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Patent # Description
2016/0312306 METHODS AND COMPOSITIONS OF MOLECULAR PROFILING FOR DISEASE DIAGNOSTICS
The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression...
2016/0312305 METHODS AND COMPOSITIONS OF MOLECULAR PROFILING FOR DISEASE DIAGNOSTICS
The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression...
2016/0312304 ASSAY FOR SAFETY ASSESSMENT OF THERAPEUTIC GENETIC MANIPULATIONS, GENE THERAPY VECTORS AND COMPOUNDS
The invention is directed to methods of assessing the safety of therapeutic compounds and therapeutic genetic manipulations, including integrating gene therapy...
2016/0312303 METHODS AND COMPOSITIONS FOR THE DETECTION OF CALR MUTATIONS IN MYELOPROLIFERATIVE DISEASES
Provided herein are methods and compositions for the detection of in-frame deletion germline mutations in the CALR gene. Also provided are methods for...
2016/0312302 SINGLE CELL GENE EXPRESSION FOR DIAGNOSIS, PROGNOSIS AND IDENTIFICATION OF DRUG TARGETS
Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows...
2016/0312301 MICRORNA BIOMARKERS FOR OVARIAN CANCER
A method of diagnosing ovarian cancer in a subject is described that includes identifying the expression level of at least one diagnostic miRNA in a biological...
2016/0312300 ASSAYS AND METHODS RELATING TO THE TREATMENT OF MELANOMA
The technology described herein relates to assays and methods for the diagnosis, prognosis, and/or treatment of melanoma, e.g. relating to measuring the level...
2016/0312299 SYNTHETIC NUCLEIC ACID CONTROL MOLECULES
The present invention provides synthetic DNA strands that find use as controls or in nucleic acid testing methods. In particular, provided herein are synthetic...
2016/0312298 METHODS AND ASSAYS RELATING TO CIRCULATING TUMOR CELLS
The technology described herein relates to methods of detecting circulating tumor cells (CTCs), e.g. by detecting changes in the expression of certain CTC...
2016/0312297 PD-L1 GENE SIGNATURE BIOMARKERS OF TUMOR RESPONSE TO PD-1 ANTAGONISTS
The present disclosure describes PD-L1 gene signature biomarkers that are useful for identifying cancer patients who are most likely to benefit from treatment...
2016/0312296 DIFFERENT LEVELS IN BLOOD CELL SAMPLES OF EMT-MARKERS FOR THE DIAGNOSIS OF CANCER, IN PARTICULAR OF COLORECTAL...
The present invention concerns a method for determining if a subject is affected by a colorectal or pancreatic cancer or for determining the stage and/or the...
2016/0312295 GENE SIGNATURE BIOMARKERS OF TUMOR RESPONSE TO PD-1 ANTAGONISTS
The present disclosure describes gene signature biomarkers that are useful for identifying cancer patients who are most likely to benefit from treatment with a...
2016/0312294 PROSTATE CANCER CLASSIFICATION
A method is provided for characterising and/or prognosing prostate cancer in a subject comprising determining the expression level of at least one of CREM,...
2016/0312293 A METHOD OF PREDICTING A RESPONSE TO AN ANTI-TUMOR TREATMENT
The invention provides an in vitro method for determining the likelihood for a patient affected with a tumor to respond to a treatment with a pro-apoptotic...
2016/0312292 METHODS FOR TREATING HEMATOLOGICAL CANCERS AND THE USE OF BIOMARKERS AS A PREDICTOR OF CLINICAL SENSITIVITY TO...
Provided herein, in certain embodiments, are biomarkers for use in predicting the clinical sensitivity of hematologic cancers, such as non-Hodgkin's lymphoma,...
2016/0312291 NOVEL RNA-BIOMARKERS FOR DIAGNOSIS OF PROSTATE CANCER
The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the...
2016/0312290 USE AND IDENTIFICATION OF BIOMARKERS FOR GASTROINTESTINAL DISEASES
The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug...
2016/0312289 BIOMOLECULAR EVENTS IN CANCER REVEALED BY ATTRACTOR MOLECULAR SIGNATURES
The present invention is directed to compositions and methods for the independent and unconstrained identification of attractor molecular signatures as...
2016/0312288 NOVEL NRG1 FUSION GENES IN CANCER
The present invention relates to novel fusion genes comprising NRG1 and a further fusion partner, like CD74. The present invention provides for the use of...
2016/0312287 Methods and nucleic acids for the analysis of gene expression associated with the prognosis of prostate cell...
Particular aspects provide novel methods and compositions (e.g., nucleic acids, kits, etc.) having substantial utility for providing a prognosis of prostate...
2016/0312286 BIOMARKER IDENTIFICATION
Disclosed are method and apparatus for identifying biomarkers and in particular for identifying biomarkers for use in making clinical assessments, such as...
2016/0312285 METHODS OF IDENTIFYING AND TREATING SUBJECTS HAVING ACUTE RESPIRATORY DISTRESS SYNDROME
The present invention is related to novel methods for categorizing and treating subjects having Acute Respiratory Distress Syndrome (ARDS).
2016/0312284 SELECT SINGLE NUCLEOTIDE POLYMORPHISMS PREDICTIVE OF RESPONSE TO GLATIRAMER ACETATE
The present invention provides a method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple...
2016/0312283 DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC USES OF LONG NONCODING RNAS FOR HEART DISEASE AND REGENERATIVE MEDICINE
This invention generally relates to lncRNAs and methods for diagnosing cardiac pathologies in a subject. The invention also provides methods for treating a...
