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Patent # Description
2016/0166695 RAPID-ACTING INSULIN COMPOSITIONS
The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the...
2016/0166694 PHARMACEUTICAL COMPOSITION, METHOD OF PREPARATION AND METHODS OF TREATING ACHES/PAINS
Provided are methods and compositions useful for treating/aches and/or pains. The compositions include ibuprofen in a clear stable aqueous system of water,...
2016/0166693 RADIATION ENHANCED MACROMOLECULAR DELIVERY OF THERAPEUTIC AGENTS FOR CHEMOTHERAPY
Described herein are anti-cancer compounds composed of a macromolecule comprising (1) at least one anti-cancer agent directly or indirectly bonded to the...
2016/0166692 RNA-CODED ANTIBODY
The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of...
2016/0166691 RNA-CODED ANTIBODY
The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of...
2016/0166690 RNA-CODED ANTIBODY
The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of...
2016/0166689 Subcutaneous anti-HER2 Antibody Formulations and Uses Thereof
The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g....
2016/0166688 COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH BENDAMUSTINE
The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with bendamustine for the treatment of cancer, especially to...
2016/0166687 DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE
The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a ...
2016/0166686 MINI-INTRONIC PLASMID DNA VACCINES IN COMBINATION WITH LAG3 BLOCKADE
It is disclosed herein that (a) an anti-tumor DNA vaccine delivered using a MIP DNA vector is a less effective tumor treatment than the corresponding...
2016/0166685 COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND PD-1 AXIS BINDING ANTAGONISTS
The invention provides compositions and methods for treating cancers. The method comprises administering a PD-1 axis binding antagonist and an OX40 binding...
2016/0166684 Treatment of Fibrotic Diseases
The present invention relates to RSPO and LGR antagonists, and methods of using the RSPO and LGR antagonists for treating or preventing fibrotic diseases.
2016/0166683 ADJUVANT IMMUNOTHERAPY FOR THE TREATMENT CANCER, OF CLINICAL MANIFESTATIONS ASSOCIATED WITH THE DISEASES LIKE...
A compound for use in a method of treatment of cancer, including precancerous lesions, and adverse events caused by the disease or anti-cancer agents and...
2016/0166682 Treatment of Infection
The invention relates to compositions including a substance useful as an adjuvant for potentiating an immune response, and methods of using the composition in...
2016/0166681 TOLL-LIKE RECEPTOR AGONISTS
Compounds described herein can be used for therapeutic purposes. The compounds can be TLR agonists, such as TLR7 or TLR8 agonists. The compounds can be...
2016/0166680 CD200 INHIBITORS AND METHODS OF USE THEREOF
The present invention provides in certain embodiments conjugates comprising at least one CD200 inhibitor and an adjuvant, and methods of reversing or...
2016/0166679 METHOD OF TREATMENT USING FOLATE CONJUGATES AND TYROSINE KINASE INHIBITORS
The invention relates to a method of treating a cancer, the method comprising the steps of administering to a patient an immunogen conjugate, administering to...
2016/0166678 COMBINATION VACCINE
The present invention relates to a vaccine, especially a combination vaccine providing at least a first and a second antigenic function, the combination...
2016/0166677 COMPUTATIONALLY OPTIMIZED BROADLY REACTIVE ANTIGENS FOR H1N1 INFLUENZA
Described herein is the generation of optimized H1N1 influenza HA polypeptides for eliciting a broadly reactive immune response to H1N1 influenza virus...
2016/0166676 Use of Immune Suppressive Peptides as Adjuvants
The present invention relates to an adjuvant comprising at least one immunosuppressive domain for use in a vaccine.
2016/0166675 EV71 VIRUS-LIKE PARTICLES AND PREPARATION METHOD AND APPLICATION THEREOF
The present invention provides EV71 virus-like particles and a preparation method and application thereof. The method comprises: connecting a P1 protein gene...
2016/0166674 VACCINES FOR SEROGROUP X MENINGOCOCCUS
A method for immunising a subject against serogroup X meningococcus by administering a vaccine comprising one, two or all three of: (i) a meningococcal fHbp...
2016/0166673 STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful...
2016/0166672 Atoxic recombinant holotoxins of Clostridium difficile as immunogens
Compositions, methods and kits are provided for preparing an atoxic C. difficile protein that elicits an immune response in the subject specific for TcdA and...
2016/0166671 Clostridium Difficile Compositions and Methods of Use
Fusion proteins include full-length flagellin or portions of flagellin fused to at least one Clostridium difficile antigen. Fusion proteins can include a first...
2016/0166670 COMPOSITIONS OF VACCINES AND ADJUVANTS AND METHODS FOR THE TREATMENT OF URINARY TRACT INFECTIONS
This invention describes novel adjuvant compositions and formulations with excellent stability at refrigerated and room temperatures and up to and about...
