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Patent # Description
2016/0263233 METHODS, SYSTEMS AND COMPOSITIONS RELATING TO CELL CONVERSION VIA PROTEIN-INDUCED IN-VIVO CELL REPROGRAMMING
Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction...
2016/0263232 Formulations Useful in the Treatment of Proliferative Diseases Affecting the Respiratory Tract
The present application provides a pharmaceutical formulation comprising a folate receptor (FR)-targeting antineoplastic substance or composition, wherein the...
2016/0263231 Methods and Compositions Related to Viral Inhibition
Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to...
2016/0263230 Coagulation Factor-Targeting to TLT-1 on Activated Platelets
The current invention relates to: procoagulant proteins which may, for example, be fusion proteins or chemical conjugates; methods of producing said...
2016/0263229 PLATFORM DRUG DELIVERY SYSTEM UTILIZING CRYSTAL ENGINEERING AND THEANINE DISSOLUTION
A method of making a water-soluble doxorubicin-theanine cocrystal composition. The method includes the steps of providing a quantity of doxorubicin, adding a...
2016/0263228 LOW MOLECULAR WEIGHT SILK COMPOSITIONS AND STABILIZING SILK COMPOSITIONS
The present disclosure provides certain silk-fibroin compositions with particular characteristics and/or properties. In some embodiments, the disclosure...
2016/0263227 Biopolymer Drug Loading Method
A method of producing a drug-loaded Poly (Glycerol Sebacate) (PGS) comprising providing PGS; dissolving at least one drug in a solvent; incubating the PGS in...
2016/0263226 Stable Aqueous Formulations of Adalimumab
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
2016/0263225 IONIC LIQUIDS FOR TRANSDERMAL DRUG DELIVERY
The compositions and methods described herein are topically applied to the skin with negligible or no skin irritation and can direct or prevent transport...
2016/0263224 PLATFORM DRUG DELIVERY SYSTEM UTILIZING CRYSTAL ENGINEERING AND THEANINE DISSOLUTION
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution...
2016/0263223 STABLE SUBCUTANEOUS PROTEIN FORMULATIONS AND USES THEREOF
The present invention relates generally to stable formulations comprising CTLA4Ig molecules, including lyophilized, and liquid formulations for administration...
2016/0263222 SONOSENSITIVE THERAPEUTIC OR DIAGNOSTIC AGENT
The invention disclosed herein relates to a method of cavitation-induced delivery of a therapeutic or diagnostic agent to a human or animal subject. In...
2016/0263221 MULTI-RESPONSIVE TARGETING DRUG DELIVERY SYSTEMS FOR CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION
The present invention proposes the development of technology in the domain of targeted therapy and local drug delivery to the affected area of the tumor. The...
2016/0263220 FORMULATIONS OF SINGLE DOMAIN ANTIGEN BINDING MOLECULES
The invention relates to formulations of single domain antigen binding molecules, e.g., nanobody molecules, in particular formulations of TNF-binding nanobody...
2016/0263219 Treatment Methods for Rheumatoid Arthritis
The present invention provides methods for selecting treatment methods for rheumatoid arthritis based on an objective selection process (algorithm). The...
2016/0263218 BYSTANDER IMMUNE SUPPRESSION AS A PREDICTOR FOR RESPONSE TO A VACCINE
The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for...
2016/0263217 PROTEIN-SPECIFIC FORMULATIONS
The disclosure relates to supplement formulations comprising amino acids in ratios that are protein-specific. Described herein is a protein-specific supplement...
2016/0263216 ADJUVANTED FORMULATIONS OF BOOSTER VACCINES
The invention improves TdaP vaccines by including a TLR agonist in them. This agonist can provide stronger protection, longer-lasting protection, and/or can...
2016/0263215 ADJUVANT COMPOSITION, ADJUVANT PREPARATION CONTAINING SAME, AND KIT
An adjuvant composition of the present invention contains lauryl alcohol and propylene glycol. Contents of the lauryl alcohol and the propylene glycol are 0.5...
2016/0263214 CALCIUM FLUORIDE COMPOSITIONS
Compositions comprising calcium fluoride composites comprising Ca, F, and an organic molecule are provided, as are methods for their use.
2016/0263213 SALMONELLA CONJUGATE VACCINES
The invention relates to a conjugate based on Vi polysaccharide which is fragmented and a carrier protein, to compositions comprising said conjugate and to...
2016/0263212 COMPOSITIONS AND METHODS FOR TOLERIZING THE IMMUNE SYSTEM TO ALLERGENS
Compositions and methods can be used for tolerizing the immune system. The compositions can be physiologically acceptable and can include any of a wide variety...
2016/0263211 STIMULATION OF NEONATAL IMMUNITY
The present invention provides methods for inducing an immune response to a pathogen in neonatal mammals. In particular, the present invention provides methods...
2016/0263210 LIVE ATTENUATED INFECTIOUS LARYNGOTRACHEITIS VIRUS (ILTV) VACCINES AND PREPARATION THEREOF
This disclosure describes a modified live infectious laryngotracheitis virus (ILTV) developed from a strain of ILTV grown at a reduced incubation temperature,...
2016/0263209 Tissue Targeted Antigenic Activation of the Immune Response to Treat Cancers
The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one...
