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Patent # Description
2016/0120958 MARKER FOR ACID SPHINGOMYELINASE DISORDERS AND USES THEREOF
The present disclosure provides methods of screening, diagnosing, monitoring and/or treating acid sphingomyelinase (ASM) disorders such as Niemann-Pick...
2016/0120957 DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINGOMYELINASE DEFICIENCY
The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid...
2016/0120956 COMPOSITION OF ERYTHROCYTES ENCAPSULATING PHENYLALANINE HYDROXYLASE AND THERAPEUTIC USE THEREOF
The present invention relates to Enzyme Replacement Therapy (ERT) based on phenylalanine hydroxylase (PAH) and compositions intended for this use. It concerns...
2016/0120955 COMPOSITIONS COMPRISING COLLAGEN AND PRP FOR TISSUE REGENERATION
A composition of matter is disclosed which comprises crosslinked collagen, platelet rich plasma (PRP) and an inorganic salt. Methods of generating same and...
2016/0120954 Pharmaceutical Composition Suitable for Treatment of Haemophilia
The present invention relates to pharmaceutical compositions suitable for treatment of haemophilia.
2016/0120953 Factor VIII Conjugates
The present invention relates to FVIII conjugated to heparosan (HEP) polymers, methods for the manufacture thereof and uses of such conjugates. The resultant...
2016/0120952 THERAPEUTIC AGENTS COMPRISING ELASTIN-LIKE PEPTIDES
The present invention provides therapeutic agents and compositions comprising elastin-like peptides (ELPs) and therapeutic proteins. In some embodiments, the...
2016/0120951 ACYLATED GLUCAGON ANALOGUES
The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes and associated metabolic...
2016/0120950 Pharmaceutical Formulations Comprising Incretin Mimetic Peptide and Aprotic Polar Solvent
The present disclosure is directed to stable pharmaceutical formulations and uses thereof.
2016/0120949 USES OF IL-12 IN HEMATOPOIETIC IMMUNOTHERAPY (HIT)
Aspects and embodiments of the instant disclosure provide therapeutic methods and compositions comprising interleukin 12 (IL-12) as a hematopoietic...
2016/0120948 IL-12 COMPOSITIONS AND METHODS OF USE IN HEMATOPOIETIC RECOVERY
Aspects and embodiments of the instant disclosure provide therapeutic methods and compositions comprising interleukin 12 (IL-12) useful for improving...
2016/0120947 METHODS AND COMPOSITIONS FOR MOBILIZING STEM CELLS
The present invention relates to methods and compositions for mobilizing hematopoietic stem cells and/or progenitor cells, and related methods of conditioning...
2016/0120946 COMPOSITIONS COMPRISING GC-MACROPHAGE ACTIVATING FACTOR AND USES THEREOF
A pharmaceutical composition that includes stable Gc macrophage activating factor (GcMAF) or a biologically active variant or fragment thereof and at least one...
2016/0120945 Thymic Regeneration
Methods for regenerating thymic tissues, e.g., for the treatment of subjects who have thymic insufficiency, i.e., whose thymic tissues are absent or atrophied...
2016/0120944 SYSTEMIC AND LOCAL EX VIVO GENE THERAPY OF THE SKELETON
Methods are disclosed herein for increasing bone mass and strength or bone fracture healing in a subject. The methods include administering to the subject a...
2016/0120943 ANGIOGENICALLY EFFECTIVE UNIT DOSE OF FGF AND METHOD OF ADMINISTERING
The present invention provides a unit dose comprising 0.2 .mu.g/kg to 36 .mu.g/kg of a recombinant FGF or an angiogenically active fragment or mutein thereof....
2016/0120942 STABLE NEURAL STEM CELLS COMPRISING AN EXOGENOUS POLYNUCLEOTIDE CODING FOR A GROWTH FACTOR AND METHODS OF USE...
