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METHODS OF T CELL EPITOPE PROFILING, MAKING T CELL COMPOSITIONS, AND
Disclosed herein is a method of detecting antigen specific T cells in a sample isolated from a subject and mapping immunostimulatory epitopes of the antigen....
DETECTION OF NUT ALLERGIES
The present invention relates to a polypeptide comprising an antigenic fragment having a sequence of at least seven amino acids from a hydrophilic domain of an...
DETECTION OF AN ANTIBODY AGAINST A PATHOGEN
Provided herein are methods of detecting an antibody directed against a pathogen and uses thereof. One aspect provided herein relates to a method for detecting...
Risk Assessment for Therapeutic Drugs
Methods to estimate safety and/or efficacy of therapeutic drugs, which include portable devices for anti-drug antibody (ADA) testing and databases containing...
SERUM ANTIBODY ASSAY FOR DETERMINING PROTECTION FROM MALARIA, AND
PRE-ERYTHROCYTIC SUBUNIT VACCINES
Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such...
SIMULTANEOUS CHARACTERIZATION OF IgG AND IgA ANTIBODIES TOMULTIPLE FOOD
ANTIGENS AND C1Q-FOOD PROTEIN IMMUNE...
Compositions and methods for accurately characterizing immune reactivity to food allergens have been developed, in which test surfaces that incorporate...
HIGH-AFFINITY SMALL MOLECULE FORMYLPEPTIDE RECEPTOR LIGANDS FROM SCREENING
OF COMBINATORIAL MIXTURE-BASED LIBRARIES
The present invention provides novel methods and assays for high-throughput screening of combinatorial libraries to identify FPR1 and/or FPR2 ligands (e.g.,...
METHOD AND APPARATUS FOR SIGNAL TRANSDUCTION PATHWAY PROFILING
An assay device for determining the presence of analytes in a cell lysate comprises a porous support member and a plurality of binding reagents arranged and...
The invention relates to biosensors, more particularly to protein biosensors and their use to indicate the formation of denaturing ice crystals in samples. The...
MACROCYCLIC HOPO CHELATORS
The present invention provides a novel class of macrocyclic compounds as well as complexes formed between a metal (e.g., lanthanide) ion and the compounds of...
SRM/MRM Assay for Subtyping Lung Histology
The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the KRT5, KRT7, NapsinA, TTF1, TP63, and/or...
USE OF BUBR1 AS A BIOMARKER OF DRUG RESPONSE TO FURAZANOBENZIMIDAZOLES
Use of BUBR1 as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject, wherein the compound is...
METHODS FOR DETECTING AND TREATING CANCER
The invention generally features compositions and methods for the diagnosis, treatment, and monitoring of neoplasia in a subject, as well as methods of...
MATERIALS AND METHODS FOR DIAGNOSIS AND PROGNOSIS OF LIVER CANCER
The invention relates to materials and methods for diagnosing liver tumor types, and assessing patient prognosis. Specifically, but not exclusively, the...
COMPOSITIONS AND METHODS FOR ACTIVE SURVEILLANCE OF PROSTATE CANCER
Aspects of the disclosure relate to improved methods and systems for active surveillance of subject having non-aggressive prostate cancer.
Methods And Marker Combinations For Screening For Predisposition To Lung
The present invention relates to rapid, sensitive methods for determining whether a subject is at risk of developing lung cancer or has lung cancer based on...
IMMUNOSIGNATURE BASED DIAGNOSIS AND CHARACTERIZATION OF CANINE LYMPHOMA
Methods for diagnosing and characterizing lymphoma, as well as evaluating the disease-free interval following treatment, utilizing patient antibodies bound to...
COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING HOST CELL PROTEIN
IN CELL LINES AND RECOMBINANT...
Monoclonal and polyclonal antibodies that bind hamster phospholipase B-like 2 are provided. Also provided are methods for detecting and quantifying hamster...
COMPOSITIONS AND METHODS FOR CAPTURING EXOSOMES
Compositions and kits for exosome capture include an antibody specifically binding the human asparagine-linked glycosylation 6 homolog (ALG6). The compositions...
Immunoassay for Detection of Virus-Antibody Nanocomplexes in Solution by
Chip-Based Pillar Array
Techniques for detection of virus-antibody nanocomplexes using a chip-based pillar array are provided. In one aspect, a method for virus detection is provided....
BIOMARKERS AND USES THEREOF
The present invention provides markers of regulatory T (Treg) cells, preferably, cell surface markers of Treg cells and uses of those markers or compounds that...
METHOD FOR DETECTING COLIFORM BACTERIA CONTAINED IN MILK
The object is to provide a lysis method, lysis treatment solution, detection method using an immunochromatographic device, and detection kit comprising an...
MYCOBACTERIUM TUBERCULOSIS SPECIFIC PEPTIDES FOR DETECTION OF INFECTION OR
IMMUNIZATION IN NON-HUMAN PRIMATES
The present invention relates to novel peptides that may be used in whole or in combination for the detection of Mycobacterium tuberculosis infection. In...
DETERMINATION OF LEVELS OF IMMUNOGENIC GLUTEN PEPTIDES IN HUMAN SAMPLES
FIELD OF THE INVENTION
The present invention fitted in the medical-clinical sector, shows a method for monitoring the ingestion of gluten by measuring protein/gluten peptides present...