2016/0166669 ANTIGENIC COMPOSITIONS AND METHODS
Multilayer films comprised of polypeptide epitopes and a toll-like receptor ligand. The multilayer films are capable of eliciting an immune response in a host...
2016/0166668 COMPOSITION AND VACCINE FOR TREATING PROSTATE CANCER
The present invention relates to a composition comprising at least one mRNA encoding a combination of antigens capable of eliciting an (adaptive) immune...
2016/0166667 DIVALENT VACCINE COMPOSITIONS AND THE USE THEREOF FOR TREATING TUMORS
The invention describes vaccine compositions combined in the same proportion with the extracellular domains of growth factor receptors Her1 and Her2 or...
2016/0166666 TUMOR ANTIGEN PEPTIDE
Provided is a tumor antigen peptide and the like that is useful in the prevention and/or treatment of cancer. The present invention pertains to: a peptide...
2016/0166665 CELLULAR IMMUNITY INDUCING VACCINE
A novel vaccine that can induce sufficiently high cell-mediated immunity is disclosed. The vaccine of the present invention contains, as an effective...
2016/0166664 COMPOSITIONS AND METHODS FOR INDUCTION OF ANTIGEN-SPECIFIC TOLERANCE
The present invention utilizes carrier particles to present antigen peptides and proteins to the immune system in such a way as to induce antigen specific...
2016/0166663 Vaccine Formulations That Induce A TH2 Immune Response
The present invention relates to compositions and methods for the prevention and treatment of neurodegenerative diseases, such Alzheimer's disease, that are...
2016/0166662 USE OF ATTENUATED STRAINS OF PARASITES FOR THE PREVENTION OR TREATMENT OF PATHOLOGIES ASSOCIATES WITH AN...
Strains of Sarcocystidae selected from Toxoplasma spp or Neospora spp isolated from their natural environment and having an immunostimulant effect, for the use...
2016/0166661 ANTIBODY-MEDIATED ANTI-TUMOR ACTIVITY INDUCED BY REISHI MUSHROOM POLYSACCHARIDES
Immunogenic compositions, cancer vaccines and methods for treating cancer comprising FMS, the fucose-enriched polysaccharide fraction from Reishi F3, are...
2016/0166660 COMBINATION THERAPY USING A FACTOR XII INHIBITOR AND A C-1 INHIBITOR
Methods and compositions are disclosed for treating disorders of the contact activation system, comprising the administration of at least one C1-Inhibitor...
2016/0166659 DIGESTIVE ENZYME COMPOSITION SUITABLE FOR ENTERAL ADMINISTRATION
The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional...
2016/0166658 THERAPEUTIC INTERVENTION
Provided are methods and materials for treating a neurological, behavioural, psychological, psychiatric, or personality disorder or syndrome in an individual,...
2016/0166657 Factor IX Polypeptides and Methods of Use Thereof
The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; chimeric and...
2016/0166656 Compositions and Methods for Treating Celiac Sprue Disease
The invention provides compositions and methods for treating celiac sprue.
2016/0166655 HEMOSTATIC COMPOSITIONS
The invention relatesto a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or...
2016/0166654 COLLAGEN-TARGETED NANOPARTICLES
This invention relates to compositions comprising collagen binding peptides coupled to nanoparticles. The invention also relates to a method of imaging a...
2016/0166653 CHEMICALLY AND THERMODYNAMICALLY STABLE INSULIN ANALOGUES AND IMPROVED METHODS FOR THEIR PRODUCTION
The subject matter of this invention is directed towards chemically and thermodynamically stable single-chain insulin (SCI) analogues that are resistant to...
2016/0166652 NOVEL N- AND C-TERMINAL SUBSTITUTED ANTAGONISTIC ANALOGS OF GH-RH
There is provided a novel series of synthetic analogs of hGH-RH(1-29)NH.sub.2 (SEQ ID NO: 1) and hGH-RH(1-30)NH.sub.2. Of particular interest are those...
2016/0166651 SYSTEMIC DELIVERY OF VIRUS VECTORS ENCODING UROCORTIN-2 AND RELATED GENES TO TREAT DIABETES-RELATED CARDIAC...
In alternative embodiments, provided are methods for treating, ameliorating or protecting (preventing) congestive heart failure (CHF) or a diabetes-related...
2016/0166650 THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG...
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
2016/0166649 USE OF HEPCIDIN AS A REGULATOR OF IRON HOMEOSTASIS
The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders...
2016/0166648 Treatment of Multiple Sclerosis With Combination of Laquinimod and Interferon-Beta
This invention provides a method of treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering...
2016/0166647 Pegylated Interleukin-10
Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for...
2016/0166646 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE...
The present invention relates to methods and pharmaceutical compositions for the treatment of acute exacerbation of chronic obstructive pulmonary disease. In...
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