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| Patent # | Description |
|---|---|
| 2016/0102367 |
RECURRENT MUTATIONS IN EPIGENETIC REGULATORS, RHOA AND FYN KINASE IN
PERIPHERAL T-CELL LYMPHOMAS Whole exome sequencing of 12 tumor-normal DNA pairs, RNAseq analysis and targeted deep sequencing identified new genetic alterations in PTCL transformation.... |
| 2016/0102366 |
METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON
BASIS OF PHLDA1 OR PIK3C2B EXPRESSION An object of the present invention is to provide a chemotherapy using a PI3K/AKT/mTOR inhibitor that produces an excellent antitumor effect on a cancer... |
| 2016/0102365 |
ASSAYS, METHODS AND KITS FOR ANALYZING SENSITIVITY AND RESISTANCE TO
ANTI-CANCER DRUGS, PREDICTING A CANCER... Described herein are assays, methods and kits for analyzing sensitivity of a subject's cancerous tumor to a drug, predicting responses of cancerous tumors to... |
| 2016/0102364 |
Neuroglioma Molecular Subtyping Gene Group and Use Thereof A set of gene groups for predicting or for the auxiliary prediction of the survival time prognosis of patients with neuroglioma consists of a PM gene group and... |
| 2016/0102363 |
METHODS AND COMPOSITIONS FOR PREDICTING THERAPEUTIC EFFICACY OF KINASE
INHIBITORS IN PATIENTS WITH... The invention discloses a diagnostic method for predicting the therapeutic efficacy of a broad specificity kinase inhibitor in a subject with refractory cancer... |
| 2016/0102362 |
GEP5 MODEL FOR MULTIPLE MYELOMA The invention provides, inter alia, methods of prognosing a subject with, or suspected of having, multiple myeloma. In certain embodiments, the methods entail... |
| 2016/0102361 |
NEUROTENSIN-INDUCED TUMOR FORMATION IS REGULATED BY MICRO RNA
133A-AFTIPHILIN-DEPENDENT RECEPTOR RECYCLING This application discloses methods of treating, preventing, and diagnosing colorectal cancer and IBD in a subject comprising administering an effective dose of... |
| 2016/0102360 |
GENETIC SIGNATURE OF VULNERABILITY TO INHIBITORS OF BASE EXCISION REPAIR
(BER) IN CANCER The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major... |
| 2016/0102359 |
GENETIC MARKER FOR EARLY BREAST CANCER PROGNOSIS PREDICTION AND DIAGNOSIS,
AND USE THEREOF A gene for predicting or diagnosing the prognosis of early-stage breast cancer and to a use thereof is disclosed, and more specifically a genetic marker for... |
| 2016/0102358 |
METHODS AND COMPOSITIONS FOR CORRELATING GENETIC MARKERS WITH CANCER RISK The present invention provides methods of assessing an individual subject's risk of developing different types of cancer, comprising calculating a genetic risk... |
| 2016/0102357 |
NOVEL RUTHENIUM (II) COMPLEXES, PREPARATION AND USES THEREOF The present invention discloses novel Ruthenium (II) polypyridyl complexes, preparation and its application as DNA imaging agents. |
| 2016/0102356 |
ALLELIC DISORDERS CAUSED BY MUTATIONS IN TRPV4 The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4... |
| 2016/0102355 |
THROMBOEMBOLIC DISEASE MARKERS The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention... |
| 2016/0102354 |
Systems For Biomarker Detection Biomarker associated with Alzheimer's Disease (AD) and/or Mild Cognitive Impairment (MCI), where the biomarker is an intracellular or circulating microRNA... |
| 2016/0102353 |
Polymorphisms Associated With Age-Related Macular Degeneration and Methods
for Evaluating Patient Risk The present invention provides for certain polynucleotide sequences that have been correlated to AMD. These polynucleotides are useful as diagnostics, and are... |
| 2016/0102352 |
COMPOSITIONS CONTAINING IDENTIFIER SEQUENCES ON SOLID SUPPORTS FOR NUCLEIC
ACID SEQUENCE ANALYSIS Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing... |
| 2016/0102351 |
