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Patent # Description
2016/0151405 Pappalysin Regulator
A method is provided of decreasing or increasing the activity of a Pappalysin polypeptide by decreasing or increasing the level of interacting Pappalysin and...
2016/0151404 Nucleic Acid Particles, Methods and Use Thereof
The present invention provides, among other things, a particle which includes a core comprised of self-assembled one or more nucleic acid molecules, the core...
2016/0151403 SMALL MOLECULE MODULATORS OF P53 FAMILY SIGNALING
This invention relates to methods for identifying compound capable of activating p53-responsive transcriptional activity in a p53-deficient tumor cell and the...
2016/0151402 METHOD OF TREATING PULMONARY DISORDERS WITH LIPOSOMAL AMIKACIN FORMULATIONS
Disclosed herein are methods of treating pulmonary disorders comprising administering to the patient an effective dose of a nebulized liposomal amikacin...
2016/0151401 GLYCOLIPIDS AS TREATMENT FOR DISEASE
This invention provides compounds, compositions, and methods for treating a disorder selected from cancer, hyperinsulinemia, hypoglycemia, hyperinsulinemia...
2016/0151400 HYBRID SCFA-HYDROXYL-DERIVATIZED MONOSACCHARIDES, METHODS OF SYNTHESIS, AND METHODS OF TREATING DISORDERS
Described herein are fatty acid carbohydrate-hydroxyl-hybrid compounds and derivatives thereof, and methods of treating or preventing disease and disease...
2016/0151399 BORON-CONTAINING SMALL MOLECULES
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal...
2016/0151398 Compositions Comprising Zoledronic Acid or Related Compounds for Treatment of Complex Regional Pain Syndrome
Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. Although an oral dosage...
2016/0151397 DOXYCYCLINE COMPOSITION
The present invention relates to a once daily pharmaceutical composition comprising doxycycline, a controlled-release polymer, and one or more pharmaceutically...
2016/0151396 PHARMACEUTICAL COMPOSITION OF DOXYCYCLINE WITH REDUCED FOOD EFFECT
The present invention relates to a once daily pharmaceutical composition comprising doxycycline and one or more pharmaceutically acceptable excipients, wherein...
2016/0151395 Tabletting Process
A process for producing a compressed solid dosage form containing an active ingredient. The process includes a step of preparing core elements containing the...
2016/0151394 Methods and Compositions for Treating Cancer
Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a ...
2016/0151393 PULMONARY PHARMACEUTICAL FORMULATIONS
The present invention provides improved pharmaceutical formulations for pulmonary delivery having improved chemical and physical stability of the therapeutic,...
2016/0151392 SELF-NANOEMULSION OF POORLY SOLUBLE DRUGS
The present disclosure pertains to pharmaceutical formulation comprising low aqueous solubility drug, a solubilizer, and optionally at least one ...
2016/0151391 NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF
Described herein are nitrated lipids and methods of making and using the nitrated lipids.
2016/0151390 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML)
The invention relates to compositions, methods, and kits for treating subjects infected by or at risk of infection with a DNA virus (e.g., a JC Virus or a BK...
2016/0151389 USE OF ERGOSTATRIEN-3 -OL
A method for inhibiting the activation of mitogen-activated protein kinase (MAPK) signaling pathway in a neuroglial cell of a subject in need, comprising...
2016/0151388 Methods and Compositions Related to Glucocorticoid Receptor Antagonism and Prostate Cancer
Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid...
2016/0151387 COMPOSITIONS HAVING C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified...
2016/0151386 SUSTAINED RELEASE FORMULATIONS FOR THE TREATMENT OF INTRAOCULAR PRESSURE OR GLAUCOMA
The present embodiments provide for methods of treating elevated intraocular pressure or glaucoma using a sustained release medicament consisting of...
2016/0151385 STABLE FORMULATIONS FOR PARENTERAL INJECTION OF SMALL MOLECULE DRUGS
Disclosed is a stable liquid formulation for parenteral injection comprising a biocompatible non-aqueous solvent and a small molecule drug, or a salt thereof,...
2016/0151384 NEW MODUS OF ADMINISTRATION OF IRON, AND NEW FORMULATIONS ADAPATED FOR THE SAID GOAL
A new modus and a new regimen of administration of divalent iron relates to therapy of hyposideremia, at the same time reducing toxic side effects. New...
2016/0151383 METHODS FOR TREATMENT OF DISEASES
The present disclosure relates to methods of treating a range of diseases or conditions. The methods involve administration of a superoxide dismutase mimetic.
