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Patent # Description
2016/0250206 METHODS AND COMPOSITIONS FOR TREATMENT OF EPITHELIAL WOUNDS
The invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based...
2016/0250205 PROCESS FOR PREPARING OXYCODONE COMPOSITIONS
In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
2016/0250204 PROCESS FOR PREPARING OXYCODONE COMPOSITIONS
In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
2016/0250203 IMMEDIATE RELEASE ABUSE-DETERRENT GRANULATED DOSAGE FORMS
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse...
2016/0250202 Mast Cell Stabilizers to Prevent or Treat Laminitis
Provided herein are mast cell stabilizers used to prevent, treat, or mitigate severity of laminitis. Mast cell stabilizers can be combined with antihistamines...
2016/0250201 DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT
The disclosure relates to a method of enhancing nicotine or other medicament concentrations in a gaseous carrier. The methods are adaptable to the delivery of...
2016/0250200 SELECTIVE SEROTONIN 2A/2C RECEPTOR INVERSE AGONISTS AS THERAPEUTICS FOR NEURODEGENERATIVE DISEASES
Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in...
2016/0250199 Opioid Receptor Ligands And Methods Of Using And Making Same
This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain...
2016/0250198 Pirfenidone Treatment for Patients with Atypical Liver Function
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone...
2016/0250197 AN INHALABLE MEDICAMENT
Accordingly, the present invention provides a solution formulation for inhalation comprising: a liquid phase; an active ingredient having a functional group...
2016/0250196 SMALL MOLECULE SECURININE AND NORSECURININE ANALOGS AND THEIR USE IN INHIBITING MYELOPEROXIDASE
The present invention relates to novel securinine and norsecurine analogs that have reduced or non-reduced gamma-delta bond. The present invention also...
2016/0250195 TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS
Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic...
2016/0250194 Methods of Making and Using Thioxothiazolidine and Rhodanine Derivatives as HIV-1 and JSP-1 Inhibitors
The present invention provides methods of making and using 5-(2-(indol-3-yl)-2-oxoethylidene)-3-phenyl-2-thioxothiazolidin-4-one derivatives having HIV-1 or...
2016/0250193 POLYMORPHIC FORMS OF 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACE- TIC ACID...
Crystalline polymorph forms of 2-(5-bromo-4-(4-cyclopropyl naphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid are described. Pharmaceutical compositions...
2016/0250192 PRODUCTION METHOD OF PHARMACEUTICAL COMPOSITION CONTAINING CANDESARTAN CILEXETIL
A production method of pharmaceutical composition contains candesartan cilexetil, comprising dissolving a water-soluble polymer and a sugar alcohol to purified...
2016/0250191 SEPARASE INHIBITORS AND USES THEREOF
In some embodiments, the present disclosure pertains to compositions with compounds that inhibit Separase activity. In additional embodiments, the present...
2016/0250190 N-METHYL PYRAZOLOANTHRONE FOR TREATMENT OF CANCER
The present invention relates to a N1-methyl-pyrazoloanthrone, e.g., a N1-methyl 1,9-pyrazoloanthrone or functional derivatives or analogues thereof to inhibit...
2016/0250189 METHODS AND COMPOSITIONS FOR PRESERVING PHOTORECEPTOR AND RETINAL PIGMENT EPITHELIAL CELLS
Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular...
2016/0250188 METHODS FOR TREATMENT OF MUSCULAR DYSTROPHIES
The present invention relates to, inter alia, treatment of muscle dystrophy (e.g., Duchenne Muscular Dystrophy), for example, using a composition, e.g., a...
2016/0250187 PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS
The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: ##STR00001## wherein A is a saturated hydrocarbon linker group...
2016/0250186 STABILIZED PHARMACEUTICAL DOSAGE FORMS COMPRISING ATRASENTAN
The present disclosure relates to: (a) methods of using stabilized pharmaceutical dosage forms comprising atrasentan, or a pharmaceutically acceptable salt...
2016/0250185 PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL
The invention relates to medicine, in particular S-Phenotropil ((S)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide) containing pharmaceutical compositions and...
2016/0250184 GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
Glucagon receptor antagonist compounds are disclosed which are of long duration of action. The compounds are useful for treating type 2 diabetes and related...
2016/0250183 PKC Delta Inhibitors for use as Therapeutics
The invention is directed to compounds that are specific inhibitors of PKC delta, and methods and compositions for the treatment and prevention of cancers and...
2016/0250182 RAB7L1 INTERACTS WITH LRRK2 TO MODIFY INTRANEURONAL PROTEIN SORTING AND PARKINSON'S DISEASE RISK
The present invention relates to methods and compositions for treating Parkinson's Disease in a subject.
