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Patent # Description
2016/0310455 Methods of inhibiting a bacterial virulence in a subject
Methods of inhibiting bacterial virulence in a subject are provided. The methods can include administering an effective amount of a formulation to inhibit a...
2016/0310454 LIVER X RECEPTOR AGONISTS IN THE TREATMENT OF EMPHYSEMA
The present invention provides methods and compositions for treating a subject afflicted with chronic obstructive pulmonary disease (COPD) which comprise a i)...
2016/0310453 COMBINATION OF IMMUNOTHERAPY WITH LOCAL CHEMOTHERAPY FOR THE TREATMENT OF MALIGNANCIES
The presently disclosed subject matter provides methods, compositions, and kits for the treatment of cancer using a combination treatment comprising a locally...
2016/0310452 Aerosol Formulations Comprising Formoterol Fumarate Dihydrate
The invention provides a method of producing a highly stable pharmaceutical aerosol suspension formulation suitable for use in a metered dose inhaler, the...
2016/0310451 COMBINATION CANCER TREATMENT
Described herein is TRAIL receptor targeting therapy in combination with metformin for treatment of cancer in humans. Using TRAIL receptor targeting therapy...
2016/0310450 d-Methadone for the Treatment of Psychiatric Symptoms
The present invention relates to a method of treating psychiatric symptoms in a subject having a NMDA receptor and a NE receptor which includes administering...
2016/0310449 MODIFIED RELEASE FORMULATIONS CONTAINING DRUG - ION EXCHANGE RESIN COMPLEXES
A particulate, pH-independent, modified release barrier coated drug-cation exchange resin complex comprising a core composed of a drug complexed with a...
2016/0310448 Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections
The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a...
2016/0310447 COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY INJURY OR DISEASE
A method for treating a respiratory injury or disease comprising: administering to a patient in need of treatment a pharmaceutical composition comprising a...
2016/0310446 Low Dose Topiramate/Phentermine Composition and Methods of Use Thereof
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in...
2016/0310445 PREVENTION AND COUNTERACTION OF DIET-INDUCED THROMBOSIS RISK
The use of vitamin K is provided in preparing pharmaceutical or nutraceutical products for counteracting an increased thrombosis risk caused by poor vitamin K...
2016/0310444 REDUCTION OF ADIPOSE TISSUE
Described herein, inter alia, are compositions, formulations, methods, and systems for reducing regional fat deposits and treating fat-related conditions.
2016/0310443 FOOD AND BEVERAGE COMPOSITIONS INFUSED WITH LIPOPHILIC ACTIVE AGENTS AND METHODS OF USE THEREOF
Aspects described herein relate to food and beverage compositions infused with lipophilic active agents and methods of use for the treatment of a variety of...
2016/0310442 BETACRYPTOXANTHIN COMPOSITIONS, PROCESSES FOR PREPARATION AND USES THEREOF
Compositions are described that include a betacryptoxanthin extract, rich in trans-betacryptoxanthin, which are prepared by a cost and time effective process...
2016/0310441 HYDROUS ADHESIVE PATCH
Provided is a patch providing sufficiently high absorbability of dexmedetomidine and less skin irritation. Hydrous adhesive patch comprising dexmedetomidine or a...
2016/0310440 HYPROMELLOSE-GRAFT-CHITOSAN AND METHODS THEREOF FOR SUSTAINED DRUG DELIVERY
Described herein is a drug delivery system, which is based on a novel polymer namely hypromellose-graft-chitosan (HC), useful to deliver a drug to a patient in...
2016/0310439 LIPID MICROCAPSULES PREFERABLY COMPRISING A RETINOID, AND COMPOSITION CONTAINING SAME, METHOD FOR THE...
Lipid microcapsules are described that can include at least one irritant active substance, more specifically a retinoid, in a soluble form. Also described, are...
2016/0310438 MODIFIED RELEASE FORMULATIONS CONTAINING DRUG - ION EXCHANGE RESIN COMPLEXES
A particulate, pH-independent, modified release barrier coated drug-cation exchange resin complex comprising a core composed of a drug complexed with a...
2016/0310437 TAMPER-RESISTANT FIXED DOSE COMBINATION PROVIDING FAST RELEASE OF TWO DRUGS FROM PARTICLES
A tamper-resistant pharmaceutical dosage form comprising two pharmacologically active ingredients, wherein the dosage form provides under in vitro conditions...
2016/0310436 CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITION
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure...
2016/0310435 DPP-IV INHIBITOR COMBINED WITH A FURTHER ANTIDIABETIC AGENT, TABLETS COMPRISING SUCH FORMULATIONS, THEIR USE...
The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and a partner drug, processes for the...
2016/0310434 GASTRO-RETENTIVE ORAL PHARMACEUTICAL COMPOSITIONS
The invention relates to a pharmaceutical matrix tablet which can be administered orally once or twice per day with gastro-retentive controlled release of...
2016/0310433 Acrylic Polymer Formulations
Disclosed herein are oral solid dosage forms comprising purified neutral acrylic polymer, methods of treating a disease or condition using the same, and...
2016/0310432 MISUSE PREVENTATIVE, CONTROLLED RELEASE FORMULATION
Disclosed is a misuse preventative, controlled release composition in the form of a multilayered oral dosage form. A first layer contains a plurality of...
2016/0310431 Three-Phase System for Modified Release of a Non-Steroidal Antiinflammatory
A novel pharmaceutical composition in solid form of a nonsteroidal anti-inflammatory and/or pharmaceutically acceptable salts thereof. The composition includes...
