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Patent # Description
2016/0228539 Toothpaste for Delivery of Allergens to Oral Mucosa
Pro-toothpaste compositions formulated to receive a volume of allergen solution to provide toothpastes that exhibit efficacy for oral mucosal immunotherapy...
2016/0228538 Porcine Pseudorabies Virus (PRV)-YF Strain and Its Application
The present invention relates to the technical field of porcine pseudorabies virus, and more particularly to a porcine pseudorabies virus (PRV)-YF strain, with...
2016/0228537 REVERSE VACCINATION THERAPY OF MULTIPLE SCLEROSIS
Disclosed are means of inducing antigen-specific tolerance through genetically modifying MSC to express antigens of interest in an inducible manner or...
2016/0228536 RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS (RSV) AND VACCINES
Described herein is a recombinant respiratory syncytial virus (RSV) having an attenuated phenotype. In one embodiment, recombinant RSV includes an M2-2 protein...
2016/0228535 INFLUENZA VIRUS MUTANTS AND USES THEREFOR
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein...
2016/0228534 INFLUENZA VIRUS MUTANTS AND USES THEREFOR
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein...
2016/0228533 Use of EGFR Pathway Inhibitors to Increase Immune Responses to Antigens
This disclosure relates to using EGFR pathway inhibitors in combination with compositions comprising an antigen to increase, elicit, or improve an antigen or...
2016/0228532 METHOD OF OBTAINING THERMOSTABLE DRIED VACCINE FORMULATIONS
This present invention relates to compositions and methods for stabilizing a dried vaccine formulations. In particular, the invention provides a method for...
2016/0228531 TREATMENT OF HEPATITIS D VIRUS INFECTIONS BY REDIRECTION OF T CELLS
Several approaches to treat, inhibit, or prevent HDV infections by redirecting T cells to HDV and HDV infected cells are described. In several alternatives, a...
2016/0228530 COMBINATION THERAPY FOR USE IN CANCER THERAPY
The present invention provides methods of treating anal or vaginal tumors and cancers, comprising the step of administering to a subject a combination therapy...
2016/0228529 MENINGOCOCCAL VACCINE FORMULATIONS
A dual formulation for vaccines against Neisseria meningitidis serogroup B (`Men-B`) comprises (i) an oil-in-water emulsion adjuvant and (ii) a Men-B...
2016/0228528 A SINGLE OR MULTISTAGE MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS SUBUNIT VACCINE
The present invention provides one or more immunogenic polypeptides for use in a preventive or therapeutic vaccine against latent or active infection in a...
2016/0228527 YERSINIA SPP. POLYPEPTIDES AND METHODS OF USE
The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one...
2016/0228526 LPS VACCINE
A vaccine composition for birds comprising as an active ingredient a structure containing O-antigen derived from Gram-negative bacteria, provided that said...
2016/0228525 MALARIA VACCINE
Embodiments are directed to malaria vaccines comprising a bacteriophage VLP displaying a heterologous peptide identified by affinity selection as an...
2016/0228524 AUTOLOGOUS CANCER CELL VACCINE
An autologous cancer cell vaccine comprises cancer cells that express both MHCI and MHCII on their cell surface. The MHCI presents a cancer antigen and the...
2016/0228523 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER USING BACTERIA
Provided herein are compositions comprising substantially non-viable Gram-negative bacterial organisms that have a substantial reduction in endotoxin activity...
2016/0228522 Oligomer-Specific Amyloid Beta Epitope and Antibodies
A novel constrained peptide epitope derived from A.beta., related antibody compositions and methods of use. An isolated antibody that specifically binds to a...
2016/0228521 MANAGING IMMUNE RESPONSES IN TRANSPLANTATION
The present invention provides, among other things, methods of treatment of donor and/or host subjects prior to, during, and/or after transplantation of donor...
2016/0228520 Compositions and Methods for Treating Granulomatosis with Polyangiitis
The present specification disclose methods and uses for the treatment of a vasculitic syndrome. The disclosed methods comprise administering a composition...
2016/0228519 THERAPEUTIC VEGETABLE SUBSTANCES
A pharmaceutical product containing papain, bromelain or mixtures thereof is intended for the treatment of several pathologies, such as Alzheimer's disease and...
2016/0228518 Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract
The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said...
2016/0228517 High Osteocalcin Microcrystalline Hydroxyapatite For Calcium Supplement
An improved manufacturing process produces microcrystalline hydroxyapatrte with sustained gradual calcium release that avoids spiking in blood calcium levels....
2016/0228516 Long-Acting Formulations of Insulin
The application relates to an aqueous pharmaceutical formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine.
2016/0228515 METHODS TO TREAT DYSREGULATED BLOOD GLUCOSE DISORDERS
The invention provides methods and compositions for treating dysregulated blood glucose disorders.
2016/0228514 USES OF MODIFIED MULLERIAN INHIBITING SUBSTANCE (MIS) PROTEINS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
The present invention relates to methods to treat a neurodegenerative disease or disorder, e.g., a motor neuron disease in a subject, whereby the subject is...
