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Patent # Description
2016/0281106 Bicistronic Expression Vector For Antibody Expression And Method For Producing Antibody Using Same
The present invention relates to a bicistronic expression vector for antibody expression, an animal cell transfected with the expression vector, and a method...
2016/0281105 PHI-4 Polypeptides and Methods For Their Use
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal...
2016/0281104 NOVEL ACTIVITY OF AHPF PROTEIN OF PSEUDOMONAS AERUGINOSA, AND USE THEREFOR
The present invention relates to an AhpF protein which has thioredoxin reductase, peroxidase, and chaperone activities and is derived from Pseudomonas...
2016/0281103 WHEAT WITH INCREASED NUMBER OF GRAINS AND METHOD FOR PRODUCING THE SAME, AND AGENT FOR INCREASING THE NUMBER OF...
The Vrs1 gene was found to be highly expressed in the pistils of sterile lateral spikelets of two-row barley, showing that the VRS1 protein suppresses the...
2016/0281102 DNA Having Anther-Specific Promoter Activity, and Utilization Thereof
A DNA having an anther-specific promoter activity, wherein the DNA is selected from the group consisting of the following (a) to (d): (a) a DNA containing a...
2016/0281101 COMPOSITIONS AND METHODS CONTAINING A SPECIFIC LEAF PROMOTER TO MODIFY THE EXPRESSION OF GENES OF INTEREST IN...
The present invention relates to a polynucleotide sequence capable of efficiently modifying the expression of one or more genes of interest in leaves, in...
2016/0281100 GENETIC CONTROL OF AXILLARY BUD GROWTH IN TOBACCO PLANTS
This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying...
2016/0281099 FORMULATIONS AND METHODS FOR CONTROL OF WEEDY SPECIES
A formulation is provided for application to a host plant to reduce, inhibit or impair one or more of growth and development of the host plant. A method of...
2016/0281098 METHOD FOR PRODUCING PROTEIN USING PLANT
A method for producing a useful protein using a plant of the present invention comprises the steps of: cultivating the plant (cultivation step); infecting...
2016/0281097 METHOD FOR PRODUCING EXPRESSION PRODUCT OF EXOGENOUS GENE IN YEAST, REGULATOR OF EXPRESSION IN YEAST, AND USE...
A method for producing an expression product of an exogenous gene in a yeast, including using at least one yeast gene terminator regions selected based on...
2016/0281096 RECOMBINANT MICROORGANISM HAVING ENHANCED 2,3-BUTANEDIOL PRODUCING ABILITY AND METHOD FOR PRODUCING...
Disclosed herein is a recombinant microorganism having enhanced 2,3-butanediol producing ability, wherein a pathway for converting pyruvate to acetyl-CoA, a...
2016/0281095 Alkynyl-Derivatized Cap Analogs, Preparation and Uses Thereof
Alkynyl-derivatized cap analogs, alkynyl-modified capped RNA, 1,4-disubstituted triazole-derivatized capped RNA, methods of preparation, methods of isolation,...
2016/0281094 TECHNOLOGIES FOR MANUFACTURING AN ENGINEERED BIO-SYSTEM
Technologies for manufacturing an engineered biological system include determining a plurality of functions to be performed by the engineered biological system...
2016/0281093 METHODS AND COMPOSITIONS FOR INTERFERENCE WITH DNA POLYMERASE AND DNA SYNTHESIS
Disclosed are methods and compositions for inhibiting DNA synthesis in a cell using RNA. Inhibition of DNA synthesis by RNA can be used, for example, in...
2016/0281092 ANTISENSE COMPOSITION AND METHOD FOR TREATING MUSCLE ATROPHY
A method and compound for treating skeletal muscle mass deficiency in a human subject are disclosed. The composition is an oligomer of morpholino subunits and...
2016/0281091 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF MYC BY DOUBLE-STRANDED RNA
This invention relates to compounds, compositions, and methods useful for reducing MYC target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate...
2016/0281090 MODIFIED DNA QUADRUPLEX-FORMING OLIGONUCLEOTIDES AND METHODS OF USE
Oligonucleotides according to the following Formula I are provided herein: 5'-X.sub.a-Q-Y.sub.b-3' wherein X and Y are each independently selected from the...
2016/0281089 PREVENTION OF VIRAL INFECTIVITY
The present invention concerns the inactivation of viral infectivity in a cell-free environment as well as the preparation of a pharmaceutical agent and a...
2016/0281088 TREATMENT OF DISCS LARGE HOMOLOG (DLG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO DLG
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Discs large homolog (DLG), in particular, by...
2016/0281087 Modulation of T Cell Signaling Threshold and T Cell Sensitivity to Antigens
MicroRNAs (miRNAs) are a diverse and abundant class of .about.22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by...
2016/0281086 QUANTIFICATION AND SPATIO-TEMPORAL TRACKING OF A TARGET USING A SPHERICAL NUCLEIC ACID (SNA)
The present invention relates to methods of detecting and tracking a target molecule using a nanoparticle wherein the nanoparticle comprises a polynucleotide...
2016/0281085 MOLECULAR TARGETS FOR SELECTIVE ERADICATION OF SENESCENT CELLS
Compositions and methods for selective partial or complete eradication of senescent cells in a mammal are provided. The involves inhibition of the expression...
