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Patent # Description
2016/0120908 APPLICATION OF MESENCHYMAL STEM CELLS IN PROPHYLAXIS OR TREATMENT OF STRESS RESPONSE-INDUCED WEAKENED IMMUNITY
The present invention discloses the application of mesenchymal stem cells in the prophylaxis or treatment of stress response-induced weakened immunity. More...
2016/0120907 T CELL RECEPTOR-DEFICIENT T CELL COMPOSITIONS
The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to...
2016/0120906 METHODS FOR ENGINEERING HIGHLY ACTIVE T CELL FOR IMMUNOTHERAPHY
The present invention relates to methods for developing engineered T-cells for immunotherapy and more specifically to methods for modifying T-cells by...
2016/0120905 METHODS FOR ENGINEERING ALLOGENEIC AND HIGHLY ACTIVE T CELL FOR IMMUNOTHERAPHY
The present invention relates to methods for developing engineered T-cells for immunotherapy that are non-alloreactive. The present invention relates to...
2016/0120904 Reactive Oxidative Species Generating Materials and Methods of Use
Materials capable of delivering stabilized free radicals to targeted treatment sites. The materials comprise semi-crystalline, hydrolytically degradable...
2016/0120903 Topical Relief Cream Formulation for Allergic Reactions to Poison Ivy, Poison Oak, Poison Sumac, Minor Skin...
A topical relief cream formulation for allergic reactions to poison ivy, poison oak, poison sumac, minor skin irritations and insect bites through chemical...
2016/0120902 MONO (IRON HYDROXYPYRONE) AND COMBINATION (IRON HYDROXYPYRONE AND GI INFLAMMATION INHIBITING AGENTS)...
There is provided a composition or kit of parts comprising: one or more compounds capable of treating and/or preventing an inflammatory disease of the...
2016/0120901 HEMOSTATIC COMPOSITIONS, DEVICES, AND METHODS
Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be...
2016/0120900 COMPOSITION FOR THE ORAL ADMINISTRATION OF MAGNESIUM, IN ASSOCIATION WITH A COMPOSITION FOR TREATING TYPE 2...
The invention relates to a specific composition for oral administration of magnesium, for using in the treatment of type 2 diabetes or the complications...
2016/0120899 Drug Combinations and Uses in Treating a Coughing Condition
The present specification discloses compositions comprising a plurality of therapeutic compound having antitussive activity and methods and uses for treating a...
2016/0120898 METHODS AND COMPOSITIONS FOR THE DISRUPTION OF BIOFILMS AND TREATMENT OF DISORDERS CHARACTERIZED BY THE...
Methods and compositions are provided for the disruption of biofilms and the treatment of disorders characterized by the presence of biofilms and/or abnormally...
2016/0120897 DEXTRAN SULFATE FOR USE IN MOBILIZATION OF CELLS
Dextran sulfate in a range of 3500 and 9500 Da is employed to mobilize cells, such as stem and/or progenitor cells and certain white blood cells, in particular...
2016/0120896 POLYSACCHARIDE COMPOSITIONS AND RELATED METHODS
The disclosure provides LMWH preparations and methods of analyzing LMWH preparations having at least one chain having a glycol split uronic acid residue (UG)...
2016/0120895 MicroRNAs useful for Treating Ovarian Cancer
Described herein are methods for diagnosing ovarian cancer. In particular, certain microRNAs are useful to the response to chemotherapy of ovarian cancer...
2016/0120894 USE OF ADENOSINE ASPARTATE IN THE DIFFERENTIAL ACTIVATION OF MACROPHAGES IN INFLAMMATORY-FIBROGENIC PROCESSES...
The present invention relates to the use of adenosine aspartate for differential activation of macrophages in inflammatory-fibrogenic processes and its reversal.
2016/0120893 METHODS AND COMPOSITIONS RELATING TO MODULATION OF THE PERMEABILITY OF THE BLOOD BRAIN BARRIER
Described herein are methods and compositions relating to modulating the permeability of the blood-brain barrier, e.g. increasing or decreasing the...
2016/0120892 COMBINATION FORMULATION OF TWO ANTIVIRAL COMPOUNDS
Disclosed are pharmaceutical compositions having an effective amount of substantially amorphous ledipasvir and an effective amount of substantially crystalline...
2016/0120891 COMPOSITIONS FOR USE IN CARTILAGE BREAKDOWN
The present invention relates to use of a composition comprising oleuropein and/or hydroxytyrosol for maintenance joint health or prevention or treatment of...
2016/0120890 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS
The invention provides methods, compositions, uses of compositions, assays and kits for modulating brown adipose tissue (BAT) in animals and patients with...
2016/0120889 LIFESPAN EXTENDING AGENT
A lifespan extending agent that is safe for animals, and can easily be ingested in a form that resembles foods. A lifespan extending method is also disclosed....
2016/0120888 ANTICANCER DRUG
An anti-cancer agent and a cancer cell death inducing agent, containing an inositol phospholipid compound, particularly ...
2016/0120887 TUMOR ERADICATION BY INOSITOL-TRIPYROPHOSPHATE
The present invention relates to various salts of inositol tripyrophosphate including the calcium, lithium, beryllium, magnesium, potassium, strontium, barium,...
2016/0120886 PREVENTION, TREATMENT, AND AMELIORATION OF RADIATION INDUCED ENTERITIS
The present invention provides a new method of ameliorating and/or treating enteritis induced by radiation therapy, alone or in combination with other...
