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Patent # Description
2016/0319358 METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR ENDOCRINE SYSTEM CONDITIONS
A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an...
2016/0319357 METHODS FOR MULTIPLEX DETECTION OF ALLELES ASSOCIATED WITH OPHTHALMIC CONDITIONS
Systems and methods for detecting at least two genomic alleles associated with corneal dystrophy in a sample from a human subject are disclosed in which cells...
2016/0319356 FIG4 GENE MUTATIONS IN NEURODEGENERATION
The present invention relates to neuropathy, in particular to mutations in the FIG4 gene. The present invention also provides assays for the detection of...
2016/0319355 PREDICTING THERAPEUTIC RESPONSE IN PARKINSON'S DISEASE
Provided herein are methods and compositions for determining the susceptibility of Parkinson's disease patients to optimized drug therapy (ODT) and or deep...
2016/0319354 SYSTEMS, COMPOSITIONS AND METHODS FOR DETECTING AND ANALYZING MICRO-RNA PROFILES FROM A BIOLOGICAL SAMPLE
Methods and apparatuses for detecting microRNA from a tissue sample. In particular, described herein are multiplexed methods and apparatuses for implementing...
2016/0319353 AP5B1 AS A NEW MARKER FOR MODERATE TO SEVERE ACNE
The invention relates to the identification of Adaptor-Related Protein Complex 5, subunit 1 (AP5B1) as a biomarker of moderate to severe acne. The invention...
2016/0319352 GENETIC POLYMORPHISMS ASSOCIATED WITH MYOCARDIAL INFARCTION, METHODS OF DETECTION AND USES THEREOF
The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention...
2016/0319351 GENETIC VARIANTS AS MARKERS FOR USE IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF EOSINOPHILIA, ASTHMA AND...
Polymorphic variants (e.g., certain alleles of polymorphic markers) that have been found to be associated with high blood eosinophil counts, conditions...
2016/0319350 FLUIDIC SYSTEM FOR REAGENT DELIVERY TO A FLOW CELL
A fluidic system that includes a reagent manifold comprising a plurality of channels configured for fluid communication between a reagent cartridge and an...
2016/0319349 Compositions And Methods Of Nucleic Acid-Targeting Nucleic Acids
This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof. Genome engineering can refer...
2016/0319348 HIGH THROUGHPUT SEQUENCING OF PAIRED VH AND VL TRANSCRIPTS FROM B CELLS SECRETING ANTIGEN-SPECIFIC ANTIBODIES
Methods for determining the VH:VL antibody repertoire from cells, such as antigen-specific B cells, in a high throughput manner. In some aspects, methods are...
2016/0319347 SYSTEMS AND METHODS FOR DETECTION OF GENOMIC VARIANTS
The invention relates to the detection of genomic variants using next generation sequencing platforms, and increasing the positive predictive value and/or...
2016/0319346 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS
The invention provides a novel additive for improved analysis by mass spectrometry. More specifically, ascorbic acid has been found to reduce or eliminate the...
2016/0319345 ERROR SUPPRESSION IN SEQUENCED DNA FRAGMENTS USING REDUNDANT READS WITH UNIQUE MOLECULAR INDICES (UMIS)
The disclosed embodiments concern methods, apparatus, systems and computer program products for determining sequences of interest using unique molecular index...
2016/0319344 NANOPORE SEQUENCING USING REPLICATIVE POLYMERASES AND HELICASES
The present invention relates to a system of nanopore sequencing using nucleic-acid binding proteins wherein the activity of the said protein and the passage...
2016/0319343 REAL-TIME REDOX SEQUENCING METHODS
Real time redox sequencing methods, devices, and systems are described. Arrays of redox devices comprising one or two electrodes are used to provide sequence...
2016/0319342 BIOMOLECULE SEQUENCING DEVICES, SYSTEMS AND METHODS
Devices, systems and methods for sequencing protein samples are provided. In some examples, currents generated when a monomer passes through between electrodes...
2016/0319341 Method and Compositions for Detection and Enumeration of Genetic Variations
Many areas of biomedical research depend on the analysis of uncommon variations in individual genes or transcripts. Here we describe a method that can quantify...
2016/0319340 COMPOSITIONS AND METHOD FOR MEASURING AND CALIBRATING AMPLIFICATION BIAS IN MULTIPLEXED PCR REACTIONS
Compositions and methods are described for standardizing the DNA amplification efficiencies of a highly heterogeneous set of oligonucleotide primers as may...
2016/0319339 Copy Number Analysis of Genetic Locus
Systems and methods for analyzing copy number of a target locus, detecting a disease associated with abnormal copy number of a target gene or a carrier thereof.
2016/0319338 METHODS OF DEPLETING A TARGET NUCLEIC ACID IN A SAMPLE AND KITS FOR PRACTICING THE SAME
Provided are methods of depleting a target nucleic acid in a sample. The methods include contacting a target nucleic acid with two or more polymers that...
2016/0319337 METHODS TO REDUCE EVAPORATION DURING ELEVATED TEMPERATURE
A method including contacting a tissue or cellular sample with a reagent including an evaporation reducing agent(s) having the general formula ...
2016/0319336 ALLELE AMPLIFICATION BIAS
Methods are provided for nucleic acid analysis. In an illustrative method, allele amplification bias is used to amplify preferentially a target nucleic acid...
2016/0319335 METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
2016/0319334 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions,...
2016/0319333 Nanopore-Facilitated Single Molecule Detection of Nucleic Acids
The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary...
