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Patent # Description
2016/0114040 Derivatized Hyperbranched Polyglycerols
Herein are provided derivatized hyperbranched polyglycerols ("dHPGs"). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with...
2016/0114039 TREATMENT OF POLYPOIDAL CHOROIDAL VASCULOPATHY
Methods for treatment of Polypoidal choroidal vasculopathy (PCV) of the AMD or non-AMD type and pharmaceutical compositions for the use therein are disclosed.
2016/0114038 SCALABLE, MASSIVELY PARALLEL PROCESS FOR MAKING MICRO-SCALE PARTICLES
A method of fabrication produces one or more functional microparticles using a parallel pore working piece. In one embodiment, the method forms a particle that...
2016/0114037 COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY
The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the...
2016/0114036 COMPOSITION FOR STABILIZING PROTEIN AND PHARMACEUTICAL FORMULATION COMPRISING THE SAME
The present invention relates to a composition for stabilizing TNF.alpha.-binding protein exhibiting physiological activity, and more specifically, to a...
2016/0114035 PAN-DR Binding Polypeptides and Uses Thereof
The present invention provides novel artificial oligopeptides capable of binding HLA Class II molecules encoded by several alleles. The oligopeptides include...
2016/0114034 COMPOSITIONS COMPRISING ISCOM PARTICLES AND LIVE MICRO-ORGANISMS
Iscom particles can be used as an adjuvant for preparing of an antigenic composition which comprises live micro-organisms and/or killed micro-organisms and/or...
2016/0114033 ALUMINUM COMPOUNDS FOR USE IN THERAPEUTICS AND VACCINES
The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm...
2016/0114032 BACTERIOPHAGE-POLYMER HYBRID
The invention provides a targeted bacteriophage-polymer complex comprising a recombinant targeted-bacteriophage and a cationic polymer. The complex has a net...
2016/0114031 RECOMBINANTLY PRODUCED ALLERGENS
Methods for producing an allergen composition, methods for in vitro diagnosis of type I allergy, and diagnostic kits for performing diagnosis employ Bos d 23k...
2016/0114030 Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Surface Antigen Protein And Vaccine...
Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surface antigen proteins, fragments and combinations thereof as well...
2016/0114029 PORCINE PSEUDORABIES VIRUS, VACCINE COMPOSITION AND PREPARATION METHOD AND USE THEREOF
Provided in the embodiments of the present invention is a vaccine composition including an immune amount of attenuated live vaccine, inactivated vaccine,...
2016/0114028 DNA MOTIF COMPOUNDS AND METHODS FOR INDUCING SPECIFIC ANTIBODIES AND CELLULAR IMMUNITY
The present invention relates to the field of applied immunotechnology and medicine. More specifically, it relates to DNA motif vaccine design, glyco-DNA motif...
2016/0114027 RECOMBINANT HCMV AND RHCMV VECTORS AND USES THEREOF
The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as...
2016/0114026 PAN-LYSSAVIRUS VACCINES AGAINST RABIES
Described herein are recombinant rabies viruses encoding rabies virus glycoprotein and at least one heterologous glycoprotein from another lyssavirus, such as...
2016/0114025 COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response...
2016/0114024 LACTIC ACID BACTERIUM, DRUG, FOOD OR DRINK, AND FEED WHICH CONTAIN THE LACTIC ACID BACTERIUM
The Lactobacillus paracasei MCC1849 (NITE BP-01633) strain, which has a high IL-12 production-promoting action, is used as an ingredient of a drug, food or...
2016/0114023 CANCER AND SKIN LESION TREATMENT
A method for treating or reducing the incidence of recurrence of cancer, benign tumors or HPV-associated lesions, including skin cancer, and particularly...
2016/0114022 THERAPIES, VACCINES, AND PREDICTIVE METHODS FOR FILOVIRUSES INCLUDING EBOLAVIRUS AND MARBURG VIRUS
The present invention provides therapies, vaccines, and predictive methods for Filoviruses, including Ebolaviruses and Marburg viruses, and provides compounds...
2016/0114021 NOVEL SURFACE EXPOSED HAEMOPHILUS INFLUENZA PROTEIN (PROTEIN E; pE)
The present invention relates to a surface exposed protein (protein E; pE), a virulence factor, which can be detected in Haemophilus influenzae, having an...
2016/0114020 Targets and compositions for use in decontamination, immunoprophylaxis, and post-exposure therapy against anthrax
The present invention relates to the decontamination of anthrax spores, prophylaxis and treatment of anthrax infections and, more particularly, to compounds...
2016/0114019 WT1 ANTIGEN PEPTIDE CONJUGATE VACCINE
A compound represented by the formula (1): ##STR00001## wherein X.sup.a and Y.sup.a are each a single bond and the like, cancer antigen peptide A is an MHC class...
2016/0114018 IMP-3 EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING THE SAME
Isolated IMP-3-derived epitope peptides having Th1 cell inducibility are disclosed herein. Such peptides can be recognized by MHC class II molecules and induce...
2016/0114017 INTERLEUKIN-13 RECEPTOR ALPHA 2 PEPTIDE-BASED BRAIN CANCER VACCINES
Provided herein are interleukin-13 receptor .alpha.2 peptide-based brain cancer vaccines and methods for treating and vaccinating against brain cancer...
