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Patent # Description
2016/0228589 METHODS AND COMPOSITIONS FOR IMAGING DISORDERS USING POLYSPECIFIC AGENTS
The present invention provides compositions and methods for detecting and/or monitoring a disease state with polyspecific imaging agents. In a particular...
2016/0228588 ETHER AND ALKYL PHOSPHOLIPID COMPOUNDS FOR TREATING CANCER AND IMAGING AND DETECTION OF CANCER
Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem...
2016/0228587 LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL...
The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment...
2016/0228586 Compounds and Their Use for Preparation of Tau Imaging Agents and Tau Imaging Formulations
The present invention provides novel trimethylammonium compounds, of the Formula: (I) methods of making these compounds, methods of using the compounds for...
2016/0228585 Formulation, Apparatus and Method for Stabilizing Radiopharmaceuticals
A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas...
2016/0228584 18F -GLUTATHIONE CONJUGATE AS A PET TRACER FOR IMAGING TUMORS OR NEUROLOGICAL DISORDERS THAT OVEREXPRESS L-PGDS...
A PET tracer for imaging tumors or neurological disorders that overexpress L-PGDS enzyme is provided. The present invention have prepared a glutathione...
2016/0228583 Process for the Preparation of Gadobenate Dimeglumine Complex in a Solid Form
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently...
2016/0228582 Pre-Saturation of the Liver and Subsequent Administration of the Contrast Agent
The present invention relates to an aqueous formulation for use in diagnostic detection wherein the aqueous formulation is administered prior to the...
2016/0228581 MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME
Provided are macrocyclic compounds and iron or cobalt coordinated macrocyclic compounds. The compounds can be used as MRI contrast agents. Certain compounds...
2016/0228580 MIXED MICELLES
This disclosure is directed to mixed micelle compositions for administration of e.g., therapeutic agents or imaging agents to a subject.
2016/0228579 LIPID NANOPARTICLES AND USES THEREOF
The present invention relates to lipid-associated indocyanine green particles for enhanced functional high-resolution near-infrared fluorescence medical...
2016/0228578 COATED UP-CONVERSION NANOPARTICLES
The invention provides novel biocompatible upconversion nanoparticle (UCNP) that comprises a core of cubic nanocrystals (e.g., comprising .alpha.-Na Ln.sub.a,...
2016/0228577 TRANSGENIC ANIMALS FOR IN VIVO IMAGING
Compositions, methods and transgenic animals for in vivo detection of ectopically expressed sodium iodide symporter (NIS) are provided.
2016/0228576 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
2016/0228575 NARINGENIN COMPLEXES AND METHODS OF USE THEREOF
The invention relates to methods of treatment of hepatitis C, dyslipidemia, insulin resistance, and inflammation, with flavonoid-sugar complexes.
2016/0228574 PARTICLES WITH MULTIPLE FUNCTIONALIZED SURFACE DOMAINS
This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic...
2016/0228573 LIPOSOME ENCAPSULATED AFFINITY DRUG
The disclosure provides a liposomal antifolate composition comprising a liposome including an interior space, a bioactive antifolate agent disposed within said...
2016/0228572 Immobilised Biological Entities
There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition...
2016/0228571 Anti-DLL3 antibody drug conjugates
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
2016/0228570 Novel Antibody And Use In Diagnosis And Therapy Of Arthropathies
The present invention provides a composition comprising an antibody or fragment thereof against oxidised Collagen II (CII) in which the antibody or fragment...
2016/0228569 PEPTIDE CONSTRUCTS AND WELL-DEFINED AGGREGATES THEREOF
This invention relates to isolated peptides, peptide mimetics and repeat units thereof, which are capable of self-assembly into nano-microparticles or...
2016/0228568 VIRUS-LIKE PARTICLE CONJUGATES FOR DIAGNOSIS AND TREATMENT OF TUMORS
The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles...
2016/0228567 Hypoxia-Targeted Delivery System for Pharmaceutical Agents
Molecular compositions, nanoparticle compositions, and pharmaceutical compositions of the invention provide for the delivery of a polynucleotide to a hypoxic...
2016/0228566 CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a...
2016/0228565 POLYAMIDE BASED PEPTIDODENDRIMER CONJUGATES
The present invention relates to monofunctional and bifunctional peptidodendrimer conjugates that contain a polyamide dendrimer conjugated to Herpes Simplex...
2016/0228564 Phospholipid Ether Analogs as Cancer-Targeting Drug Vehicles
The present invention is directed to therapeutic compounds capable of targeting cancer cells and cancer stem cells. The present invention is further directed...
2016/0228563 LIPIDATED PEPTIDES FOR LOWERING BLOOD GLUCOSE
Lipidated analogs of prolactin-releasing peptides (PrRP) and their use in controlling and lowering blood glucose in mammals is disclosed. Useful compounds...
