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Patent # Description
2016/0177393 LAFORA'S DISEASE GENE
A novel gene (EPM2B) that is mutated in humans and dogs with Lafora's disease is described.
2016/0177392 METHODS FOR MEASURING VIRULENCE IN SOYBEAN CYST NEMATODE
Phytoparasitic nematodes that are able to infect and reproduce on plants that are considered resistant are referred to as virulent. The mechanism(s) that...
2016/0177391 ANALYSIS FOR TAKOTSUBO CARDIOMYOPATHY BY MEANS OF DIFFERENTIALLY REGULATED MICRORNA MOLECULES
The invention provides an analytical method suitable for detecting the presence of Takotsubo-cardiomyopathy (TTC), especially for differentiating TTC from...
2016/0177390 GENETIC AND IMAGE BIOMARKETS ASSOCIATED WITH DECLINE IN COGNITIVE MEASURES AND BRAIN GLUCOSE METABOLISM IN...
The present disclosure is based on the identification of biomarkers of combined genetic variants and imaging measurements, in predicting faster decline in...
2016/0177389 FUS/TLS-BASED COMPOUNDS AND METHODS FOR DIAGNOSIS, TREATMENT AND PREVENTION OF AMYOTROPHIC LATERAL SCLEROSIS...
The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and...
2016/0177388 POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS
The present disclosure relates to new compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic...
2016/0177387 NOVEL ELECTROCHEMICAL DNA BIOSENSOR USING GRAPHENE BIOCHIP FOR SPECIES IDENTIFICATION
This study describes about a new electrochemical biosensor using DNA-redox electrostatic interaction and their subsequent non-specific adsorption on graphene...
2016/0177386 CALIBRATION PANELS AND METHODS FOR DESIGNING THE SAME
A method for preparing a homopolymer recalibration panel includes: extracting, from a set of amplicons used in sequencing-by-synthesis, a set of candidate...
2016/0177385 HIGH DATA RATE INTEGRATED CIRCUIT WITH POWER MANAGEMENT
A sensor device includes a sensor array and a flow cell in fluid communication with the sensor array. Bias circuitry apply bias arrangements to the sensor...
2016/0177384 SEQUENCING SYSTEMS WITH TWO SLOW-STEP POLYMERASE ENZYMES
Systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the...
2016/0177383 NANOCHANNEL WITH INTEGRATED TUNNEL GAP
A device for electronic sequencing of polymers consisting of a tunnel gap that is self-aligned with a nanochannel.
2016/0177382 DEVICES AND METHODS FOR CONTROLLING REVERSIBLE CHEMICAL REACTIONS AT SOLID-LIQUID INTERFACES BY RAPID...
Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces are disclosed. In particular, the invention relates to a method of...
2016/0177381 Base-Pair Specific Inter-Strand Locks for Genetic and Epigenetic Detection
A versatile detection method is disclosed that utilizes a base-pair-specific inter-strand lock for genetic and epigenetic detection. Reagents, devices, etc.,...
2016/0177380 COMPOSITIONS FOR RNA-CHROMATIN INTERACTION ANALYSIS AND USES THEREOF
The invention described herein provides reagents (e.g., kits), compositions, and methods for carrying out an unbiased genome-wide strategy to identify the...
2016/0177379 DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus. The tests are particularly useful for...
2016/0177378 METHOD FOR SIMULTANEOUS DETECTION OF BACTERIA AND FUNGI IN A BIOLOGICAL PREPARATION BY PCR, PRIMERS AS WELL AS...
An exemplary embodiment describes a method for detection of bacteria and fungi in a sample of biological material, wherein the DNA contained in the sample of...
2016/0177377 COMPOSITIONS AND METHODS FOR DETECTION OF DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
Methods for the rapid detection of the presence or absence of Mycobacterium tuberculosis (MTB) resistant to rifampicin (MTB-RIF) and/or MTB resistant to...
2016/0177376 DETECTION METHOD OF MICRO-RNA WITH HIGH SPECIFICITY
The invention provides a method for detecting miRNA based on polymerase chain reaction comprising EvaGreen dye, and the use of EvaGreen dye in elevating the...
2016/0177375 METHODS AND SYSTEMS FOR DETECTING BIOLOGICAL COMPONENTS
Methods for the detection of components from biological samples are provided. In certain aspects, the methods may be used to detect and/or quantify specific...
2016/0177374 Integrated Capture and Amplification of Target Nucleic Acid for Sequencing
The invention provides efficient methods of preparing a target nucleic acid in a form suitable for sequencing. The methods are particularly amenable for...
2016/0177373 POLYMERASE COMPOSITIONS AND METHODS OF MAKING AND USING SAME
The present disclosure provides compositions, methods, kits, systems and apparatus that are useful for nucleic acid polymerization. In particular, modified...
2016/0177372 ALLELE-SPECIFIC AMPLIFICATION OF NUCLEIC ACIDS USING BLOCKING OLIGONUCLEOTIDES FOR WILD TYPE SUPPRESSION
A method is provided for allele-specific amplification, utilizing a blocking oligonucleotide including at least one nucleotide with a base covalently modified...
2016/0177371 METHOD OF PRETREATMENT OF SAMPLE FOR QUANTITATING CHOLESTEROL AND METHOD FOR QUANTITATING CHOLESTEROL IN...
A method of a pretreatment of a sample for quantitating cholesterol characterized by, before measuring cholesterol contained in specific lipoproteins, treating...
