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Patent # Description
2016/0184419 RECOMBINANT MYCOBACTERIUM AS A VACCINE
The invention relates to a recombinant Mycobacterium cell for use as a vaccine.
2016/0184418 SWINE DYSENTERY VACCINE
The present invention relates to a composition comprising Brachyspira hyodysenteriae bacteria, particularly in the field of immunization against swine...
2016/0184417 Methods and Compositions for Inhibiting Diseases of the Central Nervous System
Methods and compositions for treating central nervous system diseases and disorders are disclosed.
2016/0184416 Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of...
2016/0184415 COMPOSITIONS FOR AND METHODS OF TREATING AND PREVENTING TARGETING TUMOR ASSOCIATED CARBOHYDRATE ANTIGENS
Compositions useful to induce anti-TACA immune response and kits comprising the same and methods of using the compositions to treat and prevent cancer are...
2016/0184414 PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE
The present disclosure provides a method for treating stroke by administering to a subject an anticoagulant, e.g., recombinant tissue plasminogen activator...
2016/0184413 FORMULATION FOR STABILIZING PROTEINS, WHICH IS FREE OF MAMMALIAN EXCIPIENT
The present invention pertains to a formulation comprising a hydrophilic polymer, a mixture of a polyalcohol and a sugar, wherein the weight ratio of...
2016/0184412 Glycopegylated Factor IX
Conjugates between Factor IX and PEG moieties, are disclosed in the present application. The conjugates are linked via a glycosyl linking group interposed...
2016/0184411 DRUG TARGET FOR PREVENTING AND TREATING PERIODONTAL DISEASE, IMPROVING HEALING OF PERIODONTAL WOUNDS AND...
The present invention relates to the use of a component of the plasminogen-activating pathway and use of compounds which have the capacity to activate...
2016/0184410 TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II
Methods of treating glycogen storage disease type II, by administering acid .alpha.-glucosidase, are described, as are compositions for use in treatment of...
2016/0184409 TREATMENT OF ALPHA-GALACTOSIDASE A DEFICIENCY
The invention provides methods of treating .alpha.-galactosidase A deficiency. Dosage forms, methods of administration, and methods of analyzing human...
2016/0184408 Variant, Recombinant Beta-Glucocerebrosidase Proteins With Increased Stability And Increased Retained Catalytic...
Described herein are variant, recombinant (.beta.-glucocerebrosidase proteins characterized as having increased stability relative to recombinant wild-type...
2016/0184407 Novel Class of Therapeutic Protein Based Molecules
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides...
2016/0184406 COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide, which has the...
2016/0184405 FLT4 (VEGFR-3) AS A TARGET FOR TUMOR IMAGING AND ANTI-TUMOR THERAPY
The present invention provide purified Flt4 receptor tyrosine kinase polypeptides and fragments thereof, polynucleotides encoding such polypeptides, antibodies...
2016/0184404 NOVEL HEMOGLOBIN-DERIVED PEPTIDE BASED PHARMACEUTICAL COMPOSITIONS
The present invention relates to a pharmaceutical composition comprising at least one Toll-like receptor (TLR)-activating amphiphilic lipid and at least one...
2016/0184403 TREATMENT OF COAGULATION DISEASE BY ADMINISTRATION OF RECOMBINANT VWF
The present invention provides methods of treating coagulation disease, including hemophilia and von Willebrand disease by administering recombinant von...
2016/0184402 USE OF PROINSULIN FOR IMMUNE SYSTEM MODULATION
The present disclosure relates to a composition for promoting immune activity including a protein selected from the group consisting of dimeric proinsulin,...
2016/0184401 NON-AGGLOMERATING BIOCONJUGATES OF AMYLIN AND AMYLIN-MIMETIC COMPOUNDS, COMPOSITIONS COMPRISING THE SAME, AND...
The present disclosure concerns new non-agglomerating bioconjugates of amylin, amylin-mimetic compounds, and combinations comprising the same. Methodology of...
2016/0184400 PEPTIDE CONJUGATES OF GLP-1 RECEPTOR AGONISTS AND GASTRIN AND THEIR USE
The present invention relates, inter alia, to certain peptide conjugates, and to the use of the conjugates in the treatment of a variety of diseases or...
2016/0184399 COMBINED PHARMACEUTICAL COMPOSITION
The present disclosure relates to a combined pharmaceutical composition, adapted for simultaneous, separate, or sequential administration for treating cancer...
2016/0184398 TARGETED CARGO PROTEIN COMBINATION THERAPY
The present invention combines a targeted cargo protein with an active agent for the treatment of a disease or condition.
2016/0184397 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF DISEASE INVOLVING ABNORMAL ACCUMULATION OF...
Disclosed is a pharmaceutical composition for the treatment and/or prevention of a disease involving abnormal accumulation of amyloid .beta. protein comprising...
2016/0184396 HUMAN-ORIGINATED EGF DOMAIN PROTEINS AND USE OF THE SAME
In the invention, the minimum inhibitory concentrations of human-originated EGF domain proteins against different Gram-negative bacteria are detected with the...
2016/0184395 METHOD TO FUNCTIONALIZE CELLS IN HUMAN BLOOD, OTHER FLUIDS AND TISSUES USING NANOPARTICLES
Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion...
2016/0184394 ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSID AND METHODS OF USE THEREOF
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal...
