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Patent # Description
2016/0310605 NOVEL ALKYLATING AGENT FOR ALKYLATING TARGET WITH DRIVER ONCOGENE MUTATION
The present invention provides a novel alkylating agent specifically binding to the genetic mutation site of a driver oncogene. There are provided are a...
2016/0310604 SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY
The present invention describes small molecule ligand-drug conjugates and methods of using the small molecule ligand-drug conjugates for targeted treatment of...
2016/0310603 IMMUNOGENIC COMPOUND
The present application relates to an immunostimulatory compound comprising an immunostimulant portion and a peptide portion. The peptide portion is not a...
2016/0310602 BIOCONJUGATE MOLECULES WITH BIOLOGICAL AND TECHNO-FUNCTIONAL ACTIVITY, METHOD FOR THE PRODUCTION THEREOF AND...
The present invention regards the synthesis of bioconjugated molecules, formed between two or more of the following functional groups: sugars, prebiotics,...
2016/0310601 PREVENTION OF MOLECULAR WEIGHT REDUCTION OF THE POLYMER, IMPURITY FORMATION AND GELLING IN POLYMER COMPOSITIONS
Polymer and drug containing compositions and method of preparing such compositions are disclosed. The dispersed phase formulation has a polymer, a...
2016/0310600 Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses...
The present invention relates to a methods of preparing active compounds complexed with lipids using aqueous systems that are free of organic solvents, and...
2016/0310599 COMPOSITIONS WITH HIGH CONTENT OF SESAMIN CLASS COMPOUNDS
The present invention improves the solubility of sesamin-class compounds in fish oil and/or wheat germ oil. More specifically, .gamma.-orizanol is combined...
2016/0310598 PARENTERAL COMPOSITIONS OF BENDAMUSTINE
Described herein are parenteral compositions of bendamustine. More particularly, parenteral compositions of bendamustine are in the form of solution.
2016/0310597 Caspofungin Acetate Formulations
A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by...
2016/0310596 COMPOSITION COMPRISING FERRIC SACCHARATE AND HIGH CONCENTRATIONS OF MICROENCAPSULATED LC-PUFA WITH A REDUCED...
The present invention is directed to compositions, preferably nutritional compositions, preferably for infant, children, maternal, ageing care, elderly or...
2016/0310595 MUCOADHESIVE DENTAL GEL INCLUDING APIS
Formulations for mucoadhesive dental gel compositions including antibiotics are disclosed.
2016/0310594 SENSITIZING COMPOSITION USING ELECTROMAGNETIC WAVES FOR THERMAL THERAPY OF CANCERS, AND CANCER THERAPY USING SAME
A sensitizing composition for thermal cancer therapy using electromagnetic waves. The sensitizing composition increases sensitivity upon treatment of cancer...
2016/0310593 METHOD FOR CONTROLLED RELEASE WITH FEMTOSECOND LASER PULSES
Provided is a method for controlled release of a chemical substance in vivo with femtosecond laser pulses. The method comprises a step of injecting into the...
2016/0310592 TREATMENT WITH ANTI-VEGF ANTIBODIES
This invention concerns in general treatment of diseases and pathological conditions with anti-VEGF antibodies. More specifically, the invention concerns the...
2016/0310591 METHODS AND COMPOSITIONS FOR OVERCOMING DRUG-RESISTANCE IN CANCER BY TARGETED DELIVERY OF PRO-DRUG-NANO-POLYMERS
The present invention provides methods for targeted delivery of agents (e.g., drugs) to cells (e.g., cancer cells) using agent-polymer conjugates and...
2016/0310590 ADJUVANT COMPOSITIONS
Adjuvant compositions comprising type 1 interferon inducers, such as double-stranded RNA, in combination with antigen delivery systems and/or immunostimulatory...
2016/0310589 Glucopyranosyl Lipid A and Allergen Formulations For Sublingual Administration
The present application relates to compositions and methods for treating allergy, e.g., peanut allergy, in patients. The methods involve administering...
