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Patent # Description
2016/0256495 METHOD FOR PREPARATION OF INDUCED DOPAMINERGIC PROGENITORS USING DIRECT REPROGRAMMING
The present invention relates to a method for preparing induced dopaminergic neuronal progenitors (iDPs) comprising inducing an expression of Oct4, Sox2, Klf4,...
2016/0256494 METHOD FOR COMBINED CONDITIONING AND CHEMOSELECTION IN A SINGLE CYCLE
A method of radiation-free hematopoietic stem cell (HSC) transplantation comprises administering to a mammalian subject one or two doses of 2 to 10 mg/kg body...
2016/0256493 BIOLOGIC COMPOSITION AND METHOD OF MANUFACTURE
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular...
2016/0256492 Method
A method of preparing a therapeutic cell population for clinical use from a starting population of cells comprising haematopoietic stem cells, said method...
2016/0256491 BIOLOGIC COMPOSITION AND METHOD OF MANUFACTURE
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular...
2016/0256490 ACELLULAR BIOLOGIC COMPOSITION AND METHOD OF MANUFACTURE
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular...
2016/0256489 Allograft tolerance induction
A method inducing chimerism and allograft tolerance by co-infusion of stein/progenitor-like cells and donor cells, wherein the donor cells can be bone marrow...
2016/0256488 Reducing Immune Tolerance Induced by PD-L1
The present disclosure relates to compositions and methods for reducing immune tolerance associated with CAR T cell therapy. Embodiments of the present...
2016/0256487 POLYCLONAL GAMMA DELTA T CELLS FOR IMMUNOTHERAPY
Provided herein is a method of expanding clinically-relevant quantities of polyclonal .gamma..delta. T cells that have anti-tumor, anti-viral, and...
2016/0256486 USE OF FERRIC CITRATE IN THE TREATMENT OF AND THE REDUCTION OF MORTALITY AND MORBIDITY RELATED TO ADVERSE...
Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage...
2016/0256485 TREATMENT OR PREVENTION OF PULMONARY CONDITIONS WITH CARBON MONOXIDE
A method of treating a patient having a lung condition that includes identifying a target haemoglobin-carbon monoxide level in the blood of the patient. The...
2016/0256484 Topical Compositions and Methods of Using the Same
The present invention generally relates to topical compositions and methods of using the same.
2016/0256483 POLYMER-CONJUGATED METAP2 INHIBITORS, AND THERAPEUTIC METHODS OF USE THEREOF
One aspect of the invention provides polymer conjugated MetAP2 inhibitors. While not being bound by any particular theory, it is believed that coupling the...
2016/0256482 PHARMACEUTICAL COMPOSITION FOR IMPROVING WOUND HEALING OR PROPHYLACTICALLY PREVENTING OR INHIBITING SCAR FORMATION
A pharmaceutical composition for improving wound healing is provided. The pharmaceutical composition includes (a) hyaluronic acid or its derivation, (b) an...
2016/0256481 USE OF WATER SOLUBLE PLATINUM COMPLEX IN PREPARING DRUGS FOR PREVENTION AND TREATMENT OF CANCERS
Disclosed in the present invention is the use of a water soluble platinum complex in preparing drugs for the prevention and treatment of tumors, said platinum...
2016/0256480 THERAPEUTIC COMPOSITION FOR WOUND HEALING
A therapeutic composition comprising a beta-glucan, at east one fatty acid, and at least one secondary polysaccharide, which may increase a rate of wound...
2016/0256479 NUTRITIONAL FORMULATIONS USING HUMAN MILK OLIGOSACCHARIDES FOR MODULATING INFLAMMATION
Disclosed is a nutritional composition for use in modulating or reducing inflammation in an adult or elderly individual in need thereof. In some aspects, the...
2016/0256478 METHODS OF TREATMENT
The present disclosure provides a biochemical basis of nephrotic syndrome and provides and explanation for the observed proteinuria and other effects. As a...
2016/0256477 COMPOSITION FOR PREVENTING OR TREATING NON-ALCOHOLIC LIVER DISEASE OR INSULIN RESISTANCE COMPRISING GINSENOSIDE F2
The present invention relates to a pharmaceutical composition, a health functional food, and a feed composition for the prevention, improvement, or treatment...
2016/0256476 NOVEL PARASITE THERAPY
There is disclosed herein a composition for treating extracellular parasitic infections, the composition comprising one or more of the following combinations:...
2016/0256475 METHODS OF TREATMENT OF DISEASES
The invention provides a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering a ...
2016/0256474 TOPICAL SPRAY COMPOSITION OF HALOBETASOL
The present invention relates to topical spray compositions comprising halobetasol, an emollient, a non-aqueous solvent, and a propellant. It also relates to a...
