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Patent # Description
2016/0108432 DROPLET ACTUATOR FOR ELECTROPORATION AND TRANSFORMING CELLS
The invention provides a droplet actuator designed for performing electroporation on cells in droplets. The invention also provides method and systems for...
2016/0108431 PREVENTION AND TREATMENT OF ATRIAL FIBRILLATION
There is provided a nucleic acid that inhibits miR-31 in an atrial myocyte, for use in the prevention or treatment of atrial fibrillation in a subject. Also...
2016/0108430 GENE-THERAPY VECTORS FOR TREATING CARDIOMYOPATHY
The present invention relates to a gene therapy vector which is useful in the treatment or prevention of hypertrophic cardiomyopathy in a subject in need...
2016/0108429 PEG-PROM MEDIATED SURFACE EXPRESSION OF AVIDIN/STREPTAVIDIN
The presently disclosed subject matter relates to compositions and methods directed to cancer theranostic nucleic acid constructs that permit simultaneous...
2016/0108428 Novel Chimeric Insecticidal Proteins Toxic or Inhibitory to Lepidopteran Pests
Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide...
2016/0108427 Proteins Toxic or Inhibitory to Lepidopteran Insects
Nucleotide sequences are disclosed encoding novel, insecticidal TIC2160 and TIC3244 proteins, and variants thereof, and related proteins exhibiting...
2016/0108426 Lepidopteran-Active Cry1Da1 Amino Acid Sequence Variant Proteins
Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to...
2016/0108425 COMPOSITIONS AND METHODS FOR INSECTICIDAL CONTROL OF STINKBUGS
Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the...
2016/0108424 METHOD FOR INCREASING PATHOGEN RESISTANCE IN PLANTS
The invention relates to a method of increasing the resistance to one or more pathogens, preferably fungal or bacterial pathogens, in a monocotyledonous or...
2016/0108423 HERBICIDE-TOLERANT PLANTS
The present invention provides herbicide-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an...
2016/0108422 HERBICIDE TOLERANCE GENES AND METHODS OF USE THEREOF
Polypeptides and recombinant DNA molecules useful for conferring tolerance to AOPP herbicides, phenoxy acid herbicides, and pyridinyloxy acid herbicides are...
2016/0108421 METHOD FOR PRODUCING STRESS TOLERANT TRANSGENIC PLANT BY SILENCING A GENE ENCODING CALCIUM-DEPENDENT...
A method for silencing rice plant, includes the steps of: identifying a first nucleotide sequence from Oryza sativa, wherein the first nucleotide sequence is...
2016/0108420 PLANTS HAVING INCREASED DESICCATION TOLERANCE, INCREASED DROUGHT TOLERANCE OR INCREASED WATER USE EFFICIENCY
A transgenic plant engineered to have increased desiccation tolerance, increased drought tolerance or increased water use efficiency, the plant transformed...
2016/0108419 PLANTS HAVING ONE OR MORE ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME
A method for enhancing various economically important yield-related traits in plants is provided. More specifically, a method for enhancing one or more...
2016/0108418 PLANT WITH REDUCED PROTEIN PRODUCTIVITY IN SEEDS AND METHOD FOR PRODUCING SAME
According to the present invention, a gene having a novel function that can cause an increase or decrease in seed protein content is searched for. A chimeric...
2016/0108417 PLANT WITH REDUCED PROTEIN PRODUCTIVITY IN SEEDS AND METHOD FOR PRODUCING SAME
According to the present invention, a gene having a novel function that can cause an increase or decrease in seed protein content is searched for. A chimeric...
2016/0108416 ATSP1, AN E3 UBIQUITIN LIGASE, AND ITS USE
The invention relates to plants with improved phenotypes and related methods. These improved phenotypes are conferred by altering the expression of the SP1...
2016/0108415 MANIPULATION OF GLUTAMINE SYMTHETASES (GS) TO IMPROVE NITROGEN USE EFFICIENCY AND GRAIN YIELD IN HIGHER PLANTS
The present invention provides polynucleotides and related polypeptides of the protein GS. The invention provides genomic sequence for the GS gene. GS is...
2016/0108414 GROWTH-RELATED ENOX PROTEINS FROM PLANTS WITH YIELD ENHANCEMENT POTENTIAL, SEQUENCES AND METHODS
Described are compositions of matter and methods useful for increasing the yield of transgenic agricultural crops. Sequence information of ENOX proteins and...
2016/0108413 ENHANCED SELECTIVE EXPRESSION OF TRANSGENES IN FIBER PRODUCING PLANTS
Methods and means are provided to enhance the selective expression of transgenes under control of a fiber-selective promoter, in fiber cells, particularly...
2016/0108412 Modified FRT Recombination Site Libraries and Methods of Use
Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination...
2016/0108411 METHODS AND COMPOSITIONS FOR TRANSGENIC PLANTS WITH ENHANCED COLD TOLERANCE, ABILITY TO FLOWER WITHOUT...
The present invention provides transgenic plants having increased tolerance to cold and altered flowering characteristics. Also provided are methods and...
