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Patent # Description
2016/0160232 ALS INHIBITOR HERBICIDE TOLERANT MUTANT PLANTS
The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as B. napus or B. juncea plants, progeny and parts thereof...
2016/0160231 USE OF POLYPEPTIDES AND NUCLEIC ACIDS FOR IMPROVING PLANT GROWTH, STRESS TOLERANCE AND PRODUCTIVITY
Transgenic plants that over-express a Big Grain 2 (BG2) gene and methods of using such for improving the growth, productivity, or stress tolerance of a plant.
2016/0160230 TRANSGENIC MAIZE
The present invention provides a method of producing transgenic plants which are drought resistant, plants obtainable by the method and uses thereof.
2016/0160229 METHODS OF PRODUCING ANTIBODY-RICH CANNABIS AND HONEYSUCKLE PLANTS
A method of producing antibody-rich cannabis and honeysuckle plants, and receiving the antibodies therefrom within a human body, is described. Antibody...
2016/0160228 TRANSGENIC ALOE PLANTS FOR PRODUCTION OF PROTEINS AND RELATED METHODS
The present inventions provide transgenic aloe plants and recombinant constructs for transforming aloe plants, aspects of which, may be applied to other...
2016/0160227 GENE FOR INCREASING PLANT WEIGHT AND METHOD FOR USING THE SAME
A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be...
2016/0160226 GENE FOR INCREASING PLANT WEIGHT AND METHOD FOR USING THE SAME
A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be...
2016/0160225 PEPPER WITH NOVEL FLAVOR
The present invention relates to a pepper plant (Capsicum annuum L.) which may comprise a QTL that leads to the plant producing fruits that have a novel...
2016/0160224 CRYPTOSPORIDIUM TRANSFECTION METHODS AND TRANSFECTED CRYPTOSPORIDIUM CELLS
This disclosure describes, in one aspect, a method of transfecting a Cryptosporidium organism. Generally, the method includes introducing into a...
2016/0160223 RECOMBINANT MICROORGANISMS EXHIBITING INCREASED FLUX THROUGH A FERMENTATION PATHWAY
The invention provides a recombinant, carboxydotrophic Clostridium bacterium that expresses one or more of pyruvate:ferredoxin oxidoreductase (EC 1.2.7.1),...
2016/0160222 DNA MOLECULES AND METHODS
The present application discloses a DNA molecule comprising a modified Group II intron which does not express the intron-encoded reverse transcriptase but...
2016/0160221 NOVEL STRINGENT SELECTABLE MARKERS
The present invention relates to nucleic acid constructs comprising selectable marker genes in a multicistronic transcription unit for use in the generation...
2016/0160220 Methods and Compositions for Treating Autoimmune Disorders by Targeting Kv1.3 Ion Channels with Functionalized...
Synthesis and pharmaceutical compositions of antibody-functionalized nanovesicles encapsulating ion channel knockout siRNA, and methods of treating autoimmune...
2016/0160219 COMPOSITION CONTAINING PPAR-gamma NEDDYLATION INHIBITOR FOR INHIBITING ADIPOCYTE DIFFERENTIATION AND USE THEREOF
Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for...
2016/0160218 USE OF APTAMERS IN THERAPY AND/OR DIAGNOSIS OF AUTOIMMUNE DISEASES
The present invention is directed to an aptamer comprising or consisting of the nucleic acid sequence of SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and/or a...
2016/0160217 COMPOSITIONS AND METHODS FOR CHARACTERIZING AND TREATING MUSCULAR DYSTROPHY
Compositions and methods for identifying new treatments for Facioscapulohumeral muscular dystrophy (FSHD), and uses thereof.
2016/0160216 TTV MIRNA SEQUENCES AS AN EARLY MARKER FOR THE FUTURE DEVELOPMENT OF CANCER AND AS A TARGET FOR CANCER...
Described are TTV miRNAs and probes and primers comprising part of said TTV miRNA polynucleic acid. The use of said compounds for diagnosis of cancer or...
2016/0160215 POLYNUCLEOTIDES FOR MULTIVALENT RNA INTERFERENCE, COMPOSITIONS AND METHODS OF USE THEREOF
The present invention includes bivalent or multivalent nucleic acid molecules or complexes of nucleic acid molecules having two or more target-specific...
2016/0160214 FORMULATIONS COMPRISING ANTISENSE NUCLEOTIDES TO CONNEXINS
A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable...
2016/0160213 METHODS OF TREATING CANCER AND PREVENTING CANCER DRUG RESISTANCE
Provided herein are methods of treating and/or preventing cancer drug resistance using modulators of chromatin modifiers (e.g., antagonists of chromatin...
2016/0160212 Compositions and Methods for Regulating Gene Expression via RNA Interference
The present disclosure provides compositions and methods for regulating gene expression via RNA-mediated silencing. The present disclosure also provides...
2016/0160211 TWO DIMENSIONAL CAPILLARY ELECTROPHORESIS APPARATUS
The present disclosure describes an apparatus for identifying a polynucleotide capable of binding a target. The apparatus comprises a first, second, and third...
