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Patent # Description
2016/0193217 THERAPEUTIC AGENT FOR OPHTHALMIC DISEASE
The present invention provides a therapeutic agent or prophylactic agent for an ophthalmic disease caused by ocular angiogenesis, which contains a morpholine...
2016/0193216 IRAK INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
2016/0193215 NOVEL COMPOUNDS AS HIF-1 ALPHA INHIBITORS AND MANUFACTURING PROCESS THEREOF
The present invention relates to novel compounds as HIF-1.alpha. inhibitors, manufacturing process thereof, and a pharmaceutical compositions. The compounds...
2016/0193214 SMALL MOLECULES TO ENHANCE P53 ACTIVITY
A method of enhancing p53 activity of a p53 mutant polypeptide is provided. The method includes interacting a compound to an open L1/S3 binding site of the p53...
2016/0193213 PHARMACEUTICAL FORMULATIONS OF XANTHINE OR XANTHINE DERIVATIVES
Pharmaceutical compositions and methods for treating various diseases and pathologies, such as Dupuytren contracture, are described, the compositions...
2016/0193212 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR
The present invention relates to new cyclopropyl modulators of P2Y12 receptor activity, pharmaceutical compositions thereof, and methods of use thereof. ...
2016/0193211 COMBINATIONS OF A BTK INHIBITOR AND FLUOROURACIL FOR TREATING CANCERS
The present application describes therapies for the effective treatment of colon and colorectal carcinomas. The present invention relates to a pharmaceutical...
2016/0193210 ANTITUMOR DRUG FOR INTERMITTENT ADMINISTRATION OF FGFR INHIBITOR
The problem to be solved by the present invention is to provide a potent and highly selective novel FGFR inhibitor, and an antitumor agent having reduced side...
2016/0193209 NAMPT INHIBITORS
Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is...
2016/0193208 Identification of Non-Small Cell Lung Carcinoma (NSCLC) Tumors Expressing PDGFR-alpha
The invention discloses a previously unidentified subset of mammalian non-small cell lung carcinomas (NSCLC) in which platelet-derived growth factor receptor...
2016/0193207 PLASMODIAL SURFACE ANION CHANNEL INHIBITORS FOR THE TREATMENT OR PREVENTION OF MALARIA
The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: ...
2016/0193206 BET-PROTEIN-INHIBITING DIHYDROPYRIDOPYRAZINONES
The present invention relates to BET protein-inhibitory, especially BRD4-inhibitory, dihydropyridopyrazinones of the general formula (I) ##STR00001## in which A,...
2016/0193205 METHOD OF TREATMENT FOR MENTAL DISORDERS
The invention relates to a medicament or a method for treating mental disorders, in detail, ADHD comprising lurasidone, or a combination of lurasidone and a...
2016/0193204 Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs,...
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, ...
2016/0193203 TREATMENT OF PERITONEAL INJURY USING JAK INHIBITORS
The invention provides, in certain embodiments, a method of preventing and/or treating peritoneal injury and/or diminished function by administering an...
2016/0193202 THERAPEUTIC TREATMENT FOR DRUG POISONING AND ADDICTION
The present invention relates to methods of treating or preventing drug poisoning and drug addiction in a subject. These methods involve administering to a...
2016/0193201 NEUROPROTECTIVE CB2 RECEPTOR AGONISTS
A method of treating or preventing a neuroinflammatory and/or neurodegenerative disease in a subject by administering a pharmaceutically effective amount of a...
2016/0193200 BENZAMIDE DERIVATIVES AND THEIR USE AS HSP90 INHIBTORS
The invention provides a compound which is (a) a phenylamide derivative of formula (I) or a tautomer thereof, or (b) a pharmaceutically acceptable salt,...
2016/0193199 METHODS OF TREATING FRAGILE X SYNDROME AND RELATED DISORDERS
The present invention provides methods of alleviating a sign or a symptom of Fragile X Syndrome and relates disorders such as autism spectrum disorders.
2016/0193198 INTRAVENTRICULAR DRUG DELIVERY SYSTEM FOR IMPROVING OUTCOME AFTER A BRAIN INJURY AFFECTING CEREBRAL BLOOD FLOW
The described invention provides a flowable sustained release microparticulate composition effective to improve cerebral perfusion and to treat a delayed...
2016/0193197 USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY...
The use of at least one compound of formula I or II or pharmaceutically acceptable salts thereof, for preparing a pharmaceutical composition that acts by...
2016/0193196 IMMEDIATE-RELEASE TABLET FORMULATIONS OF A THROMBIN RECEPTOR ANTAGONIST
Immediate-release formulations for oral administration of a thrombin receptor antagonist are provided. Certain formulations of higher API loading demonstrate...
2016/0193195 PHARMACEUTICAL USE OF HEXAHYDRO-DIBENZO[A,G]QUINOLIZINE COMPOUNDS
Use of hexahydro-dibenzo[a,g]quinolizine compounds as shown in formula(I) in preparing a medicine for treating and/or preventing benign prostate hyperplasia...
2016/0193194 Compositions and Methods for the Treatment of Presbyopia
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine and a cycloplegic agent. The...
