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Patent # Description
2016/0213677 NEW COMPOUNDS
The invention relates to new pyridopyrazine and naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for...
2016/0213676 Substituted 2,3-dihydro-1H-inden-1-one Retinoic acid-related orphan nuclear receptor Antagonists for Treating...
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic...
2016/0213675 Triazine Compounds and Compositions Thereof and Methods for Treating Malaria and Chemoprophylaxis
Disclosed herein are triazine compounds and methods of making and using thereof to treat malaria, provide chemoprophylaxis, and/or treat or inhibit infection...
2016/0213674 PDE9 Inhibitors with Imidazo Triazinone Backbone
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically...
2016/0213673 ENDURANCE FORMULATION AND USE
The present disclosure provides compositions and formulations containing dihydrocapsiate, caffeine and arginine as well as methods of making and using the...
2016/0213672 Combination
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method...
2016/0213671 PROPHYLAXIS AND TREATMENT OF A NEURODEGENERATIVE DISEASE NOT BASED ON A PROTEIN-FOLDING DISORDER
The present invention relates to substances for the prophylaxis and treatment of a neurodegenerative disease which is not based on a protein-folding disorder....
2016/0213670 BICYCLIC HETEROARYL CYCLOALKYLDIAMINE DERIVATIVES AS INHIBITORS OF SPLEEN TYROSINE KINASES (SYK)
The present invention relates to bicyclic heteroaryl cycloalkyldiamine derivatives, to processes for their production, to their use as SYK inhibitors and to...
2016/0213669 USE OF N-(4-((3-(2-AMINO-4-PYRIMIDINYL)-2-PYRIDINYL)OXY)PHENYL)-4-(4-METHY- L-2-THIENYL)-1-PHTHALAZINAMINE IN...
The present invention relates to methods of using AMG 900, a small molecule pan aurora kinase inhibitor, in combination with histone deacetylase (HDAC)...
2016/0213668 Compounds for use in Treatment of Mucostis
The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof,...
2016/0213667 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES
The invention described herein relates to methods for treating mitochondrial diseases. In particular, the invention relates to methods for treating...
2016/0213666 NOVEL COMPOUND USEFUL FOR THE TREATEMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
A pyrazolopyridine compound according to Formula I, able to inhibit JAK is disclosed, as well as pharmaceutically acceptable salts, a solvate thereof, solvates...
2016/0213665 SOLUTION FOR ORAL ADMINISTRATION
Provided is a solution for oral administration of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (compound (I)) or a salt thereof,...
2016/0213664 TREATMENT OF CEREBRAL CAVERNOUS MALFORMATIONS AND CEREBRAL ANEURYSMS WITH RHO KINASE INHIBITORS
Provided are methods of treating a cerebral cavernous malformation (CCM) and methods of treating cerebral aneurysm in a mammal with certain Rho kinase inhibitors.
2016/0213663 TREATMENT OF LUPUS ARTHRITIS USING LAQUINIMOD
This invention provides a method of treating a subject afflicted with active lupus arthritis comprising periodically administering to the subject an amount of...
2016/0213662 METHODS AND DEVICES FOR THE TREATMENT OF OCULAR DISEASES IN HUMAN SUBJECTS
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject...
2016/0213661 Use of 4-Aminopyridine to Improve Neuro-Cognitive and/or Neuro-Psychiatric Impairment in Patients with...
Disclosed herein are methods and compositions related to use of aminopyridines, such as 4-aminopyridine, to improve the neuro-cognitive impairments and related...
2016/0213660 PHENYL DERIVATIVE
The compound of the formula (I-1): ##STR00001## wherein all the symbols have the same meanings as described in the specification, has two cyclic groups,...
2016/0213659 TREATMENT OF BURN PAIN BY TRPV1 MODULATORS
The present invention is directed to a method for treating pain associated with a burn injury originating from a thermal exposure, from a radiation exposure,...
2016/0213658 PHARMACEUTICAL COMPOSITIONS OF ROFLUMILAST AND PROCESS FOR PREPARATION THEREOF
The present invention relates to pharmaceutical compositions of roflumilast. More particularly, the present invention relates to pharmaceutical tablet...
2016/0213657 PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PULMONARY DISEASE
Provided is a pharmaceutical composition containing, as an active ingredient thereof, a substituted biaryl compound represented by general formula (I),...
2016/0213656 HYOSCYAMINE DOSAGE FORM
A method of alleviating or treating a condition which can be alleviated or treated by administering hyoscyamine comprises administering to a subject in need...
2016/0213655 1,6- DIAZABICYCLO [3,2,1] OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. ##STR00001##
2016/0213654 BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS
The present invention relates to bicyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment...
2016/0213653 HETEROCYCLIC ITK INHIBITORS FOR TREATING INFLAMMATION AND CANCER
Disclosed herein are heterocyclic compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of...
2016/0213652 Cyclic Ether Pyrazol-4-YL-Heterocyclyl-Carboxamide Compounds And Methods Of Use
Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically...
