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Patent # Description
2016/0102117 METHODS FOR TREATMENT OF INFLAMMATORY CONDITIONS USING S-[4-(3- FLUORO-3-METHYLBUTYRYLOXY) BUT-2-YNYL] 6ALPHA, ...
The present invention relates to methods of treatment of inflammatory conditions using ...
2016/0102116 HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
Glycosphingolipids (GSLs) compositions and methods for iNKT-independent induction of chemokines are disclosed.
2016/0102115 NOVEL METHOD FOR SYNTHESIZING N-ALKYL-GLYCOSYL(DI)AMINE DERIVATIVES AND USES OF SAME AGAINST PHYTOPATHOGENS
The present invention relates to a novel method for synthesising, without a solvent, N-alkyl-glycosyl(di)amine derivatives represented by the following general...
2016/0102114 METHOD FOR PREPARING LOW-MOLECULAR LIGNIN DERIVATIVE
A method of preparing a low-molecular lignin derivative comprises the step of: preparing lignin by hydrolyzing lignocellulosic biomass with an acid; preparing...
2016/0102113 METHODS FOR PREPARING THERMALLY STABLE LIGNIN FRACTIONS
The present invention relates to fractions of high purity lignin which are thermally stable, and to methods of producing said fractions from lignocellulosic...
2016/0102112 DINITROSYL IRON COMPLEXES, USES THEREOF, AND WATER SPLITTING DEVICE USING THE SAME
Dinitrosyl iron complexes are disclosed, which are represented by the following formula (I): ...
2016/0102111 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD
A method for producing a cyclic aminoorganoxysilane compound is provided. The method comprises the step of conducting dehydrochlorination coupling of a...
2016/0102110 HYDROXYSILANE AND POLYMER CONTAINING SILANE GROUPS
Special hydroxysilanes, which can be obtained by reacting .beta.-(3,4-epoxycyclohexyl)alkyltrialkoxysilanes with secondary amines, and adducts of the...
2016/0102109 HYDROPHOBIC INORGANIC PARTICLES, RESIN COMPOSITION FOR HEAT DISSIPATION MEMBER, AND ELECTRONIC COMPONENT DEVICE
Disclosed are hydrophobic inorganic particles obtained by surface-modifying inorganic particles with an organic compound, in which the organic compounds are...
2016/0102108 TUNABLE RARE-EARTH FCU-METAL-ORGANIC FRAMEWORKS
Metal organic framework compositions can have a face centered cubic structure.
2016/0102107 PYRAZOLO-PYRROLIDIN-4-ONE DERIVATIVES AS BET INHIBITORS AND THEIR USE IN THE TREATMENT OF DISEASE
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the...
2016/0102106 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF
Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one...
2016/0102105 BACE1 INHIBITORS
The present invention provides a compound of formula I, having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and...
2016/0102104 Ataxia Telengiectasia And Rad3-Related (ATR) Protein Kinase Inhibitors
A macrocyclic compound having the structure of Formula (A), wherein each of R.sup.1 and R.sup.2 is independently (i) a 5-6 membered monocyclic aromatic ring...
2016/0102103 SUBSTITUTED PYRIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY
The present invention provides a substituted pyridine compound of the formula I ##STR00001## or an agriculturally suitable salt or N-oxide thereof, wherein the ...
2016/0102102 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS
This disclosure relates to novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities. A tricyclic heterocyclic...
2016/0102101 Preparation method of Ticagrelor and intermediates thereof
Disclosed in the present invention is a method for preparing Ticagrelor (I), comprising the following steps: a cyclization reaction of ...
2016/0102100 FUSED HETEROCYCLIC COMPOUND
The fused heterocyclic compound represented by formula (1) has excellent effectiveness in pest control. ##STR00001## In the formula (1), J represents formula J1,...
2016/0102099 ANTI-VIRAL COMPOUNDS
Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate...
2016/0102098 BISULFATE OF JANUS KINASE (JAK) INHIBITOR AND PREPARATION METHOD THEREFOR
The present invention relates to a bisulfate of a Janus kinase (JAK) inhibitor and a preparation method therefor. More specifically, the present invention...
2016/0102097 COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT
Compounds and compositions useful for treating disorders related to mutant KIT are described herein.
2016/0102096 COMPOUNDS AND METHODS FOR INHIBITING HISTONE DEMETHYLASES
The present application relates to compounds being of Formula (I), (II), (III), (IV), (V), (VI), (IIIa), (IIIb), (IIIc), (IIId), (IIIe), (IIIf), and (IIIg)....
2016/0102095 PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVE AND USE OF ANTI-TUMOR THEREOF
The present invention relates to a pyrazolo[1,5-a]pyrimidine derivative of general formula 1 and a pharmaceutically acceptable salt thereof. The present...
