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Patent # Description
2016/0220542 SYNERGISTIC ACTIVITY OF MODULATORS OF THE NO METABOLISM AND OF NADPH OXIDASE IN THE SENSITISATION OF TUMOR CELLS
Herein disclosed are pharmaceutical compositions that contain a pharmaceutically active amount of at least one active substance that increases the available NO...
2016/0220541 COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions...
2016/0220540 COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions...
2016/0220539 METHODS AND COMPOSITIONS FOR TREATING ANXIETY
Methods of treating a TRPC5 mediated disorder in a subject by administering an effective amount of a TRPC5 antagonist, such as a compound disclosed herein, are...
2016/0220538 IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING
This invention relates, e.g., to a method for enhancing exon skipping in a pre-mRNA of interest, comprising contacting the pre-mRNA with an effective amount of...
2016/0220537 COMPOSITIONS TO IMPROVE THE THERAPEUTIC BENEFIT OF BISANTRENE AND ANALOGS AND DERIVATIVES THEREOF
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal...
2016/0220536 USE OF PHENYLMETHIMAZOLES, METHIMAZOLE DERIVATIVES, AND TAUTOMERIC CYCLIC THIONES FOR THE TREATMENT OF...
Treatment of autoimmune and/or inflammatory diseases associated with overexpression of Toll-like receptor 3 (TLR3) as well as Toll-like receptor 4 (TLR4)...
2016/0220535 INDOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
Substituted indole derivatives of formula (I) ##STR00001## wherein the radicals have e. g. the following meaning: R.sup.1 is hydrogen, --C.sub.1-6-alkyl, R.sup.2...
2016/0220534 Rapid Disperse Dosage Form Containing Levetiracetam
A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of levetiracetam in a porous matrix that disperses in water...
2016/0220533 USE OF L-TRYPTOPHAN FOR THE TREATMENT OF PARASOMNIAS
Described is the use of L-tryptophan for treating a subject with parasomnia and associated methods of treating a subject with parasomnia. Optionally, the...
2016/0220532 METHODS AND COMPOSITIONS FOR AMELIORATING PANCREATIC CANCER
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for...
2016/0220531 METHODS AND COMPOSITIONS TO ENHANCE BONE GROWTH COMPRISING A STATIN
Implantable medical devices and methods are provided that have one or more statins disposed therein. The medical devices may be implanted at near or in a bone...
2016/0220530 Preparation and Use of a Composition for Prevention and Mitigation of the Effects of Radiation
Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise ...
2016/0220529 USE FOR CANNABINOID
The invention relates to the use of one or more cannabinolds in the manufacture of medicaments for use in the treatment of diseases and conditions benefiting...
2016/0220528 TOPICAL PHARMACEUTICAL FORMULATIONS CONTAINING A LOW CONCENTRATION OF BENZOYL PEROXIDE IN SUSPENSION IN WATER...
An aqueous formulation for topical application to the skin comprising water, a water-miscible organic solvent, and benzoyl peroxide, wherein the concentration...
2016/0220527 KINASE INHIBITORS FOR THE TREATMENT OF CANCER
The present invention relates to kinase inhibitors for the treatment of cancer. Specifically, the present invention relates to the use of aminoactonitrile...
2016/0220526 METHOD OF TREATING OR PREVENTING TUMORS USING 1-(ALKYLSULFINYL)-2-ISOTHIOCYANATOALKYL-1-ALKENE
A method of treating or preventing human or mammalian cancer and tumor including administering to a patient or an animal in need thereof a pharmaceutical...
2016/0220525 USE OF NOVEL MONOSACCHARIDE-LIKE GLYCYLATED SUGAR ALCOHOL COMPOSITIONS FOR DESIGNING AND DEVELOPING...
This invention is related to a novel sugar-like chemical composition and its use for diabetes therapy. Particularly, the present invention teaches the use of...
2016/0220524 COMPOSITIONS OF SMALL MOLECULE THERAPEUTICS
Compositions containing a small molecule therapeutic and an alkyl N,N-disubstituted amino acetate are disclosed. Inclusion of the alkyl N,N-disubstituted amino...
2016/0220523 TREATING NEURODEGENERATIVE DISEASE WITH FENOFIBRATE AND ANALOGS THEREOF
Provided herein are methods of treating or preventing a neurodegenerative by administering fenofibrate or an analog thereof.
2016/0220522 COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in...
2016/0220521 MICROCAPSULE FAT POWDER OF OMEGA-3 ENRICHED MEAT, EGG AND MILK, AND PREPARATION METHOD THEREOF
Disclosed are a microcapsule fat powder of .OMEGA.3-enriched meat, egg and milk and its preparation method, and the powder includes a water-soluble wall...
2016/0220520 APPARATUS, SYSTEM AND METHOD FOR THE TREATMENT OF ATHEROSCLEROSIS, HEART DISEASE AND STROKE
Biocompatible solvents, systems, apparatus and methods are provided for treating atherosclerosis, heart disease and stroke by dissolving and reducing arterial...
2016/0220519 AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN
The invention relates to compounds, to compositions comprising the same and uses thereof for the prevention or treatment of pain, e.g. neuropathic pain while...
2016/0220518 Novel Formulation of Naproxen
The present invention relates to methods for producing particles of naproxen using dry milling processes as well as compositions comprising naproxen,...