2016/0256473 Oromucosal Liquid Estradiol Compositions
The present invention relates to low dose estradiol solutions for oromucosal administration suitable in replacement therapy or suppletion of low estradiol...
2016/0256472 COMPOSITIONS AND METHODS OF ADMINISTERING SAME
A composition comprising two or more active agents in a micro-dose amount, such as a micro-dose of naltrexone in combination with a micro-dose of flumazenil,...
2016/0256471 METHOD FOR TREATING NEUROCOGNITIVE DYSFUNCTION
A method of treating corticosteroid-induced cognitive impairment comprises administering an effective amount of at least one compound of formula I, or...
2016/0256470 AQUEOUS COMPOSITION
Provided is a technology for suppressing discoloration of a halo-isoquinoline derivative-containing aqueous composition during high-temperature storage....
2016/0256469 TRICYCLIC SULFONAMIDE COMPOUNDS AND METHODS OF MAKING AND USING SAME
The invention provides tricyclic sulfonamide compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of...
2016/0256468 METHODS OF TREATING CANCER USING 3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,- ...
Provided herein are methods of treating, preventing and/or managing cancers, which comprise administering to a patient ...
2016/0256467 ANTI-PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (ANTI-PCSK9) COMPOUNDS AND METHODS OF USING THE SAME IN THE...
Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for...
2016/0256466 PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE
The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the...
2016/0256465 FORMULATIONS OF VILOXAZINE
Modified release formulations of viloxazine and methods of administering the same are disclosed. High-drug load formulations of viloxazine are further disclosed.
2016/0256464 ORALLY DISINTEGRATING TABLET COMPOSITIONS OF LAMOTRIGINE
The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with...
2016/0256463 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES
The present invention includes a composition comprising a compound, such as a 2,4,6-triamino-1,3,5-triazine, 2,4,6-triaminopyrimidine, ...
2016/0256462 ORAL LIQUID PHARMACEUTICAL COMPOSITION OF A DPP-IV INHIBITOR
The present invention relates to oral liquid pharmaceutical compositions comprising a DPP-IV inhibitor and processes for preparing the oral liquid ...
2016/0256461 METHODS FOR TREATING HAIR LOSS DISORDERS
The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of...
2016/0256460 ACTIVATORS OR STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR USE IN TREATING CHRONIC FATIGUE SYNDROME
The present invention relates in a first aspect to a therapeutically effective amount of a stimulator of the soluble guanylate cyclase and/or of an activator...
2016/0256459 SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
2016/0256458 BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases,...
2016/0256457 METHODS FOR TREATING OR PREVENTING ACUTE VASCULAR LEAK
The invention features methods, devices, pharmaceutical compositions, and kits for treating or preventing acute vascular leak. Such methods may involve...
2016/0256456 ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
2016/0256455 Treating Pain In Patients With Hepatic Impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
2016/0256454 ORAL DOSAGE FORMS FOR OXYGEN-CONTAINING ACTIVE AGENTS AND OXYL-CONTAINING POLYMER
The disclosed invention is drawn to pharmaceutical tablets that provide delivery of active agents having at least three oxygen-containing groups, a tri-oxy...
2016/0256453 OPIOID RECEPTOR ANTAGONIST FOR USE IN TREATING PATIENTS WITH SEVERE CONSTIPATION INDUCED BY HIGH OPIATE DOSAGE...
The present invention relates to a pharmaceutical composition comprising an opioid receptor antagonist, or a derivative or a pharmaceutically acceptable salt...
2016/0256452 Composition Of Opioid Receptor Antagonists For Use In Treatment Of Constipation With Highly Increased Whole Gut...
The present invention relates to a composition comprising an opioid receptor antagonist in an extended release formulation for use in treating a patient with...
2016/0256451 DOSAGE OF NALOXONE
The present invention relates to a pharmaceutical composition comprising a .mu.-receptor antagonist as an active substance, wherein the antagonist is prepared...
2016/0256450 COMPOSITIONS OF BUPRENORPHINE AND u ANTAGONISTS
The invention relates to a composition comprising buprenorphine and .mu. opioid receptor antagonist, wherein the composition is characterized by an Agonist...
2016/0256449 H3 RECEPTOR ANTAGONIST FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE
The disclosure relates to the compound 2-(cyclohexylmethyl)-N-{2-[(2S)-1-methylpyrrolidin-2-yl]ethyl}-1,2,3,4-te- trahydroisoquinoline-7-sulfonamide or a...
2016/0256448 TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases,...
2016/0256447 COMPOUNDS FOR MODULATING TRPV3 FUNCTION
The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
2016/0256446 METHODS FOR TREATING DISORDERS OR DISEASES ASSOCIATED WITH HYPERLIPIDEMIA AND HYPERCHOLESTEROLEMIA WHILE...
The present invention provides methods and compositions for treating hyperlipidemia and/or hypercholesterolemia comprising administering to the subject an...
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