIMMUNE CONDITIONS AND DELAYING...
Dopamine reuptake inhibitors, and their analogs, are disclosed for treating and delaying the progression of autoimmune diseases.
2016/0095838 TARGETED POLYMERIC CONJUGATES AND USES THEREOF
Polymeric conjugates comprising a polymeric backbone having attached thereto a bone targeting moiety and a therapeutically active agent, wherein the bone...
2016/0095837 MODULATION OF MITOCHONDRIAL CALCIUM UNIPORTER ACTIVITY FOR TREATING AND PREVENTING ARRHYTHMIAS
Disclosed are methods and compositions for treating or preventing diseases or disorders associated with mitochondrial calcium uniporter (MCU) activity. The...
2016/0095836 Vector Delivery-Based Microbicides
A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided....
2016/0095835 COMPOSITIONS CONTAINING OMEGA-3 OIL AND USES THEREOF
The invention provides pharmaceutical compositions containing omega-3 oil and a non-hydrophilic co-solvent that have an increased absorption rate. The...
2016/0095834 FOOD AND DRINK
The present invention provides a food or drink that emits no offensive odor typified by a fish odor in any form of the food or drink, such as liquid, gel,...
2016/0095833 BRANCHED CHAIN FATTY ACIDS FOR PREVENTION OR TREATMENT OF GASTROINTESTINAL DISORDERS
The present invention is directed to a method of preventing or treating a gastrointestinal condition in a subject, that includes administering one or more...
2016/0095832 TOPICAL COMPOSITION FOR PAIN RELIEF
The composition comprises 0.5% to 10% by weight of a neuropathic analgesic; 0.5% to 10% by weight of a muscle relaxant; 0.5% to 20% by weight of an...
2016/0095831 USE OF HYDROGEN SULFIDE SYNTHESIS INHIBITORS FOR CANCER THERAPY
In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-.beta.-synthase (CBS) inhibitor, or a...
2016/0095830 CO-ADMINISTRATION OF INTRAVENOUS IBUPROFEN AND ACETAMINOPHEN FOR TREATMENT OF PAIN
An effective dose of intravenous ibuprofen administered co-adminstered with intravenous acetaminophen in surgery patients is a safe and effective way to reduce...
2016/0095829 TRPV1 COMPOUNDS IN A BIODEGRADABLE POLYMER CARRIER
Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of a TRPV1 compound (e.g.,...
2016/0095828 Compositions and Methods for Treating Metabolic Disorders
Methods for improving the gastrointestinal tolerability of biguanide compounds and for treating metabolic disorders and/or inducing weight loss in patients in...
2016/0095827 DELAYED RELEASE CYSTEAMINE BEAD FORMULATION, AND METHODS OF MAKING AND USING SAME
An enteric-coated bead dosage form of cysteamine, and related methods of manufacture and use, are disclosed.
2016/0095826 METHODS OF DIAGNOSIS AND TREATMENT
A method for diagnosing a cardiac ischemic event and a kit for detecting biomarkers used in the method. Also provided is a method for treating a PPAR-related...
2016/0095825 ANIMAL TREATMENTS
Compositions and methods for the treatment and control of various conditions in an animal which comprises administering to said animal an effective amount of a...
2016/0095824 USE OF VITAMIN K FOR WEIGHT MAINTENANCE AND WEIGHT CONTROL
Vitamin K is effective in counteracting (1) increase of body weight and body mass index (BMI), (2) accumulation of body fat mass and (3) accelerates weight...
2016/0095823 METHODS OF USING PROPOFOL DERIVATIVES FOR ANALGESIA
The present invention concerns compounds derived from the anaesthetic propofol that are useful as analgesics and methods of using the same. The compounds act...
2016/0095822 Multiparticulate L-Menthol Formulations and Related Methods
A pharmaceutical dosage form includes an effective amount of L-menthol for treating a gastrointestinal disorder. The L-menthol is within a plurality of...
2016/0095821 ABUSE-RESISTANT MUCOADHESIVE DEVICES FOR DELIVERY OF BUPRENORPHINE
The present invention provides abuse deterrent mucoadhesive devices for delivery of buprenorphine. Each device comprises a mucoadhesive layer and a backing...
2016/0095820 METHOD AND PROCESS FOR THE PRODUCTION OF MULTI-COATED RECOGNITIVE AND RELEASING SYSTEMS
The present invention includes compositions, methods, systems and kits for the controlled delivery of an active agent within a polymeric network upon the...
2016/0095819 Pharmaceutical compositions containing flibanserin
The invention relates to oral pharmaceutical compositions containing flibanserin, methods for the preparation thereof and use thereof as a medicament.
2016/0095818 SOLID PHARMACEUTICAL DOSAGE FORM FOR RELEASE OF AT LEAST ONE ACTIVE PHARMACEUTICAL INGREDIENT IN THE ORAL CAVITY
Solid pharmaceutical dosage form for the release of at least one Active Pharmaceutical Ingredient (API) in the oral cavity comprising a core coated by at least...
2016/0095817 Liposomes Useful for Drug Delivery
The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging...
2016/0095816 ARTICLE AND METHODS FOR ORAL SELF-ADMINISTRATION OF NICOTINE
The invention discloses an article for swaddling in the mouth to deliver pharmacologically active substances, particularly nicotine, in combination with dyes...
2016/0095815 SUBSTANCE FOR RESTORING NORMAL CO-EXPRESSION AND INTERACTION BETWEEN THE LOX AND NRAGE PROTEINS
The invention relates to the use of a substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins. The invention relates in...
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