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Patent # Description
2016/0206725 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION
A method of vaccination or immunisation involving the use of a photosensitizing agent, an antigenic molecule, e.g. a vaccine component, and an agent which...
2016/0206724 Methods and Compositions Related to Reorganization of Arenavirus Genome for Development of Novel Arenavirus...
Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.
2016/0206723 BACTERIAL ARTIFICIAL CHROMOSOMES
The invention relates to the use of a bacterial artificial chromosome (BAC) for the preparation of a vaccine, wherein the BAC comprises an inducible bacterial...
2016/0206722 IMMUNOGENIC COMPOSITIONS AND METHODS FOR PIGEON FEVER
The disclosure provides for immunogenic compositions against Pigeon Fever, and methods for their use and preparation. The immunogenic compositions, in...
2016/0206721 BACTERIAL VACCINE AND METHODS FOR MANUFACTURE THEREOF
Disclosed are stable conjugate vaccine formulations for protection against Salmonella typhi, and methods of conjugation between Vi-polysaccharide of S. typhi...
2016/0206720 Potomac Horse Fever Isolates
The present invention discloses novel isolates of Neorickettsia risticii, compositions comprising such isolates, vaccines and methods for using such vaccines...
2016/0206719 COMBINATION OF VACCINATION AND INHIBITION OF THE PD-1 PATHWAY
The present invention relates to a vaccine/inhibitor combination comprising an RNA vaccine comprising at least one RNA comprising at least one open reading...
2016/0206718 Compositions for Liquidation of Tumors
This invention relates to compositions and methods for immunotherapy of cancer. Specifically, a method of cancer immunotherapy is described which results in...
2016/0206717 STIMULATION OF IMMUNITY TO ENDOTHELIAL CELLS, ENDOTHELIAL-LIKE CELLS, AND INTRATUMOR VASCULAR CHANNELS DERIVED...
Disclosed are compositions of matter, methods, and protocols useful for treatment of cancer through induction of anti-angiogenic immune responses. The...
2016/0206716 COMPOSITIONS COMPRISING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF
The present invention provides recombinant Listeria strains comprising an angiogenic factor, recombinant polypeptides comprising an angiogenic factor...
2016/0206715 SPECIFIC MULTIVALENT VIRUS-LIKE PARTICLE VACCINES AND USES THEREOF
The invention provides a VLP free of a viral genome comprising two or more display polypeptides, nucleic acid molecules, polymers of the nucleic acid,...
2016/0206714 Diagnostic Test and Treatment/Prevention of Alzheimer's Disease
The present invention includes a method for diagnosis and treatment and prevention of Alzheimer's Disease comprising obtaining a biological sample from a...
2016/0206713 CELL-PENETRATING BACTERIAL E3-UBIQITIN-LIGASES FOR USE IN IMMUNOTHERAPY
The present invention relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella...
2016/0206712 METHODS FOR TREATING BREAST AND OTHER CANCERS BY TARGETING ARGININOSUCCINATE SYNTHETASE 1-DEFICIENCY
Autophagy is the principal catabolic response to nutrient starvation. However, excessive autophagy can be cytotoxic or cytostatic, and contribute to cell...
2016/0206711 Treatment of Mammalian Physiological Reaction of IgE Antibodies Present in Said Mammal Upon Contact with the...
A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with...
2016/0206710 PHARMACEUTICAL LIQUID COMPOSITION OF BOTULINUM TOXIN WITH IMPROVED STABILITY
Disclosed herein is a liquid pharmaceutical composition of botulinum toxin which is improved in stability. It comprises botulinum toxin, polysorbate 20, and...
2016/0206709 ANTIMICROBIAL COMPOSITION COMPRISING PYROGENIC SILICA AND SERRATHOPEPTIDASE AND USES THEREOF
Methods are provided for treatment of wounds using a complex antimicrobial sorption composition possessing the necrolytic effect for treating the purulent...
2016/0206708 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SYMPTOMS OF WILLIAMS SYNDROME
A therapeutic composition for the treatment of the symptoms of Williams Syndrome and the method for preparing the therapeutic agents is disclosed. The...
2016/0206707 LACTOFERRIN FOR THE TREATMENT OF IBD ASSOCIATED WITH BACTERIAL INVASION
The present invention relates to a substance and an oral formulation for modified release dosage for use in the treatment of inflammatory bowel disease due to...
2016/0206706 SCALABLE MANUFACTURING PLATFORM FOR VIRAL VECTOR PURIFICATION AND VIRAL VECTORS SO PURIFIED FOR USE IN GENE THERAPY
Methods for preparing highly purified AAV vector formulations are provided. The highly pure AAV formulations described herein are superior for clinical use.
2016/0206705 ANTIVIRAL ACTIVITY OF GAS6 INHIBITOR
Compositions and methods are provided for treating viral infection in a mammal by administering a therapeutic dose of a pharmaceutical composition that...
2016/0206704 METHOD
A method of using a vector comprising a transgene to treat a disease or condition of the eye, the method comprising the steps: (a) administering a solution to...
2016/0206703 METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS
This invention provides compositions comprising a protein and an omega-3 fatty acid, method for treating diabetes mellitus, comprising administering same, and...
2016/0206702 PEGylated Recombinant Human Growth Hormone Compounds
A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modified...
2016/0206701 Formulation comprising a stabilized complex of corticotropin releasing hormone and alpha-2 macroglobulin
The present invention relates to a CRH formulation having improved stability/efficacy. The improved CRH formulation is particularly suitable for treatment of...
2016/0206700 METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE
The present invention provides a method of ameliorating inflammation, inhibiting proinflammatory cytokine and/or chemokine expression and treating various...
