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SUBGENOMIC REPLICONS OF THE FLAVIVIRUS DENGUE
The present invention discloses the construction of dengue virus subgenomic replicons containing large deletions in the structural region (C-preM-E) of the...
Recombinant Protein Bodies as Immunogen-Specific Adjuvants
An immunogen-specific is adjuvant for a vaccine or inoculum is disclosed. The adjuvant is comprised of particulate recombinant protein body-like assemblies...
Attenuated Mannheimia haemolytica Strains
The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said...
VACCINE COMPRISING PROTEIN NMB0964 FROM NEISSERIA MENINGITIDIS
The present invention relates to immunogenic compositions comprising neisserial blebs with upregulated levels of the NMB0964 antigens such that bactericidal...
METHODS AND COMPOSITIONS BASED ON SHIGA TOXIN TYPE 2 PROTEIN
The invention is based on the discovery of the epitope in the Stx2 protein for the 11 E1O antibody. The invention features compositions containing non-full...
TUMOR ANTIGEN BASED ON PRODUCTS OF THE TUMOR SUPPRESSOR GENE WT1
A tumor antigen that comprises, as an active ingredient, a product of the Wilms' tumor suppressor gene WT1 or a peptide composed of 7-30 contiguous amino acids...
FUSION MOLECULE BASED ON NOVEL TAA VARIANT
This invention provides novel carbonic anhydrase (CAIX) nucleic acid and peptide sequences, as well as related methods and compositions, including anti-cancer...
AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE
There is provided a method for treating or reducing the effects of fructose intolerance and health problems associated with excessive fructose intake by...
Factor IX Polypeptides and Methods of Use Thereof
The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; chimeric and...
RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF
The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins....
CANDIDATES AGAINST INFECTION
The present invention relates to the use of plasminogen/plasmin and its derivatives as agents for enhancing host defense against infection or other infectious...
TREATMENT OF POMPE'S DISEASE
The invention provides methods of treating Pompe's disease using human acid alpha glucosidase. A preferred treatment regime comprises administering greater...
COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF METABOLIC
STEATOSIS AND STEATOHEPATITIS
The invention relates to an orally administered drug or medical nutrition composition for use in the prevention or treatment of metabolic steatosis and...
METHODS AND COMPOSITIONS FOR INCREASING HEPCIDIN EXPESSION USING MODIFIED
IRON BINDING/RELEASING TRANSFERRIN
Provided are methods for increasing hepcidin expression, treating a disorder associated with iron overload, decreasing non-transferrin bound iron (NTBI),...
MEDICAMENT FOR TREATING OLFACTION DISORDER
The object of the present invention is to provide an olfactory disturbance therapeutic agent that is effective in repairing or regenerating olfactory...
LIQUID INSULIN FORMULATIONS AND METHODS RELATING THERETO
Liquid formulations of insulin that contain physically and chemically stable insulin but do not contain preservatives or stabilizers are provided. The...
Pharmaceutical Composition for Preventing or Treating Osteoporosis Which
Comprises Neuropeptide Y as Active...
The present invention relates to a pharmaceutical composition for preventing or treating osteoporosis which comprises neuropeptide Y as an active ingredient....
USE OF GHRELIN OR FUNCTIONAL GHRELIN RECEPTOR AGONISTS TO PREVENT AND
TREAT STRESS-SENSITIVE PSYCHIATRIC ILLNESS
The invention relates to methods of treating stress-sensitive psychiatric diseases arising from trauma in a subject by enhancing ghrelin signaling in the BLA...
Methods of Using Interleukin-10 for Treating Diseases and Disorders
Methods of treating subjects having diseases, disorders, or conditions, including cancer and immune- and inflammatory-related disorders, via the administration...
COMPOSITIONS INCLUDING IL-18 AND IL-22 AND THEIR USE IN ANTI-VIRAL
The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some...
PUMA PROTEIN EXPRESSION VECTOR AND USE THEREOF IN GENE THERAPY
The present invention relates to a viral vector for expression of the cell death-inducing PUMA protein, for use in gene therapy, for example for the treatment...
METHODS AND COMPOSITIONS FOR THE REDUCTION OF NEUTROPHIL INFLUX AND THE
TREATMENT OF BRONCHOPULMONARY...
The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in...
ANTIBODY DEPENDENT EXOSOME THERAPY
Described herein are methods, pharmaceutical compositions and kits for treating cancer in a subject in need thereof by administering an effective amount of a...
Compositions for the Treatment of Cancer, and Methods for Testing and
Using the Same
The invention relates to pharmaceutical compositions comprising leukotoxin, including methods to treat lymphoma, and methods to diagnose lymphoma. The lymphoma...
DOSES AND METHODS FOR ADMINISTERING TELAVANCIN
Doses and methods for administering telavancin or a pharmaceutically-acceptable salt thereof to a human patient having an infection caused by Staphylococcus...
