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Patent # Description
2016/0194667 Method for Producing Myo-Inositol and Myo-Inositol Derivative
To impart significantly improved myo-inositol producing capability, suitable for use in recombinant DNA techniques and synthetic biology methods, to a host...
2016/0194666 Process for Production of Biogas
The invention relates to a process for production of biogas from a biodegradable substrate under anaerobic conditions, comprising the steps of introducing the...
2016/0194665 METHODS AND COMPOSITIONS FOR INACTIVATING ALPHA 1,6 FUCOSYLTRANSFERASE (FUT8) GENE EXPRESSION
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or...
2016/0194664 COMPOSITIONS AND METHODS FOR GENERATING ADENO-ASSOCIATED VIRAL VECTORS WITH UNDETECTABLE CAPSID GENE CONTAMINATION
In one aspect, the present invention provides an intron-modified capsid expression cassette useful for generating adeno-associated virus (AAV) vector...
2016/0194663 REPLICATION-DEFECTIVE ARENAVIRUS VECTORS
The invention relates to an infectious arenavirus particle that is engineered to contain a genome with the ability to amplify and express its genetic...
2016/0194662 RECOMBINANT VIRUS-LIKE PARTICLES ENCODED BY MULTI-GENE VECTOR
The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques...
2016/0194661 EXOGENOUS GENE EXPRESSION VECTOR, TRANSFORMANT DISCRIMINATION MARKER, AND TRANSFORMANT
This invention is intended to develop a promoter that can strongly induce marker gene expression throughout an embryo, so as to simply, efficiently, and...
2016/0194660 EXPRESSION VECTORS FOR RECOMBINANT PROTEIN PRODUCTION IN MAMMALIAN CELLS
The invention provides expression vectors that support high levels of polypeptide expression in mammalian cells. The vectors contain at least one expression...
2016/0194659 Self-Reproducing Hybrid Plants
Compositions and methods for the production of self-reproducing hybrid plants are provided. Compositions include suppression cassettes encoding polynucleotides...
2016/0194658 NUCAMPHOLIN NUCLEIC ACID MOLECULES TO CONTROL COLEOPTERAN INSECT PESTS
This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference-mediated inhibition of target...
2016/0194657 GLYCINE MAX RESISTANCE GENE(S) AND USE THEREOF TO ENGINEER PLANTS WITH BROAD-SPECTRUM RESISTANCE TO FUNGAL...
The present invention relates to a method of increasing plant resistance to plant pathogens, particularly Sudden Death Syndrome in soybean against Fusarium...
2016/0194656 PLANTS COMPRISING EVENTS PP009-401, PP009-415, AND PP009-469, COMPOSITIONS, SEQUENCES, AND METHODS FOR...
The invention provides glyphosate tolerant transgenic turfgrass plants, plant material, and seeds that have a specific transformation event. Also provided are...
2016/0194655 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES
The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at...
2016/0194654 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES
The present invention refers to a plant or plant part comprising (i) a recombinant polynucleotide encoding a wildtype or mut-PPO polypeptide, and (ii) a...
2016/0194653 HYPERSENSITIVE ABA RECEPTORS
Hypersensitive PYR/PYL polypeptides, compositions, and methods are provided.
2016/0194652 EXPRESSION OF THERMOSTABLE STARCH SYNTHASE GENES IMPROVES THE YIELD IN HEAT STRESS
Genetically-modified plants having increased tolerance to heat stress are described. Methods of producing such genetically-modified plants are also disclosed....
2016/0194651 METHODS OF MODULATING SEED AND ORGAN SIZE IN PLANTS
This invention relates to a plant E3 ubiquitin ligase (termed DA2) which acts synergistically with DA1 to control seed and organ size. Methods of increasing...
2016/0194650 Transcriptional Regulation for Improved Plant Productivity
Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and...
2016/0194649 LIPID AND GROWTH TRAIT GENES
The present disclosure provides novel lipid and growth genes that when over expressed in an organism results in a change in the lipid profile, and/or lipid...
2016/0194648 CONTROL OF COLD-INDUCED SWEETENING AND REDUCTION OF ACRYLAMIDE LEVELS IN POTATO OR SWEET POTATO
The present invention is directed to methods and compositions to eliminate cold storage-induced sweetening of potato or sweet potato. The invention is...
2016/0194647 Expression Vector
An expression vector including two separately inducible converging promoters P1 and P2, and expression system including such an expression vector and an...
2016/0194646 Methods and Compositions for Selecting siRNA of Improved Functionality
Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize...
2016/0194645 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF MUTANT EGFR GENE
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a mutant Epidermal Growth Factor Receptor (EGFR), and methods of using the dsRNA...
2016/0194644 LIGASE E3 RNF185 INHIBITORS AND USES THEREOF
The present relates to the use of an E3 ligase RNF185 inhibitor for treating cystic fibrosis and chronic obstructive pulmonary disease.
2016/0194643 Methods of Identifying and Treating Poor Prognosis Cancers
The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis...
