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Patent # Description
2016/0193317 PROTECTIVE ANTIGEN COMPLEXES WITH INCREASED STABILITY AND USES THEREOF
Immunogenic compositions against Bacillus anthracis comprising a stabilized protective antigen complex are disclosed. The stabilized complex comprises...
2016/0193316 Inducing Cellular Immune Responses to Plasmodium Falciparum Using Peptide and Nucleic Acid Compositions
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare Plasmodium falciparum epitopes, and to...
2016/0193315 PEPTIDES SHARED AMONG LETHAL CANCERS AND THERAPEUTIC COMPOSITIONS COMPRISING SAID PEPTIDES
The present invention provides cancer peptides related to rapid replication and shared among different histological cancer types. The peptides are provided in...
2016/0193314 PARTIAL PEPTIDE OF SURVIVIN PRESENTED ON MHC CLASS II MOLECULE AND USE THEREOF
The object aims to provide: a novel tumor antigen; a novel therapeutic agent useful in a method for treating a malignant neoplasm by utilizing the tumor...
2016/0193313 IMMUNOGENIC COMPOSITIONS AND METHODS FOR TREATING NEOPLASIA
The invention provides immunogenic compositions comprising neoplastic cells expressing a cytokine (GM-CSF) formulated with at least one TLR agonist and methods...
2016/0193312 ANTIFUGETACTIC AGENTS FOR THE TREATMENT OF LIVER CANCERS
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides...
2016/0193311 ANTIFUGETACTIC AGENTS FOR THE TREATMENT OF SKIN CANCERS
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides...
2016/0193310 RM2 ANTIGENS AND USE THEREOF
Described herein are synthetic glycan conjugates, immmunogenic compositions thereof, vaccines thereof, and kits thereof. The present invention further provides...
2016/0193309 METHOD TO GENERATE ANTIBODIES TO ION CHANNELS
The present invention provides a method for generating a functionally modifying antibody to an ion channel comprising immunizing a host with a cyclic peptide...
2016/0193308 DPP-4-TARGETING VACCINE FOR TREATING DIABETES
The present invention provides a vaccine for the prophylaxis or treatment of diabetes using a polypeptide containing the amino acid sequence shown by SEQ ID...
2016/0193307 METHOD AND COMPOSITIONS FOR INHIBITING OR PREVENTING ADVERSE EFFECTS OF ORAL ANTIBIOTICS
This invention provides, in part, various compositions and methods for protecting the gastrointestinal microbiome from antibiotic disruption.
2016/0193306 MULTI-SUPPLEMENT COMPOSITIONS
This document provides dietary supplement compositions. For example, multi-supplement compositions having combinations of dietary supplement formulations...
2016/0193305 DRUG DELIVERY METHOD
The present invention relates to a new drug delivery strategy based on prodrug conversion, in which a water-soluble prodrug and its converting enzyme are...
2016/0193304 PROCESS FOR CONCENTRATION OF A POLYPEPTIDE
The present invention comprises a method of concentrating a composition comprising a polypeptide of interest and the use of such concentrated composition for...
2016/0193303 LEVERAGING OXIDATIVE STRESS PATHWAYS IN LACTIC ACID BACTERIA TO PROMOTE GUT HOMEOSTASIS
Disclosed herein are compositions and methods for providing an antioxidant effect to a subject, e.g., modulating or otherwise improving oxidative stress...
2016/0193302 LACTOFERRIN AND MEMORY AND LEARNING SPEED IN CHILDREN
The present invention generally relates to the development of cognitive function in infants. More particularly, the present invention provides the use of...
2016/0193301 Eye Drop Formulation
A single unit dosage eye drop formulation including 0.1% to 0.6% by weight Thymosin .beta.4 (T.beta.4) and an ophthalmically acceptable carrier.
2016/0193300 Methods of Using Interleukin-10 for Treating Diseases and Disorders
Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to IL-10,...
2016/0193299 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS
The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein...
2016/0193298 THERAPEUTIC USE OF VEGF-C AND CCBE1
The present invention relates to therapeutic methods, uses and compositions comprising CCBE1 and VEGF-C for treating disorders and conditions involving...
2016/0193297 FUSION PROTEINS FOR TREATING METABOLIC DISORDERS
The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved...
2016/0193296 METHODS FOR TREATMENT OF MICROCEPHALY ASSOCIATED AUTISM DISORDERS
The invention features methods for the treatment of one or more symptoms of microcephaly associated autism disorders e.g., Christianson syndrome, by...
2016/0193295 STABILIZATION OF FC-CONTAINING POLYPEPTIDES
This disclosure provides polypeptides comprising an antibody Fc region having a deletion of one or more cysteine residues in the hinge region and substitution...
2016/0193294 COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR
This invention discloses the use of an E-selectin antagonist and a mobilizer of hematopoietic stem cells or progenitor cells in methods and compositions for...
2016/0193293 OINTMENT CONTAINING A HYDROLYZED FIBROIN AND MANUFACTURING METHOD OF SAME
Embodiments of the present invention provide a topical agent that is a preparation containing hydrolyzed silk. The topical agent is applied to a wound site for...