2016/0184393 Treatment of X-linked hypohidrotic ectodermal dysplasia with a fusion EDA1 protein
The invention relates to methods for the temporal administration of EDA agonists, in particular EDI200, which correlate to optimal therapeutic response windows...
2016/0184392 Treatment Of Chronic Nephropathies Using Soluble Complement Receptor Type I (sCR1)
A method is disclosed for treating nephropathies involving undesired alternative pathway complement activation by administration of a complement inhibitory...
2016/0184391 TREATMENT OF GRAFT REJECTION BY ADMINISTERING A COMPLEMENT INHIBITOR TO AN ORGAN PRIOR TO TRANSPLANT
Methods of prolonging survival of a transplanted organ, as well as methods of preventing or attenuating rejection of a transplanted organ are provided. These...
2016/0184390 Systems and Methods for Improved Delivery of Osteoinductive Molecules in Bone Repair
Systems and methods for preparing synthetic osteoinductive bone grafts are provided in which a porous ceramic granule, which may be incorporated within a...
2016/0184389 USE OF IMMUNOMODULATORY PROTEIN FROM GANODERMA IN INHIBITING CANCER STEM CELLS
The present invention relates to a new use of an immunomodulatory protein derived from Ganoderma or a recombinant or a composition thereof in inhibiting cancel...
2016/0184388 Use of Somatostatin Analogs in Control of Hypoglycemia
The present invention relates to the use of a Somatostatin (SRIF) analog which has a high binding affinity to human SSTR1,2,3,5, or a pharmaceutically...
2016/0184387 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
Provided are non-NHE3-binding agents having activity as phosphate transport/uptake inhibitors in the gastrointestinal tract, including in the small intestine,...
2016/0184386 AQUEOUS SUSTAINED RELEASE COMPOSITIONS OF LHRH ANALOGUES
An aqueous pharmaceutical composition for the sustained release of an LHRH analogue, in particular for a sustained release compatible with therapeutic...
2016/0184385 NOVEL PEPTIDE HAVING ABILITY TO SYNTHESIZE COLLAGEN AND USE THEREOF
Provided are a cosmetic composition and pharmaceutical composition for wound healing capable of efficiently performing collagen synthesis in skin, wherein the...
2016/0184384 Tetrapeptides Derived from Human C-X-C Chemokines Useful for Treatment of Various Skin Conditions
Tetrapeptides consisting of (I or V)-X1-K-X2, where X1 can be selected from E, Q or K, and X2 can be selected from M, F, I, W, or V, exhibit diverse...
2016/0184383 METHOD OF TREATING CANCER
The present invention provides a method of treating cancer in a subject wherein the method comprising administering to the subject an IAP antagonist and a p38...
2016/0184382 COMPOSITION INCLUDING ORIENTAL MEDICINE TO TREAT NEOPLASTIC DISEASE
Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang....
2016/0184381 Herbal Combinations for Treatment of a Skin Condition
A method and medicine for treating melanoma, BCC (basal cell carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, comprising...
2016/0184380 Molecular Combinations for Cancer or Other Disease Treatment
A method and medicine for treating leukemia or other cancer or disease condition including administering periodic doses of a combination of one or more of...
2016/0184379 Molecular Combinations for Cancer or Other Disease Treatment
A method and medicine for treating leukemia or other cancer or disease condition including administering periodic doses of a combination of one or more of...
2016/0184378 FAT ACCUMULATION INHIBITOR, DRUG, PROPHYLACTIC OR THERAPEUTIC AGENT FOR FATTY LIVER, FOOD OR DRINK, AND METHOD...
A fat accumulation inhibitor includes, as an active ingredient, a plant belonging to the genus Cirsium.
2016/0184377 Method for Promoting Respiratory Burst Activity Promoter and Immunostimulating in Type 2 Diabetic Patients
To confirm the safety of a fermented papaya preparation in type 2 diabetic patients while determining its in vivo effect on respiratory burst in human...
2016/0184376 Method for Promoting ATP Production and Mitochondrial Activity, and Immunostimulating in Type 2 Diabetic Patients
An object of the present invention is to confirm the safety of a fermented papaya preparation in type 2 diabetic patients while determining its effect on ATP...
2016/0184375 Sea Buckthorn Compositions and Associated Methods
Compositions having an effective amount of a Sea Buckthorn extract and an inert carrier and methods of use therefor are disclosed and described. Such methods...
2016/0184374 SANDALWOOD OIL AND ITS USES
Provided herein are compositions of sandalwood oil and methods of making and using such compositions.
2016/0184373 PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF
The pharmaceutical composition is a formulation prepared by the raw materials in parts by weight: 1-300 parts of chlorogenic acid and 1-50 parts of Ganoderma...
2016/0184372 COMPOSITION COMPRISING LACTIC ACID BACTERIA FOR USE IN THE PREVENTIVE AND/OR CURATIVE TREATMENT OF BACTERIAL...
A composition comprising lactic bacteria for topical vaginal use is described. The composition is effectively applicable in the preventive and/or curative...
2016/0184371 PROBIOTIC FOR INFANTILE EXCESSIVE CRYING
Provided is a bacterial composition which comprises from 10.sup.4 to 10.sup.12 cfu/g of Pediococcus pentosaceus cells which have the ability to induce the...
2016/0184370 Compositions and Methods
Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of...
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