2016/0194642 SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOREGULATORY AGENTS
Aspects of the invention relate to nanoscale constructs and related methods and compositions thereof. The compositions of the invention are useful for treating...
2016/0194641 G-RICH isoDNA SEQUENCES FORMING G-QUADRUPLEX STRUCTURE, THEIR FUNCTION AS APTAMERS AND A PROCESS FOR THE...
The present invention relates to G-quadruplex forming isoDNA aptamers and a process for the preparation thereof. The present invention further relates to a...
2016/0194640 DESIGN AND CONSTRUCTION OF BIFUNCTIONAL SHORT HAIRPIN RNA
A method for designing a bi-shRNA expression cassette encoding a bi-shRNA comprising: selecting one or more target site sequences; providing a backbone...
2016/0194639 INHIBITING CANCER METASTASIS
The present invention relates to methods and compositions for determining whether a cancer patient is at increased risk for developing metastatic spread of the...
2016/0194638 COMPOUNDS AND METHODS FOR MODULATING TARGET NUCLEAR AND SUB-NUCLEAR NUCLEIC ACID MOLECULES IN CELLS AND ANIMALS
The present invention provides compounds and methods for modulating target nucleic acids found in organelles or sub-organelles of cells. The invention...
2016/0194637 COMPOUNDS AND METHODS FOR MODULATING TARGET NUCLEAR AND SUB-NUCLEAR NUCLEIC ACID MOLECULES IN CELLS AND ANIMALS
The present invention provides compounds and methods for modulating target nucleic acids found in organelles or sub-organelles of cells. The invention...
2016/0194636 MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE
The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53...
2016/0194635 METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL
The present invention provides a method of quantifying miR-185 as a potential biomarker in lipid disorder or cardiovascular diseases in human. The present...
2016/0194634 Methods for treating and/or limiting development of diabetes
The present invention provides methods for identifying candidate compounds for limiting development of and/or treating diabetes, and methods for limiting...
2016/0194633 Lipid Formulated Compositions and Methods for Inhibiting Expression of Serum Amyloid A Gene
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a Serum Amyloid A (SAA) gene, and methods of using the dsRNA to inhibit...
2016/0194632 TARGETING NON-CODING RNA FOR RNA INTERFERENCE
A broad and extensive new category of targets for ribonucleic acids (RNAs) with interference activity (iRNAs), exclusive of the traditional messenger RNA...
2016/0194631 Methods for Modulation of Autophagy Through the Modulation of Autophagy-Inhibiting Gene Products
The present disclosure relates to methods for the modulation of autophagy and the treatment of autophgy-related diseases, including cancer, neurodegenerative...
2016/0194630 REDUCING NONSENSE-MEDIATED MRNA DECAY
The present disclosure relates to compositions and methods for inhibiting nonsense-mediated mRNA decay in a gene-specific manner, for example in the treatment...
2016/0194629 SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow...
2016/0194628 METHODS FOR PRODUCING STRANDED cDNA LIBRARIES
The present system provides novel methods and compositions for selecting a particular strand of RNA and/or producing a cDNA library that results in an unbiased...
2016/0194627 COMBINATORIAL ANTIBODY LIBRARIES AND USES THEREOF
Methods for making a combinatorial antibody library from human germline segments are provided. Also provided are libraries of nucleic acid molecules compiled...
2016/0194626 Universal Fibronectin Type III Bottom-Side Binding Domain Libraries
The invention pertains to a natural-variant combinatorial library of fibronectin Type 3 domain (Fn3) polypeptides useful in screening for the presence of one...
2016/0194625 CHIMERIC POLYNUCLEOTIDES
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of chimeric polynucleotide molecules.
2016/0194624 SYSTEM FOR OPTICAL STIMULATION OF TARGET CELLS
Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing a...
2016/0194623 NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF
The present invention relates to mutated tissue plasminogen activators, and their use for treating thrombotic diseases.
2016/0194622 FUSION PROTEIN HAVINGH FACTOR VII ACTIVITY
A fusion protein comprising factor VII (FVII) and transferrin according to the present invention has an improved specific activity of FVII compared to existing...
2016/0194621 Compositions and Methods for Treating Celiac Sprue Disease
The invention provides compositions and methods for treating celiac sprue.
2016/0194620 METHOD FOR DESIGNING MUTATED ENZYME, METHOD FOR PREPARING THE SAME, AND MUTATED ENZYME
A novel method for improving an enzyme hydrolyzing an .alpha.-1,6-glycosidic linkage is provided. A mutated enzyme is made by obtaining the amino acid sequence...
2016/0194619 METHODS OF COMBINED BIOPROCESSING AND RELATED MICROORGANISMS, THERMOPHILIC AND/OR ACIDOPHILIC ENZYMES, AND...
A genetically modified organism comprising: at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus...
2016/0194618 PHYTASE
Polypeptides having phytase activity and polynucleotide sequences encoding the phytases are provided. The gene expresses the phytase at a level of at least 7...
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