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Patent # Description
2016/0206625 MOLYBDENUM COMPOUNDS FOR USE IN THE TREATMENT OF CYANIDE POISONING
The present invention relates to compositions comprising molybdenum compounds, novel molybdenum compounds, kits and methods for their preparation. In...
2016/0206624 MEDICAMENT FOR TREATMENT OF ALZHEIMER'S DISEASE
A medicament for therapeutic and/or preventive treatment of Alzheimer's disease, which comprises a combination of a retinoic acid receptor (RAR) agonist such...
2016/0206623 Composition For Prevention of Vasoactivity in the Treatment of Blood Loss and Anemia
The present invention relates to the prevention of cardiovascular and central nervous system side effects in mammals who receive transfusions of hemoglobin...
2016/0206622 EMULSION FORMULATIONS OF APREPITANT
Disclosed herein are novel pharmaceutical formulations of aprepitant suitable for parenteral administration including intravenous administration. Also included...
2016/0206621 FUSED TRICYCLIC COMPOUNDS AS RAF KINASE INHIBITORS
Provided are certain fused tricyclic compounds and salts thereof, compositions thereof, and methods of use therefor.
2016/0206620 PURIN DERIVATIVES FOR USE IN THE TREATMENT OF FAB-RELATED DISEASES
The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for wound healing preferably in diabetic patients.
2016/0206619 INHIBITION OF ADAPTOR ASSOCIATED KINASE 1 FOR THE TREATMENT OF PAIN
This invention is directed to the treatment of pain by inhibiting adaptor associated kinase 1 (AAK1). Numerous AAK1 inhibitors are disclosed.
2016/0206618 COMPOSITIONS AND METHODS INVOLVING POLYMER, SOLVENT, AND HIGH VISCOSITY LIQUID CARRIER MATERIAL
Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent....
2016/0206617 COMPOSITIONS AND THERAPEUTIC METHODS FOR ACCELERATED PLAQUE REGRESSION
The invention comprises methods for treating and/or preventing cardiovascular, cholesterol, and lipid related disorders, including atherosclerosis, through...
2016/0206616 DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS
Provided herein are dihydropyrimidine compounds and their pharmaceutical applications, especially for use in treating and preventing HBV diseases. ...
2016/0206615 NANOPARTICLE DRUG DELIVERY SYSTEM AND METHOD OF TREATING CANCER AND NEUROTRAUMA
The invention provides pharmaceutical formulations of inhibitors for poly (ADP-ribose) polymerase (PARP) enzyme. The formulations can be used in the treatment...
2016/0206614 SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their...
2016/0206613 INHIBITORS OF ACTIVIN-LIKE RECEPTOR KINASES
The claimed invention is directed to a method for screening a compound that binds to an allosteric site of ALK2, the method comprising screening for a compound...
2016/0206612 ORAL FORMULATIONS AND LIPOPHILIC SALTS OF METHYLNALTREXONE
The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
2016/0206611 APOPTOSIS-INDUCED AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases...
2016/0206610 METHODS FOR TREATING AND/OR PREVENTING EMESIS AND/OR NAUSEA INCLUDING ACUTE AND/OR DELAYED NAUSEA AND/OR ACUTE...
Methods for treating and/or preventing nausea and emesis including acute and/or delayed nausea and/or acute and/or delayed emesis in a subject are provided...
2016/0206609 NEUROPROTECTIVE POLYPHENOL ANALOGS
The present invention provides neuroprotective polyphenol compounds, which can be synthetic analogs of fisetin, baicalein or chlorogenic acid, that maintain...
2016/0206608 CRIZOTINIB FOR USE IN THE TREATMENT OF CANCER
The present invention relates to the use of ROS kinase inhibitors for treating abnormal cell growth in mammals. In particular, the invention provides methods...
2016/0206607 Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione
Pharmaceutical compositions and single unit dosage forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, or a pharmaceutically acceptable...
2016/0206606 TOPICAL COMPOSITIONS COMPRISING A THIAZOLIDINEDIONE
Provided herein are compositions comprising a thiazolidinedione compound or pharmaceutically acceptable salt thereof, an alcohol (e.g., a monohydroxy alcohol),...
2016/0206605 COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR
The present invention provides a screening assay for identifying inhibitors of Pseudomonas aeruginosa CFTR Inhibitory Factor as well as compositions and...
2016/0206604 FORMULATIONS COMPRISING WETTING AGENTS AND COMPOUNDS FOR THE MODULATION OF HEMOGLOBIN (S)
This invention provides pharmaceutical formulations for the allosteric modulation of hemoglobin (S) and methods for their use in treating disorders mediated by...
2016/0206603 COMPOSITION COMPRISING TORASEMIDE AND BACLOFEN FOR TREATING NEUROLOGICAL DISORDERS
The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid .beta....
2016/0206602 COMPOSITIONS AND METHODS FOR ENHANCING BRAIN FUNCTION
Compositions and methods are provided that enhance cognition in a human to which the composition is orally administered. Remarkably, clinical studies have...
2016/0206601 Methods and Compositions for Re-activating Epstein-Barr Virus and Screening Compounds Therefor
In an effort to discover therapies for treating diseases caused by EBV, a novel screening assay for identifying compounds that reactivate EBV latent infection...
