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Patent # Description
2016/0296648 Y-90-LABELED ANTI-CD22 ANTIBODY (EPRATUZUMAB TETRAXETAN) IN REFRACTORY/RELAPSED ADULT CD22+ B-CELL ACUTE...
The present invention relates to use of .sup.90Y-conjugated anti-CD22 antibody for treatment of relapsed/refractory acute lymphoblastic leukemia (ALL)....
2016/0296647 METHODS TO DIAGNOSE DEGENERATIVE DISC DISEASE
Methods are provided that better describe, and localize the pain generator or suspected pain generator in and around spinal discs in relation to neck or back...
2016/0296646 ALKYLPHOSPHOCHOLINE ANALOGS FOR MULTIPLE MYELOMA IMAGING AND THERAPY
It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by multiple myeloma tumor cells. The alkylphophocholine...
2016/0296645 HYPERPOLARIZED 1-13C-1,1-BIS(ACETOXY(METHYL))-2,2'-CYCLOPROPANE AS METABOLIC MARKER FOR MR
1-.sup.13C-1,1-Bis(acetoxy(methyl))-2,2'-cyclopropane of formula (I): The compound can be hyperpolarized and used as a contrast agent in .sup.13C Magnetic...
2016/0296644 ANTICANCER DRUG, COMPRISING A COPPER RADIOISOTOPE
The object of the present invention is a drug for the therapeutic treatment of tumours, also usable as diagnostic agent and therapeutic agent for the...
2016/0296643 PRODUCTION OF MAGNETIC NANOPARTICLES IN RECOMBINANT HOST CELLS
The present invention relates to a recombinant host cell, comprising in its genome preferably heterologous gene expression cassettes capable of being expressed...
2016/0296642 Compositions and Methods to Image and Quantify Inflammation
Compositions and methods for assessing inflammation in a subject. The present disclosure provides compositions for labeling leukocytes with a ...
2016/0296641 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING
Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use...
2016/0296640 BIONANOFLUID FOR USE AS A CONTRAST, IMAGING, DISINFECTING AND/OR THERAPEUTIC AGENT
A bionanofluid includes a carbon-based nanomaterial substantially mono-dispersed in a fluid. The carbon-based nanomaterial is surface modified with a polar...
2016/0296639 NEAR-INFRARED QUENCHING GROUP
[Problem] To provide a novel near-infrared quencher. [Solution] A compound represented by general formula (I) or a salt thereof. ##STR00001##
2016/0296638 GENE THERAPY TO PREVENT REACTIONS TO ALLERGENS
This invention is directed to a vector which comprises a promoter operably linked to a nucleic acid sequence encoding a therapeutic gene that blocks allergic...
2016/0296637 Method for improving survival after radiation exposure using mesenchymal stem cells as vehicles for...
A method for improving survival after radiation exposure using mesenchymal stem cells as vehicles to deliver extracellular superoxide dismutase is provided....
2016/0296636 FUNCTIONALIZING NANOFIBRES
Methods for functionalizing the surface of nanofibre substrates, including electrospun fibres and non-woven or woven mats of fibres are described....
2016/0296635 Affinity Hydrogels for Controlled Protein Release
The present invention relates to novel porous matrix composites and formulations for controlled protein delivery and the uses therefor. The present invention...
2016/0296634 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using...
2016/0296633 COMBINING ANTI-HLA-DR OR ANTI-TROP-2 ANTIBODIES WITH MICROTUBULE INHIBITORS, PARP INHIBITORS, BRUTON KINASE...
The present invention relates to combination therapy with drugs, such as microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or PI3K inhibitors,...
2016/0296632 ENGINEERED GLYCOPROTEINS AND USES THEREOF
The present invention provides for novel glycoproteins comprising therapeutically useful polypeptides, or fragments or variants thereof, conjugated to...
2016/0296631 DRUG DELIVERY POLYMER AND USES THEREOF
Described herein are platinum-based brush-arm star polymers (Pt-BASPs), or a pharmaceutical composition thereof, for delivery of platinum-based agents, such as...
2016/0296630 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES
Described are methods, uses, and kits for utilizing a targeted ligand conjugate in combination with a thiol inhibitor or a system x.sub.c.sup.- inhibitor for...
2016/0296629 IRON COMPLEXING AGENT AND USES THEREOF IN THE TREATMENT AND PREVENTION OF COLORECTAL CANCER
A complex comprising a non-absorbable portion attached to an iron chelator moiety, a composition comprising the complex and the use of the complex in the...
2016/0296628 NANOPARTICLE DELIVERY SYSTEMS FOR CYTOLYTIC PEPTIDE PRODRUGS
Compositions and methods of treatment using conjugates of pore-forming compounds coupled to blocking segments by protease-cleavable linkers and absorbed onto...
2016/0296627 INTRACAMERAL IMPLANT FOR TREATMENT OF AN OCULAR CONDITION
The disclosure teaches precisely engineered biodegradable drug delivery systems and methods of making and utilizing such systems. In aspects, the biodegradable...
2016/0296626 Use of Heptyl Glucoside as Skin Penetration Enhancer in Transdermal Pharmaceutical Compositions
The present disclosure refers to heptyl glucoside included, as a natural solubilizer and as a skin penetration enhancer, in transdermal pharmaceutical...
2016/0296625 Natural Solubilizer Agent Comprising a Synergistic Blend of Heptyl Glucoside and Olive Oil Glycereth-8 Esters...
