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Patent # Description
2016/0250256 TUMORICIDAL AND ANTIMICROBIAL COMPOSITIONS AND METHODS
Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and...
2016/0250255 METHODS FOR INDUCTION OF ANTIGEN-SPECIFIC REGULATORY T CELLS
The present invention relates to methods of obtaining antigen-specific regulatory cells in vitro or in vivo. The regulatory cells are obtainable by inducing...
2016/0250254 METHODS OF REDUCING DOSES OF ERYTHROPOIETIN STIMULATING AGENTS IN HYPORESPONSIVE PATIENTS
The invention provides for methods of treating a dialysis patient that is hyporesponsive to erythropoietin stimulating agents (ESA) comprising administering...
2016/0250253 STRONTIUM-CONTAINING COMPLEXES FOR TREATING GASTROESOPHAGEAL REFLUX AND BARRETT'S ESOPHAGUS
Therapeutically-active compositions for treating pain, irritation, and inflammation associated with gastroesophageal reflux and Barrett's esophagus that...
2016/0250252 BIOACTIVE GAS-ENCAPSULATED ECHOGENIC LIPOSOMES AND METHODS FOR TREATING CARDIOVASCULAR DISEASE
Echogenic liposomes (ELIP) formulated with an at least partially pegylated phospholipid bi-layer shell, encapsulated nitric oxide, and encapsulated...
2016/0250251 LOW FREQUENCY GLATIRAMER ACETATE THERAPY
A method of alleviating a symptom of relapsing-remitting multiple sclerosis in a human patient suffering from relapsing-remitting multiple sclerosis or a...
2016/0250250 SKIN COMPOSITIONS AND METHODS OF USE THEREOF
Provided are therapeutic formulations and methods of use thereof.
2016/0250249 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING AUTOPHAGY IN A SUBJECT IN NEED THEREOF
The present invention provides novel methods for the modulation of autophagy and the treatment of autophagy-related diseases, including cancer,...
2016/0250248 METHOD FOR GENERATION OF BROADLY NEUTRALIZING ANTI-PATHOGEN ANTIBODIES
Methods and composition for potentiating germinal centers are disclosed herein. The methods include potentiating germinal centers to enhance antibody...
2016/0250247 VITAMIN B6 DERIVATIVES OF NUCLEOTIDES, ACYCLONUCLEOTIDES AND ACYCLONUCLEOSIDE PHOSPHONATES
Provided herein are compounds, compositions, and methods of using them to treat infections, neoplastic disease, inflammatory disease, and pain. Such compounds...
2016/0250246 ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF
The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine...
2016/0250245 Methods and Pharmaceutical Composition for the Treatment of Polyomavirus Infections
The present invention relates to methods and pharmaceutical compositions for the treatment of polyomavirus infections. In particular, the present invention...
2016/0250244 COMPOSITIONS FOR TREATING HEARTWORM INFESTATION
The present invention further relates to ivermectin, most preferably formulated as an implant for administration of pet and domestic animals. These...
2016/0250243 USE OF ICARITIN IN PREPARING MEDICAMENT FOR PREVENTING OR TREATING HEMATOCYTOPENIA
The present application relates to use of icaritin in preparing a medicament for preventing or treating hematocytopenia. Particularly, icaritin may be used to...
2016/0250242 HYPERSULFATED DISACCHARIDE FORMULATIONS
Hypersulfated disaccharides with utility in asthma or asthma related disorders are disclosed. The compounds are formulated with agents that enhance the oral...
2016/0250241 NICOTINAMIDE RIBOSIDE COMPOSITIONS FOR TOPICAL USE IN TREATING SKIN CONDITIONS
Compositions containing nicotinamide riboside (NR) are provided. NR containing compositions are used in the care or treatment of skin and skin conditions. In...
2016/0250240 METHODS AND COMPOSITIONS FOR PROMOTING ACTIVITY OF ANTI-CANCER THERAPIES
The present invention relates to a method of inhibiting growth of a cancerous cell. The method includes the step of exposing the cancerous cell to an...
2016/0250239 FEED SUPPLEMENT COMPRISING OLIGOSACCHARIDES AND MEDIUM CHAIN FATTY ACIDS
The present invention relates to a feed supplement and a feed containing this feed supplement, comprising 1) a homotrimer, heterotrimer, homotetramer and/or...
2016/0250238 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis
The present invention provides a method for the prophylaxis or treatment of systemic lupus erythematosus and/or lupus nephritis in a patient in need thereof,...
2016/0250237 SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF
The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating...
2016/0250236 PREDICTIVE BIOMARKER FOR HYPOXIA-ACTIVATED PRODRUG THERAPY
CYP2W1 levels are predictive of the probability that a cancer patient will respond favorably to cancer therapy involving administration of a hypoxia-activated...
2016/0250235 CALCIUM GLYCEROPHOSPHATE FOR TREATING AND PREVENTING RESPIRATORY DISEASES OR CONDITIONS
Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease,...
