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Patent # Description
2016/0175442 Systems, Methods, and Compositions For Cross-Linking Treatments of an Eye
Systems, methods, and compositions generate cross-linking activity for treatment of eye disorders. Various agents, additives, buffers, etc., may be employed in...
2016/0175441 COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) ANTIBODIES AS AN ENHANCER OF IMMUNE RESPONSE
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium....
2016/0175440 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BURKHOLDERIA INFECTIONS
Methods for breaking down biofilms in cystic fibrosis patients are disclosed.
2016/0175439 VEGF ANTAGONIST FORMULATIONS
Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a...
2016/0175438 USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMAB
The present application describes uses for Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for...
2016/0175437 PROTEIN
The present invention provides methods and compositions for screening, diagnosis and prognosis of colorectal cancer, kidney cancer, liver cancer, lung cancer,...
2016/0175436 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects...
2016/0175435 TREATMENT OF PEMPHIGUS
The present invention concerns treatment of pemphigus with an antibody which binds to CD20.
2016/0175434 METHODS OF TREATING PRE-ECLAMPSIA OR ECLAMPSIA
Disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1...
2016/0175433 LIPIDATED IMMUNE RESPONSE MODIFIER COMPOUND COMPOSITIONS, FORMULATIONS, AND METHODS
The compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxyl}butyl)octadeca- namide is a useful drug compound for enhancing immune response and can...
2016/0175432 AN OIL-IN-WATER EMULSION CONTAINING NO SURFACTANT AND USE THEREOF
The present invention discloses an oil-in-water emulsion containing no surfactant, which comprises a metabolizable oil phase, an aqueous phase and oil-water...
2016/0175431 Vaccine Composition
Disclosed are compositions and the use of the compositions for protection against pathogens comprising an isolated internal pathogenic protein, a TLR agonist...
2016/0175430 MODIFIED POLYSACCHARIDES FOR CONJUGATE VACCINES
The present invention relates to methods of manufacture of immunogenic glycoconjugates, in particular for use in pharmaceutical compositions for inducing a...
2016/0175429 Immunotherapy Composition and Use Thereof
The present invention relates to the field of preventing or reducing incidence or severity of an allergic immune response, and compositions for preventing or...
2016/0175428 VACCINE AND DRUG DELIVERY BY INTRANASAL APPLICATION OF VECTOR AND VECTOR EXTRACTS
Disclosed and claimed is a method of non-invasive immunization in an animal and/or a method of inducing a systemic immune response or systemic therapeutic...
2016/0175427 Influenza Nucleic Acid Molecules And Vaccines Made Therefrom
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA Influenza A of serotype H7N9 alone and in combination with HA...
2016/0175426 COMPOSITIONS FOR MUCUSAL DELIVERY, USEFUL FOR TREATING PAPILLOMAVIRUS INFECTIONS
Polypeptides, compositions, and methods for treatment of papillomavirus (PV) infections including a papillomavirus (PV) minor capsid (L2) polypeptide fragment...
2016/0175425 METHOD FOR RAPIDLY DESIGNING PHARMACEUTICAL PREPARATIONS FOR PREVENTING VIRAL INFECTION
Certain embodiments of the present invention include a method for rapidly designing pharmaceutical preparations for preventing viral infection that have...
2016/0175424 Haemophilus Influenzae Type IV PILI
The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type...
2016/0175423 VACCINE COMPOSITION
The present invention relates to an immuno-protective and non-toxic Gram-negative bleb vaccine suitable for paediatric use. Examples of the Gram-negative...
2016/0175422 COMBINATION NEISSERIAL COMPOSITIONS
Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term...
2016/0175421 GLYCAN CONJUGATES AND USE THEREOF
Described herein are synthetic glycan conjugates comprising a carrier and a glycan moiety derived from Neisseria meningitidis, wherein the glycan moiety is...
2016/0175420 IMMUNOGENIC COMPOSITIONS AGAINST TUBERCULOSIS
Methods of preparing mutants of Mycobacterium tuberculosis with one or more disrupted genes are presented, where the disrupted genes include ctpV, rv0990c,...
2016/0175419 POLYMER PARTICLES AND USES THEROF
The present invention relates to polymer particles and uses thereof. In particular the present invention relates to functionalised polymer particles, processes...
2016/0175418 Ureaplasma Vaccine and Antibodies
The present invention encompasses methods and compositions for Ureaplasma infection prevention and/or treatment. In specific cases, the invention concerns...
2016/0175417 Purified Plasmodium and Vaccine Compositions
Disclosed are substantially purified Plasmodium sporozoites and preparations of Plasmodium sporozoites substantially separated from attendant non-sporozoite...
2016/0175416 ALLOGENEIC TUMOR CELL VACCINATION
The present invention relates to cancer immunotherapy, specifically to allogeneic tumor cell vaccines. According to some embodiments, the invention provides...
2016/0175415 METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines...
2016/0175414 TUMOR ANTIGENS FOR DETERMINING CANCER THERAPY
The present invention relates to the treatment of cancer, in particular breast cancer, particularly triple-negative breast cancer. More particularly, the...