2016/0206699 USE OF INTERLEUKIN 10 MRNA TRANSFECTED MACROPHAGES IN ANTI-INFLAMMATORY THERAPIES
The present invention relates to the field of cell-based therapeutics. Specifically, the invention is concerned with a composition comprising a macrophage...
2016/0206698 USE OF COMPOUNDS WITH THROMBOPOIETIC ACTIVITY TO PROMOTE BONE GROWTH AND HEALING
TPO was used to promote the growth of bone in both rats and in mice. Gaps in both mouse and in rat bones were treated with a scaffold sized to fit the gap....
2016/0206697 REDUCING THE RISK OF MAJOR ADVERSE CARDIAC EVENTS
This document provides methods and materials for reducing the risk of major adverse cardiac events. For example, methods and materials for identifying patients...
2016/0206696 METHOD OF REPAIRING AGE AND DISEASE IMMUNE DYSFUNCTION AND CELLULAR SENESCENCE WITH LYMPHOID STEM CELLS AND...
This invention relates to methods for treatment of diseases of ageing including immunosenescence, immune dysfunction, inflammation and impairment of early...
2016/0206695 CHIMERIC FIBROBLAST GROWTH FACTOR (FGF) 2/FGF1 PEPTIDES AND METHODS OF USE
The present disclosure provides chimeric proteins having an N-terminus coupled to a C-terminus, wherein the N-terminus comprises an N-terminal portion of...
2016/0206694 PEPTIDE COMPOSITION FOR CANCER TREATMENT BY INHIBITING TRPV6 CALCIUM CHANNEL ACTIVITY
The invention includes an isolated peptide comprising all or part of the amino acid sequence: EGKLSSNDTE GGLCKEFLHP SKVDLPR (SEQ ID NO: 1), wherein the peptide...
2016/0206693 SRPX FOR TREATMENT OF CANCER
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an...
2016/0206692 ENGINEERED INTEGRIN BINDING PEPTIDE COMPOSITIONS
Engineered peptides that bind with high affinity (low equilibrium dissociation constant (Kd)) to the cell surface receptors of fibronectin ...
2016/0206691 TREATMENT OF TUMOURS USING PEPTIDE-PROTEIN CONJUGATES
Provided herein are methods for modulating tumour stroma, normalizing tumour vasculature and/or improving vascular function in a tumour, comprising exposing a...
2016/0206690 USE OF TOLL-LIKE RECEPTOR AGONIST FOR TREATING CANCER
The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor...
2016/0206689 AUTOLOGOUS HIV-1 PROTEINS FOR THE TREATMENT OF LATENT HIV-1 INFECTION
A method of reducing a latent HIV-specific memory-CD4+ T cell pool in a subject includes the steps of: preparing at least one HIV-1 protein coding sequence...
2016/0206688 METHODS FOR TREATING BACTEREMIA AND OSTEOMYELITIS USING ORITAVANCIN
Methods of treating bacterial infections in a subject using oritavancin, including bacteremia, osteomyelitis and endocarditis, are disclosed.
2016/0206687 METHODS FOR TREATING BACTERIAL INFECTIONS USING ORITAVANCIN AND POLYMYXINS
Methods of treating bacterial infections in a subject using a synergistic combination of oritavancin and a polymyxin are disclosed.
2016/0206686 Treatment of Constipation-Predominant Irritable Bowel Syndrome
The invention provides methods for treating a patient with constipation-predominant irritable bowel syndrome by administering a therapeutically effective dose...
2016/0206685 EXTRACTS AND BEVERAGES CONTAINING 2,5-PIPERAZINEDIONE, 3,6-BIS(PHENYLMETHYL)-, (3S,6S)-
Extracts or beverages whose ratio between the content of 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S)-(unit: .mu.g/100 g) and Brix (Bx) is 6 (.mu.g/100...
2016/0206684 POLYMYXIN DERIVATIVES AND USES THEREOF
The present invention relates to a polymyxin derivative of formula (I) ##STR00001## wherein R1 is Dab R2 is Thr R3 is DThr R4 is Dab R5 is Dab R6 is DPhe R7 is...
2016/0206683 INSULIN INDEPENDENCE AMONG PATIENTS WITH DIABETES UTILIZING AN OPTIMIZED HAMSTER REG3 GAMMA PEPTIDE
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
2016/0206682 INSULIN INDEPENDENCE AMONG PATIENTS WITH DIABETES UTILIZING AN OPTIMIZED HAMSTER REG3 GAMMA PEPTIDE
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
2016/0206681 METHOD FOR TREATING COGNITIVE DYSFUNCTION
The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention...
2016/0206680 ANTI-TRYPANOSOME COMPOUNDS AND TREATMENTS
A novel structural class of highly N-methylated linear lipopeptide compounds useful for the treatment of parasitic disease.
2016/0206679 Materials and Methods for Modulating DISC1 Turnover
The invention relates to the finding that turnover of DISC1 (Disrupted in schizophrenia 1) is mediated by the F-box-containing protein FBXW7 (F-box/WD...
2016/0206678 HCV COMBINATION THERAPY
Aspects of this invention include methods comprising administering a combination of a Compound (1) below, including particular crystalline forms thereof and...
2016/0206677 HEALTHCARE FOOD WITH ANTI-DIABETIC EFFECT AND PREPARATION METHOD THEREOF
A healthcare foodstuff having an anti-diabetic effect and effective for treating type 2 diabetes mellitus. The healthcare foodstuff comprises effective...
2016/0206676 ORAL ANTI-PARASITIC COMPOSITION
The present invention relates to a composition for use as an oral anti-parasitic, the composition comprises one or more of an essential oil which contains...
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