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Estrogen Receptor Beta Agonists for Use in Treating Mesothelioma
The invention provides a treatment of mesothelioma, especially malignant pleural mesothelioma, using an estrogen receptor .beta. subtype (ER.beta.) agonist,...
ANTIPARASITIC USE OF ISOXAZOLINE COMPOUNDS
This invention relates to methods for preventing infestations of animals and their environments with adult fleas by systemic administration of isoxazoline...
PHARMACEUTICAL COMPOSITION COMPRISING A RYANODINE RECEPTOR ANTAGONIST FOR
FACILITATING WOUND HEALING
The invention relates to the use of pharmaceutical compositions containing as the active agent a compound of formula I in the treatment of dermal wounds. The...
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam...
PHARMACEUTICAL COMPOSITIONS COMPRISING
4-[1-(2,3-DIMETHYLPHENYL)ETHYL]-3HIMIDAZOLE DERIVATIVES FOR TREATING
The present invention relates to pharmaceutical compositions, containing 4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, (S) 4 ...
INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE
Provided are compositions for inhibiting a biological activity of an aldo-keto reductase family 1, member C3 (AKR1C3) polypeptide. In some embodiments, the...
INHIBITORS OF BETA1-INTEGRIN AND METHODS OF USE
The present disclosure provides compositions and methods for inhibiting .beta.1-integrin expression and functionality, and for addressing any condition...
COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL MALIGNANCIES
A compound represented by Formula I is provided for use in the treatment of a hematological malignancy in a subject in need thereof. Also provided are...
USE OF INDOLYL AND IDOLINYL HYDROXAMATES FOR TREATING NEURODEGENERATIVE
DISORDERS OR COGNITIVE DECICITS
The present invention relates to novel use of indolyl and indolinyl hydroxamates. Particularly, the invention relates to use of indolyl and indolinyl...
METHODS OF MODULATING VARIOUS BIOMARKERS WITH CURAXINS
The present invention relates to improved methods for diagnosing and/or treating cancer with a curaxin, including curaxin 137.
Provided are pharmaceutical compositions comprising (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane, in free or pharmaceutically acceptable salt form....
Provided are novel methods comprising administering a therapeutically effective amount of (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane, in free or ...
COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING
Compounds of formula I ##STR00001## are useful in treating and/or preventing inflammatory diseases.
METHODS TO MITIGATE INJURY FROM RADIATION EXPOSURE BY ADMINISTERING CXCR4
ANTAGONIST DURING DECISIVE TREATMENT...
Mitigating radiation induced injury to a mammal that has been exposed to radiation by administering a pharmaceutically effective amount of a composition...
DRUG FOR PREVENTING, TREATING OR PREVENTING METASTASIS OF GIANT CELL TUMOR
THAT OCCURS IN BONE OR SOFT PARTS,...
The present invention provides an agent for prophylactic treatment, therapeutic treatment, or prevention of metastasis of giant cell tumor occurring in a bone...
VITAMINS C AND K FOR TREATING POLYCYSTIC DISEASES
Provided herein is a pharmaceutical composition comprising vitamin C and chromium-free vitamin K, and optionally one or more pharmaceutically acceptable...
SODIUM ASCORBATE STIMULATION OF ELASTOGENESIS
Embodiments provide methods for using ascorbate for the stimulation of production of elastic fibers by cells.
COMPOSITION FOR AN IMMUNOMODULATION
The present invention relates to a composition for the immunomodulation and uses and methods associated therewith.
MEDICAL USE OF COMPOUND FROM GARCINIA ESCULENTA
The present invention provides compound extracted from Garcinia species and the use of said compound in preventing and treating cancer.
Compositions and Methods For Treating Brain Injury and Brain Diseases
The present disclosure provides methods of treating brain injuries or conditions, or symptoms of brain injuries or conditions, including intranasal...
The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake...
CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
Chemical entities that are curcumin derivatives, pharmaceutical compositions and methods of treatment of cancer are described.
LONG-ACTING KETOPROFEN COMPOSITIONS
The invention describes a long-acting veterinary composition comprising at least one ketoprofen ester prodrug. The composition also comprises at least one...
OMEGA-3 FATTY ACID ARTICLES OF MANUFACTURE, AND METHODS AND APPARATUS FOR
Embodiments of the present invention are directed to methods, apparatus and articles of manufacture that feature omega-3 fatty acids co-processed with...
ANTI-INFLAMMATORY OMEGA-3 SYNERGISTIC COMBINATIONS
This invention is directed to compositions having synergistic combinations of omega-3 fatty acid such as OMEGA-3 with a tomato extract lycopene, and optionally...