2016/0114016 COMPOSITIONS AND METHODS COMPRISING GLYCYL-TRNA SYNTHETASES HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES
Isolated glycyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods...
2016/0114015 TREATMENT OF SOCIAL ANXIETY DISORDER, OBSESSIVE COMPULSIVE DISORDER AND PANIC DISORDER USING BOTULINUM TOXIN
Methods are disclosed for treating social anxiety disorder, obsessive compulsive disorder, and/or panic disorder in a subject. The methods include...
2016/0114014 Compositions and Methods for Topical Application and Transdermal Delivery of Botulinum Toxins
A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a...
2016/0114013 PHARMACEUTICAL COMPOSITION COMPRISING A BOTULINUM NEUROTOXIN AND USES THEREOF
The invention relates a pharmaceutical composition containing botulinum toxin and a mucopolysaccharide uses thereof with increased pharmacological activity and...
2016/0114012 ENZYME FORMULATION FOR USE AS FOOD SUPPLEMENT
The present document describes an enzyme formulation comprising an enzyme mixture comprising from about 5% to about 45% (wt/wt) of a fungal protease enzyme;...
2016/0114011 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA...
2016/0114010 METHODS FOR TREATING BLEEDING DISORDERS USING A PLATELET SUBPOPULATION
The present invention relates to a platelet subpopulation with high binding capacity to recombinant activated factor VII (rFVIIa), and its use for the...
2016/0114009 Proteases Able to Hydrolyze Gluten Peptides and Proteins at Acidic PH, from the Actinomycete Actinoallomurus
The invention relates to a new family of proteolytic enxymes having the ability to hydrolize at a pH between 3 and 8 gluten olygopeptides which are resistant...
2016/0114008 Methods for accelerating the healing of connective tissue injuries and disorders
The invention is directed to methods for accelerating the healing of connective tissue injuries and disorders. In particular, the invention is directed to...
2016/0114007 COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASE, COMPRISING, AS ACTIVE INGREDIENT, PINK1 PROTEIN OR...
The present invention relates to a composition for preventing or treating an autoimmune disease comprising, as an active ingredient, PINK1 protein or...
2016/0114006 COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES
This disclosure relates to compositions for use in treatment of a retinal degenerative disease, such as age related macular degeneration. The described...
2016/0114005 HYBRID PROTEIN THAT CONVERTS ARACHIDONIC ACID INTO PROSTACYCLIN
A recombinant 130-kDa protein is constructed by linking together human cyclooxygenase (COX) isoform-2 (COX-2) and prostacyclin synthase (PGIS), via a 10-20...
2016/0114004 ROLE OF A CLUSTER OF LONG NONCODING RNA TRANSCRIPTS IN PROTECTING THE HEART FROM PATHOLOGICAL HYPERTROPHY
Nucleic acids encoding modified myosin heavy-chain-associated RNA transcripts are provided. The modified myosin heavy-chain-associated RNA transcripts belongs...
2016/0114003 PHARMACEUTICAL COMPOSITIONS COMPRISING COLLAGEN AND SODIUM HYALURONATE
The present invention relates to pharmaceutical compositions comprising collagen and hyaluronic acid, and optionally containing silver. Said compositions may be in...
2016/0114002 COMPOSITIONS COMPRISING PLANT PROTEINS AND METHODS FOR PREVENTION OF METABOLIC AND CARDIOVASCULAR PATHOLOGIES...
A composition for oral administration in humans comprising at least one plant protein chosen from pea proteins, rice proteins or a mixture thereof, and: at...
2016/0114001 INSULIN VITAMIN D CONJUGATES
The invention provides non-hormonal vitamin D conjugated to insulin peptides that result in the peptides having increased absorption, bioavailability or...
2016/0114000 CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS
Described are peptide analogs of glucagon, which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to...
2016/0113999 Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Prophylaxis of Heart Failure
The invention relates to treatment of heart failure in a mammal. Accordingly, the invention is directed to establishing a dosing regimen whereby the...
2016/0113998 Methods for Treating Congestive Heart Failure
The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like...
2016/0113997 BETA-CASEIN A2 AND PREVENTION OF INFLAMMATION OF THE BOWEL
The use of a composition for preventing or reducing the risk of inflammation of the bowel in an animal, wherein the composition contains beta-casein and...
2016/0113996 TAFA4 COMPOUNDS AND USES THEREOF FOR TREATING PAIN
The present invention relates to novel compounds for use for preventing, alleviating or treating pain in a subject. Also herein described are pharmaceutical...
2016/0113995 LIPID NANOPARTICLE OF POLYMYXIN
A lipid nanoparticle that includes at least one antibiotic from the polymyxin family, a lipid fraction, and one or more surfactants. The lipid nanoparticle is...
2016/0113994 METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated...
2016/0113993 THERAPEUTIC VITAMIN D CONJUGATES
The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when...
2016/0113992 COMBINATIONS OF EXTRACTS OF SERENOA REPENS AND LIPOPHILIC EXTRACTS OF ZINGIBER OFFICINALIS AND ECHINACEA...
Disclosed are compositions containing an extract of Serenoa repens, a lipophilic extract of Zingiber officinalis and a lipophilic extract of Echinacea...
2016/0113991 Aqueous Solution Formulated to Raise Body Temperature
An aqueous solution that is useful for helping to increase body temperature in people with chronic low body temperature, as well as people who suffer from cold...
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