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Patent # Description
2016/0186269 NOVEL TRANSLOCATIONS IN LUNG CANCER
The invention relates to methods for determining the presence or absence of striatin-anaplastic lymphoma kinase (STRN-ALK) gene fusion and/or a Fibroblast...
2016/0186268 GENE DEFECTS AND MUTANT ALK KINASE IN HUMAN SOLID TUMORS
Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part...
2016/0186267 METHODS, COMPOSITIONS, AND KITS FOR NUCLEIC ACID ANALYSIS
Aspects of the invention relate to methods and kits for assessing cancer. Some aspects of the invention relate to methods and kits for preparing a sample...
2016/0186266 MOLECULAR PROFILING FOR PERSONALIZED MEDICINE
Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to...
2016/0186265 Methods for Typing HLA Alleles
This disclosure relates to the typing of human leucocyte antigen (HLA) alleles. More particularly, the present invention relates to HLA typing as a method of...
2016/0186264 METHODS AND KITS FOR TREATING AND CLASSIFYING INDIVIDUALS AT RISK OF OR SUFFERING FROM TRAP1 CHANGE-OF-FUNCTION
The present disclosure provides methods and kits for treating and classifying individuals at risk of or suffering from a neurological and/or mitochondrial...
2016/0186263 USING PLEXIN-A4 AS A BIOMARKER AND THERAPEUTIC TARGET FOR ALZHEIMER'S DISEASE
The present disclosure provides methods, assays and systems for detecting an increased risk for Alzheimer's disease (AD) in a subject by identifying at least...
2016/0186262 COMPOSITIONS AND METHODS FOR GENETIC ANALYSIS OF EMBRYOS
This disclosure provides compositions and methods for determining a presence or absence of a genomic copy number alteration (CNA) in an embryo, wherein the...
2016/0186261 PREVOTELLA COPRI AND ENHANCED SUSCEPTIBILITY TO ARTHRITIS
Methods, reagents and compositions thereof for predicting risk for NORA onset in susceptible individuals, diagnosing NORA onset, and/or evaluating efficacy of...
2016/0186260 CANCER VACCINATION WITH ANTIGEN EVOLUTION
The invention provides methods for treating with cancer vaccines patients whose cancers undergo clonal evolution. The invention makes use of a series of cancer...
2016/0186259 GENE AND PROTEIN EXPRESSION PROPERTIES OF ADHERENT STROMAL CELLS CULTURED IN 3D
Adherent stromal cells cultured under three dimensional conditions are provided, characterized, and distinguished from adherent stromal cells cultured under...
2016/0186258 DETECTION OF RNA-INTERACTING REGIONS IN DNA
The present invention provides methods and kits for detecting RNA-interacting regions in genomic DNA.
2016/0186257 IDENTIFYING MARKERS OF CALORIC RESTRICTION AND CALORIC RESTRICTION MIMETICS
Markers of caloric restriction (CR) can be identified in a selected tissue by exposing an animal to CR conditions and selecting one or more genes...
2016/0186256 IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a)...
2016/0186255 SUBSTRATES, SYSTEMS AND METHODS FOR ANALYZING MATERIALS
Substrates, systems and methods for analyzing materials that include waveguide arrays disposed upon or within the substrate such that evanescent fields...
2016/0186254 Sequencing Biopolymers
The invention relates to a method and a corresponding arrangement for sequencing at least two biopolymers (6), wherein for each biopolymer (6) a sequence...
2016/0186253 NON-INVASIVE PRENATAL DIAGNOSIS OF FETAL GENETIC CONDITION USING CELLULAR DNA AND CELL FREE DNA
Disclosed are methods for determining at least one sequence of interest of a fetus of a pregnant mother. In various embodiments, the method can determine one...
2016/0186252 PH MEASUREMENT FOR SEQUENCING OF DNA
The present method involves sequencing by synthesis in which a template strand having an attached primer is immobilized in a small volume reaction mixture. In...
2016/0186251 Modified Primers for Nucleic Acid Amplification and Detection
A method of nucleic acid amplification involving using a first modified primer which provides protection to the amplification product from exonuclease...
2016/0186250 MULTIPLEX QUANTITATIVE PCR
Disclosed are methods and compositions for determining the average length or abundance of a first target nucleic by calculating the abundance of a first target...
2016/0186249 TAGGED OLIGONUCLEOTIDES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION METHODS
The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting...
2016/0186248 METHOD FOR CENTRIFUGE MOUNTABLE MANIFOLD FOR PROCESSING FLUIDIC ASSAYS
The disclosure generally relates to a method and apparatus for centrifuge mountable manifold for processing fluid assays. In one embodiment, the disclosure...
2016/0186247 Detection of Chromosomal Inversions
A method and a kit for the identification of chromosomal inversions are described. Chromosomal inversions are difficult to detect unless they are quite large....
2016/0186246 PROCESS FOR DETECTING OR QUANTIFYING NUCLEIC ACIDS IN A LIBRARY
This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes...
2016/0186245 MULTIPLEX DETECTION OF NUCLEIC ACIDS
Methods of detecting nucleic acids, including methods of detecting two or more nucleic acids in multiplex branched-chain DNA assays, are provided. Nucleic...
