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Patent # Description
2016/0177293 MODIFIED PEPTIDE DISPLAY
The invention provides a replicable genetic package displaying a cyclic peptide having at least one intramolecular bond between amino acid side chains. Also...
2016/0177292 METHOD FOR SCREENING CATALYTIC PEPTIDES USING PHAGE DISPLAY TECHNOLOGY
A method for screening catalytic peptides using phage display technology is disclosed. A compound is exposed to a phage library. If a peptide in the library...
2016/0177291 Method and Device for Preparing a Sample of Biological Material Containing Target Cells and Accompanying Cells...
A method for preparing a sample of biological materials containing target cells and accompanying cells for extracting nucleic acids of the target cells...
2016/0177290 METHODS AND COMPOSTIONS FOR TARGETED GENOMIC DELETION
Disclosed herein are compositions and methods for generating chromosomal translocations and targeted deletions of specific lengths and at specific locations...
2016/0177289 REACTION MIXTURES
The present invention provides stable dried reaction mixtures, methods for their preparation, methods for their use, and kits comprising them. The stable dried...
2016/0177288 METHOD FOR PRODUCING ALPHA-SANTALENE
The present invention provides a method of producing .alpha.-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In...
2016/0177287 Purification of Cystathionine Beta-Synthase
This invention provides chromatographic methods for the purification of a cystathionine .beta.-Synthase (CBS) protein, particularly truncated variants thereof...
2016/0177286 GLA-DOMAINLESS FACTOR X
The present invention relates to a protein consisting of the sequence SEQ ID No.: 11 or 25 or 26, directly bound, or bound via a linker, especially ...
2016/0177285 NOVEL MEANS TO DECREASE THE NEGATIVE EFFECTS OF SMOKING
The present invention relates to the use of an elastase inhibitor, preferably fahsin for the treatment or prevention of emphysema, COPD or lung cancer. The...
2016/0177284 CELL-TARGETED MOLECULES COMPRISING AMINO-TERMINUS PROXIMAL OR AMINO-TERMINAL SHIGA TOXIN A SUBUNIT EFFECTOR REGIONS
The present invention provides cell-targeted molecules comprising binding regions for cell-type specific targeting and Shiga toxin A Subunit effector regions...
2016/0177283 HETEROLOGOUS EXPRESSION OF TERMITE CELLULASES IN YEAST
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be...
2016/0177282 Polypeptides Having Cellobiohydrolase I Activity and Polynucleotides Encoding Same
The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the...
2016/0177281 VARIANT ENZYMES
Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the...
2016/0177280 Alpha-Amylase Variants and Polynucleotides Encoding Same
The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs,...
2016/0177279 NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF
The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and...
2016/0177278 Cas9-DNA Targeting Unit Chimeras
The present invention provides a Cas9 platform to facilitate single-site nuclease gene editing precision within a human genome. For example, a Cas9...
2016/0177277 MUTANTS OF COCAINE ESTERASE
Provided are mutant cocaine esterase polypeptides and PEGylated formulations thereof.
2016/0177276 SIRP-ALPHA IMMUNOGLOBULIN FUSION PROTEINS
The invention discloses immunoglobulin fusion proteins designed to bind both CD47 and a tumor cell antigen. The immunoglobulin fusion proteins include a...
2016/0177275 PHOTOBACTERIUM SP. ALPHA-2-6-SIALYLTRANSFERASE VARIANTS
The present invention provides Photobacterium sp. JH-ISH-224 .alpha.2-6-sialyltransferase Psp26ST variants and expression cassettes, vectors, and host cells...
2016/0177274 Bacteria Engineered to Treat Diseases Associated with Hyperammonemia
Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating disorders associated with hyperammonemia are...
2016/0177273 STEM CELLS FOR MODELING TYPE 2 DIABETES
The invention provides stem cell derived beta-pancreatic cells and animal models of T2D in which cells have been grafted. The stem cells bear a mutated form of...
2016/0177272 METHOD FOR SCREENING FOR PLURIPOTENT STEM CELL GROWTH-PROMOTING FACTOR
This invention relates to a method for screening for a growth-promoting factor for pluripotent stem cells with a conditioned medium which is generated by...
2016/0177271 COMBINATIONAL USE OF MECHANICAL MANIPULATION AND PROGRAMIN TO GENERATE PLURIPOTENT STEM CELLS FROM SOMATIC CELLS
The present invention provides methods and compositions for inducing pluripotency in differentiated mammalian cells. In particular, the methods include...
2016/0177270 METHOD FOR INTEGRATING BIOLOGICAL TISSUES WITH A VASCULAR SYSTEM
The present invention provides a method of constituting a tissue construct in vitro using a tissue without depending on scaffold materials. A method of...
2016/0177269 METHODS FOR GENERATING STEM CELL-DERIVED BETA CELLS AND METHODS OF USE THEREOF
Disclosed herein are methods for generating SC-.beta. cells, and isolated populations of SC-.beta. cells for use in various applications, such as cell therapy.
2016/0177268 METHODS FOR GENERATING AUGMENTED STEM CELL-DERIVED BETA CELLS AND USES THEREOF
Disclosed herein are methods for generating augmented SC-.beta. cells, and isolated populations of augmented SC-.beta. cells for use in various applications,...
2016/0177267 SERUM-FREE IN VITRO DIRECTED DIFFERENTIATION PROTOCOL FOR GENERATING STEM CELL-DERIVED BETA CELLS AND USES THEREOF
Disclosed herein are methods for generating SC-.beta. cells using chemically defined, completely serum free media, and isolated populations of SC-.beta. cells...