2016/0160210 RNA-Guided Human Genome Engineering
A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of...
2016/0160209 SEQUENTIAL DELIVERY DEVICE AND METHOD
A reagent delivery method includes placing a reagent delivery column including a plurality of reagent storage elements therein in a centrifugal device,...
2016/0160208 CAPILLARY BARRIERS FOR STAGED LOADING OF MICROFLUIDIC DEVICES
Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic...
2016/0160207 PROBIOTIC BACTERIA COMPRISING METALS, METAL NANOPARTICLES AND USES THEREOF
The invention relates to probiotic bacteria selected from lactic acid bacteria, such as Lactobacillus and Bifidobacteria, having metals and/or metal...
2016/0160206 Aldehyde-Tagged Protein-Based Drug Carriers and Methods of Use
The disclosure provides aldehyde-tagged protein carriers that can be covalently and site-specifically bound to drug to provide a drug-containing scaffold. The...
2016/0160205 PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS
The present invention is directed to methods and compositions for activating a Parkin ligase by administering to a subject in need thereof a therapeutically...
2016/0160204 MEVALONATE DIPHOSPHATE DECARBOXYLASE VARIANTS
Described are mevalonate diphosphate decarboxylase variants having improved activity in converting 3-phosphonoxyisovalerate into isobutene. Such variants can...
2016/0160203 COORDINATED COEXPRESSION OF THROMBIN
The present invention provides methods of producing thrombin using coordinated coexpression systems, and particularly inducible coexpression systems, capable...
2016/0160202 NOVEL METALLOPROTEASES
Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods...
2016/0160201 Polypeptides having Cellobiohydrolase Activity and Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention...
2016/0160200 METHOD FOR PRODUCING HIGHLY ACTIVE CELLOBIOHYDROLASE AND HIGHLY ACTIVE CELLOBIOHYDROLASE
An object of the invention is to provide cellobiohydrolase with high activity. The activity of cellobiohydrolase can be improved by substituting, with alanine,...
2016/0160199 ALPHA-AMYLASES FROM EXIGUOBACTERIUM, AND METHODS OF USE, THEREOF
Disclosed are compositions and methods relating to alpha-amylase from Exiguobacterium. The compositions and methods are useful, for example, for starch...
2016/0160198 MUTANT ENDONUCLEASE V ENZYMES AND APPLICATIONS THEREOF
Provided herein are mutant endonuclease V enzymes that are capable of nicking an inosine-containing DNA sequence. Nucleic acid assays and agents that employ...
2016/0160197 Compositions and Methods Comprising a Lipolytic Enzyme Variant
The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more...
2016/0160196 Polypeptides with Lipase Activity And Polynucleotides Encoding Same
The present invention relates to isolated polypeptides with lipase activity, selected from the group consisting of: (a) a polypeptide having at least 80%, at...
2016/0160195 ANTI-COCAINE COMPOSITIONS AND TREATMENT
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly...
2016/0160194 RECOMBINANT REVERSE TRANSCRIPTASES
The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H...
2016/0160193 Fusion Polymerase and Method for Using the Same
This disclosure provides, among other things, a composition comprising: comprising a fusion protein comprising: (a) a DNA polymerase; and (b) a heterologous...
2016/0160192 DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
Disclosed are mutant DNA polymerases having increased 3'-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are...
2016/0160191 DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
Disclosed are mutant DNA polymerases having increased 3'-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are...
2016/0160190 DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
Disclosed are mutant DNA polymerases having increased 3'-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are...
2016/0160189 Truncated Constructs of RIPK3 and Related Uses
The invention provides methods and compositions for inducing necroptosis in target cells, including for example cancer cells. This invention provides...
2016/0160188 PEG-Urate Oxidase Conjugates and Use Thereof
A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG),...
2016/0160187 KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS
The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of .alpha.-chloroalcohols from ...
2016/0160186 THERAPEUTIC PHAGES AND METHODS FOR DELIVERY OF NUCLEIC ACIDS FOR THERAPEUTIC USES
Compositions for a phage particle are disclosed. The phage particle is non-replicating and includes at least one heterologous nucleic acid sequence that is...
2016/0160185 CELL MASS CAPABLE OF SERVING AS A PRIMITIVE ORGAN-LIKE STRUCTURE COMPRISED OF A PLURALITY OF CELL TYPES OF...
The present invention provides a method of producing a cell mass capable of serving as a primitive organ-like structure comprised of a plurality of somatic...
2016/0160184 METHODS FOR REPROGRAMMING CELLS AND USES THEREOF
Described herein are reprogrammed cells, and methods for cell dedifferentiation, transformation and eukaryotic cell reprogramming. Also descried are cells,...
2016/0160183 COMPOSITION FOR MAINTAINING CHROMOSOMAL STABILITY OF PLURIPOTENT STEM CELLS, CONTAINING SMALL-MOLECULE COMPOUND
The present invention relates to a composition for maintaining the chromosomal stability of pluripotent stem cells, which contains a small-molecule compound,...
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