2016/0312282 MOLECULAR DIAGNOSTIC PANEL OF EOSINOPHILIC GASTROINTESTINAL DISORDERS
The disclosure provides compositions and methods related to the diagnosis, prognosis, and treatment of inflammatory diseases and disorders, especially allergic...
2016/0312281 METHODS AND PROBES FOR IDENTIFYING GENE ALLELES
The present invention relates to a method of genotyping highly polymorphic nucleic acid. In particular, the present disclosure relates to methods for...
2016/0312280 Compositions And Methods Of Nucleic Acid-Targeting Nucleic Acids
This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof.
2016/0312279 PYROSEQUENCING METHODS AND RELATED COMPOSITIONS
This invention provides methods for pyrosequencing and compositions comprising 3'-O-modified deoxynucleoside triphosphates.
2016/0312278 MULTIPLEXED METHOD FOR THE IDENTIFICATION AND QUANTITATION OF MINOR ALLELES AND POLYMORPHISMS
Provided herein are products and processes for detecting the presence or absence of minor nucleic acid species in a sample containing a mixture of minor...
2016/0312277 AMPLIFICATION AND DETECTION OF RIBONUCLEIC ACIDS
Compositions, methods, and kits for detecting one or more species of RNA molecules are disclosed. In one embodiment, a first adaptor and a second adaptor are...
2016/0312276 METHODS AND COMPOSITIONS FOR WHOLE TRANSCRIPTOME AMPLIFICATION
The disclosure provides for methods, compositions, systems, devices, and kits for whole transcriptome amplification using stochastic barcodes.
2016/0312275 HIGH RESOLUTION SYSTEMS, KITS, APPARATUS, AND METHODS FOR HIGH THROUGHPUT MICROBIOLOGY APPLICATIONS
A microfabricated device defining a high density array of microwells is described for cultivating cells from a sample. A series of unique tags may be disposed...
2016/0312274 METHODS AND SYSTEMS FOR VOLUME VARIATION MODELING IN DIGITAL PCR
A method for performing digital polymerase chain reaction (dPCR) is provided. The method includes partitioning a biological sample volume including a plurality...
2016/0312273 HiC: Method of Identifying Interactions Between Genomic Loci
The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to,...
2016/0312272 METHODS AND COMPOSITIONS RELATING TO OPTICAL SUPER-RESOLUTION PATTERNING
This disclosure provides methods for generating super-resolution patterns of molecules on substrates. In one aspect, disclosed herein is a method comprising...
2016/0312271 DETECTION OF TARGET NUCLEIC ACID SEQUENCES BY PTO CLEAVAGE AND EXTENSION ASSAY
The present invention relates to the detection of a target nucleic acid sequence by a PTOCE (PTO Cleavage and Extension) assay. The present invention detects a...
2016/0312270 LPS SEROTYPES FOR DETERMINING SEVERITY OF URINARY TRACT INFECTION
A method of identifying a subject having a urinary tract infection posing a significant risk of dangerous sequalae is described. The method includes obtaining...
2016/0312269 Mycobacteria Detection Using Bacteriophages
A method for testing for target Mycobacteria in a reaction mixture comprising the steps of: providing a reaction mixture; admixing a bacteriophage with the...
2016/0312268 METHOD OF PREPARING A REACTION MIXTURE AND RELATED PRODUCTS
The invention relates to a method of preparing a reaction mixture for Polymerase Chain Reaction (PCR) assay and a solution set for PCR. The method comprises...
2016/0312267 Mapping cell identity determinants in chromatin
The invention provides materials and methods to identify and analyze in a genome-wide manner the structural determinants of this organization. Next generation...
2016/0312266 METHODS FOR AUTOMATED CAPTURE AND PURIFICATION OF MULTIPLE NUCLEIC ACID TARGETS FROM STOOL SAMPLES
Provided herein is technology relating to automated capture and purify nucleic acids from biological samples. In particular, the technology relates to methods...
2016/0312265 USE OF NUCLEIC ACID AGENTS FOR ULTRA-SENSITIVE DIGITAL DETECTION AND QUANTIFICATION OF TARGET MOLECULES
Described herein are methods and systems for detecting and quantifying target molecules and particles in a sample using a plurality of capture objects and a...
2016/0312264 ANALYSIS OF AMINO ACID COPOLYMER COMPOSITIONS
Methods for analyzing, selecting, characterizing or classifying compositions of a co-polymer, e.g., glatiramer acetate are described. The methods entail...
2016/0312263 BIOLOGICAL INDICATOR
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene...
2016/0312262 BIOMIMETIC VIRUS-BASED COLORIMETRIC SENSORS
The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a...
2016/0312261 ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES
The invention relates to the enzymatic production of cytosinic nucleoside analogues. In particular it relates to a new synthesis process of cytosine nucleoside...
2016/0312260 Synthesis of Transcripts Using Syn5 RNA Polymerase
Methods of in vitro transcription using cyanophage Syn5 RNA polymerase (RNAP) or mutants thereof and transcription conditions are provided.
2016/0312259 METHOD OF PROCESSING LIGNOCELLULOSIC MATERIAL USING AN ALKALINE DELIGNIFICATION AGENT
The present invention relates to a method for obtaining sugar and lignin fractions from lignocellulosic materials and to a method for producing fermentation...
2016/0312258 METHOD FOR PRODUCING FERMENTATION-RAW-MATERIAL SUGAR SOLUTION AND METHOD FOR PRODUCING CHEMICAL OBTAINED BY...
A method for producing a fermentation-raw-material sugar solution includes a step of saccharifying non-food biomass to obtain a ...
2016/0312257 METHODS OF PROCESSING AROMATIC COMPOUNDS
A method of processing a solution comprising aromatic compounds. The method includes culturing a first microorganism in the solution for a time sufficient to...
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