2016/0177266 MUSCLE STEM CELL IN VITRO CULTURE METHOD AND APPLICATION
Provided is a muscle stem cell in vitro culture method. A muscle stem cell is cultivated in vitro by using a cell culture medium of a cell factor added with a...
2016/0177265 METHOD FOR PRODUCING MEGAKARYOCYTES, PLATELETS AND/OR THROMBOPOIETIN USING MESENCHYMAL CELLS
Provided is a megakaryocyte and/or platelet production method, enabling to produce a megakaryocyte and/or platelet from mesenchymal cells such as preadipocytes...
2016/0177264 METHOD AND SYSTEM FOR THE AUTOMATED PROCESSING OF BIOLOGICAL FLUID DURING LOW LEVEL ALERT CONDITION
Methods and systems for processing biological fluid are disclosed. The methods and systems allow for processing of biological fluid to continue in the event...
2016/0177263 METHODS AND SYSTEMS FOR PRIMING A BIOLOGICAL FLUID PROCESSING CIRCUIT
Methods and systems for priming biological fluid processing systems are disclosed. In accordance with such methods and systems, the disposable fluid processing...
2016/0177262 METHODS FOR CELL WASHING WITH ON-LINE DILUTION OF CELL FEED
Systems and methods for the washing of biological fluid/biological cells are disclosed. The method provides for the automated dilution of the cell feed during...
2016/0177261 METHODS OF INDUCING AND PREVENTING NEUROFIBROMATOSIS IN SCHWANN CELLS
The invention provides a method of inducing neurofibromatosis type 2 (NF2) in Schwann cells. The method comprises contacting the cells with laminin-1 so as to...
2016/0177260 METHOD FOR PRODUCING DOPAMINERGIC NEURONS
The present invention provides a method of more efficiently producing a high-quality dopaminergic neuron from neural progenitor cells, specifically, a...
2016/0177259 ACETOGENIC BACTERIA
A method of culturing at least one acetogenic bacteria, includes growing the bacteria in an aqueous medium comprising an amount of cysteine and/or cystine,...
2016/0177258 BIOMASS PRODUCTION
A process of growing a phototrophic biomass in a reaction zone, including a reaction mixture that is operative for effecting photosynthesis upon exposure to...
2016/0177257 OPTIMISED METHOD FOR BREAKING CHLORELLA CELL WALLS BY MEANS OF VERY HIGH PRESSURE HOMOGENISATION
Disclosed is an optimized method for breaking the cell walls of microalgae of the Chlorella genus, more particularly Chlorella vulgaris, Chlorella sorokiniana...
2016/0177256 METHOD FOR MANUFACTURING AN ACTIVE SUBSTANCE FOR INDUCING SELF-LYSIS IN MICROALGA CELLS, ACTIVE SUBSTANCE...
The disclosure provides a method for manufacturing an active substance for inducing self-lysis in microalga cells, including: inoculating a bacterial strain...
2016/0177255 LABYRINTHULOMYCETE STRAINS FOR PRODUCING DOCOSAHEXAENOIC ACID
Improved labyrinthulomycetes strains that produce microbial oils having increased docosahexaenoic acid (DHA) content are disclosed. The strains have increased...
2016/0177254 CELL PICKING SUPPORT DEVICE, DISPLAY DEVICE AND CULTURE CONTAINER
A cell picking support device, a display device and a culture container that can enhance work efficiency. An adapter fixes a well plate that holds cells...
2016/0177253 METHOD AND SYSTEM FOR PREPARATION OF SUBSTRATE FOR USE IN ANAEROBIC DIGESTION OF ORGANIC WASTE
There is disclosed a method for preparation of substrate for use in anaerobic digestion of organic waste. The method can be executed in a substrate...
2016/0177252 REMOVAL OF MICROORGANISMS FROM CELL CULTURE MEDIA
Compositions and methods are provided for removing viral contaminants from a chemically defined cell culture medium. Compositions provided herein are resistant...
2016/0177251 Microbial Electro-Photosynthesis
Methods and apparatus for growing photosynthetic organisms lacking Photosystem II (PSII) function using externally supplied electrons shuttled into the...
2016/0177250 TISSUE TRANSFER SYSTEM
Described herein are devices for the transfer of tissue into tissue processing devices. In some embodiments, the devices provide for the transfer of tissue...
2016/0177249 Reactor System
An apparatus is described which includes at least one reactor, at least one linear piston pump, the or each piston pump including a tube, a piston and an arm...
2016/0177248 PIVOTING PRESSURIZED SINGLE USE BIOREACTOR
Pressurized hermetically sealed bags disposed inside a cylindrical support and containing a septum with variable density of porosity and dividing the bag into...
2016/0177247 GAS PERMEABLE MATERIAL
The invention describes a gas permeable fluoropolymer and silicone material used in the construction of cell culture bags.
2016/0177246 SYSTEM FOR CULTURE OF CELLS IN A CONTROLLED ENVIRONMENT
A cell culture container is provided, comprising membrane bound compartments for growing and harvesting monocytes that allows replenishing and removal of feed...
2016/0177245 T-CELL CULTURE DOUBLE BAG ASSEMBLY
A cell culture bag is provided, comprising a framed porous inner fluoropolymer bag that allows for growing and harvesting cells and an outer fluoropolymer bag...
2016/0177244 AUTOMATED CELL CULTURE SYSTEM AND METHOD
An automated method for culturing stem cells using a robotic liquid handling system including a translatable bed and a movable multichannel pipette. The method...
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