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Patent # Description
2016/0136153 DIVERSION-RESISTANT OPIOID FORMULATIONS
The present invention provides a composition comprising an opioid agonist, and a polymer-antagonist conjugate. The polymer-antagonist conjugate preferably does...
2016/0136152 OXYMORPHONE CONTROLLED RELEASE COMPOSITIONS
The invention pertains to a method of relieving pain by administering a controlled release pharmaceutical tablet containing oxymorphone which produces a mean...
2016/0136151 Orvinol and Thevinol Derivatives Useful in the Treatment of Anxiety or a Compulsive Disorder
The invention provides a method of treating anxiety or a compulsive disorder in a subject comprising administering to the subject a compound having formula 2: ...
2016/0136150 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK
The present invention relates to compounds of formula I: ##STR00001## in which n, R.sub.1, R.sub.2, R.sub.3a, R.sub.4 and R.sub.5 are defined in the Summary of...
2016/0136149 HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
The present invention comprises compounds of Formula I. ##STR00001## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 R.sup.8, and R.sup.9...
2016/0136148 SOLID DISPERSIONS OF AMORPHOUS PAROXETINE MESYLATE
The invention relates to solid dispersions containing paroxetine mesylate. One solid dispersion contains amorphous paroxetine mesylate and a methacrylic...
2016/0136147 EXTENDED RELEASE NICOTINAMIDE FORMULATION
The invention provides various extended release granules of nicotinamide. Granule properties can be enhanced by the inclusion of a conductive filler.
2016/0136146 COMPOSITIONS AND METHODS FOR TREATING PRIMARY EFFUSION LYMPHOMA
Methods for treating primary effusion lymphoma (PEL) are provided. The methods include administering to a patient in need thereof an effective amount of an...
2016/0136145 BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF
Compositions for treating a condition associated with activity of a muscarinic receptor (e.g., one or more of M.sub.1, M.sub.2, M.sub.3, M.sub.4, M.sub.5) and...
2016/0136144 COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS
The invention relates to a novel drug combination therapy useful in the treatment of dementia comprising administering a 1-aminocyclohexane derivative such as...
2016/0136143 COMPOSITIONS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS
The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates...
2016/0136142 TREATMENT OF PANCREATIC AND RELATED CANCERS WITH 5-ACYL-6,7-DIHYDROTHIENO[3,2-C]PYRIDINES
Methods for inhibiting the growth of pancreatic cancer cells or other cancer cells driven by Sonic hedgehog are disclosed. The method involves exposing the...
2016/0136141 RIFAXIMIN READY-TO-USE SUSPENSION
A stable, taste-masked, ready-to-use suspension comprising rifaximin dispersed in a suspension base and one or more pharmaceutically acceptable additive(s)....
2016/0136140 Chemical Compounds
The invention concerns compounds of Formula (I) ##STR00001## or pharmaceutically-acceptable salts thereof, wherein R.sup.1 to R.sup.5 have any of the meanings...
2016/0136139 ITE FOR CANCER INTERVENTION AND ERADICATION
A method of cancer intervention or eradication by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named...
2016/0136138 DRUG FOR TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE
The present invention provides a compound useful in the prevention and treatment of nonalcoholic fatty liver disease. The invention relates to a drug for the...
2016/0136137 METHOD FOR TREATING, PREVENTING, OR REDUCING THE RISK OF SKIN INFECTION
The present invention relates to methods for treating acne and other skin infections caused or mediated by Propionibacterium acnes, Gardnerella vaginalis, or...
2016/0136136 THERAPEUTIC APPROACHES FOR TREATING ALZHEIMER DISEASE AND RELATED DISORDERS THROUGH A MODULATION OF SYNAPSE...
Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate...
2016/0136135 METHOD OF TREATMENT OF CNS DISORDERS
The invention comprises a method of treatment of CNS disorders by a pharmaceutical agent exhibiting combined noradrenergic, serotonergic or dopaminergic...
2016/0136134 ANTIVIRAL COMPOUNDS HIGHLY EFFECTIVE AS HCV-NS5A INHIBITOR
Provided are compounds antiviral compounds represented by formula Ia and Ib: ##STR00001## that are highly potent as HCV NS5A inhibitors, where the structural ...
2016/0136133 MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES
The present invention relates to the use of indolinones of general formula ##STR00001## substituted in the 6 position, wherein R.sub.1 to R.sub.5 and X are...
2016/0136132 A PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF MELANOMA
The present invention relates to a pharmaceutical combination comprising a cyclin dependent kinase (CDK) inhibitor represented by a compound of formula I (as...
2016/0136131 FORMULA COMPRISING A HYPOLIPIDEMIC AGENT
The present invention relates to the stable pharmaceutical composition of a suitable hypolipidemic agent. Preferably, the present invention discloses novel...
2016/0136130 Oral Ultraviolet Resistance Enhancer
To provide an ultraviolet resistance enhancer capable of enhancing resistance of the skin to ultraviolet rays by oral ingestion, thereby reducing or...