2016/0177370 METHOD FOR DETECTING STREPTOCOCCUS AGALACTIAE USING ESTERASE ACTIVITY
A reaction medium that includes (i) an esterase enzyme substrate that Streptococcus agalactiae is not capable of using at less than 18 hours after inoculation,...
2016/0177369 Resonance Energy Transfer Assay with Cleavage Sequence and Spacer
A molecular construct comprises a donor label, an acceptor label, a linker peptide disposed between the donor and the acceptor, the linker having a cleavage...
2016/0177368 SELECTIVE ENRICHMENT MEDIUM FOR CARBAPENEM-RESISTANT BACTERIA
The present invention relates to a method for direct detection and differentiation of carbapenem-resistant bacteria in a sample comprising (i) inoculation with...
2016/0177367 MICROSENSOR
The present invention relates to a miniature device for detecting, identifying and/or quantifying microorganisms in a sample. The device comprises a surface...
2016/0177366 HAND-HELD MICRO-RAMAN BASED DETECTION INSTRUMENT AND METHOD OF DETECTION
A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various...
2016/0177365 Substance Measurement Method and Measurement Device Employing Electrochemical Biosensor
A method is provided for measuring a substance using a biosensor, the method comprising: introducing a sample containing the substance into an...
2016/0177364 METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES
The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of...
2016/0177363 PROCESSES FOR PREPARING TUBULYSINS
Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for...
2016/0177362 Serum-free Stable Transfection and Production of Recombinant Human Proteins in Human Cell Lines
The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free...
2016/0177361 METHODS OF CULTURING A MAMMALIAN CELL
Provided herein are methods of culturing a mammalian cell in a liquid medium including poloxamer-188 at a concentration of 1.8 g/L or at a greater...
2016/0177360 MICROORGANISMS FOR DITERPENE PRODUCTION
The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl...
2016/0177359 METHOD FOR CONTROLLED DNA FRAGMENTATION
A composition and method for controlled in vitro fragmentation of nucleic acids. A transposase forms catalytically active complexes with a modified transposon...
2016/0177358 PROCESSING BIOMASS
Methods are provided for reducing one or more dimensions of individual pieces of biomass; treating biomass, such as size-reduced biomass; changing a molecular...
2016/0177357 METHOD FOR PRETREATING CELLULOSE-CONTAINING BIOMASS, METHOD FOR PRODUCING BIOMASS COMPOSITION FOR...
A pretreatment method for producing sugar from a cellulose-containing biomass, which includes subjecting the cellulose-containing biomass to hydrothermal...
2016/0177356 NOVEL USE OF MALTOTRIOSYL TRANSFERASE
The present invention is intended to provide a novel use of a maltotriosyl transferase. The present invention provides a method for producing rice cakes or...
2016/0177355 OLIGOSACCHARIDE COMPOSITIONS, GLYCOPROTEINS AND METHODS TO PRODUCE THE SAME IN PROKARYOTES
Disclosed are methods and compositions to produce various oligosaccharide compositions and glycoproteins. Prokaryotic hosts cells are cultured under conditions...
2016/0177354 ENZYMATIC TRANSAMINATION OF CYCLOPAMINE ANALOGS
Provided are processes for the synthesis of amino analogues from ketone starting materials.
2016/0177353 BIOLOGICAL PRODUCTION OF ORGANIC COMPOUNDS
Methods of producing ethylene oxide and ethylene glycol are disclosed herein. Ethylene produced by cyanobacteria engineered to express ethylene-forming enzymes...
2016/0177352 MICROORGANISM FOR METHIONINE PRODUCTION WITH IMPROVED METHIONINE SYNTHASE ACTIVITY AND METHIONINE EFFLUX
The present application is related to a recombinant microorganism optimised for the fermentative production of methionine and/or its derivatives, wherein in...
2016/0177351 MICROORGANISM FOR METHIONINE PRODUCTION WITH ENHANCED METHIONINE EFFLUX
The present invention is related to a recombinant Escherichia coli (E. coli) strain optimised for the fermentative production of methionine and/or its...
2016/0177350 Processes and Systems for Catalytic Manufacture of Wax Ester Derivatives
Processes for transesterifying wax esters. Implementations may include providing a feedstock including wax esters, introducing into the feedstock an alcohol...
2016/0177349 Processes and Systems for Catalytic Manufacture of Wax Ester Derivatives
Processes for transesterifying wax esters. Implementations may include: providing a feedstock including wax esters, contacting the feedstock with a lipase, and...
2016/0177348 RECOMINANT RALSTONIA EUTROPHA CAPABLE OF PRODUCING POLYLACTIC ACID OR POLYLATIC ACID POLYMER, AND METHOD FOR...
Provided are a recombinant Ralstonia eutropha capable of producing polylactate or a hydroxyalkanoate-lactate copolymer, and a method of preparing polylactate...
2016/0177347 YEAST CELL-PRODUCING LACTATE WITH REDUCED ACTIVITY OF RIM15 AND IGO2, METHOD OF PRODUCING THE YEAST CELL, AND...
A yeast cell capable of producing lactate, a method of preparing the yeast cell, and a method of producing lactate by using the yeast cell, wherein theyeast...
2016/0177346 METHOD FOR TREATING SUGAR SOLUTION, HYDROGENATED SUGAR SOLUTION, METHOD FOR PRODUCING ORGANIC COMPOUND, AND...
Provided are a method for treating a saccharide solution, which comprises subjecting a saccharide solution containing at least one selected from the group...
2016/0177345 RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
Systems and methods for the production of malonate in recombinant host cells.
2016/0177344 METHOD AND APPARATUS FOR CO2 SEQUESTRATION
Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO.sub.2 in...
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