2016/0281084 RNA INTERFERENCE SUPPRESSION OF NEURODEGENERATIVE DISEASES AND METHODS OF USE THEREOF
The present invention is directed to small interfering RNA molecules (siRNA) targeted against nucleic acid sequence that encodes huntingtin or ataxin-1, and...
2016/0281083 MODULATION OF TIMP1 AND TIMP2 EXPRESSION
Provided herein are compositions, methods and kits for modulating expression of target genes, particularly of tissue inhibitor of metalloproteinase 1 and of...
2016/0281082 MAGNETIC INORGANIC IRON-BASED NANOPARTICLES
A nanoparticle, which has a metal oxide core and a cerium shell is provided. The weight ratio of the cerium within the shell to the metal oxide in the core is...
2016/0281081 PROGRAMMED DROPLET RUPTURE FOR DIRECTED EVOLUTION
A method of directed evolution screening includes selecting a protein expression platform for an evolution target, expressing a key rupture gene configured to...
2016/0281080 METHOD AND MATERIALS FOR ISOLATION OF NUCLEIC ACID MATERIALS
A method for nucleic acid isolation comprising: receiving a binding moiety solution within a process chamber; mixing the binding moiety solution with a...
2016/0281079 BIOLOGIC SAMPLE COLLECTION DEVICES AND METHODS OF PRODUCTION AND USE THEREOF
Collection devices and kits for biological sample collection include a biologic sample collection device having a hydrophilic swab matrix that includes a...
2016/0281078 METHODS FOR SEPARATING NUCLEIC ACIDS BY SIZE
The present invention pertains to a method for isolating nucleic acids by size from a sample comprising nucleic acids of different sizes using an anion...
2016/0281077 MEDIUM AND METHOD FOR CULTURING EUGLENA AND METHOD FOR REDUCING PHOTOINHIBITION IN EUGLENA
A medium for culturing Euglena includes a cell membrane-permeable electron mediator that includes a biocompatible moiety and a redox-active moiety. A method...
2016/0281076 IMPROVED VARIANT OF D-PSICOSE 3-EPIMERASE AND USES THEREOF
The present invention relates to an improved variant of a D-psicose 3-epimerase and its uses.
2016/0281075 USE OF GALERINA MARGINATA GENES AND PROTEINS FOR PEPTIDE PRODUCTION
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in...
2016/0281074 MODIFIED KZ144 ENDOLYSIN SEQUENCE
The present invention relates to polypeptides comprising an amino acid sequence exhibiting at least about 90% sequence identity with the sequence of SEQ ID NO:...
2016/0281073 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs,...
2016/0281072 CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors...
2016/0281071 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to lipase variants and methods of obtaining them. The present invention also relates to polynucleotides encoding the variants;...
2016/0281070 L-THREONINE-PRODUCING MICROORGANISM AND PRODUCTION METHOD FOR L-THREONINE USING THE SAME
The present application relates to an L-threonine-producing microorganism and a production method for L-threonine using the same, and more specifically, to a...
2016/0281069 NUCLEIC ACID SEQUENCE SEGMENT FOR ENHANCING PROTEIN EXPRESSION
An isolated or a purified nucleic acid sequence for enhancing expression levels of a protein of interest, in 5' to 3' direction, comprises: a cytomegalovirus...
2016/0281068 BIOCATALYSTS FOR EZETIMIBE SYNTHESIS
The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods...
2016/0281067 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF AZETIDINONE
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase...
2016/0281066 MITOGEN-ACTIVATED PROTEIN KINASE-DEPENDENT RECOMBINANT VACCINIA VIRUS (MD-RVV) AND USE THEREOF
This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of...
2016/0281065 Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And...
The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with...
2016/0281064 LIVER TISSUE CULTURING DEVICE, LIVER TISSUE CULTURING SYSTEM, LIVER TISSUE CULTURING METHOD, AND LIVER FUNCTION...
A device for culturing a liver tissue has a culture chamber to which at least two flow channels, which are at least for introducing and discharging a culture...
2016/0281063 METHODS FOR CELL REPROGRAMMING AND GENOME ENGINEERING
Methods for producing engineered induced pluripotent stem (iPS) cells are provided comprising introducing a first nucleic acid into somatic cells for...
2016/0281062 METHOD FOR DIFFERENTIATING INDUCED PLURIPOTENT STEM CELLS INTO RENAL PROXIMAL TUBULAR CELL-LIKE CELLS
There is provided a method of differentiating an induced pluripotent stem cell (iPSC) into a renal proximal tubular cell (PTC)-like cell. The method comprises...
2016/0281061 TISSUE ARRAY FOR CELL SPHEROIDS AND METHODS OF USE
The present invention generally features methods of preparing a microarray of cell spheroids, methods of preparing a micromold for embedding spheroids for...
2016/0281060 Serum-Free Chemically Defined Cell Culture Medium
Embodiments of chemically defined cell culture media containing nutrients and growth factors free of any serum for culturing cells such as mesenchymal stem...
2016/0281059 METHODS AND PRODUCTS FOR TRANSFECTION
The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these...
2016/0281058 AGENTS AND METHODS FOR INHIBITING HUMAN PLURIPOTENT STEM CELL GROWTH
The present invention relates to compositions and methods for inhibiting or suppressing undifferentiated or pluripotent stem cell growth and proliferation in a...
2016/0281057 AGENT FOR IMPROVING SPERM-MOTILITY
The present invention addresses the problem of providing an agent for improving sperm-motility, in particular, an agent for improving forward-sperm-motility,...
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