2016/0206600 ADHESIVE COMPOSITION FOR CARRYING THERAPEUTIC AGENTS AS DELIVERY VEHICLE ON COATING APPLIED TO VASCULAR GRAFTS
Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular...
2016/0206599 OCULAR FORMULATIONS FOR DRUG-DELIVERY AND PROTECTION OF THE ANTERIOR SEGMENT OF THE EYE
The present application relates to topical formulations comprising Compound-I ##STR00001## or its free base, and a second active agent selected from nicotinic...
2016/0206598 THERAPEUTIC AGENT FOR DYSLIPIDEMIA
This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemia states, such as...
2016/0206597 New Use
The present invention relates to methods and pharmaceutical compositions for renal protection in a mammal in need thereof, such as a mammal having a disease...
2016/0206596 Anti-depression Compounds
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and...
2016/0206595 INDOLE-3-ALDEHYDE FOR TREATING DYSREACTIVE IMMUNE DISORDERS
The therapeutic use of bacteria, specifically but not only lactobacilli, which produce indole-3-aldehyde, or directly of indole-3-aldehyde itself, is proposed...
2016/0206594 Pro-Neurogenic Compounds
This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from...
2016/0206593 PHARMACEUTICAL FOR PROPHYLAXIS OR TREATMENT OF HYPERTENSION
A pharmaceutical for the prophylaxis or treatment of hypertension or a disease derived from hypertension. The pharmaceutical is characterized by comprising (i)...
2016/0206592 METHOD FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS BY INHIBITION OF CXCR4/CXCL12 SIGNALING
The present invention provides use of an inhibitor of G protein-coupled receptor CXCR4 for treating amyotrophic lateral sclerosis (ALS), for inhibiting...
2016/0206591 TREATMENTS FOR FIBROTIC DISEASES
Disclosed herein are methods for treatment for fibrosis, ocular pathologies associated with fibrosis, including proliferative vitreoretinopathy (PVR) by...
2016/0206590 BPO WASH EMULSION COMPOSITION
A topical dermatological/pharmaceutical composition is described that includes BPO wherein the composition is a wash composition with desirable tolerance,...
2016/0206589 PHARMACEUTICAL USE OF 3-BENZYLSULFONYLPROPIONITRILE
The present invention is directed to a method of treating an inflammatory skin disease or disorder, such as dermatitis, psoriasis, acne, or rosacea. The method...
2016/0206588 STABILIZED FORMULATIONS OF FATTY ACIDS
Disclosed herein are stabilized powder and aqueous formulations comprising a substantially water insoluble lipophilic bioactive compound and a micelle-forming...
2016/0206587 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE FOR ADMINISTRATION AT A LOW DAILY DOSE
The present invention relates to pharmaceutical compositions containing dimethyl fumarate (DMF), More specifically, the present invention relates to a...
2016/0206586 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE FOR ADMINISTRATION AT A LOW DAILY DOSE
The present invention relates to pharmaceutical compositions containing dimethyl fumarate (DMF). More specifically, the present invention relates to a...
2016/0206585 A COMPOSITION COMPRISING A LIPID COMPOUND, A TRIGLYCERIDE, AND A SURFACTANT, AND METHODS OF USING THE SAME
Compositions comprising 2-((5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenyloxy)butanoic acid, an ester derivative, or a pharmaceutically acceptable salt...
2016/0206584 LEVODOPA AND CARBIDOPA INTESTINAL GEL AND METHODS OF USE
The present disclosure relates to (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent (b) methods of...
2016/0206583 AMINO ACID TREATMENT OF SEIZURES
Methods for treating or preventing a seizure in a subject by administering to the subject a therapeutically effective amount of at least one D-amino acid or...
2016/0206582 ENHANCER OF SURVIVAL OF TRANSPLANTED ORGAN
The present invention provides an agent for promoting graft survival which can suppress rejection without use of existing immunosuppressants, an organ...
2016/0206581 TREATMENT AND PREVENTION OF AUTISM AND AUTISM SPECTRUM DISORDERS
In some embodiments, the present invention provides certain compositions and methods that may be useful in the treatment and/or prevention of a ...
2016/0206580 MULTIVESICULAR LIPOSOME FORMULATIONS OF TRANEXAMIC ACID
Some embodiments of the present application are related to multivesicular liposome formulations comprising tranexamic acid (TXA) for the purpose of minimizing...
2016/0206579 TAURINE OR TAURINE-LIKE SUBSTANCES FOR THE PREVENTION AND TREATMENT OF A DISEASE ASSOCIATED WITH RETINAL...
The present invention relates to taurine or taurine-like substances for the prevention and treatment of a disease associated with retinal ganglion cell...
2016/0206578 Aryl-Phenyl-Sulfonamido-Cycloalkyl Compounds and Their Use
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-cycloalkyl compounds...
2016/0206577 NOVEL DRUG FORMULATION
There is provided inter alia a pharmaceutical aqueous nanosuspension comprising (i) 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluorobenzamide in nanoparticulate...
2016/0206576 N-ACETYLCYSTEINE AMIDE (NAC AMIDE) IN THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human...
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