2016/0193292 Cell Permeable Inhibitors Of The Scaffold Protein Plenty Of SH3 Domains (POSH) Or Sh3Rfl
Plenty of SII3 (POSH) and INK-interacting protein 1 (JIP-1) function as a multi-protein scaffold network for TCR-mediated JNK1 activation in CD8+ T-cells....
2016/0193291 METHOD OF REGULATING NEURONAL AXON ELONGATION
The present invention includes a treating step of treating neuronal growth cone with a regulatory factor to regulate macropinocytosis caused by a repulsive...
2016/0193290 Methods of Reducing Myocardial Injury Following Myocardial Infarction
The present invention discloses methods of reducing injury resulting from cardiovascular disease, such as myocardial infarction, and/or promoting myocardial...
2016/0193289 MOLECULAR SIGNATURE OF CANCER
The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
2016/0193288 THERAPEUTIC TREM-1 PEPTIDES
A polypeptide comprising one or more sequences derived from CDR2 or CDR3 of a TREM-1 protein, characterised by the ability to treat, ameliorate, or lessen the...
2016/0193287 USES OF BT LIPOPEPTIDES AS THERAPEUTICS FOR OBESITY AND RELATED DISEASES
The invention provides compositions and uses for treating or preventing obesity and related diseases in patients.
2016/0193286 Treatment of Rhinosinusitis with P-glycoprotein Inhibitors
Provided herein are, inter alia, methods for treating rhinosinusitis with P-glycoprotein inhibitors. A subject having rhinosinusitis is identified and then...
2016/0193285 ORAL OCTREOTIDE ADMINISTERED IN COMBINATION WITH OTHER THERAPEUTIC AGENTS
This invention relates to combination therapy of a subject suffering from acromegaly. The method of treatment comprises administration to the subject of a...
2016/0193284 USE OF A BACTERIUM ISOLATED FROM THE GENUS PSEUDOALTEROMONAS, CYCLOLIPOPEPTIDES AND USES THEREOF
The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative,...
2016/0193283 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
Methods for treating solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for...
2016/0193282 MAGNESIUM-CONTAINING OXYTOCIN FORMULATIONS AND METHODS OF USE
Disclosed are magnesium-containing oxytocin peptide formulations or compositions comprising an oxytocin peptide and a magnesium salt that produces synergistic...
2016/0193281 MAP KINASE P38 BINDING COMPOUNDS
A compound comprising the amino acid sequence HKSRALLIFQKIMWLRRQ (SEQ ID No: 1) or comprising a part of said amino acid sequence of 7 or more amino acids, or...
2016/0193280 COMPOSITIONS AND METHODS FOR TREATING PRECOCIOUS PUBERTY
The present invention is directed to the controlled delivery of gonadotropin-releasing hormone (GnRH) agonists, preferably from a polymeric material that is...
2016/0193279 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AXONAL AND NEURONAL DEGENERATION
The present invention generally relates to methods and compositions for preventing or treating axonal and/or neuronal degeneration in a subject by...
2016/0193278 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY
The disclosure generally describes methods of preventing or treating Lebers hereditary optic neuropathy (LHON). The methods comprise administering an effective...
2016/0193277 IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES
The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions...
2016/0193276 TRANSMUCOSAL DELIVERY OF GLATIRAMER ACETATE
The present invention provides an oral tablet comprising glatiramer acetate in an amount from about 10 percent to about 60 percent by weight and one or more...
2016/0193275 Sugar Cane Derived Extracts and Methods of Treatment
The invention relates to extracts produced from sugar cane processing stream products having desirable properties and health benefits. More particularly the...
2016/0193274 PROCESS FOR THE LARGE SCALE PRODUCTION OF FRUIT CELLS AND TREATMENT OF DISEASES WITH SUCH CELLS
The disclosure provides a method for treating, reducing, alleviating or preventing metabolic syndrome or metabolic malady, comprising administering a...
2016/0193273 DIETARY SUPPLEMENT COMPOSITIONS
This document provides dietary supplement compositions. For example, dietary supplement compositions having an acetylcholinesterase inhibitor (e.g., huperzine...
2016/0193272 Use of Extracts or Materials Extracted From Piper Cubeba L. as an Effective Component in a Drug for the...
Disclosed is a method for the preparation of a dry extract from the fruit of Piper cubeba L. In the disclosed method, in a first step, the fruit of Piper...
2016/0193271 Procedure and extraction of a regenerative product for vital organs and a by-product for cutaneous use
A procedure and extraction of a regenerative product and a by-product for cutaneous use consisting of an infusion based on one litre of water boiled at between...
2016/0193270 ANTISEPTIC COMPOSITONS AND METHODS OF USE
Antimicrobial compositions, especially those useful when applied topically to tissue, such as mucosal tissues (i.e., mucous membranes), that include an...
2016/0193269 ANTI-DIABETIC COMPOSITION
The present invention provides anti-diabetic composition comprising Inula racemosa extract and sitagliptin and a process for preparing the composition. The...
2016/0193268 ANDROGRAPHIS PANICULATA EXTRACT
An extract of Andrographis particulata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, ...
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