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Patent # Description
2016/0250356 TARGETED CONTRAST AGENTS AND METHODS FOR TARGETING CONTRAST AGENTS
A contrast agent having a contrast protein have contrast properties and at least one targeting moiety, wherein the at least one targeting moiety is operatively...
2016/0250355 METHODS AND DIAGNOSTIC KIT FOR VISUALIZING BODY TISSUES AND COMPONENTS THEREIN
The present disclosure is directed to methods and a diagnostic kit for producing pericyte information from a subject for identifying and/or treating a subject...
2016/0250354 METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS
A lipid particle can include a cationic lipid. The cationic lipid can include one or more hydrophobic tails, which can include one or more sites of...
2016/0250353 CREPED PREBIOTIC TISSUE
The invention relates to creped prebiotic tissue products. The tissue products comprise prebiotics in sufficiently high amounts to have a prebiotic effect in...
2016/0250352 SHIELDED BIOLOGIC THERAPEUTIC
The present invention provides a shielded biologic therapeutic comprising a biologic therapeutic which is covalently and cleavably bound to one or more...
2016/0250351 Treating Lymphomas
This document provides methods and materials related to treating lymphomas. For example, methods and materials relating to the use of a composition containing...
2016/0250350 DELIVERY SYSTEM FOR CYTOTOXIC DRUGS BY BISPECIFIC ANTIBODY PRETARGETING
The present invention relates to methods and compositions for pretargeting delivery of therapeutic agents. In preferred embodiments, the pretargeting method...
2016/0250349 A NOVEL STABLE FORMULATION
The present invention relates to a stable formulation particularly suitable for the anti-mesothelin immunoconjugate MF-T-SPDB-DM4. The described stable aqueous...
2016/0250348 Anti-DLL3 antibody drug conjugates
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
2016/0250347 MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF
Glycoproteins comprising a glycan of the formula (102) are disclosed; wherein b is 0 or 1; the GlcNAc residue optionally fucosylated; and Su(A).sub.x is a...
2016/0250346 PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
Conjugates of specific PBD dimers with an antibody that binds to CD22, the antibody comprising a VH domain having the sequence according to SEQ ID NO. 1.
2016/0250345 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
A compound which is selected from A: A O OO O O O I O NH O O O O O O O O N H N H N H OO OH H O N N OO H N N B: 5 B O OO O O O Br O NH O O O O O O O O N H N H N...
2016/0250344 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
A compound which is selected from A: and salts and solvates thereof. ##STR00001##
2016/0250343 COMBINATION THERAPY FOR TREATMENT OF CANCER
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising...
2016/0250342 Hydrazinyl-Indole Compounds and Methods for Producing a Conjugate
The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The...
2016/0250341 DESIGNED REPEAT PROTEINS BINDING TO SERUM ALBUMIN
New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins,...
2016/0250340 POLYMER CONJUGATES OF INTERFERON BETA-1a AND USES
An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and...
2016/0250339 Pegylated Artesunate Derivative, Pharmaceutical Composition and Use Thereof
A pegylated artesunate derivative, a pharmaceutical composition and uses thereof, the pegylated artesunate derivative is represented by the general formula...
2016/0250338 MICELLIC ASSEMBLIES
Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive...
2016/0250337 BIOMEDICAL IMAGING AND THERAPY USING RED BLOOD CELLS
Certain embodiments of the present invention provide methods, of treating a skin abnormality in a mammalian subject, that involve introducing, into a...
2016/0250336 CHINESE HERB MEDICINE COMPOSITION IN THE FORM OF JELLY
A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected...
2016/0250335 FAST DISINTEGRATING COMPOSITIONS AND TABLETS THEREOF
Compositions useful for making dosage forms capable of dissolving or disintegrating in less than 10 seconds without the need for conventional disintegrants and...
2016/0250334 Acetylcysteine Compositions and Methods of use Thereof
A pharmaceutical composition and method for providing a reduction in side effects for human patients in need of therapy comprising the administration of a...
2016/0250333 SUBCUTANEOUS INJECTION PREPARATION FOR INDUCING BOVINE SUPEROVULATION
The present invention provides a subcutaneous injection product for cattle for inducing superovulation characterized by comprising aluminum hydroxide gel and...
2016/0250332 UPCONVERTING NANOPARTICLES
Provided herein are lanthanide-containing upconverting nanoparticles, methods of their preparation, compositions, and methods of using the same. The polymers...
2016/0250331 Biodegradable Magnetic Nanoparticles and Related Methods
The design of biodegradable magnetic nanoparticles for use in in-vivo biomedical applications. The particles can include Fe in combination with one or more of...
2016/0250330 SCINTILLATOR NANOCRYSTAL-CONTAINING COMPOSITIONS AND METHODS FOR THEIR USE
There are provided, inter alia, compositions including a scintillator nanocrystal linked to a chemical agent moiety through a scintillator-activated...