2016/0220517 Abuse-proofed oral dosage form
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for...
2016/0220516 Aqueous Pharmaceutical Formulation of Tapentadol for Oral Administration
An aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The...
2016/0220515 METHOD OF REDUCING NEURONAL CELL DEATH WITH HALOALKYLAMINES
The present invention is directed to pharmaceutical compositions and methods of treating traumatic brain injury (TBI). The invention is also directed to...
2016/0220514 COMPOSITIONS FOR OVERCOMING RESISTANCE TO TRAMADOL
Disclosed herein is a composition for oral administration of O-desmethyltramadol that is effective for overcoming resistance to tramadol in patients.
2016/0220513 Application Of R-ketamine And Salt Thereof As Pharmaceuticals
Provided is a novel compound having rapid and long-lasting therapeutic effects on diseases exhibiting depressive symptoms. Specifically, provided are an agent...
2016/0220512 MODIFIED RELEASE PHARMACEUTICAL FORMULATIONS
The present invention relates to modified release compositions comprising plurality of modified release units. Particularly, the modified release units...
2016/0220511 NUTRITIONAL COMPOSITIONS FOR MODULATING INFLAMMATION INCLUDING EXOGENOUS VITAMIN K2
Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, a nutritional composition includes...
2016/0220510 ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS
An aminoacylation/translation (AIT) system based on the protein synthesis system from the pathogen Pseudomonas aeruginosa, was used to screen chemical...
2016/0220509 THERAPEUTIC COMPOSITIONS COMPRISING MONOTERPENES
This invention provides a compositions for transport of a therapeutic agent. The compositions contain a therapeutic agent and a monoterpene or an analog...
2016/0220508 PHARMACEUTICAL COMPOSITION COMPRISING DIPHENYLENEIODONIUM FOR TREATING DISEASES CAUSED BY THE PARASITES...
The invention relates to a new use of diphenyleneiodonium (DPI) as an active substance against parasites of the family Trypanosomatidae, in particular against...
2016/0220507 KIT FOR SUSTAINED TRANSDERMAL DRUG DELIVERY USING LIQUID OR SEMISOLID FORMULATIONS AND METHOD OF USING THE SAME
A kit for sustained transdermal drug delivery using liquid or semisolid drug formulations and methods of using the kit are disclosed. The kit may comprise a...
2016/0220506 Base Composition for Tape Agent
The object of the present invention is to provide a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly...
2016/0220505 COMPOSITIONS COMPRISING LIPOPHILIC ACTIVE COMPOUNDS AND METHOD FOR THEIR PREPARATION
Compositions are provided comprising a lipophilic active compound, e.g., a human or veterinary drug or a nutraceutical, interwoven with a polymeric matrix...
2016/0220504 METHOD FOR PRODUCING AN ADHESIVE MATERIAL FOR MEDICAL APPLICATION
A method is provided for producing an adhesive material (1) for a medical application such as a dressing. The method includes at least one step for coating a...
2016/0220503 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF
A method for the production of biodegradable nanoparticles with an average particle size of less than 400 nm. In a first step, a macromonomer is prepared in a...
2016/0220502 POTATO PROTEIN NANOPARTICLES
This invention provides a nanoparticle made of: a potato protein; and a bioactive compound bound to the potato protein. The invention further provides foods or...
2016/0220501 TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS
Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that...
2016/0220500 Targeting Intracellular Copper Ions for Inhibiting Angiogenesis Using Nanoparticles of Ternary Inorganic Metal...
This invention describes a new type of covalent-network ternary inorganic metal sulfide compounds M.sub.1M.sub.2S.sub.4 (M.sub.1, independently, is, Mg, Ca,...
2016/0220499 BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES
The invention concerns the use of bacterial ghosts as carrier and targeting vehicles for active substances.
2016/0220498 FULLY OR PARTIALLY BIODEGRADABLE DEVICE FOR CONTROLLED DRUG DELIVERY
Present invention provides fully or partially biodegradable device for controlled delivery of drugs. In one embodiment, the present invention relates provides...
2016/0220497 Method For The Therapeutic Treatment Of Keratinous Substrate, Mucous Membrane Or Tooth
The invention relates to a method for the therapeutic treatment of keratinous substrate, mucous membrane or tooth comprising preparing a composition containing...
2016/0220496 IMPLANTABLE MEDICAL DEVICES FOR EXTENDED RELEASE OF THERAPEUTIC AGENTS
The invention pertains to implantable medical devices for controlled delivery of therapeutic agents. Some devices according to the invention have a titanium...
2016/0220495 ACCORDION PILL COMPRISING LEVODOPA FOR AN IMPROVED TREATMENT OF PARKINSON'S DISEASE SYMPTOMS
The invention provides for the use of an accordion pill comprising levodopa for the treatment of symptoms of Parkinson's disease in a subject in need thereof...
2016/0220494 PHARMACEUTICAL COMPOSITIONS CONTAINING REFAMETINIB
The present invention relates to pharmaceutical compositions which contain refametinib, a hydrate, solvate, meta bolite or pharmaceutically acceptable salt...
2016/0220493 ORAL FORMULATIONS OF DEFERASIROX
Orally administerable deferasirox formulations are disclosed having reduced release under gastric conditions and fast release at near neutral pH or at neutral pH.
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