2016/0108410 MODULAR SYNTHETIC GAL1 PROMOTER AND USE THEREOF
The present invention relates to a nucleic acid molecule that comprises at least one synthetic GAL1 core promoter containing one or more ligand responsive...
2016/0108409 Method for improved protein production in filamentous fungi
The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a...
2016/0108408 METHOD FOR DIRECTIONAL CLONING
Described herein are techniques for directional cloning an insert DNA segments into a target vector. The techniques mix the target vector, the insert DNA...
2016/0108407 IMPROVED SURFACE DISPLAY OF FUNCTIONAL PROTEINS IN A BROAD RANGE OF GRAM NEGATIVE BACTERIA
The present invention relates to a method for the surface display of a recombinant polypeptide on the surface of a host cell, said method comprising the steps:...
2016/0108406 METHOD OF REGULATING CFTR EXPRESSION AND PROCESSING
The present invention relates to methods of reducing .DELTA.F508-CFTR ubiquitination or degradation, or increasing .DELTA.F508-CFTR processing or function in a...
2016/0108405 LUNG CANCER DIAGNOSTICS AND THERAPEUTICS WITH MIR-660
Provided are methods of treating lung cancer in a patient in need thereof. The method includes administration to the patient a composition comprising a...
2016/0108404 Method for Inhibiting HIV Replication in Mammal and Human Cells
The present invention describes a method to inhibit replication of the human immunodeficiency virus (HIV) by negatively modulating or altering the...
2016/0108403 NUCLEIC ACID APTAMERS
The present invention relates to optimized aptamers and methods of using these aptamers.
2016/0108402 METHODS FOR DIAGNOSING AND TREATING LEARNING OR MENTAL DISORDERS
The present invention embraces methods for the diagnosis and treatment of learning or mental disorders such as schizophrenia using miR-25, miR-98, or miR-185.
2016/0108401 COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using...
2016/0108400 Single-Stranded Nucleic Acid Molecule for Controlling Gene Expression
Provided is a novel nucleic acid molecule that is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression...
2016/0108399 MODULATION OF HSP47 EXPRESSION
Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions,...
2016/0108398 Hydrophobically Modified Antisense Oligonucleotides Comprising a Ketal Group
The present invention concerns an oligonucleotide modified by substitution at the 3' or the 5' end by a moiety comprising at least one ketal functional group,...
2016/0108397 TARGETING MICRORNAS FOR THE TREATMENT OF FIBROSIS
Provided herein are compositions and methods for the modulation of miR-214 for the treatment and/or prevention of fibrosis and fibroproliferative conditions.
2016/0108396 OLIGOMERS TARGETING HEXANUCLEOTIDE REPEAT EXPANSION IN HUMAN C9ORF72 GENE
The disclosure relates to oligomers capable of targeting RNA expressed from the human C9ORF72 gene containing a pathogenic hexanucleotide repeat expansion....
2016/0108395 CHIMERIC SINGLE-STRANDED ANTISENSE POLYNUCLEOTIDES AND DOUBLE-STRANDED ANTISENSE AGENT
Chimeric single-stranded polynucleotides and double-stranded antisense agents useful for modifying the expression of a target gene by means of an antisense...
2016/0108394 MOLECULAR IDENTITY TAGS AND USES THEREOF IN IDENTIFYING INTERMOLECULAR LIGATION PRODUCTS
Molecular identity tags and methods of marking target nucleic acids with molecular identity tags for identifying intermolecular ligation products. Terminal...
2016/0108393 Rapid Nucleic Acid Extraction Method and Apparatus
A syringe device having a plunger beneath which is disposed a rupturable capsule containing a nucleic acid wash buffer and a rupturing mechanism for rupturing...
2016/0108392 SOLID-CORE RING-MAGNET
A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either...
2016/0108391 REAGENT COMPOSITIONS HAVING PYRIDINE-CARBOXYLIC ACID-STABILIZED ENZYMES, AS WELL AS METHODS OF MAKING AND USING...
Dry reagent compositions are disclosed that include one or more of an enzyme such as a dehydrogenase, a redox cofactor, an agent capable of eliciting at least...
2016/0108390 COMPOSITION FOR STABILIZING EC-SOD AND METHOD OF STABILIZING EC-SOD USING THE SAME
The present invention relates to a composition for stabilizing extracellular superoxide dismutase (EC-SOD) protein and a method for stabilizing EC-SOD protein...
2016/0108389 HIGH POTENCY PANCREATIN PHARMACEUTICAL COMPOSITIONS
The present disclosure provides high potency pharmaceutical compositions comprising high activity pancreatin enzymes. The invention is also directed to a...
2016/0108388 NOVEL METALLOPROTEASES
Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods...
2016/0108387 NOVEL METALLOPROTEASES
Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods...
2016/0108386 CELLULOLYTIC ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase,...
2016/0108385 HYPERTHERMOSTABLE ENDOGLUCANASE BELONGING TO GH FAMILY 12
A hyperthermostable endoglucanase including an endoglucanase catalytic domain, the endoglucanase catalytic domain including: (A) a polypeptide including an...
2016/0108384 Amylases, Nucleic Acids Encoding Them and Methods for Making and Using Them
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and...
2016/0108383 HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these...
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