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MODULATION OF AXON DEGENERATION
The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using...
METHOD AND COMPOSITION TO PREVENT OR IMPROVE SYMPTOMS OF MUSCULOSKELETAL
The present invention relates generally to compositions and methods of using compositions comprised of undenatured cartilage in the form of an isolated native...
Factor VIII-Fc Chimeric and Hybrid Polypeptides, and Methods of Use
The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric...
FACTOR VIII-XTEN FUSIONS AND USES THEREOF
The present invention provides chimeric proteins comprising a Factor VIII (FVIII) polypeptide and XTEN polypeptides. The FVIII polypeptide can have a reduced...
The present disclosure is directed to transdermal and moisturizing compositions.
Insulin glargine/lixisenatide fixed ratio formulation
The present invention refers to a pharmaceutical composition comprising (a) lixisenatide or/and a pharmaceutically acceptable salt thereof, and (b) insulin...
COMPOSITION FOR TREATING HYPERLIPIDEMIA COMPRISING OXYNTOMODULIN
The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin...
SCAFFOLDS CONTAINING CYTOKINES FOR TISSUE ENGINEERING
The present disclosure provides biocompatible scaffold that promotes M1 or M2 macrophage phenotypes so as to increase vascularization or healing. Also provided...
METHOD OF REDUCING ANTIGENIC DRIFT OR REASSORTMENT OF VIRUSES IN A HOST
ANIMAL USING ALPHA INTERFERON
This disclosures relates to methods of preventing or reducing antigenic drift, viral reassortment and symptoms of wild-type and mutant influenza viruses in a...
TREATMENT OF MOOD AND STRESS RELATED DISORDERS
A pharmaceutical composition and method for treating or attenuating a mood or stress-related disorder in a subject having normal or low inflammatory state is...
LIPID NANOPARTICLES FOR WOUND HEALING
The present invention refers to lipid nanoparticles comprising a growth factor and/or an antimicrobial peptide and to the method for their preparation....
CONTROLLED-RELEASE APOPTOSIS MODULATING COMPOSITIONS AND METHODS FOR THE
TREATMENT OF OTIC DISORDERS
Disclosed herein are compositions and methods for the treatment of otic disorders with anti-apoptotic agent or pro-apoptotic agent compositions and...
USE OF ARPIN A NEW INHIBITOR OF THE ARP2/3 COMPLEX FOR THE DIAGNOSIS AND
TREATMENT OF DISEASES
The present invention relates to the diagnostic and therapeutic uses of Arpin, a protein from the Uncharacterized Protein Family UPF0552, which is a new...
New Use of Cell-Permeable Peptide Inhibitors of the JNK Signal
Transduction Pathway for the Treatment of...
The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-Jun amino terminal...
POLYPEPTIDE TARGETING TO MITOCHONDRIA
Methods for delivering non-mitochondrial proteins to mitochondria are provided. Also provided are nucleic acid constructs comprising a coding sequence encoding...
Anti- P2X7 Peptides and Epitopes
The invention relates to the identification of a novel epitope on non-function P2X.sub.7 receptors which are implicated in cancer. The epitope includes a...
PAN-ANTIVIRAL PEPTIDES FOR PROTEIN KINASE INHIBITION
A method of inhibiting protein kinases by administering polypeptides derived from alpha-neurotoxin, and inhibiting protein kinases. Diseases treated thereby...
DESIGNED PEPTIDES FOR TIGHT JUNCTION BARRIER MODULATION
According to aspects illustrated herein, there is provided an agent that transiently disrupts claudin-1 within tight junctions. The agent includes a peptide...
Application of recombinant immunoregulatory protein of ganoderma lucidum
in preparation of drug for treating...
An application of a recombinant immunoregulatory protein of ganoderma lucidum (rLZ-8) expressed by Pichia pastoris in a preparation of a drug for treating...
GIP AND GLP-1 CO-AGONIST COMPOUNDS
The present invention relates to dual incretin peptide mimetic compounds that agonize receptors for both human glucose-dependent insulinotropic polypeptide...
THERAPEUTIC COMPOSITIONS INCLUDING IRON CHELATORS AND USES THEREOF
Disclosed herein are methods and compositions for the treatment and/or prevention of diseases or conditions comprising administration of at least one iron...
METHODS AND COMPOSITIONS FOR THE TREATMENT OF AMYOTROPHIC LATERAL
The present invention provides, among other things, methods of treating amyotrophic lateral sclerosis including administering to a subject suffering from...
METHODS FOR PREVENTING OR TREATING METABOLIC SYNDROME
The invention provides methods of preventing or treating metabolic syndrome in a mammalian subject. The methods comprise administering to the subject an...
COMPOSITIONS AND METHODS FOR MODULATING DNA METHYLATION
Disclosed herein are compositions and methods for modulating DNA methylation of one or more gene promoters, treating a subject diagnosed with or suspected of...
