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Patent # Description
2016/0235849 High Concentration Antibody Formulations
Discloses herein are high concentration antibody formulations comprising an anti-sclerostin immunoglobulin and an acetate salt and/or an acetate buffer and...
2016/0235848 CATIONIC ANTISEPTIC COMPOSITIONS AND METHODS OF USE
Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic...
2016/0235847 NAIL FUNGUS TREATMENT AND COMPOSITION
A method for delivering an antifungal agent to a nail surface or a surface of a body excluding an oral cavity includes the step of adding the antifungal agent...
2016/0235846 Control of Blood Vessel Physiology To Treat Skin Disorders
In a method for treating an affected skin region of a patient having a skin disorder, a vasodilation composition is applied to an affected skin region of a...
2016/0235845 Buffer Formulations for Enhanced Antibody Stability
The invention provides buffered formulations of adalimumab. The formulations comprise a buffer comprising an acetate salt, mannitol, glacial acetic acid,...
2016/0235844 METHODS OF TREATING NEUROENDOCRINE TUMORS USING FRIZZLED-BINDING AGENTS
Novel methods of treating neuroendocrine tumors are provided. In one embodiment, the method comprises administering to a subject in need thereof a...
2016/0235843 METHODS FOR INCREASING NEURONAL SURVIVAL
Described are methods of treating a subject after acute trauma to the head, viral encephalitis, or other causes of acute neurodegeneration, and/or after acute...
2016/0235842 MEDICAL USES OF CD38 AGONISTS
Methods and compositions relating to medical (e.g., therapeutic) use of CD38 agonists are provided. In some embodiments, the present invention provides methods...
2016/0235841 FGF MODULATION OF IN VIVO ANTIBODY PRODUCTION AND HUMORAL IMMUNITY
The invention provides methods for increasing or decreasing antibody production in vivo by inhibiting or promoting the activity of fibroblast growth factor-2...
2016/0235840 Compositions, Comprising Improved Il-12 Genetic Constructs And Vaccines, Immunotherapeutics And Methods Of...
Nucleic acid molecules and compositions comprising: a nucleic acid sequence that encodes IL-12 p35 subunit or a functional fragment thereof and/or a nucleic...
2016/0235839 CALCIUM FLUORIDE COMPOSITIONS
Compositions comprising calcium fluoride composites comprising Ca, F, and an organic molecule are provided, as are methods for their use.
2016/0235838 Vaccines With Interleukin-33 As An Adjuvant
Disclosed herein is a vaccine comprising an antigen and IL-33. Also disclosed herein is a method for increasing an immune response in a subject in need...
2016/0235837 THERAPIES, VACCINES, AND PREDICTIVE METHODS FOR MIDDLE EAST RESPIRATORY SYNDROME VIRUS (MERS CoV)
The present invention provides an isolated or synthesized protein fragment or peptide comprising at least one peptide sequence that is at least 50% homologous...
2016/0235836 MOSAIC HIV ENVELOPE IMMUNOGENIC POLYPEPTIDES
Disclosed herein are mosaic HIV envelope (Env) polypeptides that can elicit an immune response to HIV (such as cytotoxic T cell (CTL), helper T cell, and/or...
2016/0235835 INFLUENZA VACCINES WITH REDUCED AMOUNTS OF SQUALENE
Influenza vaccines include hemagglutinin from at least one influenza A virus strain and at least one influenza B virus strain. They also include an...
2016/0235834 LIVE ATTENUATED VACCINES
The present invention refers to a method for the production of live attenuated bacterial strains, suitable as vaccine candidates, comprising the steps of: A....
2016/0235833 Chimeric Factor H Binding Proteins (fHBP) and Methods of Use
Chimeric fHbps that can elicit antibodies that are bactericidal for different fHbp variant strains of N. meningitidis, and methods of use, are provided.
2016/0235832 Compositions and the Use of Fibrinogen Binding Motif Presence in EFB and COA for Vaccine Against Staphylococcus...
The present disclosure provides methods and composition including vaccines, monoclonal antibodies, polyclonal antibodies, chimeric molecule of an extracellular...
2016/0235831 Process For Stabilizing An Adjuvant Containing Vaccine Composition
The present invention relates to a process for stabilizing an adjuvant containing vaccine composition, an adjuvanted vaccine composition in dry form and in...
2016/0235830 CHIMERIC OSPA GENES, PROTEINS AND METHODS OF USE THEREOF
The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the...
2016/0235829 VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS
The present disclosure provides (a) vectors comprising a multi-antigen construct encoding two, three, or more immunogenic PAA polypeptides; (b) compositions...
2016/0235828 NOVEL PEPTIDE HAVING 4 LINKED CTL EPITOPES
This invention provides a cancer antigen peptide that can be administered to a wide range of cancer patients in the form of a peptide vaccine for cancer...
2016/0235827 PLACENTAL COMPOSITIONS FOR STIMULATION OF IMMUNITY TO PD-L1
Disclosed is the new, useful, and unexpected finding that immunization to placental endothelial cells stimulated with interferon gamma result in antibodies to...
2016/0235826 HISTONE DEACETYLASE COMPOSITIONS AND USES THEREOF
The present invention is based, at least in part, on the discovery that fragments of the histone deacetylase 4 (HDAC4) gene lacking the enzymatic domain...
