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Patent # Description
2016/0151505 BIO-ORTHOGONAL DRUG ACTIVATION
The invention relates to a Prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal...
2016/0151504 PEPTIDES USEFUL AS CELL-PENETRATING PEPTIDES
A method of penetrating a cell where the cell is contacted with a complex that includes (A) a peptide comprising at least 8 consecutive amino acids of the...
2016/0151503 COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY-WATER SOLUBLE DRUGS
The disclosure relates generally to ionic salts, particularly low-melting ionic salts such as ionic liquids, of poorly-water soluble drugs. The disclosure...
2016/0151502 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
2016/0151501 POWDER MIXTURES FOR ANTIBIOTIC DRY SYRUP FORMULATIONS
The present invention provides a pharmaceutical formulation prepared as dry syrups representing mere powder mixtures of beta-lactam antibiotics as active...
2016/0151500 METHOD FOR THE TREATMENT OF NANOHYDROGELS
A method for treating nanohydrogels comprising--a dispersion step, in which a nanohydrogel obtained from a polysaccharide functionalized with hydrophobic...
2016/0151499 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
2016/0151498 Nanoparticle Compositions
The present invention relates to compositions and methods of formulating nanoparticle drugs for cancer treatment in particular for intravenous administration...
2016/0151497 pH SENSITIVE CARRIER AND PREPARATION METHOD THEREOF, AND pH SENSITIVE DRUG AND pH SENSITIVE DRUG COMPOSITION...
A pH sensitive carrier which includes at least one pH sensitive compound selected from the group consisting of deoxycholic acid, cholic acid, ursodeoxycholic...
2016/0151496 SUSTAINED RELEASE EYE DROP FORMULATIONS
This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular,...
2016/0151495 IMMUNOGLOBULIN PREPARATION
The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
2016/0151494 TARGETING THYMIDINE KINASE PHOTOSENSITIZER AND PHARMACEUTICAL COMPOSITION AND USE FOR CANCER TREATMENT THEREOF
A targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof is provided, which improves the selectivity of...
2016/0151493 Heating Elements Having Plasmonic Nanoparticles for Localized Heating
In one embodiment, a heating element includes a central particle and a plurality of plasmonic nanoparticles attached to the central particle, wherein the...
2016/0151492 Monoclonal Antibodies for Ebola and Marburg Viruses
Described herein are a number of Ebola monoclonal antibodies.
2016/0151491 CELLS PREPARED BY TRANSIENT TRANSFECTION AND METHODS OF USE THEREOF
Compositions and methods of making cells using RNA, and cells made using the disclosed compositions and methods are also provided. In exemplary embodiments,...
2016/0151490 METHODS AND COMPOSITIONS FOR TREATING CANCER
Described are compositions and methods relating to immune cells which express both a chimeric antigen receptor which binds to the IL13 receptor .alpha.-2...
2016/0151489 COMBINATION OF A LIGAND OF HVEM AND AN IMMUNOTOXIN FOR USE IN THERAPY
The invention relates to i) a ligand of HVEM, and ii) an immunotoxin, as a combined preparation for simultaneous, separate or sequential use in the treatment...
2016/0151488 Methods for Treating Juvenile Idiopathic Arthritis
The invention provides methods and compositions for the treatment of juvenile idiopathic arthritis (JIA) where a TNF.alpha. inhibitor, such as a human...
2016/0151487 FCRN-BINDING ABOLISHED ANTI-IGF-1R ANTIBODIES AND THEIR USE IN THE TREATMENT OF VASCULAR EYE DISEASES
The invention provides anti-IGF-1R antibodies with abolished FcRn-binding and methods of using the same for the treatment of vascular eye diseases.
2016/0151486 CD40 Signalling Inhibitor and a Further Compound, Wherein the Further Compound is a Bile Acid, a Bile Acid...
The invention provides a CD40 signalling inhibitor and a further compound for use in the treatment of chronic inflammatory disease in an individual in need...
2016/0151485 POLYSACCHARIDE SUITABLE TO MODULATE IMMUNE RESPONSE
Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or...
2016/0151484 METHODS AND FORMULATIONS WHICH ALLOW THE MODULATION OF IMMUNE RESPONSES RELATED TO THE ADMINISTRATION OF A...
The present invention is related to methods of preparing a pharmaceutical formulation comprising a biopharmaceutical drug, which methods allows the modulation...
2016/0151483 BETA-GLYCOLIPIDS FOR USE AS ADJUVANTS
The present invention relates to beta-glycolipid derivatives, their preparation and use as adjuvants in vaccines, as being suitable for being co-administered...
2016/0151482 MESOPOROUS ALUM NANOPARTICLES AS A UNIVERSAL PLATFORM FOR ANTIGEN ADSORPTION, PRESENTATION, AND DELIVERY
The present invention relates to mesoporous alum nanoparticles which can be used as a universal platform for antigen adsorption, presentation and delivery to...
2016/0151481 PHARMACEUTICAL PRODUCT COMPRISING MITE ALLERGEN EXTRACT(S) AND A METHOD FOR THE MANUFACTURE THEREOF
The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and...
2016/0151480 Universal Influenza Vaccine
The present invention includes an isolated antigen against influenza A and a method of making the same that includes an ectodomain of influenza A Matrix...