2016/0151382 Cooperative Medication Combination Systems
This invention aims to capture and teach the high-level concept of combining doses of medications in unconventionally substandard amounts, for the treatment of...
2016/0151381 SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS
Salts of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with optically active acids, and pharmaceutical compositions comprising them that are useful...
2016/0151380 THERAPIES FOR DISEASES CAUSED BY ARTHROPOD-BORNE PARASITES
The present disclosure provides methods for treating or preventing diseases caused by arthropod-borne parasites by administration of a protein kinase inhibitor...
2016/0151379 COMBINATION THERAPIES FOR MALARIA
The present disclosure provides methods for treating or preventing malaria by administration of a protein kinase inhibitor and optionally one or both of a...
2016/0151378 SALT OF 3-[(3--2-OXO-2,3-DIHYDRO-1H-INDOL-5-YL)METHYL]-1,3-THIAZOLIDINE-2,- 4-DIONE, ITS PREPARATION, AND...
3-[3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydr- o-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione methanesulphonate of formula...
2016/0151377 USE OF SIGMA RECEPTOR LIGANDS FOR THE PREVENTION AND TREATMENT OF PAIN ASSOCIATED TO INTERSTITIAL...
The invention refers to the use of a sigma ligand, particularly a sigma ligand of formula (I) to prevent and/or treat pain associated to interstitial...
2016/0151376 BISARYL (THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS
Described are compounds that are modulators of the S1P receptors, and pharmaceutical compositions comprising the compounds. Also described are methods of using...
2016/0151375 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT
The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to...
2016/0151374 METHOD OF USING VASOCONSTRICTIVE AGENTS DURING ENERGY-BASED TISSUE THERAPY
A mammal undergoing an energy-based therapy is treated by administering at least one vasoconstrictive agent to the mammal prior to or during the procedure. The...
2016/0151373 COMBINATION TREATMENT OF CANCER
The present invention relates to a combination comprising AZD5363, or a pharmaceutically acceptable salt thereof, and at least one androgen receptor signalling...
2016/0151372 PYRROLOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER
Compounds of Formula I: ##STR00001## wherein: one of X and X' is N and the other of X and X' is C, are described, along with compositions containing the same and...
2016/0151371 COMPOSITION FOR REGULATING IMMUNOLOGICAL ACTIVITY IN INTESTINE AND USE THEREOF
The present invention relates to an antimicrobial composition for uracil non-secretory (URA-) bacteria, comprising uracil, uracil precursors, uracil analogs,...
2016/0151370 Substituted Benzylpyrazoles
Compounds of formula (I) and their use as pharmaceutical. ##STR00001##
2016/0151369 SUBSTITUTED 3-PHENYLPROPYLAMINE DERIVATIVES FOR THE TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and...
2016/0151368 THERAPEUTIC FORMULATION AND METHODS OF TREATMENT
The present disclosure relates pharmaceutical formulations comprising hydralazine in the treatment of eye diseases and conditions with the formulations. The...
2016/0151367 METHODS OF USING PHTHALAZINONE KETONE DERIVATIVES
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use...
2016/0151366 Compositions and Methods for Treating Autism Spectrum Disorders
Methods and compositions for use in treating autism spectrum disorder (ASD) include use of specific CNS penetrant p38.alpha. MAPK inhibitors having the...
2016/0151365 TRIZOL-1-OL ANALOGS ANTI-RETROVIRAL LATENCY DRUGS
In one aspect, the invention relates to triazol-1-ol compounds, analogs thereof, compositions comprising same, and methods of using same, alone or in...
2016/0151364 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AND 4-IMIDAZOTRIAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS
The present invention relates to 6-5 membered fused pyridine ring compounds according to Formula (I) ##STR00001## or a pharmaceutically acceptable salt thereof...
2016/0151363 Cadherin-11 Inhibitors and Methods of Use Thereof
Cadherin-11 inhibitors and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include...
2016/0151362 TARGETING HUMAN THYMIDYLATE KINASE INDUCES DNA REPAIR TOXICITY IN MALIGNANT TUMOR CELLS
The present invention relates to novel TMPK inhibitor and their methods of use. In particular, it relates to novel TMPK inhibitor of Formula (I) and...
2016/0151361 CONTROLLED RELEASE HYDROCODONE FORMULATIONS
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a...
2016/0151360 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
2016/0151359 Method of Treating Dyskinesia
Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action .mu.-opioid receptor ...
2016/0151358 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
2016/0151357 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
2016/0151356 Pharmaceutical Formulation Containing Gelling Agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
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