MUCOADHESIVE NANOPARTICLE COMPOSITION COMPRISING IMMUNOSUPPRESANT AND
METHODS OF USE THEREOF
Disclosed is a mucoadhesive nanoparticle delivery system for delivering an immunosuppressant, such as cyclosporine A, to a mucosal site for treatment of a...
AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL
DISORDERS, INFLAMMATION, CANCER AND...
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders,...
METHODS OF TREATING ACUTE MYELOID LEUKEMIA WITH A FLT3 MUTATION
There is provided a method of treating acute myeloid leukemia (AML). The method includes the step of administering to a patient having AML with a FMS-like...
OBTAINING A JUICE OF FRESH PLANTS BY THERMOMECHANICAL TREATMENT AND
COSMETIC AND THERAPEUTIC USE THEREOF
The present invention relates to a process for obtaining a juice of fresh plants, characterized in that said fresh plants, with the exclusion of the seeds...
Bioactive-rich concentrates and nutritive and therapeutic products
This invention relates generally to the field of compositions for use as nutraceuticals, food additives or adjuncts to conventional drug therapies. In...
METHODS FOR NATURAL RELUBRICATION FOR VAGINAL ATROPHY
The invention provides a new option for women suffering from vaginal atrophy caused by the declining production of estrogen. It provides methods using coconut oil...
EXTRACTION OF B-VITAMINS FROM PLANT MATTER
A process for the extraction of the B group of vitamins from a first plant matter is disclosed wherein, prior to the said extraction operation, the first plant...
USE OF CISSAMPELOS PAREIRA EXTRACTS FOR TREATING DENGUE
The present invention relates to an extract of Cissampelos pareira, its pharmaceutical compositions, and its therapeutic use in the prevention and treatment of...
COMPOSITION FOR PREVENTING OR TREATING STROKE OR NEURODEGENERATIVE
DISEASE, COMPRISING EXTRACT COMPLEX OF...
A composition, a health functional food or a treatment method of the present invention has a remarkable cranial nerve cell protection effect and simultaneously...
ANTICANCER COMPOSITION CONTAINING MIXED HERBAL MEDICINE EXTRACT AS ACTIVE
An embodiments of the invention relates to a composition containing, as an active ingredient, a mixed extract of Astragalus membranaceus, Angelica gigas, and...
USE OF FENUGREEK EXTRACT TO ENHANCE PSYCHOLOGICAL, SOMATIC, AND SEXUAL
CONDITIONS IN AGING MALES
Novel methods of improving or enhancing psychological, somatic, and sexual conditions in an aging male human subject, by administering fenugreek or fenugreek...
Cannabis Conversion Process
A method for preparing an ingestible cannabis composition is provided. Also provided is the ingestible cannabis composition and a kit including the ingestible...
Method For Conducing Concentrated Cannabis Oil To Be Stable, Emulsifiable
And Flavorless For Use In Hot...
A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a...
EXTRACTS FROM PLANTS OF THE MORINGACEAE FAMILY AND METHODS OF MAKING
The present application is directed to materials and methods for producing extracts from a plant of the Moringaceae family having high concentrations of...
COMPOSITIONS AND METHODS COMPRISING A DEFINED MICROBIOME AND METHODS OF
The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention...
NOVEL BACTERIA ISOLATED FROM FRESH HONEY OR THE HONEY PRODUCING TRACT OF
The invention relates to new isolated Lactobacillus and Bifidobacterium strains which have been isolated from fresh honey having a water content above 18% by...
PROBIOTIC ENHANCEMENT OF STEROID AND IMMUNE SUPPRESSOR ACTIVITY IN MAMMALS
WITH CHRONIC DISEASES
This invention relates to use of probiotics, particularly P acidilactici and S boulardii, for use in conjunction with steroids and other immune suppressor...
Compositions and Methods for Inhibition of Pathogenic Bacterial Growth
Compositions for methods of preventing or reducing pathogenic bacterial growth, proliferation, and/or colonization are described containing one or more types...
THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS
The present invention provides improved methods and compositions based on microvesicles for the treatment of various diseases, disorders and conditions. In...
Compositions and Methods for Restoring or Rejuvenating Stem/Progenitor
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or...
DUAL VECTOR FOR INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS
The present invention provides an expression vector for preventing or inhibiting HIV entry, fusion or replication in mammalian cells. In particular, the...
ADOPTIVE CELL TRANSFER METHODS
Methods and compositions are presented for mobilizing hematopoietic stem cells (HSC) and for mobilizing T lymphocytes from the bone marrow and other...
COMPOSITIONS AND METHODS FOR MESENCHYMAL/STROMAL STEM CELL REJUVENATION
AND TISSUE REPAIR BY ENHANCED...
A major risk factor for ischemic heart disease is advanced age. In adult bone marrow and other tissues, the number and function of stem cells decline with...
MULTIPOTENT STEM CELLS AND USES THEREOF
The invention provides a quiescent stem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not express cell surface...
PROCESSING CELL THERAPY PRODUCTS
Systems, methods, and apparatus for processing cell therapy products are provided. A closed system can include a container, an expandable seal, a connector,...