2016/0235825 Formulation for Oral Administration of Proteins
Pharmaceutical formulations of orally administered proteins can be stabilized from oxidative degradation and inactivation in the stomach and GI tract by the...
2016/0235824 Compositions and Methods for Increasing the Half-Life of Factor XA
Compositions and methods for the modulation of hemostasis are disclosed.
2016/0235823 METHODS AND COMPOSITIONS FOR REDUCING THE ENVIRONMENTAL IMPACT OF ANIMAL WASTE
Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an...
2016/0235822 DIETARY SUPPLEMENTS AND FORMULATIONS
Provided are dietary supplements, formulations, kits and methods for administration to an individual with type II diabetes or at risk of developing type II...
2016/0235821 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER, CONTAINING CYB5R3 GENE OR PROTEIN AS ACTIVE...
The present invention relates to a pharmaceutical composition for treating cancer, containing cytochrome b5 reductase 3 (CYB5R3) protein as an active...
2016/0235820 METHOD OF INJECTING A KERATIN-BASED MATERIAL INTO A TARGET REGION OF THE HEART
A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes...
2016/0235819 METHODS OF INDUCING MELANOGENESIS IN A SUBJECT
Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH...
2016/0235818 Treatment of Pediatric Type 2 Diabetes Mellitus Patients
The present invention refers to lixisenatide for use in pediatrics.
2016/0235817 ACTH FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
Provided herein are methods of treatment of Amyotrophic Lateral Sclerosis comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog,...
2016/0235816 METHODS FOR THE TREATMENT OF INFLAMMATORY JOINT DISEASE
This invention provides compositions and methods for preventing inflammatory diseases of the joints, including rheumatoid and osteoarthritis, tendonitis,...
2016/0235815 COMPOSITION COMPRISING A MIXTURE OF CD95-FC ISOFORMS
The present invention relates to a composition comprising a mixture of fusion protein isoforms, each fusion protein comprising an extracellular CD95 domain or...
2016/0235814 SOLUBLE FC GAMMA RECEPTOR FOR TREATMENT OF AUTOIMMUNE BULLOUS DISEASES
The invention generally relates to the field of biotechnology and medicine. It provides an agent, a pharmaceutical composition and a kit for treatment of...
2016/0235813 ANTI-INFLAMMATORY PROTEINS AND METHODS OF USE
A method and composition for reducing or alleviating inflammation in a subject is provided, including administering to the subject a therapeutically effective...
2016/0235812 METHODS FOR TREATING FIBROTIC CANCERS
In part, the disclosure relates to methods of treating fibrotic cancers by administering one or more Serum Amyloid Protein (SAP) agonists. In certain aspects,...
2016/0235811 COMPOUNDS AND METHODS FOR THE TREATMENT OF VASCULAR DISEASE
The present invention relates to a method for the treatment of vascular dysfunction, reducing ischemic pain and/or treatment of a vascular disease comprising...
2016/0235810 METHODS OF TREATING DIABETES AND RELATED DISORDERS
The invention relates to methods of treating metabolic conditions, including type 2 diabetes mellitus, by administering prolactin-inducible protein (PIP) or...
2016/0235809 Compositions for Treating Dry Eye Disease
The present invention provides a pharmaceutical composition, and methods of use thereof, for treating ocular boundary deficiency, symptoms associated...
2016/0235808 Treatment of Hepatitis C Virus Infection with Alisporivir
The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus infection.
2016/0235807 AGONISTS OF GUANYLATE CYCLASE USEFUL FOR DOWNREGULATION OF PRO-INFLAMMATORY CYTOKINES
This invention provides a method to prevent, control, and/or treat an inflammatory disease or disorder by administering at least one agonist of guanalyte...
2016/0235806 Novel Peptide Compound for Inhibiting Restenosis and Promoting Re-Endothelialization and Method for Preparing...
Provided are a peptide compound prepared by additional synthesis in a drug having an effect of inhibiting restenosis, a composition for inhibiting restenosis...
2016/0235805 HCV PROTEASE INHIBITORS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
2016/0235804 METHODS OF PRODUCING ANAMORELIN HYDROCHLORIDE HAVING CONTROLLED CHLORIDE CONTENT
The present invention relates to particulate forms of anamorelin monohydrochloride or a composition comprising anamorelin monohydrochloride having controlled...
2016/0235803 TURMERIC EXTRACT CONTAINING SOFT PASTILLES
The present disclosure provides a soft pastille containing turmeric extract as an active ingredient. The pastille is prepared using at least one gelling agent...
2016/0235802 Traditional Chinese Medicine capable of triggering Lung Adenocarcinoma cell Autophagy, and composition and...
A Chinese medicine capable of triggering lung adenocarcinoma cell autophagy mainly uses a polygala tenuifolia willd herb with a quantity depending on a...
2016/0235801 PHYTOCHEMICAL ENHANCED WATER
A method and formulation for fluids, such as drinking water, containing plant phytochemicals are disclosed. Some plants can survive in water without a root...
2016/0235800 Compositions for Reducing Environmental Sensitivity and Regulating Immune Function
The present invention is directed to compositions for improving immune function and sensitivities to the natural and manmade environment that include...
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