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Patent # Description
2016/0256445 DIHYDROPYRIDINONE MGAT2 INHIBITORS
The present invention provides compounds of Formula (I): ##STR00001## or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the...
2016/0256444 METHOD AND COMPOSITIONS FOR TREATMENT OR PREVENTION OF INFLAMMATORY CONDITIONS
Pharmaceutical compositions and methods for treating or preventing an inflammatory condition in a patient are disclosed. The pharmaceutical compositions and...
2016/0256443 METHODS OF TREATING KERATIN HYPERPROLIFERATION DISORDERS USING mTOR INHIBITORS
A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a...
2016/0256442 LONG-ACTING INJECTABLE FORMULATIONS COMPRISING AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES THEROF
This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a...
2016/0256441 MODULATION OF MRTF-A ACTIVITY IN PATHOLOGIC FIBROSIS AND WOUND HEALING
The present disclosure concerns uses for isoxazole compounds or salts or analogs thereof for the treatment of wounds. The present disclosure also concerns...
2016/0256440 MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or...
2016/0256439 PREVENTION AND TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
Methods for preventing, treating, and/or reducing the risk of developing non-alcoholic fatty liver disease in a subject in need thereof and pharmaceutical...
2016/0256438 CATALYTIC SCAVENGERS OF ORGANOPHOSPHATES TO POTENTIATE BUTYRYLCHOLINESTERASE (hBChE) AS A CATALYTIC...
Provided are N-alkyl imidazole 2-aldoximes, including cationic imidazolium and uncharged tertiary imidazole aldoximes, and compositions and methods for making...
2016/0256437 METHODS OF TREATING ALZHEIMER'S DISEASE AND PHARMACEUTICAL COMPOSITIONS THEREOF
The present invention describes methods of treating dementia comprising administering an effective daily dose of ...
2016/0256436 USE OF EQUOL FOR TREATING ANDROGEN MEDIATED DISEASES
Equol (7-hydroxy-3(4'hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of...
2016/0256435 Composition with Pharmacological Effect for Vaporizing and Method
A composition is provided that includes a cannabinoid capable of inducing a pharmacological effect, an ester, a condensation aerosol, and a carrier liquid...
2016/0256434 USE OF STING AGONISTS TO TREAT HEPATITIS B VIRUS INFECTION
The invention includes methods of treating a subject having hepatitis B viral (HBV) infection. In certain embodiments, the method of the invention comprises...
2016/0256433 Formulations Containing Amorphous Dapagliflozin
The present invention belongs to the field of pharmaceutical industry and relates to an amorphous solid dispersion comprising at least one polymer and...
2016/0256432 COMPOSITIONS AND METHODS OF INHIBITING N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE
Compounds and pharmaceutical compositions are contemplated that inhibit N-acyl-ethanolamine-hydrolyzing acid amidase (NAAA) to so increase the concentration of...
2016/0256431 Cancer Treatments
This document provides methods and materials related to treating cancer (e.g. skin cancer). For example, methods and materials relating to the use of a...
2016/0256430 METHOD FOR TREATING SKIN INFLAMMATORY DISEASES
The present invention is directed to a method for treating skin inflammatory diseases such as dermatitis, psoriasis, and acne, and rosacea, by administering...
2016/0256429 COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS
The present invention relates to the field of medicine. It more particularly relates to the use of compounds for preventing and/or treating dyslipidemia in a...
2016/0256428 COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR INHIBITING BLOOD CANCER OR...
The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis,...
2016/0256427 HALOGENATED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE...
The present disclosure describes novel PKC-.epsilon. activators chosen from halogenated esters of unsaturated fatty acids derivatives thereof, including...
2016/0256426 Composition preventing necrotic enteritis in galloanserans
The present invention refers to the use of a glycerol ester composition of at least one short chain fatty acid for preventing and/or alleviating necrotic...
2016/0256425 Prostacyclin Compounds, Compositions and Methods of use Thereof
Prostacyclin compounds and compositions comprising the same are provided herein. Specifically, prostacyclin compounds comprising treprostinil covalently linked...
2016/0256424 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES
Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye...
2016/0256423 COMPOSITION AND METHOD FOR INCREASING THE RATE OF ALCOHOL METABOLISM AND PREVENTING HANGOVER SYMPTOMS
Compositions for increasing the rate of metabolism of alcohol in a human and preventing the symptoms of a hangover comprising amino acids of one or both of...
2016/0256422 MEDICAMENT FOR THERAPEUTIC TREATMENT OF NEUROPATHIC DISEASE
A medicament to be applied as an external preparation for therapeutic treatment of a local symptom of a neuropathic disease, which contains gabapentin or...
2016/0256421 COMPOSITION CONTAINING EUGENOL AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING ATOPIC DERMATITIS
The present invention relates to a pharmaceutical composition, a functional health food composition, a quasi-drug composition, and a cosmetic composition...
2016/0256420 Phosphate-Binding Magnesium Salts And Uses Thereof
The present invention provides, among other things, compositions and methods suitable for the treatment of hyperphosphatemia based on phosphate-binding...
2016/0256419 APPLICATION OF FLUOXETINE TO TREATMENT OF DEPIGMENTATION DISEASES
The present disclosure provides methods and pharmaceutical compositions for treating depigmentation diseases such as vitiligo or leukoctricia. The...