2016/0213651 PIDOTIMOD FOR USE IN THE TREATMENT OF INFLAMMATION-ASSOCIATED DISEASES
The present invention relates to a novel use of the active ingredient Pidotimod, or its stereoisomers and/or physiologically acceptable salts thereof, to treat...
2016/0213650 COMBINATIONS OF SOLIFENACIN AND SALIVARY STIMULANTS FOR THE TREATMENT OF OVERACTIVE BLADDER
Disclosed herein are pharmaceutical compositions comprising a therapeutically effective amount of extended release solifenacin, or a pharmaceutically...
2016/0213649 Compositions And Methods Of Treatment Of Inflammatory Skin Conditions Using Allantoin
Embodiments herein provide formulations and methods for treatment of inflammatory skin diseases using allantoin in an amount from about 0.5% to about 15.0% by...
2016/0213648 Tetrazolones as a Carboxylic Acid Bioisosteres
The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to...
2016/0213647 COMPOSITIONS AND METHODS FOR INHIBITING VIRAL INFECTION
Compositions and methods for inhibiting viral protein production, viral infection, and viral replication in a host or host cells infected with a virus (e.g.,...
2016/0213646 NEW USE
The present invention relates to methods and pharmaceutical compositions for the prevention or in delaying time to first occurrence of mortality, in particular...
2016/0213645 COMBINATION OF LEVETIRACETAM AND A BETA-SECRETASE (BACE) INHIBITOR
This invention is a pharmaceutical composition for the treatment and prevention of disease comprising of levetiracetam, as an active ingredient, to stabilize...
2016/0213644 Regulation of Body Weight Gain By Using Dibenzo-Alpha-Pyrones
A method of using dibenzo-alpha-pyrones (DBPs) is provided wherein a subject is administered one or more of the aforementioned resulting in decreased body...
2016/0213643 Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and...
Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example,...
2016/0213642 NUTRACEUTICAL COMPOSITION FOR PDE4 INHIBITION, ENHANCED DOPAMINE METABOLISM AND LONG TERM POTENTIATION
A nootropic combination for increasing cognitive functioning. The combination includes a phosphodiesterase 4 inhibitor and a cyclic adenosine monophosphate...
2016/0213641 Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and...
Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example,...
2016/0213640 ANTICANCER AGENT COMPRISING AMINOACETONITRILE COMPOUND AS ACTIVE INGREDIENT
The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active...
2016/0213639 COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS
Compositions and methods for the treatment of non-alcoholic steatohepatitis and related disorders are provided herein, for example in women under 50 or...
2016/0213638 POLYENOLIC ZINC-BINDING AGENTS (PEZBINS) ACTIVELY PROMOTE INACTIVATION OF CANCER STEM CELLS AND POTENTIATE...
The present invention provides a method of inhibiting the growth of or promoting differentiation and destruction of cancer stem cells (CSCs) comprising...
2016/0213637 Use of Glyceryl Trinitrate for Treating Traumatic Edema
Use of glyceryl trinitrate (GTN) for treating traumatic edemas.
2016/0213636 STABLE PHARMACEUTICAL COMPOSITION AND METHODS OF USING SAME
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or...
2016/0213635 COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER
The invention relates to compounds of general formula (I): CH.sub.3--(CH.dbd.CH).sub.n--R (I) wherein n=3, 5, 7; R is selected from --CO--OR', --CO--O.sup.(-),...
2016/0213634 CARCINOMA DIAGNOSIS AND TREATMENT, BASED ON ODC1 GENOTYPE
The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other...
2016/0213633 METHOD OF INDUCING ANTI-GLATIRAMER ACETATE ANTIBODY RESPONSE
The present invention provides methods of inducing anti-glatiramer acetate specific antibodies in a human subject afflicted with multiple sclerosis, comprising...
2016/0213632 Memory Performance and Prevention and Treatment of Neurodegenerative Diseases
The present technology relates to improvement of memory performance and the prevention or treatment of brain disorders associated with memory loss. In...
2016/0213631 INTRAVENOUS BACLOFEN FORMULATIONS AND TREATMENT METHODS
An intravenous baclofen solution is disclosed, along with methods of dosing and treatment therewith.
2016/0213630 CLONIDINE AND GABA COMPOUNDS IN A BIODEGRADABLE POLYMER CARRIER
Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine and a gamma-aminobutyric...
2016/0213629 METHOD FOR ENHANCING ENERGY PRODUCTION AND METABOLISM IN CELLS
The present invention relates to use of a composition comprising D-glyceric acid (DGA), DL-glyceric acid, L-glyceric acid, or hydroxypyruvatic acid and/or...
2016/0213628 DETERRING ABUSE OF PHARMACEUTICAL PRODUCTS AND ALCOHOL
A therapeutic dosage form includes a pharmaceutically active ingredient, a crosslinked polyacid, and a linear polyacids. The crosslinked polyacid is insoluble...
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