The present disclosure provides a human neural stem cell comprising an exogenous polynucleotide coding for a growth factor such as IGF-1. Also disclosed are...
2016/0120941 METHODS OF USING IL-1 ANTAGONISTS TO TREAT ALZHEIMER'S DISEASE
The invention provides methods of treating, inhibiting, or ameliorating a disease characterized by aberrant deposition of beta amyloid in a subject in need...
2016/0120940 METHODS AND USES OF SLIT FOR TREATING FIBROSIS
The present disclosure provides methods and uses of Slit protein and nucleic acid for inhibiting fibrosis and fibrotic-related disorders, for example, of the...
2016/0120939 METHOD FOR PROMOTING BONE GROWTH USING ACTIVIN-ACTRIIA ANTAGONISTS
In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density.
2016/0120938 P2X7 RECEPTOR AGONIST FOR USE IN PREVENTING OR TREATING KIDNEY INJURY
The present invention relates to the treatment or prevention of kidney injury and in particular acute kidney injury, such as acute kidney injury associated...
2016/0120937 Pharmaceutical compositions comprising 8-substituted dibenzylbutyrolactone lignans
Therapeutic compositions comprising at least one 8-substituted-dibenzylbutyrolactone lignan, preferably a lignan is selected from the group of...
2016/0120936 METHODS OF PREVENTING SURGICAL SITE INFECTIONS
Methods for preventing a tissue infection associated with the site of a tissue disruption, such as a surgical incision. The methods include contacting tissue...
2016/0120935 Sustanined Release Formulation Comprising Octreotide and Two or More Polyactide-co-glycolide Polymers
The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and...
2016/0120934 LUNG INJURY REPAIR COMPOSITIONS AND METHODS
The present invention provides a pharmaceutical composition comprising Protein Kinase C Zeta (PKC-.zeta.) inhibitor and therapeutic methods for preventing or...
2016/0120933 INHIBITORS OF MITOCHONDRIAL FISSION AND METHODS OF USE THEREOF
The present disclosure provides peptides and constructs that inhibit mitochondrial fission, and compositions comprising the peptides or constructs. The present...
2016/0120932 TRANSPLANT SITE-FORMING AGENT, TRANSPLANT SITE-FORMING DEVICE, ANGIOGENIC AGENT AND ANGIOGENIC DEVICE
A method of forming a transplant site, the method comprising a process of contacting SEK-1005 ...
2016/0120931 METHODS AND COMPOSITIONS FOR REGULATING SRCA2A EXPRESSION LEVELS IN MYOCARDIAL INFARCTION
The disclosure provides methods and compositions for increasing SERCA2a expression levels in a mammalian subject in need thereof. The methods comprise...
2016/0120930 COMPOSITION FOR ENHANCING SEMEN QUALITY IN A MALE SUBJECT
The present invention relates to a composition comprising a dry preparation of Alpinia galanga (L.) Willd (Zingiberaceae) or Alpinia conchigera Griff. and a...
2016/0120929 EXTERNAL COMPOSITION FOR SKIN CONTAINING AN ENZYME-TREATED SAPONIN FRACTION DERIVED FROM THE ROOT OF CAMELLIA...
The present invention relates to a composition comprising the saponin fraction derived from the root of camellia sinensis, and more specifically, a composition...
2016/0120928 NASAL SPRAY
The invention relates to novel formulations for treating rhinitis, sinusitis, and allergies with a fast onset of action, long duration (about once or twice...
2016/0120927 PHARMACEUTICAL COMPOSITIONS FOR TREATING THERMAL INJURIES AND WOUNDS COMBINED WITH BONE INJURIES
The present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries. More specifically, the...
2016/0120926 MELALEUCA QUINQUENERVIA EXTRACTS AND USES OF THE SAME
A Melaleuca quinquenervia extract and its uses are provided. The extract is extracted by a first polar solvent, wherein the first polar solvent is a C3-C6...