2016/0263208 INFLUENZA VACCINE FOR SKIN IMMUNIZATION
A method for preventing, treating or reducing the effects of influenza infection in a subject by administering an influenza vaccine to the skin of the subject....
2016/0263207 THERAPEUTIC COMPOSITION FOR TREATMENT OF GLIOBLASTOMA
The present invention is directed to compositions and methods for treating an animal diagnosed with Glioblastoma multiforme (GBM).
2016/0263206 METHODS AND COMPOSITIONS RELATED TO Th-1 DENDRITIC CELLS
Certain embodiments of the invention are directed to methods for inducing an immunologic response to a tumor in a patient using mature dendritic cells...
2016/0263205 CTL PEPTIDE EPITOPES AND ANTIGEN-SPECIFIC T CELLS, METHODS FOR THEIR DISCOVERY, AND USES THEREOF
The present invention relates to CTL peptide epitopes, high-throughput methods for their identification, and their uses. In particular, the present invention...
2016/0263204 TELOMERASE ENCODING DNA VACCINE
The invention provides a nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of...
2016/0263203 Method for Eliciting an Immune Response to Human Telomerase Reverse Transcriptase
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase....
2016/0263202 INJECTION PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a...
2016/0263201 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR ACID-LABILE DRUGS
An enteric-coated oral dosage form comprising an acid labile active pharmaceutical ingredient where the composition is substantially free of monomeric phthalic...
2016/0263200 COMPOSITIONS AND METHODS FOR PROMOTING THE MINERALIZATION OF BIOLOGICAL TISSUE
This invention relates to compositions and methods for activating and promoting mineralization in tissue that does not normally mineralize, specifically...
2016/0263199 COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK COMPRISING ADK PROTEIN AS ACTIVE INGREDIENT
The present invention relates to a composition for preventing or treating sepsis or septic shock including a Mycobacterium tuberculosis-derived adenosine...
2016/0263198 PHARMACEUTICAL COMPOSITIONS AND METHODS
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter;...
2016/0263197 HPYY(1-36) Having a Beta-Homoarginine Substitution at Position 35
The invention relates to PYY compounds having the amino acid in the position corresponding to position 35 of hPYY(1-36) substituted with beta-homoarginine and...
2016/0263196 HEMATOPOIETIC RECOVERY FROM RADIATION INJURY
Described herein are methods for the treatment of radiation injury by administration of sex steroid inhibitory (SSI) agents.
2016/0263195 COMPOSITIONS AND METHODS FOR PROTECTING THE KIDNEY FROM ISCHEMIA REPERFUSION INJURY
The effects of hepcidin treatment on mitigating IRI and acute kidney injury by decreasing iron availability and ROS-mediated cell death were tested. C57Bl/6...
2016/0263194 TREATMENTS FOR MIGRAINE AND RELATED DISORDERS
Embodiments are directed to compositions and methods of treating migraine and related neurological disorders. In certain aspects, methods and compositions are...
2016/0263193 METHOD FOR OBTAINING A CYTOKINE-RICH COMPOSITION AND COMPOSITION OBTAINED BY MEANS OF THIS METHOD
The invention relates to a method for preparing serums, said serums comprising cytokines and coagulation factors, and for preparing fibrin gel compositions,...
2016/0263192 Methods for Detecting Cardiac Damage
The present invention relates to a method for detecting heart damage in a patient. The invention also relates to methods for treatment of patients identified...
2016/0263191 Combination Treatments and Compositions for Wound Healing
Viral VEGF and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or...
2016/0263190 MODIFIED FIBROBLAST GROWTH FACTORS FOR THE TREATMENT OF OCULAR DISORDERS
Described herein are modified fibroblast growth factors (FGFs), pharmaceutical compositions, ophthalmic formulations, and medicaments that include such...
2016/0263189 TREATMENT OF A NEURODEGENERATIVE DISEASE OR DISORDER
Provided herein are methods for treating a neurodegenerative disease or disorder, or stroke using a combination of one or more RXR agonist and/or one or more...
2016/0263188 Composition
The present invention relates to a composition which comprises the following myelin basic protein peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154....
2016/0263187 USE OF MKS INHIBITOR PEPTIDE-CONTAINING COMPOSITIONS FOR TREATING NON-SMALL CELL LUNG CANCER WITH SAME
The described invention provides pharmaceutical compositions, systems and methods for treating a non-small cell lung cancer (NSCLC) solid tumor comprising a...
2016/0263186 PIF-TRANSFECTED CELLS AND METHODS OF USE
Cells transfected with DNA sequences encoding for a PreImplantation Factor (PIF) or a PIF and one or more fusion tag(s) are disclosed. Also disclosed are DNA...
2016/0263185 MODIFIED BINDING PROTEINS INHIBITING THE VEGF-A RECEPTOR INTERACTION
The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety...
2016/0263184 METHODS OF CONTROLLING VASCULARITY USING RAVER2 AS A MEDIATOR FOR EXPRESSION OF VEGF RECEPTOR SFIT1
Methods of treating a condition in a subject resulting from abnormally high VEGF signaling through membrane-bound receptors. Such a method can include...
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