2016/0310588 PURIFICATION OF BACTERIAL CAPSULAR POLYSACCHARIDE BY TWO-PHASE AQUEOUS MICELLAR SYSTEM
The present invention discloses a method for purification of bacterial capsular polysaccharide at low temperature (<20.degree. C.) by salt-induced two-phase...
2016/0310587 COMPOSITION
The invention provides a composition comprising a reduced toxicity NetB epitope polypeptide and a reduced toxicity Clostridium perfringens alpha-toxin epitope...
2016/0310586 TOPK Peptides and Vaccines Including the Same
The present invention provides isolated epitope peptides derived from TOPK and immunogenic fragments thereof have an ability to induce cytotoxic T lymphocytes...
2016/0310585 MULTI-EPITOPE TARP PEPTIDE VACCINE AND USES THEREOF
Immunogenic T cell receptor .gamma. alternate reading frame protein (TARP) peptide compositions that include multiple epitopes of the TARP protein are...
2016/0310584 FORMULATIONS FOR NEOPLASIA VACCINES
The present invention relates to neoplasia vaccine or immunogenic composition formulation for the treatment or prevention of neoplasia in a subject.
2016/0310583 TUMOR ANTIGEN PEPTIDE
The purpose of the present invention is to provide: a detection agent for specifically detecting cancer stem cells; a tumor antigen peptide specifically...
2016/0310582 ID-PROTEIN TARGETED TUMOR CELL VACCINE
ID Protein targeted cancer immunotherapy. The invention provides a cell-based attenuated live tumor cell vaccine that safely produces broad cellular...
2016/0310581 ADAM10 INHIBITION TO TREAT FRAGILE X SYNDROME
The present application relates to Fragile X syndrome and the treatment thereof. It was found that ADAM10 (A Dis-integrin And Metalloproteinase domain 10), the...
2016/0310580 PHARMACEUTICAL COMPOSITIONS OF TENECTEPLASE
Pharmaceutical compositions of tenecteplase that are safe and effective in the treatment of acute ischemic stroke compared with the known compositions are...
2016/0310579 METHODS AND COMPOSITIONS FOR TREATING DISEASES
The present invention provides methods and compositions comprising ALDH2 in the treatment of a patient with toxicity resulting from ALDH2 deficiency. The...
2016/0310578 METHOD OF ACCELERATING OSTEOGENESIS
A method for promoting osteogenesis including administering a therapeutically effective amount of collagen and a calcium absorption promoter to a subject.
2016/0310577 Collagen-Based Injectable Preparations Capable of Controlling Bleeding and/or of Substituting for Platelets in...
The present invention relates to an injectable preparation comprising particles or fibrils with length less than 10 .mu.m and at least one pharmaceutically...
2016/0310576 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME
CTP-modified human growth hormone polypeptides and pharmaceutical formulations and pharmaceutical compositions comprising the same and methods of producing,...
2016/0310575 LIPIDATED INCRETIN RECEPTOR LIGAND HUMAN IMMUNOGLOBULIN FC-REGION FUSION POLYPEPTIDES
Herein is reported a fusion polypeptide comprising i) one, two, three or four incretin receptor ligand polypeptides, and ii) one human immunoglobulin...
2016/0310574 USE OF MULLERIAN INHIBITING SUBSTANCE (MIS) PROTEINS FOR CONTRACEPTION AND OVARIAN RESERVE PRESERVATION
One aspect of the invention provides a method of contraception by administering to a female subject a composition comprising Mullerian inhibiting substance...
2016/0310573 Transdiscal Administration Of Specific Inhibitors Of Pro-Inflammatory Cytokines
The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
2016/0310572 COMPOSITIONS AND METHODS TO DIAGNOSE DIABETES AND/OR TO TREAT NEGATIVE EFFECTS OF DIABETES
The present disclosure describes a genome-wide transcriptional analysis of differentially expressed genes in diabetic, non-diabetic, normal and wounded tissue....