2016/0120925 DRUG CONTAINING THYME AND PRIMROSE OR THYME AND IVY AS A PDE-4 INHIBITOR
The invention relates to an extract from thyme (Thymus L.) in combination with primrose (Primula veris) or ivy (Hedera helix) for use as PDE-4 inhibitor in the...
2016/0120924 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING SIGNS OR SYMPTOMS OF EYE DISEASE
Compositions and methods for the treatment and prevention of at least one of a sign and a symptom associated with an eye disease are disclosed. Preferred...
2016/0120923 EXTRACT OF CYNARA SSP. AND USES THEREOF
The present invention relates to an extract of Cynara spp. and also to compositions and kits that comprise said extract for the prevention and/or the treatment...
2016/0120922 A Dosing Regime and Formulations for Type B Adenovirus
The present disclosure provides a method of treating a human patient comprising the steps of: systemically administering multiple doses of a parenteral...
2016/0120921 COMPOSITIONS COMPRISING DEHYDRATED MICRO-ORGANISMS, METHOD OF PREPARATION THEREOF, AND USES THEREOF
The invention relates to a composition comprising revivable dehydrated micro-organisms. The invention is characterised in that it further comprises particles...
2016/0120920 COMPOSITIONS AND METHODS COMPRISING BACTERIA FOR IMPROVING BEHAVIOR IN NEURODEVELOPMENTAL DISORDERS
Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in...
2016/0120919 PREVENTIVE OR THERAPEUTIC AGENT FOR RUMINANT ANIMAL MASTITIS
The present invention relates to a substance or method for preventing or treating mastitis in ruminant animals, particularly in dairy cows. Specifically...
2016/0120918 COMPOSITIONS AND METHODS FOR TREATMENT OF MICROBIAL INFECTIONS
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The...
2016/0120917 COMPOSITIONS AND METHODS COMPRISING BACTERIA FOR IMPROVING BEHAVIOR IN NEURODEVELOPMENTAL DISORDERS
Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in...
2016/0120916 COMPOSITIONS AND METHODS COMPRISING BACTERIA FOR IMPROVING BEHAVIOR IN NEURODEVELOPMENTAL DISORDERS
Some embodiments include probiotics for use in treatment of one or more autism spectrum disorder (ASD) or epilepsy in a subject in need thereof. The probiotics...
2016/0120915 METHODS FOR MANIPULATING IMMUNE RESPONSES BY ALTERING MICROBIOTA
The present invention relates to characterizing changes in mammalian microbiota associated with antibiotic treatments and various immunological conditions and...
2016/0120914 TREATING A LYMPHOMA WITH A WHOLE, LEECH SALIVA EXTRACT
Methods are also provided for isolating and using a whole-saliva leech extract in the treatment of a melanoma. The methods can include feeding a ...
2016/0120913 Treating renal cancer with a whole, leech saliva extract
Methods are provided for isolating and using a whole-saliva leech extract. The methods can include feeding a phagostimulatory agent to a leech; inducing a...
2016/0120912 COMPOSITIONS AND METHOD FOR PROMOTING NERVE GROWTH AND REGENERATION
The invention relates generally to the fields of biology and health sciences. More particularly, the invention relates to compositions and methods for...
2016/0120911 TRANSPLANTATION OF CELLS INTO THE NASAL CAVITY AND THE SUBARACHNOID CRANIAL SPACE
A method of transplanting cells into a subject is disclosed. The method comprises transplanting the cells into the paranasal sinus of the subject or the...
2016/0120910 CELL POPULATIONS HAVING IMMUNOREGULATORY ACTIVITY, METHODS FOR THE PREPARATION AND USES THEREOF
The present invention provides a method for treating rheumatoid arthritis comprising the use of mesenchymal stem cells.
2016/0120909 Compositions And Methods For The Treatment Of Tinnitus
In one embodiment, the present invention relates to a method for treating tinnitus in a subject including administering to the subject a composition including...
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