Flow Cell Array and Uses Thereof Apparatus and methods for using a flow cell array are provided herein. A method includes delivering multiple items of chemical matter independently to multiple... |
| 2016/0102350 |
Flow Cell Array and Uses Thereof Apparatus and methods for using a flow cell array are provided herein. A method includes determining placement of multiple reaction site openings, wherein each... |
| 2016/0102349 |
METHODS FOR SEQUENCING POLYNUCLEOTIDES The invention relates to methods and systems for sequencing and constructing a high resolution physical map of a polynucleotide. In accordance with the... |
| 2016/0102348 |
METHODS, SYSTEMS, AND COMPUTER-READABLE MEDIA FOR ACCELERATED BASE CALLING Embodiments disclose methods, systems, and computer-readable media for accelerated base calling of sequencing data. These methods may be adapted to accelerate... |
| 2016/0102347 |
METHODS FOR HIGH LEVEL MULTIPLEXED POLYMERASE CHAIN REACTIONS AND
HOMOGENEOUS MASS EXTENSION REACTIONS Provided herein are optimized methods for performing multiplexed detection of a plurality of sequence variations. Also provided are methods for performing... |
| 2016/0102346 |
MULTIPLEXED DIGITAL ASSAY WITH SPECIFIC AND GENERIC REPORTERS Digital assay system, including methods, apparatus, and compositions, for performing target assays in partitions each containing a generic reporter and a... |
| 2016/0102345 |
Sequence Conversion and Signal Amplifier DNA Having Poly DNA Spacer
Sequences and Detection Methods Using Same Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an... |
| 2016/0102344 |
Site-Specific Immobilization of DNA Origami Structures on Solid Substrates The present invention relates to methods for the site-specific immobilization of DNA origami structures on solid substrates, as well as to respective... |
| 2016/0102343 |
STRAND-INVASION BASED DNA AMPLIFICATION METHOD A method for detecting toxigenic Clostridium difficile (C. difficile) by strand-invasion based DNA amplification is provided, together with oligonucleotides,... |
| 2016/0102342 |
System and Method for Rapid Detection and Identification of Nucleic Acid
Labeled Tags A system for identifying which of a plurality of nucleic acid tag varieties are present on an item of interest. The system includes nucleic acid tag varieties... |
| 2016/0102341 |
BIOMOLECULE ISOLATION AND THERMAL PROCESSING Methods, devices and systems for hand-tag sample liquids, encapsulating liquids and magnetic particles are disclosed. |
| 2016/0102340 |
METHODS FOR PREPARATION OF NUCLEIC ACID-CONTAINING SAMPLES USING CLAY
MINERALS AND ALKALINE SOLUTIONS The present invention provides a rapid and highly effective method for the preparation of biological samples for detection of both DNA and RNA target... |
| 2016/0102339 |
Sequence Conversion and Signal Amplifier DNA Having Locked Nucleic Acids
and Detection Methods Using Same Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an... |
| 2016/0102338 |
BIOLUMINESCENT SUCCINATE DETECTION ASSAY Provided herein are methods for detecting and quantifying succinate in a sample. Also provided are methods for detecting and quantifying 2-oxoglutarate... |
| 2016/0102337 |
GLUTAMATE OXIDASE MUTAGENESIS FOR DIAGNOSTIC TESTING The described invention provides a method for detecting a target analyte that exhibits protease enzyme activity. The described method includes contacting a... |
| 2016/0102336 |
FLUORESCENT PROBE FOR DETECTING ACTIVITY OF CALPAIN [Problem] To provide a novel fluorescent probe for detecting the activity of calpain. [Solution] A compound represented by general formula (I) or a salt thereof. |
| 2016/0102335 |
BIOLOGICAL INDICATOR This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene... |
| 2016/0102334 |
RAPID ANTIMICROBIAL SUSCEPTIBILITY TEST, BASED ON AN ANALYSIS OF CHANGES