2016/0319332 NON-CODING RNA OF SALMONELLA AND IDENTIFICATION AND USE THEREOF
The present invention provides Salmonella non-coding RNA and the identification and application thereof. In particular, the present invention proves through...
2016/0319331 FAST PCR HEATING
Provided herein is a microplate for polymerase chain reaction (PCR), comprising a substrate formed of a material that is susceptible to heating PCR samples...
2016/0319330 METHOD AND APPARATUS FOR ANALYZING BIOMOLECULES BY USING OLIGONUCLEOTIDE
The present invention relates to a method for analyzing biomolecules by using an oligonucleotide, and specifically, provides a method and an apparatus for...
2016/0319329 DYNAMIC ASSAY SELECTION AND SAMPLE PREPARATION APPARATUS AND METHODS AND MACHINE-READABLE MEDIUMS THEREOF
Automated methods of preparing patient samples for assays are disclosed. The methods include performing sample processing of multiple patient samples in...
2016/0319328 HIGH-THROUGHPUT AND HIGHLY MULTIPLEXED IMAGING WITH PROGRAMMABLE NUCLEIC ACID PROBES
The present invention provides, inter alia, methods and compositions for imaging, at high spatial resolution, targets of interest.
2016/0319327 PORTABLE GENETIC DETECTION AND ANALYSIS SYSTEM AND METHOD
A portable detector is disclosed for detecting certain analytes of interest, such as genetic material (e.g., nucleic acids). The detector includes a reading...
2016/0319326 USE OF AT LEAST ONE SUBSTRATE OF CARBOXYLESTERASE AND/OR TRIACYLGLYCEROL LIPASE FOR DETECTING BACTERIA OF THE...
Use of at least one chromogenic and/or fluorogenic carboxylesterase and/or triacylglycerol-lipase substrate, to detect bacteria of the Bacillus cereus group in...
2016/0319325 Swatch for Testing Lipase Activity
The present invention provides a swatch comprising a fabric and a colored lipid stain, wherein said colored lipid stain comprises one or more of several lipase...
2016/0319324 MODULATORS OF GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE PROTEINS
The present invention relates to glycerophosphodiester phosphodiesterase (GDE) proteins. More specifically, the present invention relates to targeting GDE...
2016/0319323 METHOD FOR DETERMINING SITE HAVING N-LINKED SUGAR CHAIN ADDED THERETO OR PROPORTION OF SAID ADDITION
A method for detecting a site which can be modified with an N-linked glycan chain and to which an N-linked glycan chain is actually linked in a glycoprotein;...
2016/0319322 PATHOGEN DETECTION
A device for detecting bacteria in a sample, comprising: a substrate having a surface; and a plurality of Fe(III)-bound or Fe(III)-binding siderophores...
2016/0319321 ENTEROKINASE CLEAVABLE POLYPEPTIDES
The present invention relates to Enterokinase-cleavable polypeptides comprising an Enterokinase cleavage site connected to a polypeptide and their use for...
2016/0319320 RECOMBINANT PRODUCTION OF MIXTURES OF ANTIBODIES
Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic...
2016/0319319 METHOD FOR THE RECOMBINANT PRODUCTION OF A POLYPEPTIDE IN PROKARYOTIC CELLS
Herein is reported a method for the recombinant production of a polypeptide in E. coli comprising the steps of i) cultivating an NADH dehydrogenase...
2016/0319318 PROCESS FOR THE PREPARATION OF TIACUMICIN
The present invention relates to the preparation of Tiacumicin B from a Dactylosporangium or Actinoplanes strain capable of producing Tiacumicin B utilizing...
2016/0319317 METHOD FOR USING HEXENOL GLYCOSYL TRANSFERASE
The object of the present invention is to provide a method for producing a hexenol glycoside by means of hexenol glycosyltransferase. The present invention...
2016/0319316 METHOD FOR PRODUCING FRUCTOSE-ADDED CARBOHYDRATE
[Problem] To provide a production method capable of simply and efficiently producing a fructose-added carbohydrate using .beta.-fructofuranosidase. [Solution] A...
2016/0319315 Methods for Degrading or Converting Cellulosic Material
A method for degrading or converting a cellulosic material is provided, comprising (a) subjecting the cellulosic material to an enzyme composition at a mild...
2016/0319314 COMPOSITIONS AND METHODS FOR PRODUCING BENZYLISOQUINOLINE ALKALOIDS
The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and...
2016/0319313 MICROORGANISMS AND METHODS FOR THE COPRODUCTION 1,4-BUTANEDIOL AND GAMMA-BUTYROLACTONE
The invention provides non-naturally occurring microbial organisms comprising 1,4-butanediol (14-BDO) and gamma-butyrolactone (GBL) pathways comprising at...
2016/0319312 SYNTHESIS METHOD FOR L-CYCLIC ALKYL AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF
A synthesis method for L-cyclic alkyl amino acid and a pharmaceutical composition having the said amino acid are provide in the present disclosure provides....
2016/0319311 BIOCHEMICAL SYNTHESIS OF 1,4-BUTANEDIAMINE
The invention relates to a process for biochemical synthesis of 1,4-butanediamine in a microorganism having an increased level of an ornithine decarboxylase...
2016/0319310 METHOD OF PROCESSING LIGNOCELLULOSIC MATERIAL USING A CATIONIC COMPOUND
The present disclosure relates to a method for obtaining sugar and lignin fractions from lignocellulosic materials and to a method for producing fermentation...
2016/0319309 FERMENTATION PROCESS FOR THE PRODUCTION OF ORGANIC ACIDS
This invention relates to improvements in the fermentation process used in the production of organic acids from biological feedstock using bacterial catalysts....
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