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Patent # Description
2016/0108082 Preparation and Uses of Obeticholic Acid
The present invention relates to obeticholic acid: ##STR00001## or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid...
2016/0108081 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF
The present invention relates to the synthesis of ent-progesterone and intermediates thereof.
2016/0108080 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I), and pharmaceutically acceptable salts thereof; wherein-, R.sup.1, R.sup.2,...
2016/0108079 Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization
Methods for preparation of 2',3'-dideoxynucleotides support structures, such as 2',3'-dideoxyguanosine, 2',3'-dideoxyadenosine, and 3'-deoxythymidine support...
2016/0108078 GLUCOPYRANOSIDE COMPOUND
A compound of the formula: ##STR00001## wherein Ring A and Ring B are: (1) Ring A is an optionally substituted unsaturated monocyclic heterocyclic ring, and Ring...
2016/0108077 TYLOSIN DERIVATIVES AND METHOD FOR PREPARATION THEREOF
The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (IIa), a pharmaceutical or veterinary...
2016/0108076 MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES
The invention concerns compounds of the formula (I) wherein: Y.sup.1 and Y.sup.2 are independently a monosaccharide or disaccharide; X.sup.1 and X.sup.2 are...
2016/0108075 Process for producing a particulate composition comprising crystalline trehalose dihydrate
A process for enabling the production of a particulate composition containing crystalline trehalose dihydrate is provided. Including allowing an...
2016/0108074 SOLID ACID CATALYST FOR PREPARING A MONOSACCHARIDE AND METHOD OF PREPARING A MONOSACCHARIDE FROM SEAWEED USING...
A solid acid catalyst for preparing a monosaccharide by degrading agarose includes a particle having a carbonized chaff and a sulfonyl group which is...
2016/0108073 NOVEL TRANSITION METAL COMPLEXES, THEIR PREPARATION AND USE
Novel transition metal complexes are provided which represent viable catalysts for a broad variety of reactions such as hydrogenation reactions and metathesis...
2016/0108072 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT
An electrochromic compound, represented by the following general formula (I); ##STR00001## where X.sub.1 to X.sub.4 are each a substituent represented by the ...
2016/0108071 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS
The present invention provides a method for easily and inexpensively producing a heterogeneous catalyst used to synthesize a cyclic carbonate by reacting an...
2016/0108070 NON-AQUEOUS ELECTROLYTE SOLUTION FOR BATTERY, NOVEL COMPOUND, POLYELECTROLYTE, AND LITHIUM SECONDARY BATTERY
A non-aqueous electrolyte solution for a battery, including a compound represented by formula (1), wherein each A represents P or P.dbd.O; each R represents H,...
2016/0108069 DINUCLEAR METALLOCENE COMPOUND, AND A METHOD FOR PREPARING THE SAME
The present invention relates to a dinuclear metallocene compound with a new structure which can manufacture polyolefin having high molecular weight and to a...
2016/0108068 METHOD FOR THE PRODUCTION OF A TITANIUM CONTAINING CATALYST, TITANIUM CONTAINING CATALYST, METHOD FOR THE...
The present invention is directed to a method for the production of a titanium containing catalyst, wherein a titanium-(IV)-alkoxide of high purity is reacted...
2016/0108067 Method for Producing Fluorine-Containing Substituted Compound and Fluorine-Containing Substituted Compound
A method for producing a fluorine-containing substituted compound, the method including: introducing an organofluorine compound and an organolithium compound...
2016/0108066 SILICONE COMPOUND HAVING A RADICAL-POLYMERIZABLE GROUP AND A METHOD FOR THE PREPARATION THEREOF
The present invention provides a radical-polymerizable group-containing silicone compound which is liquid at room temperature and has good handling properties,...
2016/0108065 Branched Oligoarylsilanes and Method for Producing Same
Novel branched oligoarylsilanes of general formula (I) ##STR00001## A method of preparation of branched oligoarylsilanes is that a compound of general formula...
2016/0108064 AMINO(BROMO)SILANE PRECURSORS FOR ALD/CVD SILICON-CONTAINING FILM APPLICATIONS AND METHODS OF USING THE SAME
Disclosed are Si-containing film forming compositions, methods of synthesizing the same, and methods of using the same to deposit silicon-containing films...
2016/0108063 BORON-CONTAINING SMALL MOLECULES
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal...
2016/0108062 NOVEL TETRAARYL BORATE COMPOUND AND METHOD FOR PRODUCING SAME
The present invention relates to a novel tetraaryl borate compound and a method for producing the same, and a method for producing a tetraaryl borate compound...