2016/0250181 Alternative ACT with Natural Botanical Active GRAS Ingredients for Treatment and Prevention of the ZIKA Virus
An all-natural active ingredient herbal compositions and methods of preparing the same are provided. The novel Artemisinin Combination Therapy (ACT) consists...
2016/0250180 ESCALATING DOSING REGIMEN FOR EFFECTING WEIGHT LOSS AND TREATING OBESITY
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related...
2016/0250179 COMPOSITION FOR SUPPRESSING NEURAMINIDASE ACTIVITY COMPRISING GERANYLATED FLAVONOID DERIVED FROM PAULOWNIA...
The present invention relates to a composition for suppressing neuraminidase activity comprising a geranylated flavonoid derived from Paulownia tomentosa as an...
2016/0250178 COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or...
2016/0250177 MODIFIED DOCETAXEL LIPOSOME FORMULATIONS AND USES THEREOF
The present invention provides compositions for the treatment of cancer. The compositions include liposomes containing a phosphatidylcholine lipid, a sterol, a...
2016/0250176 TREATMENT OF CATAPLEXY
The present invention relates to a method of treating cataplexy in a subject in need thereof, comprising administering to the subject a therapeutically...
2016/0250175 COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE
The present invention relates to a combined application of isothiocyanate compounds and anti-cancer drugs, in particular to a composition, comprising: (A) a...
2016/0250174 MONOACYLGLYCEROLS FOR USE IN CONJUNCTION WITH A LIPASE INHIBITOR AND/OR DIETS LOW IN FAT AND/OR CALORIES
In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin,...
2016/0250173 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such...
2016/0250172 Neuroprotection in Demyelinating Diseases
Methods of treating neurological disorders, e.g., those characterized by demyelination and/or axonal loss (e.g., MS), are provided. The methods comprise...
2016/0250171 USE OF TALL OIL FATTY ACID IN BINDING TOXINS
The present invention relates to use of a tall oil fatty acid and/or a tall oil fatty acid which is modified by saponification in binding toxins.
2016/0250170 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF
The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an...
2016/0250169 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION
Compositions including a combination of a source of choline, a source of magnesium, and a source of L-tryptophan are provided for improving cognitive...
2016/0250168 ESTERS OF SHORT CHAINS FATTY ACIDS FOR USE IN THE TREATMENT OF IMMUNOGENIC DISORDERS
The present invention relates to short chain fatty acids (SCFA) for use in transmucosal administration to a subject for the prevention, attenuation or...
2016/0250167 Volatile Organic Compound Formulations Having Antimicrobial Activity
The present invention includes novel chemical formulations having antimicrobial activity and their methods of use thereof. In some embodiments, the formulation...
2016/0250166 METHOD FOR TREATING CHIKUNGUNYA VIRUS INFECTION
Disclosed herein is a method for the treatment of an infection with, or disease caused by, Chikungunya virus in a subject. The method includes administering to...
2016/0250165 Method of Modulating the Activity of a Nucleic Acid Molecule
The present invention relates, in general, to agents that modulate the pharmacological activity of nucleic acid molecules and, in particular, to agents that...
2016/0250164 SYSTEMIC PRO-HEMOSTATIC EFFECT OF SYMPATHICOMIMETICS WITH AGONISTIC EFFECTS ON ALFA-ADRENERGIC AND/OR...
The present invention relates to a novel use and methods of treatment using sympathicomimetic agonists with pro-hemostatic activity.
2016/0250163 COMPOUNDS SUITABLE FOR THE TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS AS WELL AS METHODS FOR THE...
The present findings point to mutant HSCs as the cause of BM neuroglial damage that compromises MSC survival and function, critically contributing to MPN...
2016/0250162 Epinephrine and Benadryl Delivery Method and Apparatus
Embodiments of the present disclosure are generally related to a method and apparatus of delivering medication to treat the symptoms of anaphylactic shock. In...
2016/0250161 COMPOSITIONS FOR THE TREATMENT OF CNS-RELATED CONDITIONS
The invention provides methods for treating CNS-related conditions with amantadine and donepezil, in which the amantadine is in an extended release form,...
2016/0250160 COMPOSITIONS FOR TREATING OR PREVENTING CARDIOVASCULAR DISEASE
Vitamin K is effective in counteracting cardiovascular disorders such as the reduction in arterial elasticity normally associated with the aging process. A...
2016/0250159 COMPOSITION, USE THEREOF, AND METHODS OF MANUFACTURING
A composition that includes at least two of: echinochrome A (2-ethyl-3,5,6,7,8-pentahydroxy-1,4-naphthoquinone); spinochrome A ...
2016/0250158 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
The instant invention provides methods and compositions for the treatment and prevention of cell proliferative disorders.
2016/0250157 Tincture For Infusing Flavonoids And Methods Of Use
Methods and formulations for infusing bioavailable flavonoid tinctures into food, beverage, cosmetic or drug products with minimal or no effect on the alcohol...
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