2016/0175413 METHOD AND COMPOSITION FOR TREATING SARCOPENIA
A method of treating sarcopenia comprises immunizing a subject in need thereof against AGE-modified proteins or peptides of a cell. Immunizing a subject...
2016/0175412 PREVENTION OF TYPE 1 DIABETES BY TREG VACCINATION WITH AN INSULIN MIMETOPE
The invention involves methods and products for inducing Treg cells for immune suppression in connection with autoimmune disease and transplant rejection.
2016/0175411 INFANT NUTRITION WITH PROTEASE INHIBITOR
Provided is an infant nutrition comprising at least one protease inhibitor, a process for preparing such an infant nutrition and use of the infant nutrition...
2016/0175410 SUSTAINED RELEASE POLOXAMER CONTAINING PHARMACEUTICAL COMPOSITIONS
A thermo-reversible thermoplastic pharmaceutical composition, comprising a botulinum toxin and a biocompatible poloxamer which provides thermoreversibility to...
2016/0175409 INJECTION PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a...
2016/0175408 DIRECT APPLICATION SYSTEM AND METHOD FOR THE DELIVERY OF BIOACTIVE COMPOSITIONS AND FORMULATIONS
The embodiments relate to improved skin quality, health and appearance using a new delivery method and certain bioactive compositions and formulations. The...
2016/0175407 PROCESS FOR PREPARING A HIGHLY PURE NEUROTOXIC COMPONENT OF A BOTULINUM TOXIN AND USES THEREOF
The present invention relates to a process for preparing a highly pure neurotoxic component of a botulinum toxin by cultivating clostridium botulinum under...
2016/0175406 PRODUCTS AND METHODS FOR DELIVERY OF POLYNUCLEOTIDES BY ADENO-ASSOCIATED VIRUS FOR LYSOSOMAL STORAGE DISORDERS
The present invention relates to methods and materials useful for systemically delivering polynucleotides across the blood brain barrier using adeno-associated...
2016/0175405 FUSION PROTEINS AND METHODS FOR TREATING HIV INFECTION AND AIDS RELATED SYMPTOMS
Pharmaceutical compositions and methods for using a fusion protein having a superoxide dismutase and a transit peptide are described. Pharmaceutical...
2016/0175404 AGENT FOR REDUCING THE USEABLE CALORIE CONTENT OF FOOD AND FOR THERAPEUTIC REDUCTION OF WEIGHT, IN PARTICULAR...
There are disclosed compositions and methods for treating obesity using 5-D-fructose dehydrogenase. Other embodiments are also described.
2016/0175403 SCARRING REDUCING WOUND TREATMENT
Undue scarring of healing wounds is decreased and/or the relapse rate of wounds is lowered by applying a composition that includes hemoglobin to the wound...
2016/0175402 POLYMER-FACTOR VIII MOIETY CONJUGATES
Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a...
2016/0175401 COMPOITIONS AND METHODS FOR MODULATING THERMOGENESIS USING PTH-RELATED AND EGF-RELATED COMPOUNDS
The present invention provides compositions and methods for modulating thermogenesis and related activities by modulating PTH-related and EGF-related...
2016/0175400 METHODS FOR TREATING METABOLIC DISORDERS AND OBESITY WITH GIP AND GLP-1 RECEPTOR-ACTIVE GLUCAGON-BASED PEPTIDES
Methods are provided for administering an extended half-life GLP-1/GIP coagonist peptide to a patient in need thereof for reducing weight gain, inducing weight...
2016/0175399 IL-13 RECEPTOR BINDING PEPTIDES
A targeting peptide that specifically binds to an IL13 receptor (e.g., wherein said targeting peptide is not an IL13 fragment) is described. The targeting...
2016/0175398 Chimeric Immunoreceptor Useful in Treating Human Cancers
The present invention relates to chimeric transmembrane immunoreceptors, named "zetakines," comprised of an extracellular domain comprising a soluble receptor...
2016/0175397 COMBINATION THERAPY OF TUMOR-TARGETED IL-2 VARIANT IMMUNOCYTOKINES AND ANTIBODIES AGAINST HUMAN PD-L1
The present invention relates to the combination therapy of specific tumor-targeted IL-2 variant immunocytokines with specific antibodies which bind human PD-L1.
2016/0175396 METHODS FOR TREATING OR PREVENTING FATTY LIVER DISEASE USING CTRP3
Methods are disclosed for treating or preventing fatty liver disease using a CTRP3 polypeptide or functional variant thereof.
2016/0175395 USE OF OSTEOPROTEGERIN (OPG) TO INCREASE HUMAN PANCREATIC BETA CELL SURVIVAL AND PROLIFERATION
It is disclosed herein that osteoprotegerin increases human beta cell proliferation and survival. Methods are provided for increasing beta cell proliferation,...
2016/0175394 Compositions and Uses of Lectins
The disclosure relates to uses of a purified or isolated lectin to kill bacteria, viruses, and other pathogens. In certain embodiments, the disclosure relates...
2016/0175393 USE OF NUTRITIONAL COMPOSITIONS WITH PHOSPHOLIPID SPHINGOLIPID AND CHOLESTEROL
A nutritional composition comprising phospholipids, sphingolipids and cholesterol for the prevention of obesity and/or diabetes is provided.
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