2016/0256418 METHODS FOR ADMINISTRATION AND FORMULATIONS FOR THE TREATMENT OF REGIONAL ADIPOSE TISSUE
Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods...
2016/0256417 NOVEL TREATMENTS FOR ATTENTION AND COGNITIVE DISORDERS, AND FOR DEMENTIA ASSOCIATED WITH A NEURODEGENERATIVE...
The present invention provides a method of treating or preventing an attention and/or cognitive disorder in a subject in need thereof, comprising administering...
2016/0256416 DOSAGE REGIMEN OF AN S1P RECEPTOR MODULATOR
S1P receptor modulators are administered following a dosage regimen providing a positive benefit-risk profile.
2016/0256415 TRANSMUCOSAL KETAMINE DELIVERY COMPOSITION
Disclosed are preparations and formulations of high thermodynamic activity lipophilic associations (LA), in which there is pairing between an ionizable...
2016/0256414 AMANTADINE COMPOSITIONS AND METHODS OF USE
Methods of nighttime administration of amantadine to reduce sleep disturbances in patient undergoing treatment with amantadine are described, as well as...
2016/0256413 COMPOSITION AND METHOD FOR TREATING NEUROLOGICAL DISEASE
Disclosed are compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, and one or more excipients, wherein at least one of the...
2016/0256412 METHOD TO SOLUBILIZE CURCUMINOIDS IN WATER
A method of solubilizing curcuminoids is disclosed wherein the method uses polyvinyl pyrrolidone and sodium bis (2-ethylhexyl) sulfosuccinate and the aqueous...
2016/0256411 TOPICAL REGIONAL NEURO-AFFECTIVE THERAPY WITH CANNABINOIDS
A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of a cannabinoid drug(s)...
2016/0256410 TOPICAL REGIONAL NEURO-AFFECTIVE THERAPY IN MAMMALS WITH CANNABINOIDS
A method of treating a disease state or condition in mammals other than humans via topical brainstem afferent stimulation therapy via the administration of a...
2016/0256409 METHOD FOR PROTECTION AND IMPROVEMENT OF LIVER HEALTH WITH MESO-ZEAXANTHIN COMPOSITIONS
A method for protection, treatment and improvement of liver health includes administering a meso-zeaxanthin composition in an effective amount to a subject in...
2016/0256408 METHOD FOR STRESS MANAGEMENT AND OVERALL HEALTH STATUS IMPROVEMENT AND COMPOSITIONS USED THEREIN
Carotenoid compositions are described for management, treatment, and/or prevention of stress by reducing cortisol levels and/or improving distribution and/or...
2016/0256407 ENERGY PATCH
A transdermal patch suitable for releasing a stimulant such as caffeine for an extended time period utilizes a pressure sensitive acrylic adhesive matrix...
2016/0256406 OLIGOMERIC/POLYMERIC SILICONE FLUIDS FOR USE IN TRANSDERMAL DRUG DELIVERY SYSTEMS
Described are oligomeric/polymeric silicone fluids useful in transdermal drug delivery systems. Also described are compositions for the transdermal delivery of...
2016/0256405 STABILIZED COMPOSITIONS CONTAINING ALKALINE LABILE DRUGS
A stabilized bioadhesive composition containing an alkaline labile drug and a method for its preparation are provided. In one aspect, the composition is a...
2016/0256404 Drugs and Gene Carrier Particles That Rapidly Move Through Mucous Barriers
The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to...
2016/0256403 BIOCOMPATIBLE GRAPHENE QUANTUM DOTS FOR DRUG DELIVERY AND BIOIMAGING APPLICATIONS
In this work we have targeted two aspects of GQDs, Size and ROS to reduce their cytotoxicity. Small size can damage cell organelles and production of ROS...
2016/0256402 SYNTHESIS OF HYPERBRANCHED AMPHIPHILIC POLYESTER AND THERANOSTIC NANOPARTICLES THEREOF
A method of making a hyperbranched amphiphilic polyester compound includes drying under vacuum a mixture of 2-(4-hydroxybutyl)-malonic acid and p-toluene...
2016/0256401 TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS
Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that...
2016/0256400 CONTROLLED RELEASE COMPOSITIONS COMPRISING A COMBINATION OF ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE
The invention relates to a controlled release composition comprising a combination of isosorbide dinitrate and hydralazine, such as hydralazine hydrochloride,...
2016/0256399 METHODS AND SYSTEMS FOR IMPROVED BIOAVAILABILITY OF ACTIVE PHARMACEUTICAL INGREDIENTS INCLUDING ESOMEPRAZOLE
The present disclosure relates to delivery systems and methods for increasing the bioavailability and increasing the absorption rate by monolithic enteric...
2016/0256398 COMPOSITIONS OF 1-[2-(2,4-DIMETHYL-PHENYLSULFANYL)-PHENYL]PIPERAZINE
Pharmaceutical compositions of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine and pharmaceutically acceptable acid addition salts thereof adapted so that...
2016/0256397 PHARMACEUTICAL FORMULATIONS OF A BRUTON'S TYROSINE KINASE INHIBITOR
Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor ...
2016/0256396 Delayed Release Tablet With Defined Core Geometry
A tablet comprising a core containing an active agent, and a coating, the core being disposed within the coating such that the coating has a thickness about a...
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