2016/0250234 Method of Treating Endometrial Tissue Disease by Altering an Epithelial to Mesenchymal Transition
The present invention is a method of treating endometrial tissue disease and in particular a method of treating endometriosis and adenomyosis by administering...
2016/0250233 ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are...
2016/0250232 A DELAYED RELEASE DRUG FORMULATION
In a delayed release formulation comprising a core containing a drug and a delayed release coating for providing intestinal release, release of the drug in the...
2016/0250231 SOLID DRUG IMPLANTS FOR INTRACOCHLEAR DELIVERY OF THERAPEUTICS FOR THE TREATMENT OF OTIC DISORDERS
The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various...
2016/0250230 THERMO-KINETIC MIXING FOR PHARMACEUTICAL APPLICATIONS
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical...
2016/0250229 CERCLAGE PESSARY CONTAINING PROGESTERONE OF PROLONGED, SUSTAINED, AND CONTINUOUS RELEASE USEFUL FOR PREVENTION...
Cerclage pessary containing progesterone homogeneously distributed in the pessary body providing a prolonged, sustained and continuous release for a period of...
2016/0250228 INTRANASAL 0.45% AND 0.48% TESTOSTERONE GEL FORMULATIONS AND USE THEREOF FOR TREATING ANORGASMIA OR HYPOACTIVE...
The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the...
2016/0250227 METHOD AND COMPOSITION FOR TRANSDERMAL DRUG DELIVERY
The invention is directed to a transdermal drug delivery composition which includes at least one physiologically active agent; and at least one volatile...
2016/0250226 DERMAL DELIVERY COMPOSITIONS AND METHODS
A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising...
2016/0250225 ENHANCED BIMATOPROST OPHTHALMIC SOLUTION
A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous...
2016/0250224 OREXIN-CONTROL OF BONE FORMATION AND LOSS
The use of orexin 1 receptor antagonists and/or orexin 2 receptor agonists thereof in the treatment of bone loss diseases is described. Such conditions include...
2016/0250223 5HT2C RECEPTOR MODULATORS
The present invention relates to novel compounds of Formula (I): ##STR00001## which act as 5HT.sub.2C receptor modulators. These compounds are useful in...
2016/0250222 DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE
The present invention provides a combined drug for an injectable depot formulation having a superior effect of preventing and/or treating polycystic kidney...
2016/0250221 INHIBITORS OF FAPP2 AND USES THEREOF
The present invention provides methods and compositions for reducing globotriaosylceramide (Gb3) accumulation and treating diseases, disorders or conditions...
2016/0250220 TREATMENT FOR PANCREATIC CANCER
The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a...
2016/0250219 SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes...
2016/0250218 PHARMACEUTICAL COMBINATION
The present invention relates to a pharmaceutical combination which may be useful for the treatment of diseases which involve cell proliferation, which involve...
2016/0250217 CRYSTALLINE FORM OF PEMIROLAST
There is provided a hemihydrate form of the sodium salt of pemirolast.
2016/0250216 INHIBITION OF HIF-2ALPHA HETERODIMERIZATION WITH HIF1BETA (ARNT)
Provided is a method of inhibiting heterodimerization of HIF-2.alpha. to HIF1.beta. (ARNT) comprising binding certain small molecules to the HIF-2.alpha. PAS-B...
2016/0250215 QUINAZOLINE COMPOUNDS
Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and...
2016/0250214 METHOD FOR TREATING LIVER DISEASES OF VARIOUS ORIGINS
The invention relates to medicine, in particular to gastroenterology, and lies in the field of treatment of liver diseases of various origins. For this...
2016/0250213 FORMULATIONS OF AZAINDOLE COMPOUNDS
A pharmaceutical composition comprises: a) 5 wt % to 95 wt % of a HCl salt of Compound (1).xH.sub.2O by the weight of the pharmaceutical composition, wherein x...
2016/0250212 DNA-PK INHIBITORS
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said...
2016/0250211 AURORA KINASE INHIBITORS
Disclosed herein inter alia are compositions and methods useful in the treatment of cancer and for modulating the activity of Aurora A kinase and/or a Myc...
2016/0250210 PHARMACEUTICAL FORMULATIONS, PROCESSES, SOLID FORMS AND METHODS OF USE RELATING TO ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
2016/0250209 CANCER TREATMENT WITH COMBINATION OF PLINABULIN AND TAXANE
This invention provides a novel cancer treatment method in which plinabulin (t-butyl-dehydrophenylahistin or NPI-2358) and a taxane compound (such as...
2016/0250208 TREATING ORGAN-SPECIFIC T CELL MEDIATED AUTOIMMUNE DISEASES
The specification provides methods of treating a subject with an organ-specific T cell mediated autoimmune disease.
2016/0250207 Treating Pain In Patients With Hepatic Impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
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