METHODS FOR ASSAYING IMMUNOLOGICAL COMPETENCE
A method of assaying or monitoring the determining immunological competence of a subject, particularly for determining immunological competence in a subject,...
METHOD AND APPARATUS FOR ELECTROCHEMICAL DETECTION
The invention provides an apparatus and methods for the electrochemical detection and/or quantitation of an analyte in a sample, wherein the device comprises a...
LATERAL FLOW ASSAY DEVICES FOR USE IN CLINICAL DIAGNOSTIC APPARATUS AND
CONFIGURATION OF CLINICAL DIAGNOSTIC...
A lateral flow device for use in a mainframe or point-of-care clinical analyzer, in which the lateral flow device includes a planar support having at least one...
SYSTEMS AND METHODS FOR MULTI-ANALYSIS
Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample...
GOLD ION BEAM DRILLED NANOPORES MODIFIED WITH THIOLATED DNA ORIGAMIS
A nanopore structure includes an aperture extending from a first surface to a second surface of a substrate, the aperture having a wall comprising gold ions...
Magnetic-nanoparticle conjugates and methods of use
The present invention provides novel compositions of binding moiety-nanoparticle conjugates, aggregates of these conjugates, and novel methods of using these...
Bead Incubation and Washing on a Droplet Actuator
The invention relates to bead incubating and washing on a droplet actuator. Methods for incubating magnetically responsive beads that are labeled with primary...
METHOD FOR PROTEIN ANALYSIS
The present invention relates to a method for protein analysis in which the proteins to be analyzed are displayed on a population of discrete and dispersible...
STABLE NANOMAGNETIC PARTICLE DISPERSIONS
Processes and compositions are described for preparing new, colloidally stable, coated nanomagnetic particles useful for both in-vitro and in-vivo biomedical...
METHOD OF DETECTING TEST SUBSTANCE, SAMPLE ANALYSIS CARTRIDGE, AND SAMPLE
In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge...
MICROFLUIDICS BASED ASSAY DEVICE
A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection...
Re-Usable Analyte Detector and Methods
Devices and methods for detecting the presence of one or more analytes, such as biomolecules (FIG. 2). An analyte detection device includes at least two...
CARBOXY X RHODAMINE ANALOGS
The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and...
ONLINE DIAGNOSTIC SYSTEM WITH VIRTUAL MEDICAL ASSISTANCE FOR THE DIAGNOSED
DISEASE UTILIZING NANO-DEVICES AND...
The present invention relates to implementing an online diagnostic system for diagnosing the sample received from a client. The system is connected with an...
COMPOSITIONS AND METHODS FOR IN VITRO ASSAYS OF FIBRIN ACTIVITY
The present invention provides compositions exhibiting in vivo activity of fibrin in an in vitro setting, in vitro assays comprising such compositions, methods...
METHOD AND APPARATUS FOR PERFORMING HEMATOLOGIC ANALYSIS USING AN
ARRAY-IMAGING SYSTEM FOR IMAGING AND ANALYSIS...
A method and device for analyzing a hematologic sample centrifuged within a capillary tube is provided. The device includes a tube holder, a sample imaging...
METHOD AND APPARATUS FOR PREDICTING EFFECTIVE DOSE OR SENSITIVITY OF
An object of the present invention is to provide a method and apparatus for predicting an effective dose of or the sensitivity to ...
METHODS AND DEVICES FOR QUANTITATING BLOOD SAMPLES
Methods and devices for analysing blood sample volumes are provided. In particular, the disclosure provides a method for estimating the volume of a blood...
METHODS FOR THE DIAGNOSIS AND RISK ASSESSMENT OF PLASMALOGEN DEFICIENCY
MEDIATED DISEASES OF AGING
The present invention relates to methods for the diagnosis and risk assessment of plasmalogen deficiency mediated diseases of aging. The present invention...
CELL POTENTIAL MEASURING ELECTRODE ASSEMBLY AND METHOD FOR MEASURING
ELECTRIC POTENTIAL CHANGE OF CELL USING...
The present invention provides a cell potential measuring electrode assembly comprising: an insulating substrate; a conductive pattern arranged in the...
NANO-GAP ELECTRODE PAIR AND METHOD OF MANUFACTURING SAME
A system for detecting a biomolecule comprises a nano-gap electrode device including a first electrode and a second electrode adjacent to the first electrode....
Method for Determining the Bulk Modulus of Fuels
A method for determination of the bulk modulus of fuels in a fuel system of a combustion engine (2) with a common rail injection system (6), with a high...
Method and Apparatus for Reducing Gas Consumption
A gas transport system includes at least one chemical reactor having at least one inlet and at least one gas outlet and at least one sample introduction unit...
The present invention relates to a gas detector cell and cell unit for optical detection of a predetermined gas, the cell being provided with optical means for...
COMBUSTION OPTIMIZATION SYSTEM AND METHOD
A combustion optimization system is disclosed. The system includes a boiler having a plurality of zonal locations, a sensor grid comprising a plurality of...
SYSTEM AND METHOD FOR MONITORING CONTAMINATIONS
A system for monitoring contaminations includes a moisture-containing chilating gas supply adapted to provide a moisture-containing chilating gas mixing with a...