2016/0310430 ANTIBODY FORMULATIONS AND METHODS
Antibody formulations and methods useful for prophylaxis or treatment of amyloidosis, including AA amyloidosis and AL amyloidosis.
2016/0310429 TAMPER-RESISTANT DOSAGE FORM WITH IMMEDIATE RELEASE AND RESISTANCE AGAINST SOLVENT EXTRACTION
A tamper-resistant pharmaceutical dosage form comprising a multitude of particles which comprise a pharmacologically active compound, a polyalkylene oxide, and...
2016/0310428 TAMPER-RESISTANT FIXED DOSE COMBINATION PROVIDING FAST RELEASE OF TWO DRUGS FROM DIFFERENT PARTICLES
A tamper-resistant pharmaceutical dosage form comprising two pharmacologically active ingredients, wherein the dosage form provides under in vitro conditions...
2016/0310427 TAMPER-RESISTANT FIXED DOSE COMBINATION PROVIDING FAST RELEASE OF TWO DRUGS FROM PARTICLES AND A POWDER
A tamper-resistant pharmaceutical dosage form comprising two pharmacologically active ingredients, wherein the dosage form provides under in vitro conditions...
2016/0310426 MICROPARTICLES AND NANOPARTICLES HAVING NEGATIVE SURFACE CHARGES
This invention provides methods for producing a polymer particle which contains unusually high negative charges on the surface of the particle. Preferably, the...
2016/0310425 LIPOSOMAL PARTICLES, METHODS OF MAKING SAME AND USES THEREOF
Liposomes termed as small unilamellar vesicles (SUVs), can be synthesized in the 20-50 nm size range, but encounter challenges such as instability and...
2016/0310424 WNT COMPOSITIONS AND METHODS FOR PURIFICATION
Disclosed herein are methods, processes, compositions, and kits for generating bone graft materials for use at a site of bone defect that utilizes a...
2016/0310423 BROMODOMAIN INHIBITOR
Described herein is the bromodomain inhibitor 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-o- ne, including crystalline forms,...
2016/0310422 Bendamustine Solid Dispersions And Continuous Infusion
Provided herein are pharmaceutical compositions comprising nitrogen mustard, for example bendamustine hydrochloride, solid dispersions substantially free of...
2016/0310421 MULTIMODAL PARTICULATE FORMULATIONS
Multimodal particulate formulations of medicaments and methods for their use, e.g. by nasal or pulmonary administration for the treatment of various medical...
2016/0310420 CONTROLLED-RELEASE FLOATING PHARMACEUTICAL COMPOSITIONS
The invention relates to a pharmaceutical composition comprising a plurality of controlled-release coated microparticles each comprising a floating core, on...
2016/0310419 Controlled Release Dosage Form for Once Daily Administration of Dimethyl Fumarate
A controlled release dosage form containing monomethyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically...
2016/0310418 CRUSH-RESISTANT SOLID ORAL DOSAGE FORM
The present invention relates to a method of imparting crush-resistance to an oral solid dosage form comprising a drug prone to abuse, so as to prevent the...
2016/0310417 Formulations and Methods For Targeted Ocular Delivery of Therapeutic Agents
Formulations, systems, and methods of administration are provided for preferential targeted delivery of drug to ocular tissue. In embodiments, the formulation...
2016/0310416 COMPOSITIONS CONTAINING ALPHA-2-ADRENERGIC AGONIST COMPONENTS
Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components,...
2016/0310415 CONTROLLED RELEASE COMPOSITIONS FOR MODULATING FREE-RADICAL INDUCED DAMAGE AND METHODS OF USE THEREOF
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations...
2016/0310414 MICROPARTICLES, BLOOD SUBSTITUTE AND METHOD FOR FORMING SAME
A method for forming microparticles is provided. The method includes the steps of: --providing a first solution which includes at least an anion; --providing a...
2016/0310413 SOLID PHARMACEUTICAL AND VACCINE DOSE
An elongate body for parenteral injection at low velocity from a device is described. The body has at least one pointed end and comprises at least one active...
2016/0310412 MICRONEEDLE
In order to configure a microneedle to be more suitable for administering a vaccine antigen, the present invention is a formulation having a dissolving-type...
2016/0310411 RIVASTIGMINE PAMOATE, MEMANTINE PAMOATE, METHODS OF PREPARATION AND USES THEREOF
The composition containing a pamoate salt of donepezil, the method of preparation and the use thereof are disclosed.
2016/0310410 PHARMACEUTICAL COMPOSITIONS COMPRISING ARFORMOTEROL AND GLYCOPYRRONIUM
Described herein is a fixed dose pharmaceutical composition containing arformoterol or its salt and a glycopyrronium salt. Particularly, a fixed dose...
2016/0310409 TRANSMUCOSAL DELIVERY DEVICES WITH ENHANCED UPTAKE
The present invention provides methods for enhancing transmucosal uptake of a medicament, e.g., fentanyl or buprenorphine, to a subject and related devices....
2016/0310408 Compositions Comprising Antioxidant, Fluid Dispensers, and Methods Involving the Same
A composition includes a salt; a polymer; and an antioxidant. A dispenser includes a flexible container having a closed end and an opposed open end; an...
2016/0310407 ORAL CARE PRODUCT FORMULATION
A probiotic formulation includes the following: lactobacillus acidophilus comprising 15.0% to 40.0% per mass of the probiotic formulation; lactobacillus...
2016/0310406 DISPOSABLE BODY CLEANSING TOWELETTE
Disclosed are formulations and compositions comprising the formulations made up of at least tea tree oil, peppermint oil, castor oil, aloe, and lanolin. Also...
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