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Patent # Description
2016/0175342 CONTINUOUS RELEASE COMPOSITIONS MADE FROM HYALURONIC ACID, AND THERAPEUTIC APPLICATIONS OF SAME
The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene...
2016/0175341 HYDROXYALKYL STARCH FOR THE TREATMENT OF HEMATOLOGICAL NEOPLASMS
The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of a hematological neoplasm, especially by...
2016/0175340 POLYSACCHARIDE FOR USE IN PREVENTING METASTASIS FORMATION AND/OR RELAPSE
The present invention relates to a polysaccharide comprising, optionally substituted, monosaccharide units linked via alpha-glycosidic bonds for use in...
2016/0175339 METHODS FOR DETECTING AND MODULATING THE SENSITIVITY OF TUMOR CELLS TO ANTI-MITOTIC AGENTS AND FOR MODULATING...
Provided herein is a method of screening a tumour cell for resistance to a tubulin-binding agent, the method comprising detecting the expression of any one or...
2016/0175338 MARIBAVIR ISOMERS, COMPOSITIONS, METHODS OF MAKING AND METHODS OF USING
The invention relates to novel compositions and methods of using maribavir which enhance its effectiveness in medical therapy, as well as to maribavir isomers...
2016/0175337 TREATMENT OF PAPULOPUSTULAR ROSACEA WITH IVERMECTIN
Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an...
2016/0175336 TRADITIONAL CHINESE MEDICINE COMPOSITION, AND PREPARATION AND APPLICATION THEREOF
A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof,...
2016/0175335 ANTIFUNGAL COMBINATION THERAPY OF TAVABOROLE AND EFINACONAZOLE
A novel combination of two antifungal agents is provided. The combination contains efinaconazole and a boron-containing antifungal agent or salts thereof. The...
2016/0175334 ANTIFUNGAL COMBINATION THERAPY OF TAVABOROLE AND CICLOPIROX
A novel combination of two antifungal agents is provided. The combination contains ciclopirox and a boron-containing antifungal agent or salts thereof. The...
2016/0175333 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING COMPLEX REGIONAL PAIN...
Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. The oral bioavailability...
2016/0175332 FUMAGILLOL DERIVATIVES
Disclosed are compounds of Formula 1, ##STR00001## stereoisomers thereof and pharmaceutically acceptable salts of the compounds and stereoisomers, wherein...
2016/0175331 TREATMENT OF LEUKEMIA WITH ARTEMISININ DERIVATIVES AND COMBINATIONS WITH OTHER ANTINEOPLASTIC AGENTS
Methods of treating cancer, such as leukemia, via administration of therapeutically effective amounts of artemisinins and second agents are detailed herein....
2016/0175330 METHOD OF TREATMENT USING AN ASSOCIATION OF LOSARTAN AND ACETYLSALICYLIC ACID, AND KIT
The present invention relates to a method of treatment comprising administering an association of an antihypertensive agent and antiplatelet agent, wherein the...
2016/0175329 MESALAMINE SUPPOSITORY
A mesalamine rectal suppository having improved comfort of use and better retention in lower rectum for a long period of time is provided. The suppository...
2016/0175328 COMPOSITIONS AND TREATMENTS OF HEART FAILURE IN NON-HUMAN MAMMAL ANIMALS
The invention relates to new compositions comprising an aldosterone antagonist according to a particular posology for the treatment of heart failure in...
2016/0175327 TOMATIDINE, ANALOGS THEREOF, COMPOSITIONS COMPRISING SAME, AND USES FOR SAME
In one aspect, the invention relates to methods for promoting muscle hypertrophy or decreasing adiposity by providing to an animal in need thereof an effective...
2016/0175326 METHOD FOR TREATMENT OF DISEASES
The invention provides a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering a ...
2016/0175325 TRIMEGESTONE (TMG) FOR TREATMENT OF PRETERM BIRTH
As disclosed herein, novel compositions including steroid hormones, such as trimegestone (TMG) and progesterone (P4), provide treatments for term and preterm...
2016/0175324 ANTI-ACNE COMPOSITIONS COMPRISING BILE ACID-FATTY ACID CONJUGATES
Provided are topical pharmaceutical compositions including fatty acid bile acid conjugates (FABACs) as an active ingredient. Further provided are methods of...
2016/0175323 PHARMACEUTICAL COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION AND METHODS FOR FABRICATING THEREOF
Pharmaceutical ophthalmic compositions are described, the compositions consisting essentially of a therapeutically effective quantity of an anti-bacterial...
2016/0175322 Treatment Methods Using Pharmaceutical Solid State Forms
The invention provides and describes solid state 17.alpha.-ethynyl-androst-5-ene-3.beta.,7.beta.,17.beta.-triol including amorphous and crystalline forms and...
2016/0175321 INTRANASAL LOWER DOSAGE STRENGTH TESTOSTERONE GEL FORMULATIONS AND USE THEREOF FOR TREATING ANORGASMIA OR...