Vegetarian Capsules Containing Supercritical Herbal Extracts
A capsule with a shell and a fill phase. The fill phase contains less than about 5% beeswax by weight of the capsule and a supercritical extract of an herb....
COMPOSITIONS AND METHODS FOR ENHANCING BRAIN FUNCTION
A nutritional supplement composition enhances cognitive function and includes huperzine A, vinpocetine, acetyl-L-carnitine, and rhodiola. The composition is...
Composition with anoxia-tolerant and anti-fatigue effects and use thereof
A composition with anoxia-tolerant and anti-fatigue functions, which is prepared by the following active ingredients: Arillus Longan, Fructus Jujubae, Radix...
A Purified Extract isolated from Pseudolysimachion rotundum var.
subintegrum containing abundant amount of...
A method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of Pseudolysimachion rotundum...
ASTRAGALUS MEMBRANACEUS SEED RAW OIL, REFINED OIL, PREPARATION METHOD
THEREFOR AND USE THEREOF
The invention belongs to the field of traditional Chinese medicine (TCM), and in particular relates to an astragalus membranaceus seed raw oil and refined oil...
EFFICIENT LIPID DELIVERY TO HUMAN TEAR FILM USING A SALT-SENSITIVE
Provided herein are low salt ophthalmic pharmaceutical composition and methods of use thereof, for example, in the treatment of dry eye syndrome.
FOOD, BEVERAGE OR PHARMACEUTICAL COMPOSITION CONTAINING FERMENTED EASTERN
PRICKLY PEAR AND A PREPARATION METHOD...
Provided is a food or drink composition for improving reflux esophagitis or skin diseases, containing fermented Eastern prickly pear.
IMPROVED ADENOVIRUS FORMULATIONS
This disclosure provides pharmaceutical adenovirus formulations, in particular, liquid pharmaceutical formulations comprising adenoviruses.
Treatment and Prophylaxis for Parkinson's Disease
A method of preventing, mitigating or treating Parkinson's Disease that includes administering an effective amount of a medicament comprised of Lactobacillus...
PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR
MODULATION OF THE MICROBIOME
Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally...
Compositions and Methods
Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of...
COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER USING BACTERIA
Provided herein are compositions comprising substantially non-viable Gram-negative bacterial organisms that have a substantial reduction in endotoxin activity...
ANTI-INFLAMMATORY COMPOSITIONS, METHODS AND USES THEREOF
Described herein are anti-inflammatory fractions and compounds, medicaments, methods and uses thereof. The fraction may be obtained from honey. The fraction...
PHARMACEUTICAL COMPOSITION COMPRISING SILKWORM AS AN ACTIVE INGREDIENT FOR
PREVENTION AND TREATMENT OF TISSUE...
The present invention relates to a pharmaceutical composition for the prevention and treatment of tissue injury caused by irradiation which comprises silkworm...
BIOMOLECULAR GROUP RELATED TO CELL ANTI-AGING
Disclosed is a novel process for producing a Muse cell-like cell or a novel method for extending the replicative life span of a cell population. Provided is a...
COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION
The present invention relates to methods and compositions for providing hematopoietic function to human patients in need thereof, by selecting a pool of...
METHOD OF TREATMENT UTILIZING AN ACELLULAR AMNION DERIVED THERAPEUTIC
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic...
Induced Hepatocytes and Uses Thereof
Disclosed herein are induced hepatocytes from a trophoblast stem cell, methods for inducing the cells, and compositions thereof. Also disclosed herein are...
METHODS OF TREATING OR PREVENTING RHEUMATIC DISEASE
The present disclosure provides a method for treating or preventing a rheumatic disease, comprising administering a population of cells enriched for...
USE OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF ORAL INFLAMMATION
Provided are methods employing of mesenchymal stem cells (MSCs) to prevent, mitigate and/or reverse oral inflammatory conditions, particularly chronic,...
MSCS IN THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES
The present invention relates to, inter alia, methods for culturing mesenchymal stem cells (MSCs) (without the use of non-human serum components), MSCs and...
MODIFIED HEPATITIS POST-TRANSCRIPTIONAL REGULATORY ELEMENTS
Provided are polynucleotides containing a modified PRE having a variant X gene that includes one or more stop codons not present in an unmodified, such as...
PHARMACEUTICAL COMPOSITIONS COMPRISING SODIUM META ARSENITE FOR TREATMENT
OF MULTIPLE MYELOMA
The present application relates to pharmaceutical compositions and methods for treatment of urogenital diseases and bone metastasis in a human, which...
Oral Rehydration Solution
Provided herein are oral rehydration compositions useful for treating a dehydrated subject. Exemplary compositions provided herein are oral rehydration...
Oral Delivery Product
This invention provides a nutritional supplement composition which is a vitamin mint that can be taken anytime or anywhere without water or other liquid which...
Compositions Containing Nucleosides and Manganese and Their Uses
This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine or pyrimidine...