2016/0186244 Real Time Cleavage Assay
A cleavage-based real-time PCR assay method is provided. In general terms, the assay method includes subjecting a reaction mixture comprising a) PCR reagents...
2016/0186243 LABELED ENZYME COMPOSITIONS, METHODS AND SYSTEMS
Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological...
2016/0186242 COMPOSITIONS AND METHODS FOR DETECTION OF MYCOBACTERIUM AVIUM PARATUBERCULOSIS
Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium...
2016/0186241 BUFFERS FOR THE STABLE STORAGE OF NUCLEIC ACIDS
Provided herein are buffers for the stabilization of nucleic acid molecules. The buffers find particular use for the stabilization of trace amounts of nucleic...
2016/0186240 DEVICES AND METHODS FOR MOLECULAR DIAGNOSTIC TESTING
A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is...
2016/0186239 MULTIPLEXED ASSAY FOR QUANTITATING AND ASSESSING INTEGRITY OF CELL-FREE DNA IN BIOLOGICAL FLUIDS FOR CANCER...
A retrotransposable element based multiplexed qPCR assay to robustly quantitate and distinguish cell free DNA integrity and concentration in blood plasma and...
2016/0186238 REACTIVITY-DEPENDENT AND INTERACTION-DEPENDENT PCR
Methods, reagents, compositions, and kits for reactivity-dependent polymerase chain reaction (RD-PCR) and interaction-dependent polymerase chain reaction...
2016/0186237 METHODS AND COMPOSITIONS TO ENABLE ENRICHMENT OF MINOR DNA ALLELES BY LIMITING DENATURATION TIME IN PCR OR...
The present invention is directed to methods, compositions and reaction mixtures for conducting COLD-PCR, by controlling and varying a preferential...
2016/0186236 REAL TIME QUANTITATIVE AND QUALITATIVE ANALYSIS METHOD FOR BIOSUBSTANCE
A method of quantitatively and qualitatively analyzing a biomaterial in real-time, the method comprising preparing a device for detecting a biomaterial,...
2016/0186235 APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS
Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise...
2016/0186234 CODON-OPTIMIZED GENE FOR MUTATED SHRIMP LUCIFERASE AND METHOD FOR USE THEREOF
There has been a demand for a codon-optimized gene for the mutated catalytic domain of Oplophorus luciferase, which is capable of efficiently expressing a...
2016/0186233 SCREENING METHODS USING FYN IN COMBINATION WITH TAU PROTEIN
The present invention provides materials and methods relating to screening for compounds useful in the treatment of Alzheimer's disease and related conditions....
2016/0186232 MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE...
Provided is a composition by which glycated hemoglobin can be measured even in the presence of a stronger surfactant than a conventional case. Also provided is...
2016/0186231 USE OF A FLUIDIC DEVICE
A fluidic device (1) has a culture chamber (10) configured to house a 3D culture matrix (2) comprising a culture of microorganisms (6). A concentration...
2016/0186230 Enzyme Electrode
The present invention provides an enzyme electrode comprising: an electrode; and a detection layer which is in contact with the electrode, where the detection...
2016/0186229 METHODS AND APPARATUS FOR DETERMINING ANALYTE IN A SAMPLE USING A SENSOR HAVING ELECTRODES WHICH ARE PROVIDED...
The invention relates to a method of and apparatus for determining concentration of an analyte, such as glucose, in a fluid sample, such as body fluid or...
2016/0186228 METHOD FOR THE PRODUCTION OF A GLYCOSYLATED IMMUNOGLOBULIN
Herein is reported a method for the production of an immunoglobulin comprising the following steps: a) providing a eukaryotic cell comprising a nucleic acid...
2016/0186227 METHODS AND COMPOSITIONS FOR PREVENTING NORLEUCINE MISINCORPORATION INTO PROTEINS
The present invention relates to methods and compositions for preventing incorporation of norleucine into proteins during recombinant protein production in...
2016/0186226 METHOD FOR PRODUCING EXTRACELLULAR PROTEINS FROM GENUS TEPIDIMONAS
The disclosure provides a method for producing extracellular proteins from genus Tepidimonas, including: performing a fermentation culturing to a bacteria of...
2016/0186225 METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
2016/0186224 ENHANCED LIGATION REACTIONS
In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of at least one agent that...
2016/0186223 PRODUCTION OF OLIGOSACCHARIDES
The present invention relates to the use of one or more glycosidases in the process for the production and/or purification of a produced desired ...
2016/0186222 FUNGAL XYLANASES AND XYLOSIDASES
The present invention provides fungal xylanase and/or xylosidase enzymes suitable for use in saccharification reactions. The present invention provides...
2016/0186221 COMPOSITIONS AND METHODS OF USE
The present compositions and methods relate to a beta-mannanase from Paenibacillus kribbensis, polynucleotides encoding the beta-mannanase, and methods of make...
2016/0186220 PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF FUNCTIONALIZED FURYL ALCOHOLS
The invention relates to a process for preparing a compound of the formula (I), ##STR00001## in which R is H or C.sub.1-C.sub.6 alkyl, by reaction of at least...
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