2016/0151479 METHOD FOR PREPARING VIROSOMES
Described are methods for preparing virosomes comprising the steps of: (a) providing an enveloped virus, and optionally inactivating the virus; (b)...
2016/0151478 Novel Flavivirus Antigens
The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to...
2016/0151477 DENGUE VIRUS VACCINE COMPOSITIONS AND METHODS OF USE THEREOF
The present invention relates to dengue virus vaccine compositions comprising a first and a second dengue vaccine, wherein the first dengue vaccine is a live,...
2016/0151476 COMBINATION NEISSERIAL COMPOSITIONS
Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term...
2016/0151475 Bacterial Ribonucleic Acid Cell Wall Compositions and Methods of Making and Using Them
The present invention relates to novel bacterial and mycobacterial compositions containing RNA and cell walls, and methods for making and using these...
2016/0151474 VACCINATION IN ELDERLY PATIENTS
The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in an elderly...
2016/0151473 Vaccines Using High-Dose Cytokines
The present invention relates to the field of cancer immunotherapy. In particular, vaccines are administered in conjunction with high doses of cytokines to...
2016/0151472 METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER OR INDUCING A HUMORAL IMMUNE RESPONSE AGAINST PROSTATE CANCER
The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an...
2016/0151471 INDUCIBLE REGULATORY T-CELL GENERATION FOR HEMATOPOIETIC TRANSPLANTS
The present invention provides methods and compositions for converting non-Tregs into Tregs. The converted Tregs are referred to as inducible Tregs (iTregs)....
2016/0151470 T-CELL IMMUNOGENS DERIVED FROM ANTI-VIRAL PROTEINS AND METHODS OF USING SAME
Isolated polypeptides related to endogenous anti-viral polypeptides; and compositions, including immunogenic compositions, comprising a subject isolated...
2016/0151469 IMMUNE MODULATION BY TLR ACTIVATION FOR TREATMENT OF FILOVIRUS INFECTIONS INCLUDING EBOLA
Means and compositions of matter are disclosed for stimulation of innate immunity in controlling, substantially reducing, and/or clearing filoviral infections...
2016/0151468 Suture Line Administration Technique Using Botulinum Toxins
The present invention utilizes patient-specific landmarks in order to treat headache pain. In one aspect, the present invention relates to the administration...
2016/0151467 COMPOSITION COMPRISING FILLER AND BOTULINUM TOXIN FOR ALLEVIATING SKIN WRINKLES OR AGING OR TREATING...
The present invention discloses a composition comprising a filler and a botulinum toxin for improving skin wrinkles, preventing skin aging, or treating...
2016/0151466 BOTULINUM NEUROTOXINS WITH MODIFIED LIGHT CHAIN SPECIFITY AND METHODS FOR PRODUCING SAME
A protease directed to a non-neuronal SNARE protein is described. The protease is produced by selective mutation of a botulinum neurotoxin light chain, and is...
2016/0151465 METHODS FOR INDUCING PARTIAL APOPTOSIS USING CASPASE POLYPEPTIDES
The technology relates in part to methods for inducing partial apoptosis of cells that express an inducible caspase polypeptide. The technology further relates...
2016/0151464 LOW VISCOSITY COMPOSITIONS COMPRISING A PEGYLATED GLA-DOMAIN CONTAINING PROTEIN
The present invention relates to a method for lowering the viscosity of compositions comprising Vitamin K-dependent proteins.
2016/0151463 COMBINATION TREATMENT FOR ATOPIC DERMATITIS
The invention relates to the field of medicine, specifically to the field of treatment of dermatitis or eczema, even more specifically to the field of...
2016/0151462 SOLID COMPOSITIONS COMPRISING A GLP-1 AGONIST AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID
The present invention relates to solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and their use in medicine.
2016/0151461 Cardio-Metabolic and Vascular Effects of GLP-1 Metabolites
The present invention relates to compositions and methods for treatment and/or prevention of a cardiovascular disease. In one embodiment, the compositions and...
2016/0151460 Method of treating skeletal dysplasias using vessel dilator
C-natriuretic peptide (CNP) has been shown to regulate proliferation of mouse and rat osteoblasts. Genetic deletion of CNP results in dwarfism. CNP effects on...
2016/0151459 THERAPEUTIC METHOD OF TREATING METABOLIC DISORDERS
A method of treating metabolic disorders in a mammal is provided. The method comprises the step of administering to the mammal a meteorin-like protein or...
2016/0151458 Use Of Unacylated Ghrelin, Fragments And Analogs Thereof As Antioxidant
The present invention relates to methods for protecting a subject, tissues and/or organs from a subject against oxidative stress-induced damage, such as but...
2016/0151457 OPHTHALMIC USES OF TOXIN-BASED THERAPEUTIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF
Disclosed herein are methods of treating ophthalmic conditions such as dry eye and uveitis by administering a pharmaceutical composition including a...
2016/0151456 LIPOPEPTIDE INHIBITORS OF RAS ONCOPROTEINS
A method of inhibiting Ras activity in a cell comprising introducing a peptide or peptidomimetic into the cell, wherein the peptide or peptidomimetic is...
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