2016/0102094 Azaquinazoline Inhibitors of Atypical Protein Kinase C
The present application provides a compound of formula (1) ##STR00001## or a salt thereof, wherein R.sup.7, R.sup.8, R.sup.9, G, and X are as defined herein....
2016/0102093 CO-PROCESSING METHOD AND FORMULATION FOR HIV ATTACHMENT INHIBITOR PRODRUG COMPOUND AND EXCIPIENTS
A process for the production of a formulation of HIV attachment inhibitor piperazine tris salt prodrug compound involves dissolving the prodrug compound in a...
2016/0102092 Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; ##STR00001## a method for manufacturing said compound,...
2016/0102091 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid...
2016/0102090 SUBSTITUTED 3-BENZYLQUINOXALIN-4(3H)-ONE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYCHOLINE...
In one aspect, the invention relates to 3-benzylquinazolin-4(3H)-one analogs compounds, derivatives thereof, and related compounds, which are useful as...
2016/0102089 Arylpyrrolopyridine derived compounds as LRRK2 inhibitors
The present invention is directed to arylpyrrolopyridine derivatives of formula (A) (A). The compounds are considered useful for the treatment of diseases...
2016/0102088 PIPERIDYLPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASE INHIBITORS AND OF VASCULAR ENDOTHELIAL GROWTH...
This invention is directed to a compound of Formula I ##STR00001## or a pharmaceutically acceptable salt thereof, wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4,...
2016/0102087 COMPOUNDS AND METHODS FOR THE TREATMENT OF ISOCITRATE DEHYDROGENASE RELATED DISEASES
The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof: ##STR00001##
2016/0102086 NOVEL FORMULATION OF MELOXICAM
The present invention relates to methods for producing particles of meloxicam using dry milling processes as well as compositions comprising meloxicam,...
2016/0102085 NOVEL (CYANO-DIMETHYL-METHYL)-ISOXAZOLES AND -[1,3,4]THIADIAZOLES
This invention relates to novel (Cyano-dimethyl-methyl)-isoxazolesand-[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical...
2016/0102084 COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY
The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which...
2016/0102083 ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions...
2016/0102082 TARTRATE SALT OF 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ...
The invention relates to the tartrate salt of 5-chloro-thiophene-2-carboxylic acid [(S)-2-[methyl-3-(2-oxo-pyrrolidin-1-yl) ...
2016/0102081 Heterocycle-substituted Pyridyl Benzothiophenes as Kinase Inhibitors
This invention is directed to a compound of Formula I ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and...
2016/0102080 PYRIDYL BENZOTHIOPHENES AS KINASE INHIBITORS
This invention is directed to compounds, which are useful as protein kinase (PK) inhibitors and can be used to treat such diseases as cancer, blood vessel...
2016/0102079 ACETONE SOLVATE CRYSTALS OF TRITYL OMESARTAN MEDOXOMIL
Acetone solvate crystals of trityl olmesartan medoxomil are provided.
2016/0102078 NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME
The present invention relates to (E)-ethyl 2-(2-methyl-3-((2-(naphtho[2,1-b]furan-2-carbonyl)hydrazono)methyl)-1H-in- dol-1-yl)acetate as a novel tubulin...
2016/0102077 Indole-3-Carboxamides as Kinase Inhibitors
This invention is directed to a compound of Formula I ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4,...
2016/0102076 COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES
The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are...
2016/0102075 UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS
Unsaturated nitrogen heterocyclic compounds of formula (I): ##STR00001## as defined in the specification, compositions containing them, and processes for...
2016/0102074 SUBSTITUTED AMIDE COMPOUNDS
The present invention is directed at substituted amide compounds, pharmaceutical compositions containing such compounds and the use of such compounds to reduce...
2016/0102073 2-HYDROXYMETHYL-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS
The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the...
2016/0102072 FUNGICIDAL COMPOSITIONS
The instant invention describes tetrazole compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof...
2016/0102071 SUBSTITUTED BENZOTHIOPHENYL DERIVATIVES AS GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are...
2016/0102070 ANHYDROUS CRYSTALLINE FORM OF S-EQUOL
An anhydrous crystalline form of S-equol has been discovered. Form I, the anhydrous crystalline form of S-equol has been isolated and characterized for the...
2016/0102069 ANTIOXIDANT HUMIC ACID DERIVATIVES AND METHODS OF PREPARATION AND USE
Disclosed are antioxidative, natural compounds, their salts, chelates and cleavage derivatives that exhibit a superior combination of properties. The compounds...
2016/0102068 SUCCINIC ANHYDRIDE FROM ETHYLENE OXIDE
Continuous flow systems and methods produce succinic anhydride by a double carbonylation of ethylene oxide with carbon monoxide and at least one catalyst. In...
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