2016/0228513 TREATMENT OF MELANOMA WITH INTERFERON-BETA AND RAS-RAF-MEK-ERK INHIBITOR COMBINATION THERAPY
This description relates to the use of a polymer-conjugated interferon-beta as monotherapy or in combination with other cancer therapies.
2016/0228512 IFN-alpha/beta-Independent Mechanism of Antiviral Protection Through a Novel Ligand-receptor Pair: IFN-lambda...
A novel IFN-.alpha./.beta. independent ligand receptor system which upon engagement leads, among other things, to the establishment of an anti-viral state is...
2016/0228511 INHIBITION OF THE TUMORIGENIC POTENTIAL OF TUMOR STEM CELLS BY LIF AND BMPS
The present disclosure includes methods and compositions for the treatment or prevention of diseases and disorders characterized by excessive or misregulated...
2016/0228510 Method of Treating or Improving Neurological Function in a Human Subject
A method of treating or improving neurological function in a human subject includes identifying a human subject diagnosed with at least one of post-CNS trauma,...
2016/0228509 Diagnostic BioMarkers for Fibrotic Disorders
The present invention provides novel methods of inhibiting fibrosis, as well as methods of treating or inhibiting fibrotic disorders, using BMP9 and/or BMP10...
2016/0228508 CARTILAGE PRODUCT
The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5%...
2016/0228507 ISOLATED MUCINS AND DIFFERENT MICROORGANISMS, AND METHODS OF USE
A method of altering intercellular interactions between a combination of microorganisms includes contacting a combination of different species of ...
2016/0228506 Compositions and Formulations for Prevention and Reduction of Tumorigenesis, Cancer Cell Proliferation and...
Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant...
2016/0228505 USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES
The invention relates to the use of gelsolin to treat inflammatory diseases (e.g., rheumatoid arthritis) and to the use of gelsolin to diagnose, monitor, and...
2016/0228504 S100 BASED TREATMENT OF CARDIAC POWER FAlLURE
The present invention relates to S100 protein and nuclei acids encoding S100 protein for enhancing the cardiac power as well as vectors and pharmaceuticals...
2016/0228503 Compositions and Formulations for Prevention and Treatment of Diabetes and Obesity, and Methods of Production...
Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant...
2016/0228502 REGULATING CALCIUM IN EXCITABLE CELLS WITH A NOVEL PROTEIN
Embodiments of the disclosure concern methods and compositions related to the small Ankyrin 1 (sAnk1) protein and its role as a regulatory protein in at least...
2016/0228501 COMPOSITION FOR INHIBITING HUMAN CYTOMEGALOVIRUS REPLICATION
Provided is a novel pharmaceutical composition for inhibiting human cytomegalovirus (HCMV) replication by increasing the expression of a target gene of a notch...
2016/0228500 Immunogenic Polypeptides and Monoclonal Antibodies
Provided herein are compositions and methods for eliciting an immune response against Streptococcus pneumoniae. More particularly, the compositions and methods...
2016/0228499 THERAPY FOR SUBARACHNOID HEMORRHAGE AND ISCHEMIA
The application provides data from a clinical trial of a PSD-95 inhibitor in subjects undergoing endovascular repair of an aneurysm in or otherwise affecting...
2016/0228498 METHODS OF PREVENTING OR TREATING MUCOSITIS USING RLIP76
Provided are compositions and methods for preventing or treating damage to mucosal tissue, for example as a result of radiation and/or chemotherapy. The damage...
2016/0228497 NANOPARTICLES FOR DERMAL AND SYSTEMIC DELIVERY OF DRUGS
The present invention relates to a poly(lactic glycolic) acid (PLGA) nanoparticle associated with therapeutic agents for a variety of therapeutic applications.
2016/0228496 METHODS FOR TREATING HCV
The present invention features therapies for the treatment of HCV comprising direct-acting antiviral agents. Preferably, the treatment is administered to an...
2016/0228495 Targeting the EGFR-SGLT1 Interaction for Cancer Therapy
A compound can destabilize an epidermal growth factor receptor (EGFR) protein and a sodium/glucose co-transporter 1 (SGLT 1) protein. In one embodiment, the...
2016/0228494 MICROPARTICLES COMPRISING GNRH MADE BY PGSS
A pharmaceutical formulation comprising a solid matrix of one or more biodegradable polymers, the solid matrix including a pharmaceutically active substance or...
2016/0228493 AMINOSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS
The present invention relates to compounds of the formula (I) and in particular medicaments comprising at least one compound of the formula (I) for use in the...
2016/0228492 INHIBITORS OF VALOSIN-CONTAINING PROTEIN AND METHODS OF USE
A method of inhibiting aberrant valosin-containing protein (VCP) accumulation in the mitochondria of a nerve cell includes administering to the nerve cell a...
2016/0228491 THERAPEUTIC COMPOSITIONS INCLUDING PHENAZINE-3-ONE AND PHENOTHIAZINE-3-ONE DERIVATIVES AND USES THEREOF
Disclosed herein are methods and compositions for the treatment and/or prevention of diseases or conditions comprising administration of phenazine-3-one and/or...
2016/0228490 METHODS AND COMPOSITIONS FOR TREATING MUCUSAL TISSUE DISORDERS
The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases...
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