2016/0250329 ANTIBODY COMPOSITION
The invention provides a method for stabilizing antibody at high concentrations using albumin; use of albumin to stabilize high concentration antibody...
2016/0250328 COMBINATION THERAPY FOR TREATING HER2-POSITIVE CANCERS
Methods for treating cancer patients with HER2-positive tumors are disclosed. The methods comprise administering to a patient a therapeutically effective...
2016/0250327 METHODS AND COMPOSITIONS TO REDUCE LIVER DAMAGE ASSOCIATED WITH CONDITIONS OR THERAPIES THAT AFFECT THE IMMUNE...
One side-effect arising from the use of antibodies against TNF receptor family members as therapeutics can be liver damage which precludes the completion of...
2016/0250326 Conjugates of GM-CSF and IL-7, and Compositions Thereof
In certain embodiments, this disclosure relates to conjugates comprising GM-CSF and IL-7 and uses related thereto, e.g., enhancing the adaptive immune system....
2016/0250325 ADJUVANT COMPOUND
The invention is directed to a compound according to the formula [1] ##STR00001## wherein R.sup.1 and R.sup.2 are branched or straight groups having up to 17...
2016/0250324 VACCINE COMPOSITION COMPRISING AN IMMUNOGENIC PROTEIN AND COMBINATION ADJUVANTS FOR USE IN ELICITING...
Vaccine compositions for use in inducing enhanced antigen-specific T cell-mediated immune responses in a subject in need thereof are disclosed. The composition...
2016/0250323 Particles Comprising a Shell with RNA
The present invention relates to RNA decorated particles such as RNA decorated lipid particles, preferably to RNA decorated liposomes. Further, the present...
2016/0250322 VECTOR CO-EXPRESSING VACCINE AND COSTIMULATORY MOLECULES
Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among...
2016/0250321 NUCLEIC ACIDS COMPRISING FORMULA (NuGlXmGnNv)a AND DERIVATIVES THEREOF AS IMMUNOSTIMULATING AGENT/ADJUVANT
The present invention relates to nucleic acids of the general formula (I): (N.sub.uG.sub.lX.sub.mG.sub.nN.sub.v).sub.a and derivatives thereof as an...
2016/0250320 IMMUNOREGULATORY PEPTIDES AND METHODS OF USE
Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are...
2016/0250319 THERMOSTABLE RESPIRATORY SYNCTIAL VIRUS (RSV) VACCINE COMPOSITIONS
Methods for improving the drying yield and stability of RSV vaccines comprising a highly thermolabile enveloped live virus and/or one or more RSV protein...
2016/0250318 BIVALENT SWINE INFLUENZA VIRUS VACCINE
The present invention relates to an immunogenic composition comprising: a) a modified live H3 virus of swine influenza, and b) a modified live H1 virus of...
2016/0250317 SCHMALLENBERG VIRUS (SBV) VACCINE, METHODS OF PRODUCTION, AND USES THEREOF
The present invention relates to the field of vaccines and medicaments for the prophylaxis and treatment of infectious diseases in ruminants. In particular, it...
2016/0250316 IMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR A FRAGMENT THEREOF
The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide,...
2016/0250315 HUMAN PAPILLOMA VIRUS THERAPEUTIC VACCINE
Peptides and compositions for a therapeutic vaccine to treat persons infected with human papilloma virus are presented. Methods of using the compositions and...
2016/0250314 COMPOSITIONS AND METHODS FOR DETECTING, TREATING, AND PROTECTING AGAINST FUSOBACTERIUM INFECTION
The present invention relates to protecting against, treating, and detecting Fusobacteria infections. Compositions and methods derived from nucleic acid and...
2016/0250313 FUSION PROTEINS AND COMBINATION VACCINES COMPRISING HAEMOPHILUS INFLUENZAE PROTEIN E AND PILIN A
The present invention relates to compositions comprising Haemophilus influenzae Protein E and Pilin A. More particularly, the present application relates to...
2016/0250312 MALARIA VACCINATION
The invention relates to an antigenic composition or vaccine comprising a viral vector, the viral vector comprising nucleic acid encoding Plasmodium protein...
2016/0250311 DNA VACCINE FOR USE IN PANCREATIC CANCER PATIENTS
The present invention relates to an attenuated mutant strain of Salmonella comprising a recombinant DNA molecule encoding a VEGF receptor protein. In...
2016/0250310 GALECTIN-3 AS IMMUNOLOGICAL TARGET
AnnexinA2 (ANXA2), a member of the Annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by...
2016/0250309 COMPOSITIONS AND METHODS FOR CANCER TREATMENT
Compositions and methods for delivering tumor associated antigens and immune modulatory molecules to result in a therapeutic effect are disclosed. The...
2016/0250308 SEMI-ALLOGENIC ANTI-TUMOUR VACCINE WITH HLA HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding...
2016/0250307 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
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