ANTIMICROBIAL COMPOSITIONS AND METHOD OF USE
Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including...
COMPOSITIONS AND METHODS FOR NEUROPROTECTION AND TREATMENT OF
Compositions for neuroprotection and treatment of neurodegeneration and methods of administering same. In particular, the present invention relates to...
Solid Solution Compositions and Use in Chronic Inflammation
The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a...
E-PROSTANOID RECEPTOR, PTGER3, AS A NOVEL ANTI-DIABETIC THERAPEUTIC TARGET
Provided herein are methods for increasing insulin secretion from beta cells. Also provide herein are methods comprising administering to a subject in need of...
THERAPEUTIC AND/OR PREVENTIVE AGENT COMPRISING 1-INDANSULFAMIDE DERIVATIVE
A medicine comprising a 1-indansulfamides compound such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, or ...
MATERIAL AND METHODS FOR TREATING DEVELOPMENTAL DISORDERS INCLUDING
COMORBID AND IDIOPATHIC AUTISM
Subjects who were diagnosed with either comorbid or idiopathic autism were treated with acamprosate. Patients generally showed marked improvements in primary...
FASTING MIMICKING DIET (FMD) AND GLUCOSE LOWERING DRUGS PROTECT NORMAL
CELLS AND GENERATE CANCER SENSITIZING...
A method for treating a hyperglycemia and hyperglycemia-dependent side effects in a subject undergoing chemotherapy includes a step of identifying a subject...
METHODS AND COMPOSITIONS FOR INCREASING ENERGY EXPENDITURE USING
Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the...
FORMULATIONS FOR INHIBITION OF pcsk9 FOR THE TREATMENT OF
Described herein are pharmaceutical formulations for the treatment of hypercholesterolemia, comprising nanoparticles having a polymeric hydrophobic core which...
POLYMER-COATED THERAPEUTIC NANOPARTICLES
Polymer-coated therapeutic nanoparticles, methods of making and using the same are provided. The polymer-coated therapeutic nanoparticles can include an inner...
MODULAR PARTICLES FOR IMMUNOTHERAPY
Nanoparticulate compositions are disclosed. The nanoparticulate compositions typically include at least one, preferably two or more, active agent(s), one of...
Burst Drug Release Compositions
Solid dose compositions comprising at least one low solubility pharmaceutically active ingredient, at least one low solubility filler and at least one...
FORMULATIONS CONTAINING DIACEREIN AND METHODS OF LOWERING BLOOD LEVELS OF
URIC ACID USING THE SAME
A controlled-release formulation containing diacerein or its analogs is provided. Also provided is a method of lowering blood levels of uric acid using this...
NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS FOR FABRICATING
ARTIFICIAL RED BLOOD CELLS
A plurality of artificial red blood cell particles includes each particle of the plurality being substantially monodisperse and each particle having a largest...
Compositions Containing a Biologically Active Material and a Non-Ordered
Inorganic Oxide Material and Methods...
Compositions containing a biologically active material and a non-ordered inorganic oxide material are disclosed. Methods of making and using compositions...
MEANS FOR LUNG SPECIFIC DELIVERY
The present invention is related to composition comprising a lipid composition, wherein the lipid composition consists of a cationic lipid of formula (I)...
LIPID VESICLE COMPOSITIONS AND METHODS OF USE
The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use...
STABLE PRESSURIZED AEROSOL SOLUTION COMPOSITION OF GLYCOPYRRONIUM BROMIDE
AND FORMOTEROL COMBINATION
Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof or...
STABLE PRESSURIZED AEROSOL SOLUTION COMPOSITION OF GLYCOPYRRONIUM BROMIDE
AND FORMOTEROL COMBINATION
Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof,...
SELF-FOAMING COMPOSITIONS AND METHODS
A self-foaming composition can include at least one perfluoro compound, at least one surfactant, and at least one fatty component. The composition, when...
NUTRACEUTICAL CONFECTIONARY COMPOSITION CONTAINING CAFFEINE AND L-THEANINE
In general, certain embodiments of the present disclosure provide compositions or mechanisms for oral administration of caffeine via a functional nutraceutical...
NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are...
INJECTABLE PHARMACEUTICAL COMPOSITIONS COMPRISING PROSTACYCLIN
The present invention relates to injectable pharmaceutical compositions showing improved storage stability said compositions comprising iloprost.
TRANSDERMAL CANNABINOID FORMULATIONS
The present invention includes a transdermal composition which contains a pharmaceutically effective amount of a cannabinoid for delivery of the cannabinoid to...
The invention relates to an oral film made from a copolymer of polyvinyl alcohol and polyethylene glycol and at least one gum. The oral films may further...