The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the...
2016/0175320 COMPOSITIONS, METHODS AND KITS FOR TREATING CANCER
Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: .DELTA..sup.12-prostaglandin...
2016/0175319 COMPOSITION FOR THE TREATMENT OF CYSTIC FIBROSIS
The present invention provides compositions comprising a prostacyclin or prostacyclin analogue, or a pharmaceutically acceptable salt thereof for use in...
2016/0175318 COMPOSITIONS COMPRISING ANTIBACTERIAL AGENT AND TAZOBACTAM
A pharmaceutical composition comprising antibacterial agent and tazobactam, wherein the ratio of tazobactam to the antibacterial agent in the composition is in...
2016/0175317 PHARMACEUTICAL COMPOSITION COMPRISING BRINZOLAMIDE
The present invention provides an improved novel process of manufacturing a sterile, ophthalmic pharmaceutical suspension comprising an active ingredient(s)...
2016/0175316 METHOD OF PREVENTING OR TREATING ORGAN, HEMATOPOIETIC STEM CELL OR BONE MARROW TRANSPLANT REJECTION
Methods of preventing or treating organ, hematopoietic stem cell or bone marrow transplant rejection are disclosed.
2016/0175315 N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel...
2016/0175314 1,2,4-TRIAZINE-4-AMINE DERIVATIVES
According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the...
2016/0175313 ENTECAVIR MICROSPHERES AND PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION CONTAINING SAME
The present invention relates to entecavir microspheres and a pharmaceutical composition for parenteral administration containing the same. The entecavir...
2016/0175312 Use of Inhibitors of Bruton's Tyrosine Kinase (BTK)
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance...
2016/0175311 USE OF PEMIROLAST IN THE TREATMENT OF ACUTE ASTHMA
According to the invention there is provided pemirolast, or a pharmaceutically acceptable salt thereof, for use in the therapeutic treatment of asthma, such as...
2016/0175310 BOOSTING THE EFFECT OF METHOTREXATE THROUGH THE COMBINED USE WITH LIPOPHILIC STATINS
The invention relates to the use of an inhibitor of the dihydrofolate reductase enzyme selected from the group that consists of methotrexate, trimetrexate and...
2016/0175309 POLYMORPHS OF ARRY-380, A SELECTIVE HER 2 INHIBITOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Polymorphs of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dim- ethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided...
2016/0175308 THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS
The present disclosure relates to a therapeutic agent for use in a method for modulating the function and/or growth of a thymus in a subject, wherein the...
2016/0175307 sGC STIMULATORS
Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be...
2016/0175306 COMBINATION OF A IMIDAZOPYRIDAZINE DERIVATIVE AND A MITOTIC AGENT FOR THE TREATMENT OF CANCER
The present invention relates to a combination comprising an Mps-1 kinase inhibitor and a mitotic inhibitor. The present invention also relates to the use of...
2016/0175305 CRYSTALLINE FORMS OF 5-CHLORO-N2-(2-ISOPROPOXY-5-METHYL-4-PIPERIDIN-4-YL-PHENYL)-N4-[2-(PROPAN- ...
The present invention describes specific crystalline forms of 5-chloro-N-(2-isopropoxy-5-methyl-4-(piperidin-4-yl-phenyl)-N-2-(isopropy- ...
2016/0175304 N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS
The present invention relates to N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides of the formula I, ##STR00001## wherein Ar, R1, R2 and n have the...
2016/0175303 SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS
Disclosed are compounds of general formula A useful as potential anti-tubercular agents. The general formula A is ##STR00001##
2016/0175302 MASITINIB FOR TREATING GASTRIC CANCER
The present invention relates to a method for treating gastric cancer in a subject in need thereof, comprising administering to the subject a therapeutically...
2016/0175301 USE OF LEVOCETIRIZINE AND MONTELUKAST TO AMELIORATE INFLAMMATION FOLLOWING RADIATION EXPOSURE
The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of levocetirizine and...
2016/0175300 PROCESS FOR PREPARING OXYCODONE DOCAGE FORM
In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
2016/0175299 METHODS OF TREATING PAIN
In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
2016/0175298 OXYCODONE DOSAGE FORMS
In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
2016/0175297 Morphine Formulations
Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate...
2016/0175296 Method of producing uniform buprenorphine-containing formulations
A method of forming a liquid formulation includes preparing a mixture and adding a second component to the mixture to form the liquid formulation. The mixture...
2016/0175295 COMBINATIONS COMPRISING MABA COMPOUNDS AND CORTICOSTEROIDS
A combination which comprises (a) corticosteroid and (b) a dual muscarinic antagonist-.beta.2 adrenergic agonist compound, or any pharmaceutically acceptable...
2016/0175294 Sustained Release Aminopyridine Composition
A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a...
2016/0175293 PIM KINASE INHIBITOR COMBINATIONS
The present invention relates to a Pim kinase inhibitor compound that can be used alone or in a pharmaceutical combination. One such combination comprises (a)...
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