2016/0310571 Pharmaceutical Composition Comprising Erythropoietin and Ceftriaxone and A Method for Treating Parkinson's...
The invention discloses a pharmaceutical composition for treating Parkinson's disease dementia (PDD), which including erythropoietin and ceftriaxone. The...
2016/0310570 COMBINED PREPARATIONS FOR THE TREATMENT OF CANCER
Combined preparations for the treatment of cancer are described. The combined preparations comprise: (a) LAG-3 protein, or a derivative thereof that is able to...
2016/0310569 TUSC2 THERAPIES
A method for predicting a subject's response to a TUSC2 therapy is provided. In particular, a subject's response is predicted based on the proportion of...
2016/0310568 THERAPEUTIC METHOD OF TREATMENT FOR INHIBITING TUMOR DEVELOPMENT USING TAMM-HORSFALL GLYCOPROTEIN (THP) AS...
The present invention relates to a pharmaceutical composition for inhibiting tumor development, which comprises Tamm-Horsfall glycoprotein, native or pegylated...
2016/0310567 COMPOSITIONS FOR INHIBITING VIRAL REPLICATION AND METHODS OF USE AND PRODUCTION THEREOF
Compositions for inhibiting replication of a virus in a subject (e.g., a human patient) infected with the virus or at risk of being infected with the virus...
2016/0310566 Treatment of Gum Diseases and Gum Disorders with TSG-6 Protein
A method of treating or preventing a gum disease or gum disorder or gum injury in a mammal by administering to the mammal at least one inflammation modulatory...
2016/0310565 COMPOSITIONS AND METHOD FOR CONTROLLING INFECTIONS IN NON-HUMAN MAMMALS USING ACUTE PHASE PROTEINS
The present invention relates to compositions and methods for controlling infections in non-human mammals, particularly intra-mammary infections (IMIs). The...
2016/0310564 TILAPIA PISCIDINS FOR USE IN ENHANCEMENT OF WOUND HEALING
The preset invention relates to a new method for enhancing wound healing comprising administering a subject in need thereof with a therapeutically effective...
2016/0310563 Methods for Treating Diabetic Wounds
The present invention relates to a method of treating chronic wounds using calreticulin. In particular, the invention relates to the treatment of chronic...
2016/0310562 Compositions and Methods for the Treatment of Diseases Related to the Renin-Angiotensin-System
The present invention relates to a pharmaceutical composition comprising a. at least one aspartyl aminopeptidase inhibitor and at least one ...
2016/0310561 FORMULATIONS
The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the...
2016/0310560 Low-Dose Stable Formulations of Linaclotide
The present invention relates to stable pharmaceutical compositions comprising linaclotide or pharmaceutically acceptable salts thereof, as well as to various...
2016/0310559 Delayed Release Compositions of Linaclotide
The present invention relates to delayed release pharmaceutical compositions comprising linaclotide or pharmaceutically acceptable salts thereof, as well as to...
2016/0310558 USES OF KAPPA OPIOID SYNTHETIC PEPTIDE AMIDES
The invention relates to methods of use of synthetic peptide amides that are ligands of the kappa opioid receptor in the treatment and prevention of kappa...
2016/0310557 USE OF A MODIFIED SWEET WHEY AND A MODIFIED SWEET WHEY CONTAINING INFANT FORMULA FOR PROMOTING THE POSTNATAL...
The invention relates to modified sweet whey protein (MSWP) for promoting the establishment of healthy and normal cognitive function in young mammals. In...
2016/0310556 GRAPE-BASED FUNCTIONAL BEVERAGE WITH INTERMEDIATE-SIZED POLYPHENOLS AS THE MAIN INGREDIENT CONTAINED WITHIN A...
The present technology consists of a functional beverage based on the juice of the grape Vitis vinifera of the Pais variety, enriched with polyphenols of an...
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