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Patent # Description
2016/0279156 COMPOSITION FOR PREVENTING OR TREATING COLON CANCER, CONTAINING 3,6-ANHYDROL-GALACTOSE
The present invention relates to a composition for preventing or treating colon cancer, containing 3,6-anhydro-L-galactose, and more specifically, provides...
2016/0279155 NOVEL FORMULATIONS
Provided are novel formulations of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate as described below and uses thereof. Also...
2016/0279154 MITOCONDRIALLY-TARGETED TIMOQUINONES AND TOLUQUINONES
The invention provides timoquinone-based mitochondrially-targeted antioxidants (MTAs) and methods for their use.
2016/0279153 BALSALAZIDE FORMULATIONS AND MANUFACTURE AND USE THEREOF
The invention relates to formulations and dosage schedules of balsalazide. The invention further relates to methods of producing pharmaceutical formulations of...
2016/0279152 PHARMACEUTICAL TETRACYCLINE COMPOSITION FOR DERMATOLOGICAL USE
Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises...
2016/0279151 ORAL AND INJECTABLE FORMULATIONS OF TETRACYCLINE COMPOUNDS
Injectable and oral formulations of a tetracycline compound are described. In one embodiment, the invention pertains to an oral formulation of a 9-aminomethyl...
2016/0279150 Combination of Selected Analgesics and Cox-II Inhibitors
Combinations of certain analgesics with COX-II inhibitors, related pharmaceutical compositions, including advantageous galenical forms containing these...
2016/0279149 System and Method for Diagnosis and Treatment
This invention relates the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the treating or preventing treatment resistant prostate...
2016/0279148 System and Method for Diagnosis and Treatment
This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR...
2016/0279147 MONOLITHIC INTRAVAGINAL RINGS COMPRISING PROGESTERONE AND METHODS OF MAKING AND USES THEREOF
The present invention relates to monolithic intravaginal rings comprising progesterone, methods of making, and uses thereof. The intravaginal rings comprise...
2016/0279146 METHODS AND PHARMACEUTICAL FORMULATIONS FOR TREATMENT OF SELECTIVE ESTROGEN-RECEPTOR MODULATOR-INDUCED ADVERSE...
The invention related to methods of treatment of an individual suffering from or at risk of suffering from a selective estrogen-receptor modulator (SERM)...
2016/0279145 NOVEL CYTOTOXIC AGENTS THAT PREFERENTIALLY TARGET LEUKEMIA INHIBITORY FACTOR (LIF) FOR THE TREATMENT OF...
Described herein are new anti-cancer compounds and methods of using such compounds, acting through a new mechanism of action by simultaneous inhibition of...
2016/0279144 6-Substituted Estradiol Derivatives for Use in Remyelination of Nerve Axons
Disclosed is a method of remyelinating axons with 6-substituted estradiol compounds of the formula ##STR00001## The methods can be used to treat a variety of...
2016/0279143 TOPICAL TREATMENT FOR CHEMOTHERAPY INDUCED EYELASH LOSS OR HYPOTRICHOSIS USING PROSTAMIDE F2 ALPHA AGONISTS
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present...
2016/0279142 COMBINATIONS OF A PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUND AND A CDK4/6 INHIBITOR COMPOUND FOR THE...
Methods and compositions are provided for treating cancer in patients with a therapeutic combination comprising a therapeutically effective amounts of...
2016/0279141 COMBINATION THERAPY FOR CANCER USING BROMODOMAIN AND EXTRA-TERMINAL (BET) PROTEIN INHIBITORS
The present invention provides methods for treating cancer using combinations of bromodomain and extra-terminal (BET) protein inhibitors and certain...
2016/0279140 CEFTOLOZANE ANTIBIOTIC COMPOSITIONS
This disclosure provides pharmaceutical compositions comprising ceftolozane, pharmaceutical compositions comprising ceftolozane and tazobactam, methods of...
2016/0279139 AN IMPROVED PROCESS FOR MANUFACTURING STERILE OPHTHALMIC PHARMACEUTICAL SUSPENSIONS
The present invention provides a process of manufacturing a sterile, ophthalmic pharmaceutical suspension comprising sterile active ingredient(s) such as...
2016/0279138 AEROSOLIZED FLUOROQUINOLONES AND USES THEREOF
Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone...
2016/0279137 FINAFLOXACIN SUSPENSION COMPOSITIONS
The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a suspension...
2016/0279136 FORMULATIONS OF VILOXAZINE
Modified release formulations of viloxazine and methods of administering the same are disclosed. High-drug load formulations of viloxazine are further disclosed.
2016/0279135 THERAPIES FOR TREATING MYELOPROLIFERATIVE DISORDERS
Provided herein are methods, compositions, and kits for treating myeloproliferative disorders or neoplasms, including polycythemia vera, primary myelofibrosis,...