2016/0136129 CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY
Novel chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents...
2016/0136128 THE USE OF PHYTOCANNABINOIDS IN THE TREATMENT OF OVARIAN CARCINOMA
The present invention relates to the use of phytocannabinoids in the treatment of ovarian cancer. Preferably the phytocannabinoid is selected from the group...
2016/0136127 USE OF TETRAHYDROCANNABINOL AND/OR CANNABIDIOL FOR INCREASING RADIOSENSITVITY IN THE TREATMENT OF A BRAIN TUMOUR
The present invention relates to the use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer. Preferably the phytocannabinoids used...
2016/0136126 Pharmaceutical compositions of Anisomelic acid and the use thereof
A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The...
2016/0136125 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONSCOMPRISING A FUMARIC ACID ESTER
The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are...
2016/0136124 ADMINISTRATION OF A FOOD COMPOSITION PRODUCT
Method for orally administrating a subject a food composition product, referred to as "Preload Meal," before administering a main meal to the subject. The food...
2016/0136123 TREATMENT OF AUTOPHAGY-RELATED DISORDERS
The present invention relates to the use of neutral lipids, including triglycerides, diglycerides and monoglycerides which may be used to increase neutral...
2016/0136122 METHODS FOR TREATING PSORIATIC ARTHRITIS
Methods, agents and compositions thereof for treating psoriatic arthritis (PsA) are encompassed herein.
2016/0136121 USE OF CILASTATIN TO REDUCE THE NEPHROTOXICITY OF DIFFERENT COMPOUNDS
Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the...
2016/0136120 TRANSDERMAL DELIVERY KITS
Provided are kits containing a base composition and an active pharmaceutical ingredient for transdermal delivery of active pharmaceutical ingredients. Examples...
2016/0136119 DP2 ANTAGONIST AND USES THEREOF
Described herein is the DP.sub.2 antagonist [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluoromethyl-biphenyl- -3-yl]-acetic acid, or a pharmaceutically...
2016/0136118 COMPOSITIONS AND METHODS FOR THE TREATMENT OF A COMMON COLD AND SYMPTOMS THEREOF
Embodiments of the invention relate to methods and compositions for treating symptoms related to inflammatory conditions and to methods and compositions for...
2016/0136117 BOLUS DOSE OF HYDROXYCITRIC ACID WITH GLYCEROL
A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of...
2016/0136116 Carmustine Pharmaceutical Composition
The present invention provides pharmaceutical formulations of lyophilized carmustine suitable for pharmaceutical use. The present invention further provides...
2016/0136115 T TYPE CALCIUM CHANNEL INHIBITORS
The present invention provides novel T type calcium channel inhibitors of formula (I), the use thereof in the treatment of a disease or condition in a mammal...
2016/0136114 METHOD FOR THE TREATMENT OF DRAVET SYNDROME
A method of treating and/or preventing Dravet Syndrome in a patient such as a patient previously diagnosed with Dravet Syndrome, by administering an effective...
2016/0136113 TOPICAL VASOCONSTRICTOR PREPARATIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY
Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy...
2016/0136112 COMPOSITION COMPRISING TAPENTADOL IN A DISSOLVED FORM
The present invention relates to a composition comprising tapentadol in a dissolved form and oral dosage forms comprising said composition. The invention...
2016/0136111 TREATMENT OF CNS DISORDERS WITH trans 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE
Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine; and (1S,4R)-trans...
2016/0136110 Method for Treating a Neurodegenerative Event
A method of neuroprotection or treating or healing a wound, orifice, surgical site or a neurodegenerative event in an individual or animal via modulation of at...
2016/0136109 COMPOSITIONS FOR TISSUE STABILIZATION
Collagen crosslinking/stabilization composition optionally in combination with elastin crosslinking composition as treatment of vascular aneurysms, methods of...
2016/0136108 HYDROXYTYROSOL COMPOSITIONS FOR TREATMENT OF CARTILAGE INJURIES IN JOINTS
The invention relates to the use of hydroxytyrosol for inducing or enhancing cartilage repair or cartilage regeneration. Furthermore, the invention relates to...
2016/0136107 STORAGE STABLE TRANSDERMAL PATCH OF ROTIGOTINE
Disclosed is a transdermal delivery device comprising a backing layer, a release liner, and an adhesive layer between the backing layer and the release liner,...
2016/0136106 Nanoparticles Leverage Biological Membranes to Target Pathogens for Disease Treatment and Diagnosis
Provided are methods, combinations and pharmaceutical compositions for treating or preventing an infection in a subject using a nanoparticle comprising a) an...
2016/0136105 Compositions and Methods for the Delivery of Therapeutics
The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.
2016/0136104 WIRELESS COMMUNICATIONS SYSTEM INTEGRATING ELECTRONICS INTO ORALLY INGESTIBLE PRODUCTS FOR CONTROLLED RELEASE...
Various embodiments of the present disclosure include a consumable capsule containing an active ingredient in at least one compartment movably sealed by a...
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