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Patent # Description
2016/0243114 METHODS OF TREATING CANCER USING COMPOSITIONS COMPRISING PERILLYL ALCOHOL DERIVATIVE
A method for treating brain metastases of a cancer in a mammal includes administering to the mammal a therapeutically effective amount of a perillyl alcohol...
2016/0243113 Processes For Preparing Morphinan-6-One Products With Low Levels Of Alpha, Beta-Unsaturated Ketone Compounds
The present invention generally relates to processes for preparing highly pure morphinan-6-one products. The processes involve reducing the concentration of...
2016/0243112 TREATMENTS FOR ALZHEIMER'S RELATED DISEASES AND DISORDERS
The invention relates to a method for the treatment of neuropsychiatric behavioral symptoms in patients with Alzheimer's Disease wherein the symptoms are...
2016/0243111 Pegylated Opioids with Low Potential for Abuse
The invention provides opioid agonists covalently bound to a water-soluble oligomer having reduced potential for substance abuse and uses thereof. The...
2016/0243110 Encased Tamper Resistant Controlled Release Dosage Forms
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid...
2016/0243109 Encased Tamper Resistant Controlled Release Dosage Forms
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid...
2016/0243108 Encased Tamper Resistant Controlled Release Dosage Forms
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid...
2016/0243107 Opioid Antagonist Formulations
In certain embodiments, the present invention is directed to a solid controlled-release dosage form comprising a core comprising a core portion of an opioid...
2016/0243106 SLOW-RELEASE CONJUGATES OF SN-38
Conjugates of SN-38 that provide optimal drug release rates and minimize the formation of the corresponding glucuronate are described. The conjugates release...
2016/0243105 COMBINATION THERAPY
Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound...
2016/0243104 PHARMACEUTICAL TOPICAL COMPOSITIONS
The invention provides pharmaceutical stable semisolid topical compositions comprising between 0.2 to 5% of a des-fluoroquinolone compound, and a suitable...
2016/0243103 Treatment of BDNF-Related Disorders Using Laquinimod
This application provides for a method of increasing brain-derived neurotrophic factor (BDNF) serum level in a human subject comprising periodically...
2016/0243102 RHO KINASE INHIBITORS
Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of...
2016/0243101 APIXABAN FORMULATIONS
Compositions comprising crystalline apixaban particles having a D.sub.90 equal to or less than 89 .mu.m, and a pharmaceutically acceptable carrier, are...
2016/0243100 4-Methylsulfonyl-Substituted Piperidine Urea Compounds
The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM)...
2016/0243099 ASSAYS, METHODS AND MEANS
A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF...
2016/0243098 USE OF PRIDOPIDINE TO IMPROVE COGNITIVE FUNCTION AND FOR TREATING ALZHEIMER'S DISEASE
This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or...
2016/0243097 METHODS OF TREATING POXVIRAL INFECTIONS
Provided are methods of treating a disease or condition caused by or associated with a virus belonging to the Poxviridae family using iminosugars, such as DNJ...
2016/0243096 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS
Provided are novel iminosugars and methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the...
2016/0243095 COMPOSITIONS FOR THE TREATMENT OF CNS-RELATED CONDITIONS
The invention provides methods for treating CNS-related conditions with amantadine and donepezil, in which the amantadine is in an extended release form,...
2016/0243094 COMPOSITIONS FOR THE TREATMENT OF CNS-RELATED CONDITIONS
The invention provides methods for treating CNS-related conditions with amantadine and donepezil, in which the amantadine is in an extended release form,...
2016/0243093 COMPOSITIONS FOR THE TREATMENT OF CNS-RELATED CONDITIONS
The invention provides methods for treating CNS-related conditions with amantadine and donepezil, in which the amantadine is in an extended release form,...
2016/0243092 KINASE MODULATION, AND INDICATIONS THEREFOR
The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated...
2016/0243091 Tacrolimus For Improved Treatment Of Transplant Patients
An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive...