2016/0108061 ACC INHIBITORS AND USES THEREOF
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same....
2016/0108060 ACC INHIBITORS AND USES THEREOF
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
2016/0108059 FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS
The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein ...
2016/0108058 An improved process for the preparation of Dolutegravir
The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention...
2016/0108057 TRICYCLIC HETEROCYCLIC COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE INHIBITORS
Compounds of formula (I) or a pharmaceutically acceptable sail thereof, wherein: W is O, N--H, N--(C.sub.1-C.sub.10 alkyl) or S; each X is independently CH or...
2016/0108056 HETEROCYCLIC DERIVATIVES AND USE THEREOF
A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the...
2016/0108055 POLYMORPHIC FORMS OF ICOTINIB AND USES THEREOF
The present invention relates to the polymorphic forms of the compound of Formula I, preparation thereof and pharmaceutical compositions, and use of a...
2016/0108054 Lactam Kinase Inhibitors
Compounds useful as kinase inhibitors are provided herein, as well as salts, pharmaceutical compositions, methods of medical treatment and methods of synthesis...
2016/0108053 PROCESSES FOR MAKING PONATINIB AND INTERMEDIATES THEREOF
Novel synthetic approaches to make 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin- -1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide,...
2016/0108052 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY
The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid .beta. protein, for...
2016/0108051 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASE
The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent...
2016/0108050 IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS
The invention provides compounds of Formula (I) ##STR00001## and pharmaceutically acceptable salts thereof. The Formula (I) imidazotriazines inhibit protein...
2016/0108049 Novel Phthalazinone-Pyrrolopyrimidinecarboxamide Derivatives
The compounds of formula (1), in which R1, R7, R8, R9, R10, R17, R18, R19, R20 and m have the meanings as given in the description, are novel effective...
2016/0108048 IMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG
The present invention relates to Imidazole Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein A, B, Y, R.sup.1 and R.sup.2 are...
2016/0108047 IMIDAZOPYRROLIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the...
2016/0108046 INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic...
2016/0108045 SOLID FORMS OF A TOLL-LIKE RECEPTOR MODULATOR
The present invention provides crystalline forms, solvates and hydrates of 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropterid- in-6(5H)-one,...
2016/0108044 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES AND CARDIOMYOPATHY
Disclosed herein inter alia are compositions and methods useful in the treatment neurodegenerative diseases and cardiomyopathy, and for modulating the activity...
2016/0108043 NORIBOGAINE SALT ANSOLVATES
Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can...
2016/0108042 INDOLIZINO[3,2-c]QUINOLINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF...
Provided are an indolizino[3,2-c]quinoline derivative, pharmaceutically acceptable salt thereof, and a method for preparing the same. The ...
2016/0108041 SUBSTITUTED PYRIDINONE COMPOUNDS AS MEK INHIBITORS
The invention provides novel substituted heterocyclic compounds represented by Formula I and Formula II, or a pharmaceutically acceptable salt, solvate,...
2016/0108040 DERIVATIVES OF [1, 2, 4] TRIAZOLO [4, 3 - A] PYRIDINE AS P38 - MAP KINASE INHIBITORS
This invention relates to compounds selected in the group consisting of compounds of formula (Ia) to (Id) and compositions, that are p38 MAPK inhibitors,...
2016/0108039 TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES
The invention relates to substituted triazolopyridines and to processes for their preparation and to their use for preparing medicaments for the treatment...
2016/0108038 BICYCLIC ARYL SULFIDE AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENT
The present application relates to novel heterocyclic compounds, to processes for their preparation, to their use for controlling animal pests including...
2016/0108037 HETEROCYCLIC AMIDE COMPOUND
The present invention provides a heterocyclic amide compound of Formula (1), and an agricultural chemical containing it, particularly a herbicide: ...
2016/0108036 HETEROCYCLIC DERIVATES
The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the...
2016/0108035 CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF
Cycloalkyl acid derivatives, a preparation method thereof, and a pharmaceutical application thereof are described. In particular, a cycloalkyl acid derivative...
2016/0108034 NAPHTHYRIDINE DERIVATIVE COMPOUNDS
The invention relates to new naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of...
2016/0108033 HISTONE DEMETHYLASE INHIBITORS
The present invention relates generally to compositions and methods for treating cancer and neoplastic diseases. Provided herein are substituted ...
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