2016/0228562 MUTUAL PRODRUG COMPRISING SHORT CHAIN FATTY ACIDS AND ZEBULARINE OR 1'-CYANO-CYTARABINE FOR CANCER TREATMENT
The present invention provides mutual prodrugs comprising anti-cancer nucleosides and short chain fatty acids; methods for production of the mutual prodrugs;...
2016/0228561 Protein-Cell Conjugate, Preparation Method and Use Thereof
The present invention pertains to immunology, biomedicine field, specifically relates to a protein-cell conjugate, which is characterized in that the protein...
2016/0228560 INJECTABLE PHARMACEUTICAL COMPOSITIONS FOR SEALING TISSUES
Various embodiments of a pharmaceutical composition for closing or sealing an opening or a bleeding site such as a vascular puncture site following...
2016/0228559 COMPOSITION FOR APPLICATION TO A MUCOSA COMPRISING A CELLULOSE ETHER
A composition designed for application to a mucosa comprises i) a tonicity-adjusting agent, ii) an aqueous liquid diluent, and iii) 0.1 to 6 weight percent of...
2016/0228558 TRANSDISCAL ADMINISTRATION OF SPECIFIC INHIBITORS OF PRO-INFLAMMATORY CYTOKINES
The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
2016/0228557 PERSONAL CARE COMPOSITIONS WITH ACID FUNCTIONAL SILICONE BASED STRUCTURING AGENTS
The invention is directed to personal care compositions comprising an acid functionality bearing silicone neutralized in situ with at least one aminosilane or...
2016/0228556 Radiopaque Polymers
Radiopaque hydrogels, in particular radiopaque hydrogel microspheres, comprising a polymer having 1,2-diol or 1,3-diol groups acetalised with radiopaque species.
2016/0228555 REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions...
2016/0228554 REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions...
2016/0228553 Stabilised Solid Compositions of Factor VII Polypeptides
The invention relates to chemically as well as physically stable compositions comprising Factor VII or a Factor VII-related polypeptide such that these...
2016/0228552 ORAL COMPOSITION COMPRISING A COOLING AGENT
The present invention relates to a formulation comprising an endothermic cooling agent selected from the group consisting of xylitol, sorbitol, mannitol and...
2016/0228551 Method of Treating Disorders using a Pharmaceutical Composition of Oligopeptides
The present invention relates to a pharmaceutical composition of oligopeptides, preferably cyclic oligopeptides, said composition further comprising one or...
2016/0228550 COMPOSITIONS AND METHODS OF PROPHYLAXIS FOR CONTACT DERMATITIS
The present invention relates to compositions and methods for inhibiting metal exposure to tissues.
2016/0228549 Multifunctional Metal Nanoparticles Having A Polydopamine-Based Surface and Methods of Making and Using the Same
The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at...
2016/0228548 NANOPARTICLE DELIVERY SYSTEM FOR TARGETED ANTI-OBESITY TREATMENT
A magnetic nanoparticles including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical...
2016/0228547 CHIMERIC ANTIGEN RECEPTOR TARGETING OF TUMOR ENDOTHELIUM
Disclosed are methods, protocols, and compositions of matter related to utilization of chimeric antigen receptor (CAR) expressing cells for the targeting of...
2016/0228546 MODIFIED ANTIBODY COMPOSITIONS, METHODS OF MAKING AND USING THEREOF
The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified...
2016/0228545 Methods for treating and/or limiting development of diabetes in subjects with amyotrophic lateral sclerosis
Methods for treating and/or limiting development of diabetes in a subject with amyotrophic lateral sclerosis (ALS) by inhibiting IgG-mediated activation of...
2016/0228544 Single Walled Carbon Nanotube Polynucleotide Complexes and Methods Related Thereto
The present invention provides single-walled carbon nanotube formulations for the delivery of bioactive agents including large polynucleotides encoding...
2016/0228543 Continuous Cell Programming Devices
The present invention comprises compositions, methods, and devices for creating an infection-mimicking environment within a polymer scaffold to stimulate...
2016/0228542 METHOD OF INDUCING TOLERANCE TO AN ALLERGEN
The present invention relates generally to the field of allergies. More particularly, the present invention provides a method for treating an allergy in a...
2016/0228541 PAPAYA MOSAIC VIRUS AND VIRUS-LIKE PARTICLES IN CANCER THERAPY
Papaya mosaic virus and virus-like particles (VLPs) comprising ssRNA for use to inhibit cancer growth and metastasis. The PapMV and PapMV VLPs may be used...
2016/0228540 NASAL MUCOSAL VACCINE COMPOSITION
The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or...
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