2016/0243090 MODIFIED RELEASE COMPOSITIONS COMPRISING TACROLIMUS
A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro...
2016/0243089 FORAZOLINES, COMPOSITIONS THEREOF AND USES THEREOF
An isolated compound of Formula I and salts thereof are provided: ##STR00001## wherein X is Cl or Br. A compound isolated from Actinomadura and having a chemical...
2016/0243088 ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE
Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
2016/0243087 CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF NITAZOXANIDE
Solid dosage formulations of nitazoxanide or a nitazoxanide analogue are provided that comprise a controlled release portion and an immediate release portion....
2016/0243086 AGENT FOR REDUCING VISCERAL FAT WEIGHT
An FGF21 production promoting agent containing, as an active ingredient, a compound represented by the following formula (1): ##STR00001## wherein each of...
2016/0243085 SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS
Substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein...
2016/0243084 USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES
The aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile increases testosterone levels and treats hypogonadism and related...
2016/0243083 TREATMENT USING DANTROLENE
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for...
2016/0243082 4-Methylpyrazole Formulations for Inhibiting Ethanol Intolerance
Provided herein are methods, compositions and formulations to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with...
2016/0243081 USE OF A PYRAZOLE DERIVATIVE IN THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methyl- benzamide or a pharmaceutically acceptable derivative thereof in the manufacture of a...
2016/0243080 FORMULATIONS OF ANGIOTENSIN RECEPTOR BLOCKERS
Provided herein are pharmaceutical compositions for the treatment of wounds, including chronic wounds and diabetic ulcers. The pharmaceutical compositions,...
2016/0243079 KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN
Compositions comprising ketorolac tromethamine at a therapeutically effective concentration of less than 0.5% are disclosed herein. Methods of treating or...
2016/0243078 KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN
The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous...
2016/0243077 COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutically active agents previously limited by...
2016/0243076 Methods and Compositions for Improving Cognitive Function
This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning,...
2016/0243075 TETRAHYDROCANNABIVARIN (THC) FOR USE IN THE PROTECTION OF PANCREATIC ISLET CELLS
The present invention relates to the phytocannabinoid tetrahydrocannabivarin (THCV) for use in the protection of pancreatic islet cells. Preferably the...
2016/0243074 SPARC AND METHODS OF USE THEREOF
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor...
2016/0243073 Treatment of Obesity Using Non-Daily Administration of 6-O-(4-Dimethylaminoethoxy) Cinnamoyl Fumagillol
The invention generally relates to methods of treating an overweight or obese subject, and treating overweight- or obesity-related conditions using non-daily...
2016/0243072 Controlled Release Dosage Form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in...
2016/0243071 SOLID COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and...
2016/0243070 OXYBUTYNIN TRANSDERMAL THERAPEUTIC SYSTEM COMBINATION
There is described a pharmaceutical combination comprising oxybutynin or a pharmaceutically acceptable addition salt thereof, in a transdermal therapeutic...
2016/0243069 Compositions and Methods For Using Esters Of Meroterpenes and of Other Resveratrol Analogues
The invention includes compositions and methods of using meroterpene esters for effectively modulating skin cell function and remediating undesirable skin...
2016/0243068 OMEGA-3 COMPOSITIONS, DOSAGE FORMS, AND METHODS OF USE
Omega-3 compositions, dosage forms, and methods of use are disclosed herein. The omega-3 compositions and dosage forms disclosed herein may comprise DHA and...
2016/0243067 Controlled Release Dosage Form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in...
2016/0243066 ANTHRAQUINONE COMPOUNDS AND THEIR USES
The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a...
2016/0243065 TOPICAL DAPSONE AND DAPSONE/ADAPLENE COMPOSITIONS AND METHODS FOR USE THEREOF
Dapsone and dapsone/adapalene compositions can be useful for treating a variety of dermatological conditions. The compositions of this disclosure include...
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