2016/0120885 FIXED DOSE COMBINATION FOR PAIN RELIEF WITHOUT EDEMA
Methods for individualized therapy of arthritic pain using a non-steroidal anti-inflammatory drug (COX-2 inhibitor). Said methods comprise basing COX-2...
2016/0120884 PHARMACEUTICAL COMPOSITION FOR TREATING DISEASE ASSOCIATED WITH DEMYELINATION OF NEURONS AND METHOD OF USING...
A method of accelerating remyelination or suppressing demyelination of neurons in a mammal, and a method of treating a disease associated with demyelination of...
2016/0120883 ANTI-INFECTIVE HYDROXY-PHENYL-BENZOATES AND METHODS OF USE
The invention provides a method for preventing or treating a disease caused by an extracellular microorganism, said method comprising systemically...
2016/0120882 COMPOSITION HAVING A BENEFICIAL EFFECT ON THE CARDIOVASCULAR SYSTEM
The present invention is in the field of medical treatment and relates to a formulation for oral administration, such as for instance in the form of tablets or...
2016/0120881 USE OF BUFODIENOLIDES IN DIAGNOSING AND TREATING ESSENTIAL HYPERTENSION
Certain embodiments are directed to methods of identifying patients with essential hypertension by detecting elevated levels of marinobufagenin (MBG) and...
2016/0120880 BILE ACID-BASIC AMINO ACID CONJUGATES AND USES THEREOF
Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a...
2016/0120879 USE OF SUSTAINED RELEASE DEXAMETHASONE IN POST-CATARACT SURGERY INFLAMMATION
The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a...
2016/0120878 DERIVATIVES OF BETULIN
The present invention relates to compounds characterized by having a structure according to the following formula I: ##STR00001## or a pharmaceutically...
2016/0120877 PHARMACEUTICAL COMPOSITIONS FOR SUSTAINED DELIVERY OF BENZODIAZEPINE ANTAGONISTS
The present invention relates to sustained release formulations of benzodiazepine antagonists and their use.
2016/0120876 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER USING PHENOTHIAZINE
The present invention relates to use of antipsychotic phenothiazine derivative for treatment of cancer. The invention also provides a use for manufacture a...
2016/0120875 SUBSTITUTED (E)-N'-(1-PHENYLETHYLIDENE)BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS
Methods of treatment of disorders of uncontrolled cellular proliferation, including cancer, by administering substituted ...
2016/0120874 AGENTS FOR TREATING MULTIPLE MYELOMA
The present invention relates to the use of compounds of a cannabinoid nature for inhibiting viability with increasing doses of myeloma cell lines....
2016/0120873 Method of Inhibition of Respiratory Depression Using Positive Allosteric AMPA Receptor Modulators
The invention is directed to a method for alleviating respiratory depression in a subject as a result of disease of pharmacological agents such as opiates,...
2016/0120872 RAC1 Inhibitors for Inducing Bronchodilation
The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method...
2016/0120871 PHARMACEUTICAL COMBINATIONS OF A PI3K INHIBITOR AND A MICROTUBULE DESTABILIZING AGENT
The present invention relates to a combination comprising (a) a phosphatidylinositol 3-kinase inhibitor selected from ...
2016/0120870 THE PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION COMPRISING RIVAROXABAN
The present invention relates to a process for the preparation of a pharmaceutical composition comprising rivaroxaban, wherein the process comprises a step of...
2016/0120869 SOLID PHARMACEUTICAL DOSAGE FORM
The present invention relates to a solid pharmaceutical dosage from comprising ticagrelor and ASA as pharmaceutically active agents, to a package for storing...
2016/0120868 SUBSTITUTED PYRAZOLOPYRIMIDINES AS KINASES INHIBITORS
The present invention is directed to novel pyrazolopyrimidines, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The...
2016/0120867 STABILIZED PEMETREXED FORMULATION
The present invention relates to a stabilized pemetrexed formulation, and more specifically, to a stabilized pemetrexed formulation comprising acetylcysteine...
2016/0120866 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or...
2016/0120865 TOPICAL TREATMENT OF LOCALIZED SCLERODERMA
Disclosed are compositions and formulations for topical administration that contain a tyrosin kinase inhibitor, such as imatinib or nilotinib. The topical...
2016/0120864 Novel Pyrrole Derivatives
There is provided inter alia novel N-phenyl substituted pyrrole derivatives and their use in therapy, especially in the treatment of bacterial (e.g....
2016/0120863 SLC2A TRANSPORTER INHIBITORS
Provided is a SLC2A class I transporter inhibitor compound for use in medicine, which compound comprises the following formula: ##STR00001## wherein A and Z may...
2016/0120862 Novel Suicidal LSD1 Inhibitors Targeting SOX2-Expressing Cancer Cells
Disclosed are inhibitors of lysine-specific demethylase I (LSD1); synthetic methods for making the compounds; pharmaceutical compositions comprising the...
2016/0120861 Compositions and Methods for Treating an Arrhythmia with an Opioid Antagonist
Disclosed in certain embodiments is a method of treating an arrhythmia comprising administering to a patient in need thereof an effective amount of an opioid...
2016/0120860 METHODS AND AGENTS FOR TREATING TYROSINASE-POSITIVE ALBINISM
Methods for treating a subject with tyrosinase-positive albinism; agents and compositions thereof for use in treating tyrosinase-positive albinism; and...
2016/0120859 PHARMACEUTICAL FORMULATIONS OF A HIF HYDROXYLASE INHIBITOR
The present disclosure relates to pharmaceutical formulations of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid and methods of use...
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