2016/0193193 Compositions and Methods for the Treatment of Presbyopia
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine and a polyol. The compositions...
2016/0193192 EXTRACELLULAR ALLOSTERIC INHIBITOR BINDING DOMAIN FROM A TYROSINE KINASE RECEPTOR
The present invention relates to an extracellular binding domain for an allosteric inhibitor, whereby said binding domain is derived from a single membrane...
2016/0193191 ANTAGONISTS OF CHEMOKINE RECEPTORS
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl...
2016/0193190 Targeting Metabolic Adaptive Responses to Chemotherapy
Methods for targeting adaptive responses to chemotherapy are described. In various embodiments, a method comprises administering at least one compound that...
2016/0193189 CRYSTALLINE FORMS OF 3-[5-(2-FLUOROPHENYL)-[1,2,4]OXADIAZOL-3-YL]-BENZOIC ACID FOR THE TREATMENT OF DISEASE
The present invention relates to crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, pharmaceutical compositions and dosage forms...
2016/0193188 METHODS AND COMPOSITIONS FOR INCREASING THE EFFECTIVENESS OF ANTIVIRAL AGENTS
Compositions and methods of the present invention comprise novel formulations for increasing the effectiveness of antiviral agents and for preventing and...
2016/0193187 COMPOSITIONS AND METHODS FOR TREATING PLASMA CELL DISORDERS AND B-CELL PROLYMPHOCYTIC DISORDERS
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of plasma cells and/or B-cells, with a therapeutically...
2016/0193186 COMPOSITIONS AND METHODS FOR TREATING CHRONIC URTICARIA
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of mast cells, basophils, eosinophils, or a combination...
2016/0193185 DIAZOLE AMIDES
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam...
2016/0193184 METHOD FOR INDUCTION OF A HEAT SHOCK PROTEIN, ANTI-STRESS OR REGULATION OF AN AUTONOMIC NERVE
A method for induction of a heat shock protein, anti-stress or regulation of an autonomic nerve comprises: administering a mammalian subject in need thereof a...
2016/0193183 Pharmaceutical composition comprising ...
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from ...
2016/0193182 COATING COMPOSITION
The invention refers to a coating composition which, calculated on dry weight, is comprising at least 20% by weight polyvinyl alcohol and 0.1 to 20% by weight,...
2016/0193181 AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related...
2016/0193180 COMPOSITION FOR PREVENTING AND TREATING IMMUNE DISEASES CONTAINING DAURINOL COMPOUND AS ACTIVE INGREDIENT
The daurinol compound according to the present invention exhibits excellent therapeutic effects on arthritis and inflammatory bowel diseases by having an...
2016/0193179 Treatment of Cardiovascular Risk in Diabetic Patients
Disclosed herein are methods of treating cardiovascular risk in diabetic patients using a pharmaceutically acceptable form of ...
2016/0193178 BERAPROST-CONTAINING PATCH
The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of...
2016/0193177 COMPOSITIONS, METHODS AND SYSTEMS FOR THE TREATMENT OF CUTANEOUS DISORDERS
Provided herein are devices, systems, kits and methods for treating skin conditions, ailments or diseases, such as skin warts. In some examples, a device for...
2016/0193176 CHLOROGENIC ACID POWDER-INJECTION AND PREPARATION METHOD THEREOF
The present invention provides a chlorogenic acid powder-injection. The chlorogenic acid powder-injection is prepared from the following raw materials in parts...
2016/0193175 Use of Docosahexaenoic Glycerides For The Treatment Of Tumorous Diseases
The present invention relates to the use of an oil enriched in docosahexaenoic acid, which is conjugated to triglyceride, for manufacturing a pharmaceutical...
2016/0193174 COMPOSITION CONTAINING MONOACETYLDIGLYCERIDE COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING ATOPIC...
The present invention relates to a pharmaceutical composition, functional health food composition, quasi-drug composition, and cosmetic composition containing...
2016/0193173 KETONE BODIES AND KETONE BODY ESTERS AS BLOOD LIPID LOWERING AGENTS
The subject disclosure provides compositions for reducing serum cholesterol and/or triglyceride levels in subjects. These compositions can comprise racemic...
2016/0193172 Method For Treating Metabolic Syndrome
Methods for detecting risks for and/or causes of metabolic syndrome or hyperferritinemia in accordance with several embodiments can include the step of...
2016/0193171 Heptadecanoic Acid Supplement to Human Diet
Methods for detecting risks for and/or causes of metabolic syndrome or hyperferritinemia in accordance with several embodiments can include the step of...
2016/0193170 Use of Heptadecanoic Acid (C17:0) To Detect Risk Of And Treat Hyperferritinemia and Metabolic Syndrome
Methods for detecting risks for and/or causes of metabolic syndrome or hyperferritinemia in accordance with several embodiments can include the step of...
2016/0193169 Compositions And Methods For Treating Intestinal Hyperpermeability
The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including conditions...
2016/0193168 Treatment of Pulmonary Arterial Hypertension with Leukotriene Inhibitors
Pulmonary arterial hypertension (PAH) can be prevented in persons susceptible to the diseases and PAH patients can be treated by administering an effective...
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