The present disclosure refers to a synergistic blend of heptyl glucoside and olive oil derivatives, which is included as a natural solubilizer agent in...
2016/0296624 Pharmaceuticals for Oral Delivery
The present invention provides pharmaceutical compositions suitable for oral delivery and methods of treating subjects in need thereof. The pharmaceutical...
2016/0296623 HYDROGEL POLYMERIC COMPOSITIONS AND METHODS
Some aspects of this disclosure relate to a method of treating an ophthalmic disease affecting an eye of a patient comprising forming a covalently-crosslinked...
2016/0296622 FORMULATIONS OF BENDAMUSTINE
Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter...
2016/0296621 FORMULATIONS OF BENDAMUSTINE
Methods of treatment using bendamustine formulations designed for small volume intravenous administration are disclosed. The methods conveniently allow shorter...
2016/0296620 HMGN POLYPEPTIDES AS IMMUNE ENHANCERS AND HMGN ANTAGONISTS AS IMMUNE SUPPRESSANTS
A method of enhancing an antigen-specific immune response in a host comprising administering to the host an HMGN polypeptide comprising at least one of HMGN1,...
2016/0296619 CMV VACCINES
Provided herein are genetically modified arenaviral vectors suitable as vaccines for prevention and treatment of cytomegalovirus infections and reactivation....
2016/0296618 EPSTEIN-BARR-VIRUS VACCINE
The present invention relates to a vaccine comprising a particle, said particle comprising (i) at least one Epstein-Barr virus (EBV) structural polypeptide,...
2016/0296617 Immunogenic Composition for MERS Coronavirus Infection
Described herein are immunogenic compositions for preventing infection with Middle East respiratory syndrome coronavirus (MERS-CoV) wherein the immunogenic...
2016/0296616 IMMUNOGENIC COMPOSITIONS AND USES THEREOF
Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.
2016/0296615 FISH VACCINE
The present document discloses a new species of Bizionia, herein denoted Bizionia piscinecroseptica and a reference strain of this bacterium denoted Bizionia...
2016/0296614 FISH VACCINE
The present document discloses a new species of Aliivibrio, herein denoted Aliivibrio friggiae. A strain Aliivibrio friggiae, denoted Aliivibrio sp. 130206K7F2...
2016/0296613 DETECTION/MEASUREMENT OF MALARIA INFECTION DISEASE UTILIZING NATURAL IMMUNITY BY HEMOZOIN INDUCTION, SCREENING...
The instant invention is to provide a method for detecting and measuring malaria infection utilizing the induction by hemozoin (HZ); a method for screening a...
2016/0296612 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING CANCER
A immunogenic composition is provided for use in methods for treating or preventing the development of a cancer, comprising a nucleic acid sequence encoding a...
2016/0296611 Controlled Delivery of TLR Agonists in Structural Polymeric Devices
The present invention comprises compositions, methods, and devices for creating an stimulating an antigen-specific dendritic cell immune response. Devices and...
2016/0296610 THERAPEUTIC CANCER VACCINE BASED ON STRESS PROTEINS RENDERED IMMUNOGENIC
The invention describes a method for preparing a composition comprising tumour cell stress proteins, said method comprising the following steps: providing...
2016/0296609 DENDRITIC CELL ASGPR TARGETING IMMUNOTHERAPEUTICS FOR MULTIPLE SCLEROSIS
Methods and compositions for treating multiple sclerosis using dendritic cell anti-ASGPR antibodies fused to myelin basic protein or myelin oligodendrocyte...
2016/0296608 TREATMENT METHODS USING ATOXIC NEUROTOXIN DERIVATIVES
The present invention relates to a treatment method. This method involves contacting a subject with an isolated, physiologically active, atoxic derivative of a...
2016/0296607 METHODS OF USING A FIXED DOSE OF A CLOTTING FACTOR
The present invention provides methods of administering a clotting factor by a fixed dosing regimen; methods of reducing, ameliorating, or preventing one or...
2016/0296606 Cellular Factor-Containing Solution Compositions for the Treatment of Rhinovirus Infection and Symptoms
The invention is directed to methods for treating rhinovirus infection and symptoms. The invention is further directed to reducing inflammation of the nasal...
2016/0296605 METHODS AND COMPOSITIONS FOR TREATING HUNTINGTON'S DISEASE
Disclosed herein are methods and compositions for diagnosing, treating or preventing Huntington's Disease.
2016/0296604 Peptide Having Angiogenesis Inhibitory Activity and Composition Containing Same
The present invention relates to a peptide having angiogenesis inhibition activity and pharmaceutical composition comprising thereof. More specifically, the...
2016/0296603 SYNERGISTIC GLYCOCALYX TREATMENT COMPOSITIONS AND METHODS
Compositions and methods for treating endothelial glycocalyx include glucosamine, hyaluronan and/or fucoidan, and one or more antioxidants, such as superoxide...
2016/0296602 Dosing Regimen
The present invention relates to a long acting insulin analogue for use in reducing the risk of hypoglycaemia in a patient suffering from diabetes and...
2016/0296601 Treatment of Type 2 Diabetes Mellitus Patients
The present invention refers to lixisenatide for use in the reduction of progression of urinary albumin excretion in a type 2 diabetes mellitus patient.
2016/0296600 Relaxin Prodrugs
The present invention relates to a carrier-linked relaxin prodrug, pharmaceutical compositions comprising said prodrug, their use as medicaments for the...
2016/0296599 COMPOSITIONS FOR DELIVERING PEPTIDE YY AND PYY AGONISTS
The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide...
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