IN MORPHOLOGY AND GROWTH PATTERN OF A... Provided are a rapid antimicrobial susceptibility test, based on an analysis of changes in morphology and growth pattern of a microbial cell under different... |
| 2016/0102333 |
QUANTITATIVE CONTROL OF SIALYLATION AND SPECIFIC MONO-SIALYLATION The present disclosure is directed to the use of certain glycosyltransferase variants having N-terminal truncation deletions. It was found that the combination... |
| 2016/0102332 |
METHODS FOR MAKING TARGETED PROTEIN TOXINS BY SORTASE-MEDIATED PROTEIN
LIGATION We described novel methods for making targeted protein toxins by sortase-mediated protein ligation. The methods allow for a toxin and receptor-binding ligand... |
| 2016/0102331 |
EXTRACELLULAR DITERPENE PRODUCTION The present invention relates to a method for the production of a diterpene or a glycosylated diterpene, which method comprises: a. fermenting a recombinant... |
| 2016/0102330 |
PRODUCTION OF DIRHAMNOSE-LIPID IN RECOMBINANT NONPATHOGENIC BACTERIUM
PSEUDOMONAS CHLORORAPHIS Pseudomonas chlororaphis NRRL B-30761 produces monorhamnolipids with predominantly 3-hydroxydodecenoyl-3-hydroxydecanoate (C.sub.12:1-C.sub.10) or... |
| 2016/0102329 |
ACOUSTIC ENERGY MEDIATION OF GENETIC FRAGMENTATION Method and apparatus for controlling acoustic treatment of a sample to mediate a tagmentation process used on double stranded DNA. |
| 2016/0102328 |
Microalgae Aurantiochytrium sp. LA3 (KCTC12685BP) and Method for Preparing
Bio-Oil Using the Same Provided herein are microalgae of a Thraustochytrid and a method for preparing bio-oil using the same, and more particularly, Aurantiochytrium sp. LA3... |
| 2016/0102327 |
METHODS AND COMPOSITIONS FOR PRODUCING FATTY ALCOHOLS Methods and compositions, including nucleotide sequences, amino acid sequences, and host cells, for producing fatty alcohols are described. |
| 2016/0102326 |
METHOD FOR PRODUCING POLY-3-HYDROXYALKANOIC ACID AND AGGLOMERATES THEREOF When industrially separating and purifying poly-3-hydroxyalkanoic acid produced by a microorganism, to obtain poly-3-hydroxyalkanoic acid agglomerates having... |
| 2016/0102325 |
Method for Storing Gaseous Hydrogen Through Producing Methanoate (Formate) The present invention relates to a method for storing gaseous hydrogen, comprising the steps of producing methanoate (formate) through contacting gaseous... |
| 2016/0102324 |
NEW COMPACT SCAFFOLD OF CAS9 IN THE TYPE II CRISPR SYSTEM The present invention is in the field of CRISPR-Cas system for genome targeting. The present invention relates to new engineered Cas9 scaffolds and uses... |
| 2016/0102323 |
A LAGLIDADG HOMING ENDONUCLEASE CLEAVING THE C-C CHEMOKINE RECEPTOR TYPE-5
(CCR5) GENE AND USES THEREOF Disclosed herein are compositions for inactivating the human CCR5 gene comprising engineered LAGLIDADG homing endonucleases (LHEs) and their derivatives,... |
| 2016/0102322 |
CRISPR OLIGONUCLEOTIDES AND GENE EDITING The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR... |
| 2016/0102321 |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN
TRANSLATION The present invention provides novel mRNA elements capable of forming hairpin, double-stranded RNA structures independent of other non-coding RNAs. These mRNAs... |
| 2016/0102320 |
ADENOVIRAL VECTOR ENCODING HUMAN ATONAL HOMOLOG-1 (HATH1) The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein... |
| 2016/0102319 |
CMP-ACETYLNEURAMINIC ACID HYDROXYLASE TARGETING VECTOR, TRANSGENIC ANIMAL
FOR XENOTRANSPLANTATION INTRODUCED... There is provided a CMP-acetylneuraminic acid hydroxylase targeting vector, a transgenic animal for xenotransplantation introduced with the vector, and a... |
| 2016/0102318 |
MELON PLANTS WITH IMPROVED DISEASE TOLERANCE The present disclosure provides melon plants exhibiting tolerance to cucurbit yellow stunt disorder virus (CYSDV) and lacking negative traits associated with... |
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