2016/0279134 ORAL PHARMACEUTICAL FILM FORMULATION FOR BITTER TASTING DRUGS
The invention relates to a pharmaceutical film formulation comprising one or more bitter-tasting drug(s) or pharmaceutically acceptable salts thereof, one or...
2016/0279133 PHARMACEUTICAL COMPOSITION OF SILDENAFIL CITRATE IN THE FORM OF A SUSPENSION FOR ORAL USE
The present invention refers to a pharmaceutical composition of sildenafil citrate in the form of a suspension for administration orally that comprises water...
2016/0279132 PYRAZOLOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER
Compound of Formula I: ##STR00001## are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use...
2016/0279131 DEPOT FORMULATIONS
Disclosed are formulations and related methods that comprise a non-polymeric, non-water soluble high viscosity liquid carrier material having a viscosity of at...
2016/0279130 COMPOSITIONS AND METHODS FOR INCREASING ENERGY METABOLISM
Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or...
2016/0279129 PHARMACEUTICAL FORMULATIONS
This invention relates to solid oral pharmaceutical formulations of (S)-methyl (1-((4-(3-(5-chloro-2-fluoro-3-(methyl ...
2016/0279128 PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS
Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or prevent diseases or...
2016/0279127 HETEROARYL COMPOUNDS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
2016/0279126 COMPOSITION FOR REDUCING FREQUENCY OF URINATION, METHOD OF MAKING AND USE THEREOF
Pharmaceutical compositions for reducing frequency of urination are disclosed. The pharmaceutical compositions comprise one or more analgesic agents and a PDE5...
2016/0279125 PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2- ...
The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2- ...
2016/0279124 Method for Treating Addiction
The present invention provides a method of treating a patient suffering from addiction, having the steps of administering to the patient a controlled release...
2016/0279123 TREATMENT OF CANCER USING A SMAD3 INHIBITOR
The present invention resides in the discovery that Smad3, a key downstream mediator of TGF-.beta. signaling, plays a critical role in development and...
2016/0279122 PHENYL LINKED QUINOLINYL MODULATORS OF RORgammat
The present invention comprises compounds of Formula I. ##STR00001## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, and R.sup.9...
2016/0279121 5-CHLORO-4-HYDROXY-1-METHYL-2-OXO-N-PHENYL-1,2-DIHYDROQUINOLINE-3-CARBOXAM- IDE, SALTS AND USES THEREOF
The subject invention provides 5-chloro-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxa- mide, its salts and uses.
2016/0279120 NOVEL HYDROXY-6-HETEROARYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS
Compounds of the formula Ia***** ##STR00001## in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors,...
2016/0279119 BIS-QUATERNARY AMMONIUM SALTS AS PAIN MODULATING AGENTS
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropathic pain and nociceptive pain.
2016/0279118 TREATMENT OF MULTIPLE SCLEROSIS WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD
This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering...
2016/0279117 Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical...
2016/0279116 THERAPEUTIC USES OF NICOTINE
The use of nicotine for treating renal pain is described. It is believed that renal pain, such as renal pain caused by renal ischemia or renal reperfusion, can...
2016/0279115 POLYMORPHS OF COCRYSTALS OF P-COUMARIC ACID:NICOTINAMIDE
Polymorphs, Forms II and III, of cocrystals of p-coumaric acid and nicotinamide in a 1:1 molar ratio. Pharmaceutical compositions containing Forms II or III,...
2016/0279114 PHARMACEUTICAL COMPOSITION COMPRISING GLUTARIMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF EOSINOPHILIC...
The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their...
2016/0279113 TREATMENT OF CANCER WITH SORAFENIB
The present invention provides compositions and methods for treating specific cancers with effective amounts of sorafenib.
2016/0279112 Methods And Compositions To Inhibit Symptoms Associated With Veisalgia
The present invention relates to a method of reducing or preventing the symptoms associated with the intake of alcohol. The method comprises administering to a...
2016/0279111 TETRAHYDROPYRIDOETHERS FOR THE TREATMENT OF AMD
A medication comprising tetrahydropyridoethers for use in the treatment of AMD.
2016/0279110 COMPOSITIONS AND METHODS FOR TREATING CANCER
Provided herein are compositions and methods for treating cancer.
2016/0279109 SUBSTITUTED IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TrkA) INHIBITORS
The present application relates to a series of substituted imidazo[1,2-a]pyridine compounds of formula (I), ##STR00001## pharmaceutically acceptable salts,...
2016/0279108 TARGETED MTOR INHIBITORS
The present invention is directed to drug conjugates of mTOR inhibitors comprising an mTOR inhibitor, such as rapamycin, conjugated to hyaluronic acid by a...
2016/0279107 BENZOTHIAZOLONE COMPOUND
The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form ##STR00001## a method for manufacturing the...
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